Derek C. Cole

2.8k citations

39 papers · 1.9k indexed · h-index 21

Impact in

Organic Chemistry top 2%
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Synthesis and Catalytic Reactions
Molecular Biology top 10%
- Chemical Synthesis and Analysis
- PI3K/AKT/mTOR signaling in cancer
- Receptor Mechanisms and Signaling

Papers in

Organic Chemistry 18
- Synthesis and biological activity 7
- Synthesis and Reactivity of Heterocycles 3
Molecular Biology 25
- Protein Kinase Regulation and GTPase Signaling 6
- Receptor Mechanisms and Signaling 5
- Chemical Synthesis and Analysis 5
- Redox biology and oxidative stress 3

Co-authors: John W. Ellingboe Deborah L. Smith Lee E. Schechter Paul Jackson Barbara S. Slusher Diane A. Trainor Bruce A. Donzanti Paweł Nowak
Journals: Bioorganic & Medicinal Chemistry Letters (12 papers)Journal of Medicinal Chemistry (10 papers)The Journal of Organic Chemistry (3 papers)Journal of the American Chemical Society (1 paper)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: United States Canada Japan

In The Last Decade

Derek C. Cole

38 papers receiving 1.9k citations

Peers

Countries citing papers authored by Derek C. Cole

Since Specialization

Citations

This map shows the geographic impact of Derek C. Cole's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Derek C. Cole with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Derek C. Cole more than expected).

Fields of papers citing papers by Derek C. Cole

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Derek C. Cole. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Derek C. Cole. The network helps show where Derek C. Cole may publish in the future.

