Tatos Akopian

4.0k total citations
25 papers, 2.9k citations indexed

About

Tatos Akopian is a scholar working on Molecular Biology, Infectious Diseases and Oncology. According to data from OpenAlex, Tatos Akopian has authored 25 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 6 papers in Infectious Diseases and 6 papers in Oncology. Recurrent topics in Tatos Akopian's work include Ubiquitin and proteasome pathways (10 papers), Biochemical and Molecular Research (7 papers) and Tuberculosis Research and Epidemiology (6 papers). Tatos Akopian is often cited by papers focused on Ubiquitin and proteasome pathways (10 papers), Biochemical and Molecular Research (7 papers) and Tuberculosis Research and Epidemiology (6 papers). Tatos Akopian collaborates with scholars based in United States, Spain and Portugal. Tatos Akopian's co-authors include Alfred L. Goldberg, Alexei F. Kisselev, Kenneth L. Rock, Kee Min Woo, Abie Craiu, Olga Kandror, Eric J. Rubin, Maria Gaczyńska, Gabriel Fenteany and Colette F. Gramm and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Tatos Akopian

25 papers receiving 2.8k citations

Peers

Tatos Akopian
Jonathan Greene United States
Edward Nieves United States
Scott J. Snipas United States
Christophe Briand Switzerland
Martin Renatus United States
Hakim Djaballah United States
Nir London Israel
Richard Marcellus Canada
Achim Dickmanns Germany
Kurt E. Amrein Switzerland
Jonathan Greene United States
Tatos Akopian
Citations per year, relative to Tatos Akopian Tatos Akopian (= 1×) peers Jonathan Greene

Countries citing papers authored by Tatos Akopian

Since Specialization
Citations

This map shows the geographic impact of Tatos Akopian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tatos Akopian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tatos Akopian more than expected).

Fields of papers citing papers by Tatos Akopian

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tatos Akopian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tatos Akopian. The network helps show where Tatos Akopian may publish in the future.

Co-authorship network of co-authors of Tatos Akopian

This figure shows the co-authorship network connecting the top 25 collaborators of Tatos Akopian. A scholar is included among the top collaborators of Tatos Akopian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tatos Akopian. Tatos Akopian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Weinhäupl, Katharina, Sandy Desrat, Catherine Guillou, et al.. (2025). Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development. Scientific Reports. 15(1). 4146–4146. 1 indexed citations
2.
Kandror, Olga, Tatos Akopian, E. Schmid, et al.. (2024). Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy. Nature Communications. 15(1). 4065–4065. 10 indexed citations
3.
Weinhäupl, Katharina, Marcos Gragera, Rocío Arranz, et al.. (2022). Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. Journal of Biological Chemistry. 298(11). 102553–102553. 15 indexed citations
4.
Gopal, Pooja, Jickky Palmae Sarathy, Michelle Yee, et al.. (2020). Pyrazinamide triggers degradation of its target aspartate decarboxylase. Nature Communications. 11(1). 1661–1661. 63 indexed citations
5.
Fraga, Hugo, Ana I. Bardera, Tatos Akopian, et al.. (2018). Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis. Analytical Biochemistry. 567. 30–37. 16 indexed citations
6.
Lehmann, Johannes, Tan‐Yun Cheng, Anup Aggarwal, et al.. (2017). An Antibacterial β‐Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis. Angewandte Chemie International Edition. 57(1). 348–353. 51 indexed citations
7.
Lehmann, Johannes, Tan‐Yun Cheng, Anup Aggarwal, et al.. (2017). Ein antibakterielles β‐Lacton bekämpft Mycobacterium tuberculosis durch Infiltration der Mykolsäurebiosynthese. Angewandte Chemie. 130(1). 354–359. 3 indexed citations
8.
Li, Mi, Olga Kandror, Tatos Akopian, et al.. (2016). Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. Journal of Biological Chemistry. 291(14). 7465–7476. 38 indexed citations
9.
Saß, Peter, Imran T. Malik, Tatos Akopian, et al.. (2016). Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease. Molecular Microbiology. 101(2). 194–209. 69 indexed citations
10.
Akopian, Tatos, Olga Kandror, Christopher Tsu, et al.. (2015). Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity. Journal of Biological Chemistry. 290(17). 11008–11020. 48 indexed citations
11.
Gavrish, Ekaterina, Clarissa S. Sit, Shugeng Cao, et al.. (2014). Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2. Chemistry & Biology. 21(4). 509–518. 315 indexed citations
12.
Raju, Ravikiran M., Meera Unnikrishnan, Daniel H. F. Rubin, et al.. (2012). Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection. PLoS Pathogens. 8(2). e1002511–e1002511. 141 indexed citations
13.
Akopian, Tatos, Olga Kandror, Ravikiran M. Raju, et al.. (2012). The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring. The EMBO Journal. 31(6). 1529–1541. 103 indexed citations
14.
Šarić, Tomo, et al.. (2001). Major Histocompatibility Complex Class I-presented Antigenic Peptides Are Degraded in Cytosolic Extracts Primarily by Thimet Oligopeptidase. Journal of Biological Chemistry. 276(39). 36474–36481. 112 indexed citations
15.
Kisselev, Alexei F., et al.. (1999). Proteasome Active Sites Allosterically Regulate Each Other, Suggesting a Cyclical Bite-Chew Mechanism for Protein Breakdown. Molecular Cell. 4(3). 395–402. 227 indexed citations
16.
Kisselev, Alexei F., Tatos Akopian, Kee Min Woo, & Alfred L. Goldberg. (1999). The Sizes of Peptides Generated from Protein by Mammalian 26 and 20 S Proteasomes. Journal of Biological Chemistry. 274(6). 3363–3371. 444 indexed citations
17.
Kisselev, Alexei F., Tatos Akopian, & Alfred L. Goldberg. (1998). Range of Sizes of Peptide Products Generated during Degradation of Different Proteins by Archaeal Proteasomes. Journal of Biological Chemistry. 273(4). 1982–1989. 165 indexed citations
18.
Goldberg, Alfred L., Tatos Akopian, Alexei F. Kisselev, & Do Hee Lee. (1997). Protein degradation by the proteasome and dissection of its in vivo importance with synthetic inhibitors. Molecular Biology Reports. 24(1-2). 69–75. 23 indexed citations
19.
Akopian, Tatos, Alexei F. Kisselev, & Alfred L. Goldberg. (1997). Processive Degradation of Proteins and Other Catalytic Properties of the Proteasome from Thermoplasma acidophilum. Journal of Biological Chemistry. 272(3). 1791–1798. 170 indexed citations
20.
Craiu, Abie, Maria Gaczyńska, Tatos Akopian, et al.. (1997). Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation. Journal of Biological Chemistry. 272(20). 13437–13445. 348 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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