Michael S. Malamas

4.4k citations

71 papers · 3.3k indexed · 1 hit paper · h-index 27

Impact in

Toxicology top 1%
Organic Chemistry top 2%
- Synthesis and biological activity
- Quinazolinone synthesis and applications
- Catalytic C–H Functionalization Methods

Papers in

Pharmacology 30
- Cannabis and Cannabinoid Research 19
- Cholinesterase and Neurodegenerative Diseases 6
Toxicology 3

Co-authors: Jane Millen Jonathan Bard Rebecca Cowling Ann Aulabaugh Guixian Jin Mei-Chu Lo George A. Ellestad Heather A. Harris
Journals: Journal of Medicinal Chemistry (14 papers)Bioorganic & Medicinal Chemistry Letters (9 papers)Bioorganic & Medicinal Chemistry (6 papers)The Journal of Organic Chemistry (4 papers)Scientific Reports (2 papers)
Partner nations: United States Greece Canada

In The Last Decade

Michael S. Malamas

70 papers receiving 3.2k citations

Hit Papers

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Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery 2004 · 533 citations

Peers

Countries citing papers authored by Michael S. Malamas

Since Specialization

Citations

This map shows the geographic impact of Michael S. Malamas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael S. Malamas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael S. Malamas more than expected).