Co-authors

The 25 scholars most cited alongside Derek C. Cole, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Derek C. Cole Line = papers co-authored together Derek C. Cole links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Novel peptide binder for EphA2-targeted radiopharmaceutical therapy for multiple solid tumors. Journal of Clinical Oncology ·Renee Clift, Samantha J. Richardson, Takeru Ehara, Hayato Yanagida, Ivy Hung, Zaid Amso, Katrina Salvador, M. Mason Guest, Guangzhou Han, Abhijit Bhat, Derek C. Cole, Eric D. Bischoff, Gary Li	2023	0
2	Bleeding rates of Veterans taking apixaban or rivaroxaban for atrial fibrillation or venous thromboembolism Journal of Thrombosis and Thrombolysis ·Zachary Howe, Chad Naville-Cook, Derek C. Cole	2018	6
3	Structure-based drug design of novel ASK1 inhibitors using an integrated lead optimization strategy Bioorganic & Medicinal Chemistry Letters ·Tony Gibson, Benjamin Johnson, Andrea Fanjul, Petro Halkowycz, Douglas R. Dougan, Derek C. Cole, Steven Swann	2017	15
4	A Fragment-Based Approach to IdentifyingS-Adenosyl-l-methionine -Competitive Inhibitors of CatecholO-Methyl Transferase (COMT). Journal of Medicinal Chemistry ·Marion Lanier, Géza Ambrus, Derek C. Cole, Richard Davenport, Jonathan Ellery, Richard Fosbeary, Andy Jennings, Akito Kadotani, Yusuke Kamada, Ruhi Kamran, Shin-ichi Matsumoto, Atsushi Mizukami, Shoichi Okubo, Kengo Okada, Kumar Singh Saikatendu, Louise Walsh, Haihong Wu, Mark S. Hixon	2014	10
5	Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Yike Ni, Ariamala Gopalsamy, Derek C. Cole, Yonghan Hu, R. Aldrin Denny, Manus Ipek, Julie Liu, Julie Lee, J. Perry Hall, Michael Luong, Jean‐Baptiste Telliez, Lih‐Ling Lin	2011	27
6	Discovery of indazoles as inhibitors of Tpl2 kinase Bioorganic & Medicinal Chemistry Letters ·Yonghan Hu, Derek C. Cole, R. Aldrin Denny, David R. Anderson, Manus Ipek, Yike Ni, Xiaolun Wang, Suvit Thaisrivongs, Timothy Chamberlain, J. Perry Hall, Julie Liu, Michael Luong, Lih‐Ling Lin, Jean‐Baptiste Telliez, Ariamala Gopalsamy	2011	17
7	Identification and Characterization of Acidic Mammalian Chitinase Inhibitors Journal of Medicinal Chemistry ·Derek C. Cole, Andrea Olland, Jaison Jacob, J.C. Brooks, Matthew G. Bursavich, Robert Czerwiński, Charlene DeClercq, M. Catherine Johnson, Diane Joseph‐McCarthy, John W. Ellingboe, Laura Lin, Paweł Nowak, Ella Presman, James C. Strand, Amy Tam, Cara Williams, Shihua Yao, Désirée H.H. Tsao, Lori Fitz	2010	30
8	Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin Cancer Research ·Ker Yu, Lourdes Toral‐Barza, Celine Shi, Weiguo Zhang, Judy Lucas, Boris Shor, Jamie Kim, Jeroen C. Verheijen, Kevin J. Curran, David J. Malwitz, Derek C. Cole, John W. Ellingboe, Semiramis Ayral‐Kaloustian, Tarek S. Mansour, James J. Gibbons, Robert T. Abraham, Paweł Nowak, Arie Zask	2009	277
9	Identification of a new class of small molecule C5a receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Jack J. Chen, Derek C. Cole, Greg Ciszewski, Kimberly Crouse, John W. Ellingboe, Paweł Nowak, Gregory J. Tawa, Gabriel Berstein, Wei Li	2009	5
10	Synthesis and PKCθ inhibitory activity of a series of 4-indolylamino-5-phenyl-3-pyridinecarbonitriles Bioorganic & Medicinal Chemistry Letters ·Russell G. Dushin, Thomas Nittoli, Charles L. Ingalls, Diane H. Boschelli, Derek C. Cole, Allan Wissner, Julie Lee, Xiaoke Yang, Paul Morgan, Agnes Brennan, Divya Chaudhary	2009	20
11	Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonists Bioorganic & Medicinal Chemistry ·Ronald C. Bernotas, Steven Lenicek, Schuyler Antane, Derek C. Cole, Boyd L. Harrison, Albert J. Robichaud, Guo Ming Zhang, Deborah L. Smith, Brian J. Platt, Qian Lin, Ping Li, Joseph Coupet, Sharon Rosenzweig‐Lipson, Chad E. Beyer, Lee E. Schechter	2009	15
12	A fluorescent assay suitable for inhibitor screening and vanin tissue quantification Analytical Biochemistry ·Benfang Helen Ruan, Derek C. Cole, Paul W. Wu, Amira Quazi, Karen Page, Jill F. Wright, Nelson Huang, Joseph R. Stock, Karl Nocka, Ann Aulabaugh, Rustem Krykbaev, Lori Fitz, Neil M. Wolfman, Margaret L. Fleming	2009	41
13	Synthesis and PKCθ inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles Bioorganic & Medicinal Chemistry Letters ·Diane H. Boschelli, Biqi Wu, Ana Carolina Barrios Sosa, Joan Chen, Magda Asselin, Derek C. Cole, Julie Lee, Xiaoke Yang, Divya Chaudhary	2008	31
14	A FLIPR-Based Assay to Assess Potency and Selectivity of Inhibitors of the TEC Family Kinases Btk and Itk Assay and Drug Development Technologies ·John Douhan, Joy Miyashiro, Xiaochuan Zhou, Derek C. Cole, Paul W. Wu, Mary Collins, Kyriaki Dunussi‐Joannopoulos	2007	5
15	Neuropharmacological Profile of Novel and Selective 5-HT6 Receptor Agonists: WAY-181187 and WAY-208466 Neuropsychopharmacology ·Lee E. Schechter, Qian Lin, Deborah L. Smith, Guoming Zhang, Qin Shan, Brian J. Platt, Michael R. Brandt, Lee A. Dawson, Derek C. Cole, Ron Bernotas, Albert J. Robichaud, Sharon Rosenzweig‐Lipson, Chad E. Beyer	2007	176
16	Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Derek C. Cole, William J. Lennox, Joseph R. Stock, John W. Ellingboe, Hossein Mazandarani, Deborah L. Smith, Guoming Zhang, Gregory J. Tawa, Lee E. Schechter	2005	28
17	N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Derek C. Cole, John W. Ellingboe, William J. Lennox, Hossein Mazandarani, Deborah L. Smith, Joseph R. Stock, Guoming Zhang, Ping Zhou, Lee E. Schechter	2004	37
18	Use of Design of Experiments To Optimize High-Throughput Semipreparative LC and LC/MS Methods Journal of Combinatorial Chemistry ·Derek C. Cole, N. J. Pagano, Michael F. Kelly, John W. Ellingboe	2003	15
19	Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide Bioorganic & Medicinal Chemistry Letters ·Derek C. Cole, Joseph R. Stock, Jo Anne Kappel	2002	14
20	Use of .beta.-Methylphenylalanine (.beta.MeF) Residues To Probe the Nature of the Interaction of Substance P with Its Receptor: Effects of .beta.MeF-Containing Substance P Analogs on Rabbit Iris Smooth Muscle Contraction Journal of Medicinal Chemistry ·David M. Birney, Derek C. Cole, Craig E. Crosson, Brenda F. Kahl, Bart W. Neff, Ted W. Reid, Kaijun Ren, Robert D. Walkup	1995	9

About Derek C. Cole

Derek C. Cole is a scholar working on Organic Chemistry, Molecular Biology, Cellular and Molecular Neuroscience, Microbiology and Toxicology, having authored 39 papers that have together received 1.9k indexed citations. Recurring topics across this work include Synthesis and biological activity (7 papers), Protein Kinase Regulation and GTPase Signaling (6 papers), Receptor Mechanisms and Signaling (5 papers), Chemical Synthesis and Analysis (5 papers), Peptidase Inhibition and Analysis (4 papers), Computational Drug Discovery Methods (4 papers), Redox biology and oxidative stress (3 papers) and Synthesis and Reactivity of Heterocycles (3 papers). The work is most often cited by research in Organic Chemistry (908 citations), Molecular Biology (1.1k citations), Cellular and Molecular Neuroscience (272 citations), Pharmacology (141 citations) and Inorganic Chemistry (111 citations). Derek C. Cole has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include John W. Ellingboe, Deborah L. Smith, Lee E. Schechter, Paul Jackson, Barbara S. Slusher, Diane A. Trainor, Bruce A. Donzanti, Paweł Nowak, James J. Gibbons and Guoming Zhang. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, The Journal of Organic Chemistry, Journal of the American Chemical Society and ACS Medicinal Chemistry Letters.

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