Michael A. Stashko

2.3k citations

51 papers · 1.5k indexed · h-index 23

Impact in

Toxicology top 2%
- Bioactive Compounds and Antitumor Agents
Immunology top 5%
- Phagocytosis and Immune Regulation
- Galectins and Cancer Biology

Papers in ⓘ

Immunology 26
- Phagocytosis and Immune Regulation 21
Toxicology 3

Co-authors: Stephen V. Frye (24 shared papers)Xiaodong Wang (25 shared papers)Dmitri Kireev (22 shared papers)James M. Trevillyan (6 shared papers)Thomas Lübben (6 shared papers)Douglas K. Graham (18 shared papers)Deborah DeRyckere (18 shared papers)H. Shelton Earp (17 shared papers)
Journals: Journal of Medicinal Chemistry (19 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)European Journal of Medicinal Chemistry (3 papers)SLAS DISCOVERY (2 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

Michael A. Stashko

46 papers receiving 1.5k citations

Peers

Countries citing papers authored by Michael A. Stashko

Since Specialization

Citations

This map shows the geographic impact of Michael A. Stashko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael A. Stashko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael A. Stashko more than expected).

Fields of papers citing papers by Michael A. Stashko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael A. Stashko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael A. Stashko. The network helps show where Michael A. Stashko may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael A. Stashko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael A. Stashko Line = papers co-authored together Michael A. Stashko links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 51 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy Journal of the American Chemical Society ·Bruce G. Szczepankiewicz, Gang Liu, Philip J. Hajduk, Cele Abad‐Zapatero, Zhonghua Pei, Zhili Xin, Thomas Lübben, James M. Trevillyan, Michael A. Stashko, Stephen J. Ballaron, Heng Liang, Flora Huang, Charles W. Hutchins, Stephen W. Fesik, Michael R. Jirousek	2003	185
2	UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor Journal of Medicinal Chemistry ·Weihe Zhang, Deborah DeRyckere, Debra M. Hunter, Jing Liu, Michael A. Stashko, Katherine A. Minson, Christopher T. Cummings, Minjung Lee, Trevor Glaros, Dianne L. Newton, Susan Sather, Dehui� Zhang, Dmitri Kireev, William P. Janzen, H. Shelton Earp, Douglas K. Graham, Stephen V. Frye, Xiaodong Wang	2014	118
3	Nonsteroidal Selective Glucocorticoid Modulators: the Effect of C-5 Alkyl Substitution on the Transcriptional Activation/Repression Profile of 2,5-Dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines Journal of Medicinal Chemistry ·Steven W. Elmore, Michael J. Coghlan, David D. Anderson, John K. Pratt, Brian E. Green, Alan X. Wang, Michael A. Stashko, Chun Wel Lin, Curtis M. Tyree, Jeffery N. Miner, Peer B. Jacobson, Denise M. Wilcox, Benjamin C. Lane	2001	94
4	Selective Protein Tyrosine Phosphatase 1B Inhibitors: Targeting the Second Phosphotyrosine Binding Site with Non-Carboxylic Acid-Containing Ligands Journal of Medicinal Chemistry ·Gang Liu, Zhili Xin, Heng Liang, Cele Abad‐Zapatero, Philip J. Hajduk, David A. Janowick, Bruce G. Szczepankiewicz, Zhonghua Pei, Charles W. Hutchins, Stephen J. Ballaron, Michael A. Stashko, Thomas Lübben, Cathy Berg, Cristina M. Rondinone, James M. Trevillyan, Michael R. Jirousek	2003	90
5	Nonsteroidal Selective Glucocorticoid Modulators: The Effect of C-10 Substitution on Receptor Selectivity and Functional Potency of 5-Allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines Journal of Medicinal Chemistry ·Philip R. Kym, Michael E. Kort, Michael J. Coghlan, J. L. MOORE, Rui Tang, James D. Ratajczyk, Daniel P. Larson, Steven W. Elmore, John K. Pratt, Michael A. Stashko, H. Douglass Falls, Chun Wel Lin, Masake Nakane, Loan Miller, Curtis M. Tyree, Jeffery N. Miner, Peer B. Jacobson, Denise M. Wilcox, Phong Nguyen, Benjamin C. Lane	2003	86
6	Synthesis and Characterization of Non-Steroidal Ligands for the Glucocorticoid Receptor: Selective Quinoline Derivatives with Prednisolone-Equivalent Functional Activity Journal of Medicinal Chemistry ·Michael J. Coghlan, Philip R. Kym, Steven W. Elmore, Alan X. Wang, Jay R. Luly, Denise Wilcox, Michael A. Stashko, Chun‐Wei Lin, Jeffrey N. Miner, Curtis M. Tyree, Masaki Nakane, Peer B. Jacobson, Benjamin C. Lane	2001	78
7	The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia JCI Insight ·Katherine A. Minson, Catherine C. Smith, Deborah DeRyckere, Clara Libbrecht, Alisa B. Lee‐Sherick, Madeline G. Huey, Elisabeth A. Lasater, Gregory D. Kirkpatrick, Michael A. Stashko, Weihe Zhang, Craig T. Jordan, Dmitri Kireev, Xiaodong Wang, Stephen V. Frye, H. Shelton Earp, Neil P. Shah, Douglas K. Graham	2016	61
