Paul Helquist

6.7k citations

169 papers · 4.9k indexed · h-index 37

Impact in

Organic Chemistry top 0.5%
- Asymmetric Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
- Catalytic Cross-Coupling Reactions
- Cyclopropane Reaction Mechanisms
Inorganic Chemistry top 1%
- Asymmetric Hydrogenation and Catalysis

Papers in

Organic Chemistry 125
- Synthetic Organic Chemistry Methods 32
- Cyclopropane Reaction Mechanisms 24
- Catalytic C–H Functionalization Methods 22
- Catalytic Cross-Coupling Reactions 21
- Asymmetric Synthesis and Catalysis 21
- Organometallic Complex Synthesis and Catalysis 13
Inorganic Chemistry 32
- Asymmetric Hydrogenation and Catalysis 29

Co-authors: Olaf Wiest Per‐Ola Norrby M. F. SEMMELHACK Norbert L. Wiech Casey C. Cosner L. Jones Difei Wang Björn Åkermark
Journals: The Journal of Organic Chemistry (35 papers)Tetrahedron Letters (30 papers)Journal of the American Chemical Society (22 papers)Organic Letters (12 papers)Organometallics (6 papers)
Partner nations: United States Sweden China

In The Last Decade

Paul Helquist

166 papers receiving 4.8k citations

Peers

Countries citing papers authored by Paul Helquist

Since Specialization

Citations

This map shows the geographic impact of Paul Helquist's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul Helquist with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul Helquist more than expected).

