Derek J. Parks

11.9k citations

42 papers · 9.5k indexed · 7 hit papers · h-index 29

Impact in

Pharmacology top 0.1%
- Pharmacogenetics and Drug Metabolism
Oncology top 0.5%
- Drug Transport and Resistance Mechanisms

Papers in

Biochemistry 5
- Eicosanoids and Hypertension Pharmacology 5
Pharmacology 6
- Pharmacogenetics and Drug Metabolism 6

Co-authors: Timothy M. Willson Steven A. Kliewer Steven G. Blanchard Randy K. Bledsoe Thomas G. Consler Julie B. Stimmel Jürgen M. Lehmann Millard H. Lambert
Journals: Bioorganic & Medicinal Chemistry Letters (9 papers)Journal of Medicinal Chemistry (9 papers)Journal of Biological Chemistry (3 papers)Antimicrobial Agents and Chemotherapy (2 papers)Analytical Biochemistry (2 papers)
Partner nations: United States Netherlands United Kingdom

In The Last Decade

Derek J. Parks

41 papers receiving 9.2k citations

Hit Papers

7 papers align trajectories log scale

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways 2007 · 572 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Science
2002 Cell
2002 Nature
2002 Journal of Medicinal Chemistry
2000 Journal of Biological Chemistry
1999 Science
1999 Molecular Cell

Peers

Countries citing papers authored by Derek J. Parks

Since Specialization

Citations

This map shows the geographic impact of Derek J. Parks's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Derek J. Parks with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Derek J. Parks more than expected).

Fields of papers citing papers by Derek J. Parks

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Derek J. Parks. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Derek J. Parks. The network helps show where Derek J. Parks may publish in the future.