Fields of papers citing papers by Michael S. Malamas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael S. Malamas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael S. Malamas. The network helps show where Michael S. Malamas may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael S. Malamas, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael S. Malamas Line = papers co-authored together Michael S. Malamas links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	P2X₇ receptor‐dependent increase in endocannabinoid 2‐arachidonoyl glycerol production by neuronal cells in culture: Dynamics and mechanism British Journal of Pharmacology ·Simar Singh, Shibo Wu, Jamaludin F. A, Dale Whittington, Ao Dong, Michael S. Malamas, Alexandros Makriyannis, Mario van der Stelt, Yulong Li, Larry S. Zweifel, Michael R. Bruchas, Benjamin B. Land, Nephi Stella	2024	2
2	Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina International Journal of Molecular Sciences ·Michael Eulenberg, Marcelo de Araújo Lino, (unknown), Nikos A. Chaniotakis, Alexandros Makriyannis, Michael S. Malamas, Kyriaki Thermos	2023	3
3	Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase Scientific Reports ·Othman Benchama, Sergiy Tyukhtenko, Michael S. Malamas, Mark Williams, Alexandros Makriyannis, Hava Avraham	2022	12
4	N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice Neurotherapeutics ·Pauline Bottemanne, Owein Guillemot‐Legris, Adrien Paquot, Julien Masquelier, Michael S. Malamas, Alexandros Makriyannis, Mireille Alhouayek, Giulio G. Muccioli	2021	7
5	Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology Bioorganic & Medicinal Chemistry ·Manjunath Lamani, Michael S. Malamas, Siran Fang, Vidyanand G. Shukla, Andrew P. Winterstein, 卜书庆, Joseph S. Anderson, JodiAnne T. Wood, 翟书颖, Ben A. Bahr, Alexandros Makriyannis	2019	11
6	Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors Bioorganic & Medicinal Chemistry ·Michael S. Malamas, Siran Fang, Manjunath Lamani, MO Bang-hon, Nicholas T. Perry, Артем Лучко, Paola Marcela Del Cid Amaya, Chandrashekhar Honrao, D.L. Henshaw, Spiro Pavlopoulos, Alexandros Makriyannis	2019	17
7	Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment Bioorganic & Medicinal Chemistry ·Shakiru O. Alapafuja, Michael S. Malamas, Vidyanand G. Shukla, A. M. Zvonok, Sally Miller, Mohamad Fajri Mekka Putra, Артем Лучко, Paola Marcela Del Cid Amaya, Chandrashekhar Honrao, JodiAnne T. Wood, Sergiy Tyukhtenko, Alex Straiker, Alexandros Makriyannis	2018	6
8	Oximes short-acting CB1 receptor agonists Bioorganic & Medicinal Chemistry ·Michael S. Malamas, Cheng Yuan, Xiaoyu Ma, Chandrashekhar Honrao, JodiAnne T. Wood, Othman Benchama, Han Zhou, Walter McQuade, Alexandros Makriyannis	2018	8
9	Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies Protein Expression and Purification ·Spiro Pavlopoulos, MO Bang-hon, Othman Benchama, Catherine M. Rawlins, Jeffrey N. Agar, D.L. Henshaw, Michael S. Malamas, Nikolai Zvonok, Alexandros Makriyannis	2017	2
10	New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: Exploring the S2′ region Bioorganic & Medicinal Chemistry Letters ·Michael S. Malamas, 和生浅野, Iwan Gunawan, Keith D. Barnes, Hui Yu, Matthew R. Johnson, Albert J. Robichaud, Ping Zhou, Yinfa Yan, Nisarut Phansiri, Jim Turner, Kristi Fan, Rajiv Chopra, Jonathan Bard, Menelas N. Pangalos	2011	24
11	Estrogen Receptor β Agonism Increases Survival in Experimentally Induced Sepsis and Ameliorates the Genomic Sepsis Signature: A Pharmacogenomic Study The Journal of Infectious Diseases ·Eirini Christaki, Steven M. Opal, James C. Keith, Xincheng Lin, John E. Palardy, Nicolas A. Parejo, Edward R. LaVallie, Pip McDonald, William Mounts, Michael S. Malamas, Richard E. Mewshaw, Heather A. Harris, George P. Vlasuk	2010	36
12	Pyridinyl aminohydantoins as small molecule BACE1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Ping Zhou, Yanfang Li, Yi Fan, Zheng Wang, Rajiv Chopra, Andrea Olland, Yun Hu, Ronald L. Magolda, Menelas N. Pangalos, Peter H. Reinhart, Актамова Васила Укатамовна, Jonathan Bard, Michael S. Malamas, Albert J. Robichaud	2010	27
13	Di-substituted pyridinyl aminohydantoins as potent and highly selective human β-secretase (BACE1) inhibitors Bioorganic & Medicinal Chemistry ·Michael S. Malamas, Keith D. Barnes, Matthew R. Johnson, Hui Yu, Ping Zhou, Jim Turner, Yun Hu, Erik Wagner, Kristi Fan, Rajiv Chopra, Andrea Olland, Jonathan Bard, Menelas N. Pangalos, Peter H. Reinhart, Albert J. Robichaud	2009	38
14	Clinical pharmacology of celecoxib, a COX-2 selective inhibitor Expert Opinion on Pharmacotherapy ·Katerina Antoniou, Michael S. Malamas, Alexandros A. Drosos	2007	26
15	Thiophene substituted acylguanidines as BACE1 inhibitors Bioorganic & Medicinal Chemistry Letters ·William F. Fobare, Nisarut Phansiri, Albert J. Robichaud, Michael S. Malamas, Eric S. Manas, Jim Turner, Yun Hu, Erik Wagner, Rajiv Chopra, Rebecca Cowling, Renata C. Carvalho de Souza, Jonathan Bard	2007	49
16	New oxadiazolidinedione derivatives as potent and selective human β3 agonists Bioorganic & Medicinal Chemistry Letters ·Baihua Hu, Michael S. Malamas, John W. Ellingboe, Elwood Largis, Stella Han, 张晓涛, Masatsune Kainosho	2001	18
17	Probing the inhibitor‐binding site of aldose reductase with site‐directed mutagenesis European Journal of Biochemistry ·Thomas C. Hohman, Ossama El‐Kabbani, Michael S. Malamas, KehDih Lai, 尚行船水, ZHANG Jinjing, Joseph Prinke, Deborah Carper	1998	21
18	Comparison of the therapeutic effects of two vanadium complexes administered at low doses on benzo[a]pyrene-induced malignant tumors in rats Cancer Letters ·Angelos Evangelou, S. Karkabounas, Yikun Xiu, Michael S. Malamas, Roman Liasko, Aning Ayu Amaliyah, Abraham Balsam, Themistoklis A. Kabanos	1997	45
19	N-Substituted Spirosuccinimide, Spiropyridazine, Spiroazetidine, and Acetic Acid Aldose Reductase Inhibitors Derived from Isoquinoline-1,3-diones. 2 Journal of Medicinal Chemistry ·Michael S. Malamas, Thomas C. Hohman	1994	22
20	Novel Spirosuccinimide Aldose Reductase Inhibitors Derived from Isoquinoline-1,3-diones: 2-[(4-Bromo-2-fluorophenyl)methyl]-6-fluorospiro[isoquinoline-4(11H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and Congeners. 1 Journal of Medicinal Chemistry ·Michael S. Malamas, T. C. Hohman, Jane Millen	1994	79

About Michael S. Malamas

Michael S. Malamas is a scholar working on Pharmacology, Toxicology, Organic Chemistry, Physiology and Biochemistry, having authored 71 papers that have together received 3.3k indexed citations. Recurring topics across this work include Cannabis and Cannabinoid Research (19 papers), Alzheimer's disease research and treatments (8 papers), Aldose Reductase and Taurine (7 papers), Receptor Mechanisms and Signaling (7 papers), Computational Drug Discovery Methods (6 papers), Cholinesterase and Neurodegenerative Diseases (6 papers), Chemical Synthesis and Analysis (5 papers) and Estrogen and related hormone effects (5 papers). The work is most often cited by research in Toxicology (144 citations), Organic Chemistry (1.2k citations), Pharmacology (610 citations), Computational Theory and Mathematics (461 citations) and Molecular Biology (1.5k citations). Michael S. Malamas has collaborated with scholars based in United States, Greece and Canada. Frequent co-authors include Jane Millen, Jonathan Bard, Rebecca Cowling, Ann Aulabaugh, Guixian Jin, Mei-Chu Lo, George A. Ellestad, Heather A. Harris, Chris P. Miller and Iwan Gunawan. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry, The Journal of Organic Chemistry and Scientific Reports.

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