Jack Bikker

5.0k total citations · 1 hit paper
18 papers, 3.8k citations indexed

About

Jack Bikker is a scholar working on Molecular Biology, Computational Theory and Mathematics and Organic Chemistry. According to data from OpenAlex, Jack Bikker has authored 18 papers receiving a total of 3.8k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 5 papers in Computational Theory and Mathematics and 4 papers in Organic Chemistry. Recurrent topics in Jack Bikker's work include Computational Drug Discovery Methods (5 papers), Synthesis and Reactivity of Heterocycles (3 papers) and Receptor Mechanisms and Signaling (3 papers). Jack Bikker is often cited by papers focused on Computational Drug Discovery Methods (5 papers), Synthesis and Reactivity of Heterocycles (3 papers) and Receptor Mechanisms and Signaling (3 papers). Jack Bikker collaborates with scholars based in United States, Canada and United Kingdom. Jack Bikker's co-authors include Christine Humblet, Frank Lovering, Susanne Trumpp-Kallmeyer, Natasja Brooijmans, Allan Wissner, Tarek S. Mansour, David C. Horwell, Donald F. Weaver, Nirmala Suman‐Chauhan and Victor J. Hruby and has published in prestigious journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry and Molecular Pharmacology.

In The Last Decade

Jack Bikker

18 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

2009 3.2k citations Frank Lovering, Jack Bikker et al. Journal of Medicinal Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jack Bikker United States	12	2.6k	1.3k	490	380	272	18	3.8k
Frank Lovering United States	19	3.7k 1.4×	1.6k 1.3×	603 1.2×	560 1.5×	380 1.4×	28	5.2k
David C. Rees United Kingdom	15	1.5k 0.6×	1.2k 0.9×	507 1.0×	223 0.6×	180 0.7×	16	3.1k
Antonia F. Stepan United States	20	1.7k 0.6×	733 0.6×	308 0.6×	271 0.7×	224 0.8×	37	2.9k
Christopher J. Helal United States	23	2.3k 0.9×	1.1k 0.9×	195 0.4×	889 2.3×	344 1.3×	36	3.4k
Sylvain Rault France	38	3.7k 1.4×	1.9k 1.5×	302 0.6×	148 0.4×	451 1.7×	296	5.2k
Rodolfo Lavilla Spain	31	3.2k 1.2×	1.3k 1.1×	219 0.4×	232 0.6×	514 1.9×	109	4.0k
William J. Greenlee United States	34	2.0k 0.7×	2.2k 1.8×	429 0.9×	141 0.4×	338 1.2×	161	4.5k
Frank M. Boeckler Germany	30	1.2k 0.5×	1.8k 1.5×	692 1.4×	395 1.0×	204 0.8×	75	3.6k
Paul Helquist United States	37	3.2k 1.2×	1.6k 1.3×	166 0.3×	840 2.2×	253 0.9×	169	4.9k
John W. Clader United States	28	1.4k 0.5×	953 0.8×	230 0.5×	118 0.3×	203 0.7×	72	3.1k

Countries citing papers authored by Jack Bikker

Since Specialization

Citations

This map shows the geographic impact of Jack Bikker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jack Bikker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jack Bikker more than expected).

Fields of papers citing papers by Jack Bikker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jack Bikker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jack Bikker. The network helps show where Jack Bikker may publish in the future.

Co-authorship network of co-authors of Jack Bikker

This figure shows the co-authorship network connecting the top 25 collaborators of Jack Bikker. A scholar is included among the top collaborators of Jack Bikker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jack Bikker. Jack Bikker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Irwin, Benedict, Dmitriy S. Chekmarev, Shyam Vyas, et al.. (2021). Imputation of sensory properties using deep learning. Journal of Computer-Aided Molecular Design. 35(11). 1125–1140. 6 indexed citations

Tumey, L. Nathan, Fengping Li, Brian Rago, et al.. (2017). Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates. The AAPS Journal. 19(4). 1123–1135. 48 indexed citations

