Ravi G. Kurumbail

7.0k total citations · 2 hit papers
54 papers, 4.9k citations indexed

About

Ravi G. Kurumbail is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Ravi G. Kurumbail has authored 54 papers receiving a total of 4.9k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 18 papers in Organic Chemistry and 14 papers in Pharmacology. Recurrent topics in Ravi G. Kurumbail's work include Inflammatory mediators and NSAID effects (13 papers), Estrogen and related hormone effects (9 papers) and Blood Coagulation and Thrombosis Mechanisms (8 papers). Ravi G. Kurumbail is often cited by papers focused on Inflammatory mediators and NSAID effects (13 papers), Estrogen and related hormone effects (9 papers) and Blood Coagulation and Thrombosis Mechanisms (8 papers). Ravi G. Kurumbail collaborates with scholars based in United States, United Kingdom and China. Ravi G. Kurumbail's co-authors include William C. Stallings, Roderick A. Stegeman, Anna M. Stevens, James K. Gierse, Karen Seibert, Peter C. Isakson, Joseph J. McDonald, Thomas D. Penning, J. Deisenhofer and Charles A. Hasemann and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Biochemistry.

In The Last Decade

Ravi G. Kurumbail

54 papers receiving 4.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1996 1.6k citations Ravi G. Kurumbail, Anna M. Stevens et al. Nature profile →
Structure and function of cytochromes P450:a comparative analysis of three crystal structures

1995 584 citations Charles A. Hasemann, Ravi G. Kurumbail et al. Structure profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ravi G. Kurumbail United States	28	1.9k	1.8k	1.8k	719	667	54	4.9k
Philip M. Potter United States	50	2.0k 1.0×	3.5k 1.9×	761 0.4×	1.1k 1.6×	674 1.0×	128	6.3k
James K. Gierse United States	29	2.5k 1.3×	1.5k 0.8×	1.4k 0.8×	318 0.4×	414 0.6×	50	4.6k
Andreas Koeberle Germany	41	1.6k 0.8×	1.8k 1.0×	832 0.5×	273 0.4×	313 0.5×	134	4.5k
Michael G. Malkowski United States	33	1.1k 0.6×	1.4k 0.8×	630 0.4×	263 0.4×	255 0.4×	75	3.5k
Joseph J. McDonald United States	20	1.4k 0.8×	911 0.5×	1.1k 0.6×	388 0.5×	199 0.3×	38	2.9k
James L. Maggs United Kingdom	40	698 0.4×	1.1k 0.6×	717 0.4×	592 0.8×	1.5k 2.2×	109	4.5k
Carol M. Koboldt United States	24	2.3k 1.2×	767 0.4×	1.8k 1.0×	271 0.4×	301 0.5×	36	4.1k
Marco Macchia Italy	36	888 0.5×	2.1k 1.1×	1.2k 0.7×	395 0.5×	123 0.2×	226	4.3k
Thomas D. Penning United States	24	1.2k 0.6×	1.2k 0.7×	1.5k 0.9×	246 0.3×	178 0.3×	52	3.4k
Neil R. Kitteringham United Kingdom	47	819 0.4×	3.1k 1.7×	623 0.4×	294 0.4×	1.8k 2.8×	92	7.3k

Countries citing papers authored by Ravi G. Kurumbail

Since Specialization

Citations

This map shows the geographic impact of Ravi G. Kurumbail's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ravi G. Kurumbail with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ravi G. Kurumbail more than expected).

Fields of papers citing papers by Ravi G. Kurumbail

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ravi G. Kurumbail. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ravi G. Kurumbail. The network helps show where Ravi G. Kurumbail may publish in the future.

Co-authorship network of co-authors of Ravi G. Kurumbail

This figure shows the co-authorship network connecting the top 25 collaborators of Ravi G. Kurumbail. A scholar is included among the top collaborators of Ravi G. Kurumbail based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ravi G. Kurumbail. Ravi G. Kurumbail is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ryder, Tim F., Matthew F. Calabrese, Gregory S. Walker, et al.. (2018). Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H -indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK). Journal of Medicinal Chemistry. 61(16). 7273–7288. 18 indexed citations

Kurumbail, Ravi G., Graham M. West, Venkatasubramanian Dharmarajan, et al.. (2018). Biophysical Interactions of Direct AMPK Activators. Methods in molecular biology. 1732. 29–55. 1 indexed citations

Caspers, Nicole, Seungil Han, Francis Rajamohan, et al.. (2016). Development of a high-throughput crystal structure-determination platform for JAK1 using a novel metal-chelator soaking system. Acta Crystallographica Section F Structural Biology Communications. 72(11). 840–845. 6 indexed citations

