Dean A. Wacker

742 citations

19 papers · 414 indexed · h-index 12

Organic Chemistry top 10%
- Synthesis and Biological Evaluation 4
Pharmaceutical Science top 10%
Microbiology
- Antimicrobial Peptides and Activities 3
Molecular Biology
- Chemical Synthesis and Analysis 5
- Receptor Mechanisms and Signaling 4
- RNA and protein synthesis mechanisms 3
Cellular and Molecular Neuroscience
- Neuroscience and Neuropharmacology Research 2
Physiology
- Asthma and respiratory diseases 3
Cardiology and Cardiovascular Medicine
- Atrial Fibrillation Management and Outcomes 2

Co-authors: A. Richard Chamberlin Jenny Bain Keith J. Miller Matthew H. Lyttle Edward S. Diala Thomas A. Dix Charles Glabe Jeffrey Varnes
Cited by: Organic Chemistry Pharmaceutical Science Microbiology
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Tetrahedron Letters (2 papers)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: United States Germany Sweden

In The Last Decade

Dean A. Wacker

18 papers receiving 394 citations

Peers

Countries citing papers authored by Dean A. Wacker

Since Specialization

Citations

This map shows the geographic impact of Dean A. Wacker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dean A. Wacker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dean A. Wacker more than expected).

