Frank Lovering

7.1k citations

28 papers · 5.2k indexed · 2 hit papers · h-index 19

Organic Chemistry top 0.2%
Molecular Biology top 5%
Computational Theory and Mathematics top 1%
Inorganic Chemistry top 2%
Pharmaceutical Science top 0.5%

Co-authors: Christine Humblet Jack Bikker William H. Pearson R. Aldrin Denny Ray Unwalla A. Richard Chamberlin Richard J. Bridges Xing Li
Topics: Computational Drug Discovery Methods (7 papers)Chemical Synthesis and Analysis (6 papers)Protein Kinase Regulation and GTPase Signaling (6 papers)
Cited by: Organic Chemistry Pharmaceutical Science Inorganic Chemistry
Journals: Journal of the American Chemical Society Scientific Reports Journal of Medicinal Chemistry
Partner nations: United States United Kingdom Canada

In The Last Decade

Frank Lovering

28 papers receiving 5.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

2009 3.2k citations Frank Lovering et al. Journal of Medicinal Chemistry profile →
Escape from Flatland 2: complexity and promiscuity

2012 1.1k citations Frank Lovering profile →

Peers

Countries citing papers authored by Frank Lovering

Since Specialization

Citations

This map shows the geographic impact of Frank Lovering's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Lovering with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Lovering more than expected).

Fields of papers citing papers by Frank Lovering

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Lovering. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Lovering. The network helps show where Frank Lovering may publish in the future.

