David D. McKee

10.5k citations

24 papers · 8.9k indexed · 6 hit papers · h-index 22

Pharmacology top 0.02%
- Pharmacogenetics and Drug Metabolism 6
Oncology top 0.5%
- Drug Transport and Resistance Mechanisms 5
Endocrinology, Diabetes and Metabolism top 0.5%
- Hormonal Regulation and Hypertension 5
Genetics top 0.5%
- Estrogen and related hormone effects 10
Molecular Biology top 2%
- Retinoids in leukemia and cellular processes 3
- Genomics and Chromatin Dynamics 2
Surgery
- Cholesterol and Lipid Metabolism 4
Organic Chemistry
- Ferrocene Chemistry and Applications 2

Co-authors: Timothy M. Willson Steven A. Kliewer John T. Moore Linda B. Moore Stacey A. Jones Millard H. Lambert J�rgen Lehmann M. A. Watson
Cited by: Pharmacology Oncology Endocrinology, Diabetes and Metabolism
Journals: Journal of Biological Chemistry (3 papers)Journal of Medicinal Chemistry (3 papers)Cell (2 papers)
Partner nations: United States Netherlands Sweden

In The Last Decade

David D. McKee

24 papers receiving 8.6k citations

Hit Papers

6 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2002 Cell
2002 Nature
2000 Molecular Cell
1998 Journal of Clinical Investigation
1998 Cell
1985 Journal of the American Chemical Society

Peers

Countries citing papers authored by David D. McKee

Since Specialization

Citations

This map shows the geographic impact of David D. McKee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David D. McKee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David D. McKee more than expected).