Fields of papers citing papers by Dean A. Wacker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dean A. Wacker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dean A. Wacker. The network helps show where Dean A. Wacker may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Dean A. Wacker, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dean A. Wacker Line = papers co-authored together Dean A. Wacker links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Discovery of BMS-986318, a Potent Nonbile Acid FXR Agonist for the Treatment of Nonalcoholic Steatohepatitis ACS Medicinal Chemistry Letters ·Joseph Carpenter,Gang Wu,Ying Wang,송주완,Tao Wang,Doree Sitkoff,Karen A. Rossi,Kathy Mosure,Xiaoliang Zhuo,سیدکیوان حسینی,Kristina Sykes,Anthony V. Azzara,豊長原,Matthew G. Soars,Bruce A. Ellsworth,Dean A. Wacker	2021	6
2	Synthesis and structure–activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists Bioorganic & Medicinal Chemistry Letters ·Xiang‐Yang Ye,淳吉永,Ying Wang,Karen A. Rossi,X. Li,Alexandre Denizot,Larisa Sereda,Atsu Apedo,Jeffrey A. Robl,Keith J. Miller,John Krupinski,Dean A. Wacker	2014	18
3	Discovery and Development of 5-HT_2CReceptor Agonists for Obesity: Is There Light at the End of the Tunnel? Future Medicinal Chemistry ·Keith J. Miller,Dean A. Wacker	2010	3
4	Position 5.46 of the Serotonin 5-HT2A Receptor Contributes to a Species-Dependent Variation for the 5-HT2C Agonist (R)-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: Impact on Selectivity and Toxicological Evaluation Molecular Pharmacology ·Keith J. Miller,Ginger Wu,Jeffrey Varnes,Paul Lévesque,V. Lyubin,Danshi Li,Jeffrey A. Robl,Karen A. Rossi,Dean A. Wacker	2009	8
5	Agonists of the serotonin 5-HT2C receptor: preclinical and clinical progression in multiple diseases. PubMed ·Dean A. Wacker,Keith J. Miller	2008	30
6	Structure–activity relationship and pharmacokinetic profile of 5-ketopyrazole factor Xa inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey Varnes,Dean A. Wacker,Donald Pinto,Michael J. Orwat,Jay Theroff,Ananda Rizqi Johansyah,T. Hallina,Joseph M. Luettgen,Robert M. Knabb,Steven Bai,Kan He,Patrick Y. S. Lam,Ruth R. Wexler	2007	29
7	Design, structure–activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey Varnes,Dean A. Wacker,夏映雪,Mimi L. Quan,Christopher D. Ellis,Karen A. Rossi,Nedorezova Ai,Joseph M. Luettgen,Robert M. Knabb,Steven Bai,Kan He,Patrick Y. S. Lam,Ruth R. Wexler	2007	18
8	N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists Bioorganic & Medicinal Chemistry Letters ·Douglas G. Batt,Ruziye ÖZSOY,John Roderick,Joseph B. Santella,Dean A. Wacker,Aslam Mohammad,خالد مطهر العدواني,Eric Wadman,James M. Trzăskos,Paul Davies,Carl P. Decicco,Percy H. Carter	2004	12
9	Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists Bioorganic & Medicinal Chemistry Letters ·Jeffrey Varnes,Daniel S. Gardner,Joseph B. Santella,John V. Duncia,Keyaki Yoichiro Miyasak,Paul S. Watson,Tara Suntum,Soo S. Ko,Lučka Lešnik,Maryanne Covington,Nicole Stowell,Eric Wadman,Paul Davies,Pilar Pérez Chaparro,Robert Newton,George L. Trainor,Carl P. Decicco,Dean A. Wacker	2004	21
10	Solid-Phase Synthesis of Alkyl Aryl Ethers via the Ullmann Condensation Journal of Combinatorial Chemistry ·Xiao Xiao,Rongshi Li,David C. Hurst,Hui Zhuang,Shuhao Shi,Anthony W. Czarnik,Albert J. Robichaud,Dean A. Wacker,David W. Robertson	2002	7
11	CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships Bioorganic & Medicinal Chemistry Letters ·Dean A. Wacker,Joseph B. Santella,Daniel S. Gardner,Jeffrey Varnes,Keyaki Yoichiro Miyasak,CD Cowper-Smith,Soo S. Ko,哲夫長瀬,Paul S. Watson,Aslam Mohammad,Maryanne Covington,Nicole Stowell,Eric Wadman,Paul Davies,Kimberly A. Solomon,Robert Newton,George L. Trainor,Steven Friedman,Carl P. Decicco,John V. Duncia	2002	35
12	Efficient solid-phase synthesis of 2,3-substituted indoles Tetrahedron Letters ·Dean A. Wacker,Una Matko Stamenković	2002	40
13	CCR3 Antagonists: A Potential New Therapy for the Treatment of Asthma. Discovery and Structure—Activity Relationships. ChemInform ·Dean A. Wacker,John V. Duncia,(unknown)	2002	0
14	Irreversible Inhibition of High‐Affinity [³H]Kainate Binding by a Novel Photoactivatable Analogue: (2′S,3′S,4′R)‐2′‐Carboxy‐4′‐(2‐Diazo‐1‐Oxo‐3,3,3‐Trifluoropropyl)‐3′‐Pyrrolidinyl Acetate Journal of Neurochemistry ·Colin L. Willis,Dean A. Wacker,Richard D. Bartlett,David Bleakman,David Lodge,A. Richard Chamberlin,Richard J. Bridges	1997	8
15	A Selective Photoaffinity Ligand for the Kainate Class of Excitatory Amino Acid Receptor Synlett ·Dean A. Wacker,Frank Lovering,Richard J. Bridges,Colin L. Willis,Richard D. Bartlett,A. Richard Chamberlin	1997	2
16	Facile preparation of chloromethylaryl solid supports using methanesulfonyl chloride and Hunig's base Tetrahedron Letters ·David A. Nugiel,Dean A. Wacker,Gregory A. Nemeth	1997	13
17	Site-specific incorporation of nonnatural residues during in vitro protein biosynthesis with semi-synthetic aminoacyl-tRNAs Biochemistry ·Jenny Bain,Edward S. Diala,Charles Glabe,Dean A. Wacker,Matthew H. Lyttle,Thomas A. Dix,A. Richard Chamberlin	1991	89
18	Preparation of chemically misacylated semisynthetic nonsense suppressor tRNAs employed in biosynthetic incorporation of non-natural residues into proteins The Journal of Organic Chemistry ·Jenny Bain,Dean A. Wacker,Elizabeth Harari,Matthew H. Lyttle,A. Richard Chamberlin	1991	23
19	Site-specific incorporation of non-natural residues into peptides: Effect of residue structure on suppression and translation efficiencies Tetrahedron ·Jenny Bain,Dean A. Wacker,Elizabeth Harari,A. Richard Chamberlin	1991	52

About Dean A. Wacker

Dean A. Wacker is a scholar working on Microbiology, Organic Chemistry, Cellular and Molecular Neuroscience, Hematology and Molecular Biology, having authored 19 papers that have together received 414 indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (5 papers), Receptor Mechanisms and Signaling (4 papers), Synthesis and Biological Evaluation (4 papers), Antimicrobial Peptides and Activities (3 papers), Asthma and respiratory diseases (3 papers), RNA and protein synthesis mechanisms (3 papers), Neuroscience and Neuropharmacology Research (2 papers) and Atrial Fibrillation Management and Outcomes (2 papers). The work is most often cited by research in Organic Chemistry (150 citations), Pharmaceutical Science (29 citations), Microbiology (24 citations), Molecular Biology (248 citations) and Cellular and Molecular Neuroscience (60 citations). Dean A. Wacker has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include A. Richard Chamberlin, Jenny Bain, Keith J. Miller, Matthew H. Lyttle, Edward S. Diala, Thomas A. Dix, Charles Glabe, Jeffrey Varnes, Robert M. Knabb and Kan He. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, ACS Medicinal Chemistry Letters, Tetrahedron and Synlett.

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