Gilbert, A., Jack Bikker, & Steven V. O’Neil. (2010). Advances in the development of novel aggrecanase inhibitors. Expert Opinion on Therapeutic Patents. 21(1). 1–12. 24 indexed citations

Hu, Yongbo, Ray Unwalla, R. Aldrin Denny, et al.. (2009). Development of QSAR models for microsomal stability: identification of good and bad structural features for rat, human and mouse microsomal stability. Journal of Computer-Aided Molecular Design. 24(1). 23–35. 36 indexed citations

Brooijmans, Natasja, Dominick Mobilio, Gary Walker, et al.. (2009). A structural informatics approach to mine kinase knowledge bases. Drug Discovery Today. 15(5-6). 203–209. 7 indexed citations

Lovering, Frank, Jack Bikker, & Christine Humblet. (2009). Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success. Journal of Medicinal Chemistry. 52(21). 6752–6756. 3242 indexed citations breakdown →

Hayward, Matthew M., Jack Bikker, John W. Ellingboe, et al.. (2009). Lead-Seeking Approaches. Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)). 4 indexed citations

Bikker, Jack, Natasja Brooijmans, Allan Wissner, & Tarek S. Mansour. (2009). Kinase Domain Mutations in Cancer: Implications for Small Molecule Drug Design Strategies. Journal of Medicinal Chemistry. 52(6). 1493–1509. 136 indexed citations

Dounay, Amy B., Nancy S. Barta, Jack Bikker, et al.. (2008). Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT1A partial agonists. Bioorganic & Medicinal Chemistry Letters. 19(4). 1159–1163. 10 indexed citations

10.

Shim, Jaechul, et al.. (2008). Direct Oxa-Pictet−Spengler Cyclization to the Natural (3a,5)-trans-Stereochemistry in the Syntheses of (+)-7-Deoxyfrenolicin B and (+)-7-Deoxykalafungin. The Journal of Organic Chemistry. 74(1). 423–426. 35 indexed citations

11.

Bikker, Jack, et al.. (2000). Design and biological evaluation of non-peptide analogues of omega-conotoxin MVIIA. Bioorganic & Medicinal Chemistry Letters. 10(4). 345–347. 39 indexed citations

12.

Bikker, Jack, et al.. (1998). Synthesis of a non-peptide analogue of omega-conotoxin MVIIA. Tetrahedron Letters. 39(41). 7619–7622. 24 indexed citations

13.

Bikker, Jack, Susanne Trumpp-Kallmeyer, & Christine Humblet. (1998). G-Protein Coupled Receptors: Models, Mutagenesis, and Drug Design. Journal of Medicinal Chemistry. 41(16). 2911–2927. 100 indexed citations

14.

Haskell‐Luevano, Carrie, Tomi K. Sawyer, Susanne Trumpp-Kallmeyer, et al.. (1996). Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.. PubMed. 14(3). 197–211. 61 indexed citations

15.

Chung, Fu‐Zon, Yuan Tian, Maida Vartanian, et al.. (1995). Two classes of structurally different antagonists display similar species preference for the human tachykinin neurokinin3 receptor.. Molecular Pharmacology. 48(4). 711–716. 39 indexed citations

16.

Bikker, Jack, Julia Kubanek, & Donald F. Weaver. (1994). Quantum Pharmacologic Studies Applicable to the Design of Anticonvulsants: Theoretical Conformational Analysis and Structure‐Activity Studies of Barbiturates. Epilepsia. 35(2). 411–425. 10 indexed citations

17.

Bikker, Jack & Donald F. Weaver. (1993). Theoretical studies applicable to the design of novel anticonvulsants. Journal of Molecular Structure THEOCHEM. 281(2-3). 173–184. 17 indexed citations

18.

Bikker, Jack & Donald F. Weaver. (1992). Theoretical studies applicable to the design of novel anticonvulsants: an AM1 molecular orbital structure–activity study of dihydropyridine calcium channel antagonists. Canadian Journal of Chemistry. 70(9). 2449–2460. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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