8	The Lipid Kinase PIP5K1C Regulates Pain Signaling and Sensitization Neuron ·Brittany D. Wright, Lipin Loo, Sarah E. Street, Anqi Ma, Bonnie Taylor‐Blake, Michael A. Stashko, Jian Jin, William P. Janzen, Stephen V. Frye, Mark J. Zylka	2014	60
9	UNC1062, a new and potent Mer inhibitor European Journal of Medicinal Chemistry ·Jing Liu, Weihe Zhang, Michael A. Stashko, Deborah DeRyckere, Christopher T. Cummings, Debra M. Hunter, Chao Yang, Chatura N. Jayakody, Nancy Cheng, Catherine Simpson, Jacqueline Norris‐Drouin, Susan Sather, Dmitri Kireev, William P. Janzen, H. Shelton Earp, Douglas K. Graham, Stephen V. Frye, Xiaodong Wang	2013	55
10	Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors Journal of Medicinal Chemistry ·Weihe Zhang, Dehui� Zhang, Michael A. Stashko, Deborah DeRyckere, Debra M. Hunter, Dmitri Kireev, Michael J. Miley, Christopher T. Cummings, Minjung Lee, Jacqueline Norris‐Drouin, Wendy Stewart, Susan Sather, Yingqiu Zhou, Gregory Kirkpatrick, Mischa Machius, William P. Janzen, H. Shelton Earp, Douglas K. Graham, Stephen V. Frye, Xiaodong Wang	2013	55
11	Identification of a monoacid-Based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B Bioorganic & Medicinal Chemistry Letters ·Zhili Xin, Gang Liu, Cele Abad‐Zapatero, Zhonghua Pei, Bruce G. Szczepankiewicz, Xiaofeng Li, Tianyuan Zhang, Charles W. Hutchins, Philip J. Hajduk, Stephen J. Ballaron, Michael A. Stashko, Thomas Lübben, James M. Trevillyan, Michael R. Jirousek	2003	52
12	ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease. Journal of Pharmacology and Experimental Therapeutics ·Kazumi Shiosaki, Peter Jenner, Karen E. Asin, Donald R. Britton, C W Lin, Michael Michaelides, L. A. Smith, Benedetta Bianchi, Stanley DiDomenico, L. Mark Hodges, Yonggeun Hong, L C Mahan, Joseph P. Mikusa, Thomas R. Miller, Arthur L. Nikkel, Michael A. Stashko, Daniel R. Witte, Michael Williams	1996	52
13	Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators Bioorganic & Medicinal Chemistry Letters ·Steven W. Elmore, John K. Pratt, Michael J. Coghlan, Yue Mao, Brian E. Green, David D. Anderson, Michael A. Stashko, Chun Wel Lin, Douglas L. Falls, Masaki Nakane, Loan Miller, Curtis M. Tyree, Jeffrey N. Miner, Ben Lane	2004	41
14	Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis Journal of Medicinal Chemistry ·Weihe Zhang, Andrew L. McIver, Michael A. Stashko, Deborah DeRyckere, Brian R. Branchford, Debra M. Hunter, Dmitri Kireev, Michael J. Miley, Jacqueline Norris‐Drouin, Wendy Stewart, Minjung Lee, Susan Sather, Yingqiu Zhou, Jorge A. Di Paola, Mischa Machius, William P. Janzen, H. Shelton Earp, Douglas K. Graham, Stephen V. Frye, Xiaodong Wang	2013	40
15	Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure–Activity Analysis Journal of Medicinal Chemistry ·Chunfang Gu, Michael A. Stashko, Ana C. Puhl-Rubio, Molee Chakraborty, Anutosh Chakraborty, Stephen V. Frye, Kenneth H. Pearce, Xiaodong Wang, Stephen B. Shears, Huanchen Wang	2019	39
16	Characterization of cloned human dopamine D1 receptor-mediated calcium release in 293 cells. Molecular Pharmacology ·Chii‐Wann Lin, T. R. Miller, David G. Witte, Benedetta Bianchi, Michael A. Stashko, Arlene M. Manelli, D E Frail	1995	36
17	Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Oncotarget ·Alisa B. Lee‐Sherick, Weihe Zhang, Kelly Menachof, Amanda A. Hill, Sean Rinella, Gregory Kirkpatrick, Lauren S. Page, Michael A. Stashko, Craig T. Jordan, Qi Wei, Jing Liu, Dehui� Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen V. Frye, H. Shelton Earp, Douglas K. Graham	2015	35
18	Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636. Journal of Pharmacology and Experimental Therapeutics ·Chii‐Wann Lin, Benedetta Bianchi, T. R. Miller, Michael A. Stashko, Song Shung Wang, Peter Curzon, Lisa Bednarz, Karen E. Asin, Donald R. Britton	1996	33
19	Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors Biochemistry ·Kenton L. Longenecker, Kent D. Stewart, David J. Madar, Clarissa G. Jakob, Elizabeth H. Fry, Sherwin Wilk, Chun Wel Lin, Stephen J. Ballaron, Michael A. Stashko, Thomas Lübben, Hong Yong, Daisy Pireh, Zhonghua Pei, Fatima Z. Basha, Paul E. Wiedeman, Thomas W von Geldern, James M. Trevillyan, Vincent S. Stoll	2006	32
20	Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit Bioorganic & Medicinal Chemistry Letters ·Bradley J. Backes, Kenton L. Longenecker, Gregory L. Hamilton, Kent D. Stewart, Chunqiu Lai, Hana Kopecka, Thomas W von Geldern, David J. Madar, Zhonghua Pei, Thomas Lübben, Bradley A. Zinker, Zhenping Tian, Stephen J. Ballaron, Michael A. Stashko, Amanda K. Mika, David W. A. Beno, Anita J. Kempf-Grote, Candace Black‐Schaefer, Hing L. Sham, James M. Trevillyan	2007	31