Co-authorship network of co-authors of Frank Lovering

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Lovering. A scholar is included among the top collaborators of Frank Lovering based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Lovering. Frank Lovering is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Millisecond dynamics of BTK reveal kinome-wide conformational plasticity within the apo kinase domain 2017 ·Scientific Reports ·Mohammad M. Sultan,R. Aldrin Denny,Ray Unwalla,Frank Lovering,Vijay S. Pande	38
2	Fluorine in Drug Design: A Case Study with Fluoroanisoles 2015 ·ChemMedChem ·Xing Li,David C. Blakemore,Arjun Narayanan,Ray Unwalla,Frank Lovering,R. Aldrin Denny,Huanyu Zhou,Mark E. Bunnage	122
3	Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free‐Energy Perturbation (FEP) 2015 ·ChemMedChem ·Frank Lovering,(unknown),Jeanne S. Chang,Christoph M. Dehnhardt,Lori Fitz,Seungil Han,Kristin Janz,Julie Lee,Neelu Kaila,Joseph J. McDonald,William Moore,Alessandro Moretto,Νικόλαος Παπαϊωάννου,David J. Richard,Mark Ryan,Zhao‐Kui Wan,Atli Thorarensen	35
4	Identification of Type‐II Inhibitors Using Kinase Structures 2012 ·Chemical Biology & Drug Design ·Frank Lovering,Joseph J. McDonald,Gavin A. Whitlock,Paul A. Glossop,Chris Phillips,Andrew F. Bent,Yogesh Sabnis,Mark Ryan,Lori Fitz,Julie Lee,Jeanne S. Chang,Seungil Han,Ravi G. Kurumbail,Atli Thorarensen	17
5	Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Michael S. Malamas,Keith D. Barnes,Hui Yu,Matthew R. Johnson,Frank Lovering,(unknown),William F. Fobare,(unknown),Jim Turner,Yun Hu,Eric S. Manas,Kristi Fan,Andrea Olland,Rajiv Chopra,Jonathan Bard,Menelas N. Pangalos,Peter H. Reinhart,Albert J. Robichaud	30
6	Synthesis and activity of quinolinylmethyl P1′ α-sulfone piperidine hydroxamate inhibitors of TACE 2009 ·Bioorganic & Medicinal Chemistry Letters ·Chunchun Zhang,Frank Lovering,Mark L. Behnke,Arie Zask,Vincent Sandanayaka,Linhong Sun,Yi Zhun Zhu,Weixin Xu,Yuhua Zhang,Jeremy I. Levin	8
7	Structure-based design of TACE selective inhibitors: Manipulations in the S1′–S3′ pocket 2007 ·Bioorganic & Medicinal Chemistry ·Adrian Huang,Diane Joseph‐McCarthy,Frank Lovering,Linhong Sun,Weiheng Wang,Weixin Xu,Yi Zhun Zhu,Junqing Cui,Yuhua Zhang,Jeremy I. Levin	24
8	Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α₂α 2007 ·Journal of Medicinal Chemistry ·Katherine L. Lee,Megan A. Foley,Lih-Ren Chen,Mark L. Behnke,Frank Lovering,Steven J. Kirincich,Weiheng Wang,Jaechul Shim,Steve Tam,Marina W. H. Shen,(unknown),Xin Xu,Debra G. Goodwin,Manjunath Ramarao,Cheryl Nickerson‐Nutter,(unknown),(unknown),James D. Clark,John C. McKew	69
9	Design and synthesis of 3,3-piperidine hydroxamate analogs as selective TACE inhibitors 2007 ·Bioorganic & Medicinal Chemistry Letters ·Henry‐Georges Lombart,Eric Feyfant,Diane Joseph‐McCarthy,Adrian Huang,Frank Lovering,Linhong Sun,Yi Zhun Zhu,(unknown),Yuhua Zhang,Jeremy I. Levin	12
10	Identification of potent and selective TACE inhibitors via the S1 pocket 2006 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Diane Joseph‐McCarthy,Jeremy I. Levin,Henry‐Georges Lombart,Frank Lovering,Linhong Sun,Weiheng Wang,Weixin Xu,Yuhua Zhang	34
11	Inhibition of Cytosolic Phospholipase A 2 α: Hit to Lead Optimization 2006 ·John C. McKew,Megan A. Foley,Paresh Thakker,Mark L. Behnke,Frank Lovering,Fuk‐Wah Sum,Steve Tam,Kun Wu,Marina W. H. Shen,Wen Zhang,Mario D. González,Shanghao Liu,Anu Mahadevan,Howard Sard,(unknown),James D. Clark	10
12	A novel approach to identifying β-secretase inhibitors: Bis-statine peptide mimetics discovered using structure and spot synthesis 2006 ·Peptides ·Kristie Grove Bridges,Rajiv Chopra,Laura Lin,Kristine Svenson,Amy Tam,Guixian Jin,Rebecca Cowling,Frank Lovering,Tatos Akopian,Elizabeth A. DiBlasio-Smith,(unknown),(unknown),Edward R. LaVallie,Richard Zollner,Jonathan Bard,W.S. Somers,Mark Stahl,Ronald Kriz	6
13	Therapeutic Potential of TACE Inhibitors in Stroke 2005 ·PubMed ·Frank Lovering,(unknown)	37
14	Use of Structure-Based Drug Design Approaches to Obtain Novel Anthranilic Acid Acyl Carrier Protein Synthase Inhibitors 2005 ·Journal of Medicinal Chemistry ·Diane Joseph‐McCarthy,Kevin Parris,Adrian Huang,Amedeo Failli,Dominick Quagliato,(unknown),(unknown),Elena Severina,Margareta Tuckman,Peter J. Petersen,Charles R. Dean,Christian Fritz,Tova Meshulam,Maureen T. DeCenzo,Lawrence R. Dick,Iain J. McFadyen,W.S. Somers,Frank Lovering,A. Gilbert	27
15	Identification of potent and selective MMP-13 inhibitors 2005 ·Bioorganic & Medicinal Chemistry Letters ·Junjun Wu,Thomas S. Rush,Rajeev Hotchandani,Xuemei Du,Mary Geck,(unknown),Zhang‐Bao Xu,J.S. Skotnicki,Jeremy I. Levin,Frank Lovering	60
16	Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors 2004 ·Bioorganic & Medicinal Chemistry Letters ·Baihua Hu,Kristi Fan,Kristie Grove Bridges,Rajiv Chopra,Frank Lovering,Derek C. Cole,Ping Zhou,John W. Ellingboe,(unknown),Rebecca Cowling,Jonathan Bard	18
17	Structure–activity relationships of indole cytosolic phospholipase A 2 α inhibitors: substrate mimetics 2003 ·Bioorganic & Medicinal Chemistry Letters ·John C. McKew,Frank Lovering,James D. Clark,Jean E. Bemis,Yibin Xiang,Marina W. H. Shen,Wen Zhang,Juan Carlos Álvarez,Diane Joseph‐McCarthy	18
18	Assembly of 3a-Arylperhydroindoles by the Intramolecular Cycloaddition of 2-Azaallyl Anions with Alkenes. Total Syntheses of (±)-Crinine, (±)-6-Epicrinine, (−)-Amabiline, and (−)-Augustamine 1998 ·The Journal of Organic Chemistry ·William H. Pearson,Frank Lovering	42
19	A Selective Photoaffinity Ligand for the Kainate Class of Excitatory Amino Acid Receptor 1997 ·Synlett ·Dean A. Wacker,Frank Lovering,Richard J. Bridges,Colin L. Willis,Richard D. Bartlett,A. Richard Chamberlin	2
20	A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: l-anti-endo-3,4-methanopyrrolidine dicarboxylate 1994 ·Neuroscience Letters ·Richard J. Bridges,Frank Lovering,Hans P. Koch,Carl W. Cotman,A. Richard Chamberlin	42

About Frank Lovering

Frank Lovering is a scholar working on Immunology and Allergy, Pharmacology and Computational Theory and Mathematics, having authored 28 papers that have together received 5.2k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (7 papers), Chemical Synthesis and Analysis (6 papers) and Protein Kinase Regulation and GTPase Signaling (6 papers). The work is most often cited by research in Organic Chemistry (3.7k citations), Pharmaceutical Science (482 citations) and Inorganic Chemistry (560 citations). Frank Lovering has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Christine Humblet, Jack Bikker, William H. Pearson, R. Aldrin Denny, Ray Unwalla, A. Richard Chamberlin, Richard J. Bridges, Xing Li, Huanyu Zhou and Mark E. Bunnage. Their work appears in journals such as Journal of the American Chemical Society, Scientific Reports and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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