Fields of papers citing papers by David D. McKee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David D. McKee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David D. McKee. The network helps show where David D. McKee may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David D. McKee, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David D. McKee Line = papers co-authored together David D. McKee links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution Acta Crystallographica Section F Structural Biology Communications ·Kenneth H. Pearce,Laurie K. Overton,Robert T. Gampe,Sh. M. Rakhmatullaev,J. David Taylor,David D. McKee,Nino Campobasso,Robert T. Nolte,Robert A. Reid	2019	12
2	X-ray Crystal Structures of the Estrogen-related Receptor-γ Ligand Binding Domain in Three Functional States Reveal the Molecular Basis of Small Molecule Regulation Journal of Biological Chemistry ·Liping Wang,William J. Zuercher,Thomas G. Consler,Millard H. Lambert,Aaron B. Miller,Lisa A. Orband‐Miller,David D. McKee,Timothy M. Willson,Robert T. Nolte	2006	110
3	X-ray Crystal Structure of the Liver X Receptor β Ligand Binding Domain Journal of Biological Chemistry ·Shawn P. Williams,Randy K. Bledsoe,Jon L. Collins,Sharon Boggs,Millard H. Lambert,Ann B. Miller,John T. Moore,David D. McKee,Linda B. Moore,Jason A. Nichols,Derek J. Parks,Roser Mascaró Talaya,Bruce Wisely,Timothy M. Willson	2003	170
4	Williams, S. et al. X-ray crystal structure of the liver X receptor ligand binding domain: regulation by a histidine-tryptophan switch. J. Biol. Chem. 278, 27138-27143 Shawn P. Williams,Randy K. Bledsoe,Jon L. Collins,Sharon Boggs,Millard H. Lambert,Ann B. Miller,A.L. Caldeira-Brant,David D. McKee,Linda B. Moore,Jason A. Nichols,Derek J. Parks,Roser Mascaró Talaya,Bruce Wisely,Timothy M. Willson	2003	26
5	Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognitionbreakdown → Cell ·Randy K. Bledsoe,Valerie G. Montana,Thomas B. Stanley,Chris J. Delves,C.J. Apolito,David D. McKee,Thomas G. Consler,Derek J. Parks,Eugene L. Stewart,Timothy M. Willson,Millard H. Lambert,John T. Moore,Kenneth H. Pearce,H. Eric Xu	2002	652
6	Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARαbreakdown → Nature ·H. Eric Xu,Thomas B. Stanley,Valerie G. Montana,Millard H. Lambert,Barry G. Shearer,Jeffery E. Cobb,David D. McKee,Cristin M. Galardi,Kelli D. Plunket,Robert T. Nolte,Derek J. Parks,John T. Moore,Steven A. Kliewer,Timothy M. Willson,Julie B. Stimmel	2002	521
7	Pregnane X Receptor (PXR), Constitutive Androstane Receptor (CAR), and Benzoate X Receptor (BXR) Define Three Pharmacologically Distinct Classes of Nuclear Receptors Molecular Endocrinology ·Linda B. Moore,Jodi M. Maglich,David D. McKee,Bruce Wisely,Timothy M. Willson,Steven A. Kliewer,Millard H. Lambert,John T. Moore	2002	298
8	Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes Genome biology ·Jodi M. Maglich,Ann E. Sluder,Xiaojun Guan,Siqi Liu,David D. McKee,Kevin Carrick,Kim P Kamdar,Timothy M. Willson,John T. Moore	2001	203
9	Regulation of the Human CYP2B6 Gene by the Nuclear Pregnane X Receptor Molecular Pharmacology ·Bryan Goodwin,Linda B. Moore,Tomohiro Konishi,David D. McKee,Steven A. Kliewer	2001	302
10	Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors Proceedings of the National Academy of Sciences ·H. Eric Xu,Millard H. Lambert,Valerie G. Montana,Kelli D. Plunket,Linda B. Moore,Jon L. Collins,EN Kotey,Steven A. Kliewer,Robert T. Gampe,David D. McKee,John T. Moore,Timothy M. Willson	2001	449
11	Production and Characterization of an Estrogen Receptor β Subtype-Specific Mouse Monoclonal Antibody Hybridoma ·Jui‐Lan Su,David D. McKee,Byron Ellis,Sue H. Kadwell,G. Bruce Wisely,Linda B. Moore,O. P. Sivak,Thomas A. Kost,Suzanne A.W. Fuqua,John T. Moore	2000	7
12	A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesisbreakdown → Molecular Cell ·Bryan Goodwin,Stacey A. Jones,Russell Klopfer,Michael A. Watson,David D. McKee,Linda B. Moore,Cristin M. Galardi,Joan G. Wilson,Michael C. Lewis,Matthew E. Roth,Patrick Maloney,Timothy M. Willson,Steven A. Kliewer	2000	1598
13	Structure of the Tie2 RTK Domain Structure ·Lisa M. Shewchuk,Anne M. Hassell,Byron Ellis,William D. Holmes,袁菡苓,Kouadio Assohoun Tigoli Gildas,Sue H. Kadwell,David D. McKee,John T. Moore	2000	113
14	The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution Molecular Endocrinology ·Stacey A. Jones,Linda B. Moore,Tifani Anisa Putri,G. Bruce Wisely,Geraldine A. Hamilton,David D. McKee,Nicholas C. O. Tomkinson,Edward L. LeCluyse,Millard H. Lambert,Timothy M. Willson,Steven A. Kliewer,John T. Moore	2000	470
15	An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathwaybreakdown → Cell ·Steven A. Kliewer,John T. Moore,Hailu Amanuel,Jeff L. Staudinger,Mitchell Fisher,Stacey A. Jones,David D. McKee,محمد عز,Timothy M. Willson,Rolf Zetterström,Thomas Perlmann,Jürgen M. Lehmann	1998	1299
16	The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.breakdown → Journal of Clinical Investigation ·J�rgen Lehmann,David D. McKee,M. A. Watson,Timothy M. Willson,John T. Moore,Steven A. Kliewer	1998	1314
17	Cloning and Characterization of Human Estrogen Receptor β Isoforms Biochemical and Biophysical Research Communications ·John T. Moore,David D. McKee,Kimberly Slentz‐Kesler,Linda B. Moore,Stacey A. Jones,Kouadio Assohoun Tigoli Gildas,Ayling Ruth M,Steven A. Kliewer,Jürgen M. Lehmann,Timothy M. Willson	1998	437
18	2-[(Arylmethyl)amino]-2-methyl-1,3-propanediol DNA intercalators. An examination of the effects of aromatic ring variation on antitumor activity and DNA binding Journal of Medicinal Chemistry ·Kenneth W. Bair,C. Webster Andrews,Richard L. Tuttle,Asril Bahar,Michael Cory,David D. McKee	1991	46
19	[(1-Pyrenylmethyl)amino] alcohols, a new class of antitumor DNA intercalators. Discovery and initial amine side chain structure-activity studies Journal of Medicinal Chemistry ·Kenneth W. Bair,Richard L. Tuttle,V C Knick,Michael Cory,David D. McKee	1990	70
20	Design, synthesis, and DNA binding properties of bifunctional intercalators. Comparison of polymethylene and diphenyl ether chains connecting phenanthridinebreakdown → Journal of the American Chemical Society ·Michael Cory,David D. McKee,박동호 박유나,David W. Henry,Joseph A. Miller	1985	416

About David D. McKee

David D. McKee is a scholar working on Pharmacology, Endocrinology, Diabetes and Metabolism and Genetics, having authored 24 papers that have together received 8.9k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (10 papers), Pharmacogenetics and Drug Metabolism (6 papers), Drug Transport and Resistance Mechanisms (5 papers), Hormonal Regulation and Hypertension (5 papers), Cholesterol and Lipid Metabolism (4 papers), Retinoids in leukemia and cellular processes (3 papers), Ferrocene Chemistry and Applications (2 papers) and Genomics and Chromatin Dynamics (2 papers). The work is most often cited by research in Pharmacology (2.8k citations), Oncology (3.8k citations) and Endocrinology, Diabetes and Metabolism (1.7k citations). David D. McKee has collaborated with scholars based in United States, Netherlands and Sweden. Frequent co-authors include Timothy M. Willson, Steven A. Kliewer, John T. Moore, Linda B. Moore, Stacey A. Jones, Millard H. Lambert, J�rgen Lehmann, M. A. Watson, Bryan Goodwin and Cristin M. Galardi. Their work appears in journals such as Journal of Biological Chemistry, Journal of Medicinal Chemistry, Cell, Molecular Endocrinology and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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