About Michael A. Stashko

Michael A. Stashko is a scholar working on Immunology, Toxicology, Cellular and Molecular Neuroscience, Biological Psychiatry and Cell Biology, having authored 51 papers that have together received 1.5k indexed citations. Recurring topics across this work include Phagocytosis and Immune Regulation (21 papers), Receptor Mechanisms and Signaling (6 papers), Cancer Mechanisms and Therapy (5 papers), Estrogen and related hormone effects (5 papers), Computational Drug Discovery Methods (5 papers), Neuropeptides and Animal Physiology (5 papers), Protein Kinase Regulation and GTPase Signaling (5 papers) and Endoplasmic Reticulum Stress and Disease (4 papers). The work is most often cited by research in Toxicology (95 citations), Immunology (491 citations), Organic Chemistry (340 citations), Molecular Biology (708 citations) and Cellular and Molecular Neuroscience (166 citations). Michael A. Stashko has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Stephen V. Frye, Xiaodong Wang, Dmitri Kireev, James M. Trevillyan, Thomas Lübben, Douglas K. Graham, Deborah DeRyckere, H. Shelton Earp, Zhonghua Pei and William P. Janzen. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, European Journal of Medicinal Chemistry, SLAS DISCOVERY and Journal of Pharmacology and Experimental Therapeutics.

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