Kurumbail, Ravi G. & Matthew F. Calabrese. (2016). Structure and Regulation of AMPK. Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions. 107. 3–22. 39 indexed citations

Rajamohan, Francis, Allan R. Reyes, Richard K. Frisbie, et al.. (2015). Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators. Biochemical Journal. 473(5). 581–592. 54 indexed citations

Rajamohan, Francis, Allan R. Reyes, Lise R. Hoth, et al.. (2015). Expression and functional characterization of human lysosomal acid lipase gene (LIPA) mutation responsible for cholesteryl ester storage disease (CESD) phenotype. Protein Expression and Purification. 110. 22–29. 11 indexed citations

Henderson, Jaclyn L., Bethany L. Kormos, Matthew M. Hayward, et al.. (2014). Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor. Journal of Medicinal Chemistry. 58(1). 419–432. 140 indexed citations

Landgraf, Rachelle R., Devrishi Goswami, Francis Rajamohan, et al.. (2013). Activation of AMP-Activated Protein Kinase Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry. Structure. 21(11). 1942–1953. 34 indexed citations

Kim, Kyung‐Hee, Andreas Maderna, Mark E. Schnute, et al.. (2011). Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis. Bioorganic & Medicinal Chemistry Letters. 21(21). 6258–6263. 48 indexed citations

10.

Rajamohan, Francis, Melissa S. Harris, Richard K. Frisbie, et al.. (2010). Escherichia coli expression, purification and characterization of functional full-length recombinant α2β2γ3 heterotrimeric complex of human AMP-activated protein kinase. Protein Expression and Purification. 73(2). 189–197. 21 indexed citations

11.

Anderson, David R., Marvin J. Meyers, Ravi G. Kurumbail, et al.. (2009). Benzothiophene inhibitors of MK2. Part 2: Improvements in kinase selectivity and cell potency. Bioorganic & Medicinal Chemistry Letters. 19(16). 4882–4884. 37 indexed citations

12.

Li, Xing, Ravi G. Kurumbail, Ronald B. Frazier, et al.. (2008). Homo-timeric structural model of human microsomal prostaglandin E synthase-1 and characterization of its substrate/inhibitor binding interactions. Journal of Computer-Aided Molecular Design. 23(1). 13–24. 16 indexed citations

13.

Schweitzer, Barbara A., William L. Neumann, Gennadiy Poda, et al.. (2005). Structure-based design and synthesis of pyrazinones containing novel P1 ‘side pocket’ moieties as inhibitors of TF/VIIa. Bioorganic & Medicinal Chemistry Letters. 15(12). 3006–3011. 13 indexed citations

14.

Parlow, John J., Ravi G. Kurumbail, Roderick A. Stegeman, et al.. (2003). Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex. Bioorganic & Medicinal Chemistry Letters. 13(21). 3721–3725. 19 indexed citations

15.

Rowlinson, Scott W., James R. Kiefer, Jeffery J. Prusakiewicz, et al.. (2003). A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385. Journal of Biological Chemistry. 278(46). 45763–45769. 282 indexed citations

16.

Kiefer, James R., Jennifer L. Pawlitz, Kirby T. Moreland, et al.. (2000). Structural insights into the stereochemistry of the cyclooxygenase reaction. Nature. 405(6782). 97–101. 212 indexed citations

17.

Cook, Bernard, Amy E. Rudolph, Ravi G. Kurumbail, Rhonda Porche-Sorbet, & Joseph P. Miletich. (2000). Directed Glycosylation of Human Coagulation Factor X at Residue 333. Journal of Biological Chemistry. 275(49). 38774–38779. 8 indexed citations

18.

Skrzypczak‐Jankun, Ewa & Ravi G. Kurumbail. (1996). 1-Trityl-4-nitroimidazole. Acta Crystallographica Section C Crystal Structure Communications. 52(1). 189–191. 2 indexed citations

19.

Kurumbail, Ravi G., Anna M. Stevens, James K. Gierse, et al.. (1996). Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature. 384(6610). 644–648. 1559 indexed citations breakdown →

20.

Istvan, Eva S., Charles A. Hasemann, Ravi G. Kurumbail, Kosaku Uyeda, & J. Deisenhofer. (1995). Crystallization and preliminary X‐ray analysis of fructose 6‐phosphate, 2‐kinase:fructose 2,6‐bisphosphatase. Protein Science. 4(11). 2439–2441. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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