Seungil Han

5.7k citations

50 papers · 2.8k indexed · h-index 27

Impact in

Sensory Systems top 2%
- Ion Channels and Receptors
Molecular Medicine top 2%
- Antibiotic Resistance in Bacteria

Papers in

Molecular Medicine 5
- Antibiotic Resistance in Bacteria 5
Physiology 4
- Calcium signaling and nucleotide metabolism 4

Co-authors: John A. Tainer Lindsay D. Eltis Jeffrey T. Bolin Kenneth N. Timmis Steven W. Muchmore A.S. Arvai Christopher D. Putnam Nadine B. Carozzi
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Biological Chemistry (5 papers)Nature Communications (3 papers)Nature Structural & Molecular Biology (3 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United States United Kingdom Switzerland

In The Last Decade

Seungil Han

50 papers receiving 2.7k citations

Peers

Countries citing papers authored by Seungil Han

Since Specialization

Citations

This map shows the geographic impact of Seungil Han's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seungil Han with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seungil Han more than expected).

Fields of papers citing papers by Seungil Han

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seungil Han. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seungil Han. The network helps show where Seungil Han may publish in the future.

Co-authors

The 25 scholars most cited alongside Seungil Han, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seungil Han Line = papers co-authored together Seungil Han links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cyclosporine A sterically inhibits statin transport by solute carrier OATP1B1 Journal of Biological Chemistry ·Min Woo Sung, H.J. Fiβan, Lea M. Hürlimann, Joshua A. Lees, Kimberly F. Fennell, Mark A. West, Chester Costales, A. David Rodrigues, Iwan Zimmermann, Roger Dawson, Shenping Liu, Seungil Han	2025	2
2	In Retrospect: Root-Cause Analysis of Structure–Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833) ACS Medicinal Chemistry Letters ·Stephen W. Wright, Kathleen A. Farley, Seungil Han, John D. Knafels, Katherine L. Lee	2024	2
3	Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1 Nucleic Acids Research ·Hallikainen Anja, Min Woo Sung, Shridhar Bhat, Yingrong Xu, Kevin W. Huynh, Seungil Han, Darren C. Johnson, Benedikt Bosbach, David J. Shields, James T. Stivers	2023	2
4	Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics Nucleic Acids Research ·Hallikainen Anja, Kevin W. Huynh, Mark Ammirati, Seungil Han, Ben Bolaños, Richard J. Chavez, Matthew D. Petroski, Benedikt Bosbach, David J. Shields, James T. Stivers	2022	8
5	Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate Nature Structural & Molecular Biology ·Thomas J. McCorvie, Paula M. Loria, Meihua Tu, Seungil Han, Leela Shrestha, D. Sean Froese, Igor Monteze Ferreira, Allison P. Berg, Wyatt W. Yue	2022	17
6	Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion Science Advances ·Yuhang Liu, Kyle P. Heim, Ye Che, C. Villalobos-Ojeda, Xiayang Qiu, Seungil Han, Philip R. Dormitzer, Xinzhen Yang	2021	62
7	Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease Journal of Lipid Research ·Francis Rajamohan, Allan R. Reyes, Meihua Tu, Setia Lestari Pane, Lise R. Hoth, Adam G. Schwaid, Ravi G. Kurumbail, Jessica Ward, Seungil Han	2020	11
8	Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins Nature Communications ·Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances Joan D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, 阿部広喜, Mahshid Eltemasi, John S. Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff	2020	67
9	Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20 Nature Communications ·JG Mackenzie, Z.L. Johnson, Mark Ammirati, Ye Che, Matthew C. Griffor, Seungil Han, Huixian Wu	2020	69