Co-authors

The 25 scholars most cited alongside Derek J. Parks, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Derek J. Parks Line = papers co-authored together Derek J. Parks links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists Bioorganic & Medicinal Chemistry Letters ·Terrence L. Smalley, Sharon Boggs, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, István Káldor, Derek J. Parks	2014	15
2	Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene Bioorganic & Medicinal Chemistry Letters ·Adwoa Akwabi-Ameyaw, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	2011	28
3	Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction Nature Structural & Molecular Biology ·Caroline A. Phelan, Robert T. Gampe, Millard H. Lambert, Derek J. Parks, Valerie G. Montana, Jane M. Bynum, Timothy M Broderick, Xiao Hu, Shawn P. Williams, Robert T. Nolte, Mitchell A. Lazar	2010	68
4	Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene Bioorganic & Medicinal Chemistry Letters ·Jonathan Y. Bass, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Wendy Y. Mills, Frank Navas, Derek J. Parks, Terrence L. Smalley, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	2010	53
5	Synthesis and SAR of potent LXR agonists containing an indole pharmacophore Bioorganic & Medicinal Chemistry Letters ·David G. Washburn, Tram H. Hoang, Nino Campobasso, Angela Smallwood, Derek J. Parks, Christine L. Webb, Kelly Frank, Melanie Nord, Chaya Duraiswami, Christopher A. Evans, Michael Jaye, Scott K. Thompson	2009	15
6	Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064 Bioorganic & Medicinal Chemistry Letters ·Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Derek J. Parks, Dan Todd, Shawn P. Williams, G. Bruce Wisely	2009	45
7	FXR agonist activity of conformationally constrained analogs of GW 4064 Bioorganic & Medicinal Chemistry Letters ·Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	2009	56
8	The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages Bioorganic & Medicinal Chemistry Letters ·Joseph P. Marino, Lara S. Kallander, Chun Ma, Hye-Ja Oh, Dennis Lee, Dimitri E. Gaitanopoulos, John A. Krawiec, Derek J. Parks, Christine L. Webb, Kelly Ziegler, Michael Jaye, Scott K. Thompson	2009	6
9	Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064 Bioorganic & Medicinal Chemistry Letters ·Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Stacey A. Jones, István Káldor, Yaping Liu, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	2008	118
10	Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways Science ·Lei Yin, Nan Wu, Joshua C. Curtin, Mohammed Qatanani, Nava Szwergold, Robert A. Reid, Gregory M. Waitt, Derek J. Parks, Kenneth H. Pearce, G. Bruce Wisely, Mitchell A. Lazar Hit paper breakdown →	2007	572
11	X-ray Crystal Structure of the Liver X Receptor β Ligand Binding Domain Journal of Biological Chemistry ·Shawn P. Williams, Randy K. Bledsoe, Jon L. Collins, Sharon Boggs, Millard H. Lambert, Ann B. Miller, John T. Moore, David D. McKee, Linda B. Moore, Jason A. Nichols, Derek J. Parks, Mike Watson, Bruce Wisely, Timothy M. Willson	2003	170
12	Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes Journal of Biological Chemistry ·Jodi M. Maglich, Derek J. Parks, Linda B. Moore, Jon L. Collins, Bryan Goodwin, Andrew N. Billin, Catherine A. Stoltz, Steven A. Kliewer, Millard H. Lambert, Timothy M. Willson, John T. Moore	2003	351
13	Cell-Free Ligand Binding Assays for Nuclear Receptors Methods in enzymology on CD-ROM/Methods in enzymology ·Stacey A. Jones, Derek J. Parks, Steven A. Kliewer	2003	3
14	Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition Cell ·Randy K. Bledsoe, Valerie G. Montana, Thomas B. Stanley, Chris J. Delves, C.J. Apolito, David D. McKee, Thomas G. Consler, Derek J. Parks, Eugene L. Stewart, Timothy M. Willson, Millard H. Lambert, John T. Moore, Kenneth H. Pearce, H. Eric Xu Hit paper breakdown →	2002	652
15	Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα Nature ·H. Eric Xu, Thomas B. Stanley, Valerie G. Montana, Millard H. Lambert, Barry G. Shearer, Jeffery E. Cobb, David D. McKee, Cristin M. Galardi, Kelli D. Plunket, Robert T. Nolte, Derek J. Parks, John T. Moore, Steven A. Kliewer, Timothy M. Willson, Julie B. Stimmel Hit paper breakdown →	2002	521
16	Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands Journal of Biological Chemistry ·Linda B. Moore, Derek J. Parks, Stacey A. Jones, Randy K. Bledsoe, Thomas G. Consler, Julie B. Stimmel, Bryan Goodwin, Christopher Liddle, Steven G. Blanchard, Timothy M. Willson, Jon L. Collins, Steven A. Kliewer Hit paper breakdown →	2000	684
17	Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors Molecular Cell ·H. Eric Xu, Millard H. Lambert, Valerie G. Montana, Derek J. Parks, Steven G. Blanchard, Peter J. Brown, Daniel D. Sternbach, Jürgen M. Lehmann, G. Bruce Wisely, Timothy M. Willson, Steven A. Kliewer, Michael V. Milburn Hit paper breakdown →	1999	938
18	Agouti Antagonism of Melanocortin Binding and Action in the B16F10 Murine Melanoma Cell Line Biochemistry ·Steven G. Blanchard, Cole O. Harris, Olivia Ittoop, James S. Nichols, Derek J. Parks, Anne T. Truesdale, William O. Wilkison	1995	60
19	A Fluorescence-Based Assay for Human Type II Phospholipase A2 Analytical Biochemistry ·Steven G. Blanchard, Cole O. Harris, Derek J. Parks	1994	20
20	Substrate Specificity in Short-Chain Phospholipid Analogs at the Active Site of Human Synovial Phospholipase A2 Journal of Medicinal Chemistry ·Thomas N. Wheeler, Steven G. Blanchard, Frank Fang, Yolanda Gray‐Nunez, Cole O. Harris, Millard H. Lambert, Mukund M. Mehrotra, Derek J. Parks, R. C. Andrew	1994	16

About Derek J. Parks

Derek J. Parks is a scholar working on Biochemistry, Pharmacology, Physiology, Oncology and Endocrine and Autonomic Systems, having authored 42 papers that have together received 9.5k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (15 papers), Estrogen and related hormone effects (11 papers), Cholesterol and Lipid Metabolism (10 papers), Peroxisome Proliferator-Activated Receptors (10 papers), Pharmacogenetics and Drug Metabolism (6 papers), Eicosanoids and Hypertension Pharmacology (5 papers), Adenosine and Purinergic Signaling (3 papers) and Retinoids in leukemia and cellular processes (3 papers). The work is most often cited by research in Pharmacology (1.3k citations), Oncology (3.5k citations), Biochemistry (636 citations), Endocrine and Autonomic Systems (554 citations) and Endocrinology, Diabetes and Metabolism (1.1k citations). Derek J. Parks has collaborated with scholars based in United States, Netherlands and United Kingdom. Frequent co-authors include Timothy M. Willson, Steven A. Kliewer, Steven G. Blanchard, Randy K. Bledsoe, Thomas G. Consler, Julie B. Stimmel, Jürgen M. Lehmann, Millard H. Lambert, Jon L. Collins and Gyan Chandra. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Biological Chemistry, Antimicrobial Agents and Chemotherapy and Analytical Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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