Fields of papers citing papers by Paul Helquist

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul Helquist. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul Helquist. The network helps show where Paul Helquist may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Paul Helquist, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul Helquist Line = papers co-authored together Paul Helquist links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mutant induced neurons and humanized mice enable identification of Niemann-Pick type C1 proteostatic therapies JCI Insight ·Camilo. Peraza Fandiño, Kercia Vitória de Moura Rêgo Melo, DEMOGO studio di architettura, R Elaiyaraja, Wahyu Alam Firdaus Syahuri, Nico Heußner, XinBing Sui, Brandon L. Ashfeld, Paul Helquist, Olaf Wiest, Kenji Ohgane, Qingqing Li, Ross A. Fredenburg, Brian S. J. Blagg, Stephanie M. Cologna, Mark L. Schultz, Andrew P. Lieberman	2024	0
2	pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography Biophysical Journal ·Tung-Sheng Wang, C.N. Steussy, Anthony R. Rosales, L. Fraenkel, Tim Schmidt, Paul Helquist, Olaf Wiest, Andrew D. Mesecar, Aina E. Cohen, Cynthia V. Stauffacher	2024	2
3	Biocompatible, Multi-Mode, Fluorescent, T2 MRI Contrast Magnetoelectric-Silica Nanoparticles (MagSiNs), for On-Demand Doxorubicin Delivery to Metastatic Cancer Cells Pharmaceuticals ·刘宏波, 孝一下, L Vela, Stephanie E Wallace, 九二, 鴨川郁子, Tom Haim Ron, Ryan K. Roeder, Paul Helquist, M. Sharon Stack, Prakash D. Nallathamby	2022	6
4	HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts Journal of Lipid Research ·Nina H. Pipalia, Pavel Belovus, Kanagaraj Subramanian, 亜由美月足, R. S. Bykov, Jessica Tanzil, Brian S. J. Blagg, Len Neckers, Paul Helquist, Olaf Wiest, Daniel Ory, Frederick R. Maxfield	2021	12
5	Structural insights into HDAC6 tubulin deacetylation and its selective inhibition Nature Chemical Biology ·Y. Miyake, J.J. Keusch, Longlong Wang, Makoto Saito, Daniel Heß, Xiao‐Ning Wang, Bruce J. Melancon, Paul Helquist, H. Gut, Patrick Matthias	2016	234
6	Single‐Flask Multicomponent Palladium‐Catalyzed α,γ‐Coupling of Ketone Enolates: Facile Preparation of Complex Carbon Scaffolds Angewandte Chemie International Edition ·Michael Grigalunas, Per‐Ola Norrby, Olaf Wiest, Paul Helquist	2015	19
7	Design and synthesis of a crosslinker for studying intracellular steroid trafficking pathways Bioorganic & Medicinal Chemistry ·Л М Бурмакова, Néstor Yim Costilla Ventura, Sverrir Karl Björnsson, Guillermina Estiú, Olaf Wiest, Paul Helquist	2015	5
8	Development of carbamate-tethered coumarins as phototriggers for caged nicotinamide Bioorganic & Medicinal Chemistry Letters ·Pauline Bourbon, Qian Peng, G. Ferraudi, Cynthia V. Stauffacher, Olaf Wiest, Paul Helquist	2013	15
9	Palladium‐ and Nickel‐Catalyzed Alkenylation of Enolates Chemistry - A European Journal ·Tobias Ankner, Casey C. Cosner, Paul Helquist	2013	79
10	Synthesis and photochemical behavior of coumarin-caged cholesterol Bioorganic & Medicinal Chemistry Letters ·Pauline Bourbon, Qian Peng, G. Ferraudi, Cynthia V. Stauffacher, Olaf Wiest, Paul Helquist	2013	13
11	Treatment of Niemann–Pick Type C Disease by Histone Deacetylase Inhibitors Neurotherapeutics ·Paul Helquist, Frederick R. Maxfield, Norbert L. Wiech, Olaf Wiest	2013	41
12	Quantitative Comparison of the Efficacy of Various Compounds in Lowering Intracellular Cholesterol Levels in Niemann-Pick Type C Fibroblasts PLoS ONE ·Weiying Wen, Tyler Hulett, Zahra Ghayumi, Kevin T. Vaughan, Olaf Wiest, Paul Helquist, Holly V. Goodson	2012	25
13	Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening Bioorganic & Medicinal Chemistry ·Kristoff T. Homan, Byoung-Sam Yoo, 张哲华, Olaf Wiest, Paul Helquist, Cynthia V. Stauffacher	2010	10
14	Iejimalides A and B inhibit lysosomal vacuolar H⁺‐ATPase (V‐ATPase) activity and induce S‐phase arrest and apoptosis in MCF‐7 cells Journal of Cellular Biochemistry ·Clotilde Guidi T., Tae-soon Moon, Barry Li, Roger Giraud, V. Jo Davisson, Edward E. McKee, Dirk Schweitzer, Paul Helquist, Martin Tenniswood	2009	29
15	Inhibition of Histone Deacetylases: A Pharmacological Approach to the Treatment of Non-Cancer Disorders Current Topics in Medicinal Chemistry ·Norbert L. Wiech, Jed F. Fisher, Paul Helquist, Olaf Wiest	2009	60
16	Design and synthesis of a siderophore conjugate as a potent PSMA inhibitor and potential diagnostic agent for prostate cancer Bioorganic & Medicinal Chemistry ·Pingyu Ding, Paul Helquist, Marvin J. Miller	2007	7
17	QSAR Studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids Bioorganic & Medicinal Chemistry Letters ·Difei Wang, Olaf Wiest, Paul Helquist, Mayra Bif, Norbert L. Wiech	2004	32
18	Conformational and SAR analysis of NAALADase and PSMA inhibitors Bioorganic & Medicinal Chemistry ·Allen G. Oliver, Olaf Wiest, Paul Helquist, Marvin J. Miller, Martin Tenniswood	2003	18
19	Generation and use of a zinc derivative of a functionalized 1,3-oxazole. Solution of the virginiamycin/madumycin oxazole problem The Journal of Organic Chemistry ·Anthony R. Gangloff, Bjoern Aakermark, Paul Helquist	1992	27
20	Functionalized aryllithium intermediates. A synthesis of benzocyclobutenes. Tetrahedron Letters ·P. D. Brewer, Jayaram R. Tagat, Charles A. Hergrueter, Paul Helquist	1977	7

About Paul Helquist

Paul Helquist is a scholar working on Organic Chemistry, Inorganic Chemistry, Pharmaceutical Science, Physiology and Process Chemistry and Technology, having authored 169 papers that have together received 4.9k indexed citations. Recurring topics across this work include Synthetic Organic Chemistry Methods (32 papers), Asymmetric Hydrogenation and Catalysis (29 papers), Cyclopropane Reaction Mechanisms (24 papers), Catalytic C–H Functionalization Methods (22 papers), Catalytic Cross-Coupling Reactions (21 papers), Asymmetric Synthesis and Catalysis (21 papers), Chemical Synthesis and Analysis (20 papers) and Organometallic Complex Synthesis and Catalysis (13 papers). The work is most often cited by research in Organic Chemistry (3.2k citations), Inorganic Chemistry (840 citations), Pharmaceutical Science (178 citations), Molecular Biology (1.6k citations) and Physiology (103 citations). Paul Helquist has collaborated with scholars based in United States, Sweden and China. Frequent co-authors include Olaf Wiest, Per‐Ola Norrby, M. F. SEMMELHACK, Norbert L. Wiech, Casey C. Cosner, L. Jones, Difei Wang, Björn Åkermark, Anthony Marfat and Patrick J. Donoghue. Their work appears in journals such as The Journal of Organic Chemistry, Tetrahedron Letters, Journal of the American Chemical Society, Organic Letters and Organometallics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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