10	Development of a high-throughput crystal structure-determination platform for JAK1 using a novel metal-chelator soaking system Acta Crystallographica Section F Structural Biology Communications ·Nicole Caspers, Seungil Han, Francis Rajamohan, Lise R. Hoth, Kieran F. Geoghegan, Timothy A. Subashi, Michael L. Vazquez, Neelu Kaila, Ciarán N. Cronin, Eric F. Johnson, Ravi G. Kurumbail	2016	6
11	Expression and functional characterization of human lysosomal acid lipase gene (LIPA) mutation responsible for cholesteryl ester storage disease (CESD) phenotype Protein Expression and Purification ·Francis Rajamohan, Allan R. Reyes, J. P. Atkinson, Lise R. Hoth, Seungil Han, Nicole Caspers, Meihua Tu, Jessica Ward, Ravi G. Kurumbail	2015	11
12	Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates Bioorganic & Medicinal Chemistry Letters ·Thomas V. Magee, Seungil Han, Sandra P. McCurdy, Clementine Oliver, Alfredo Estrada, Eric S. Marr, Bruce A. Maguire, Michael D. Huband, Jinshan Michael Chen, Timothy A. Subashi, Veerabahu Shanmugasundaram	2013	18
13	Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin Protein Engineering Design and Selection ·Katarina S. Midelfort, Zexiang Xu, Seungil Han, Michael J. Karmilowicz, Kang Chunmin, Daniel K. Gehlhaar, Laboratorio Tecnológico del Uruguay, Jo‐Shu Chang, Mary E. Anderson, Anderson Manuel Valoyes Olier, Jeremy Minshull, Subbiah Govindarajan, Anis Abdallah	2012	112
14	Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region Bioorganic & Medicinal Chemistry Letters ·Robert Hughes, Todd M. Maddux, D. Joseph Rogier, Sharon Lu, John K. Walker, E. Jon Jacobsen, Jeanne M. Rumsey, Zhiquan Ai, Mona M. Almramhi, Brian R. Bond, Seungil Han	2011	12
15	Crystal Structure of Activin Receptor Type IIB Kinase Domain Vitamins and hormones ·Seungil Han	2011	5
16	A systematic study of 50S ribosomal subunit purification enabling robust crystallization Acta Crystallographica Section D Biological Crystallography ·Thomas J. McLellan, Eric S. Marr, L Wondrack, Timothy A. Subashi, Paul A. Aeed, Seungil Han, Won‐Wu Lee, Ing-Kae Wang, Bruce A. Maguire	2009	14
17	Structure of the adenylation domain of NAD⁺-dependent DNA ligase fromStaphylococcus aureus Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Seungil Han, Jeanne S. Chang, Matt Griffor	2009	9
18	Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design Journal of Biological Chemistry ·Seungil Han, Anil Mistry, Jeanne S. Chang, David Cunningham, Matt Griffor, Peter C. Bonnette, Hong Wang, Boris A. Chrunyk, Gary E. Aspnes, Daniel P. Walker, Nuray ÖZTÜRK, Leonard Buckbinder	2009	86
19	Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Å resolution Protein Science ·Seungil Han, モリスマーティン, Matt Griffor, Zhi Xie	2007	25
20	The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases International Journal of Medical Microbiology ·Seungil Han, John A. Tainer	2001	76

About Seungil Han

Seungil Han is a scholar working on Molecular Medicine, Physiology, Sensory Systems, Structural Biology and Molecular Biology, having authored 50 papers that have together received 2.8k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (6 papers), Monoclonal and Polyclonal Antibodies Research (6 papers), Antibiotic Resistance in Bacteria (5 papers), RNA and protein synthesis mechanisms (4 papers), Calcium signaling and nucleotide metabolism (4 papers), Ion Channels and Receptors (4 papers), Bacterial Genetics and Biotechnology (4 papers) and Toxin Mechanisms and Immunotoxins (4 papers). The work is most often cited by research in Sensory Systems (187 citations), Molecular Medicine (185 citations), Physiology (109 citations), Molecular Biology (1.6k citations) and Inorganic Chemistry (237 citations). Seungil Han has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include John A. Tainer, Lindsay D. Eltis, Jeffrey T. Bolin, Kenneth N. Timmis, Steven W. Muchmore, A.S. Arvai, Christopher D. Putnam, Nadine B. Carozzi, Junzhuan Qiu and B.R. Chapados. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry, Nature Communications, Nature Structural & Molecular Biology and Journal of Medicinal Chemistry.

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