Ronald A. DePinho

902 total papers · 128.9k total citations
417 papers, 86.0k citations indexed

About

Ronald A. DePinho is a scholar working on Molecular Biology, Oncology and Physiology. According to data from OpenAlex, Ronald A. DePinho has authored 417 papers receiving a total of 86.0k indexed citations (citations by other indexed papers that have themselves been cited), including 284 papers in Molecular Biology, 133 papers in Oncology and 87 papers in Physiology. Recurrent topics in Ronald A. DePinho's work include Telomeres, Telomerase, and Senescence (66 papers), FOXO transcription factor regulation (63 papers) and Cancer-related Molecular Pathways (61 papers). Ronald A. DePinho is often cited by papers focused on Telomeres, Telomerase, and Senescence (66 papers), FOXO transcription factor regulation (63 papers) and Cancer-related Molecular Pathways (61 papers). Ronald A. DePinho collaborates with scholars based in United States, Australia and South Korea. Ronald A. DePinho's co-authors include Nabeel Bardeesy, Lynda Chin, Norman E. Sharpless, James W. Horner, Han‐Woong Lee, Paraskevi A. Farazi, Carol W. Greider, Frederick W. Alt, Lewis C. Cantley and Diego H. Castrillón and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ronald A. DePinho

413 papers receiving 84.6k citations

Hit Papers

Malignant astrocytic glio... 1991 2026 2002 2014 2007 1997 1991 2006 2005 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation benchmark for papers published in the same subfield and year, or reaches the top citation threshold in at least one of its specific research topics.

  1. Malignant astrocytic glioma: genetics, biology, and paths to treatment
    2007 1.8k citations Frank B. Furnari, Tim R. Fenton et al. Genes & Development profile →
  2. Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
    1997 1.7k citations Marı́a A. Blasco, Han‐Woong Lee et al. Cell profile →
  3. ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
    1991 1.7k citations Teri G. Boulton, Steven H. Nye et al. Cell profile →
  4. Hepatocellular carcinoma pathogenesis: from genes to environment
    2006 1.6k citations Paraskevi A. Farazi, Ronald A. DePinho Nature reviews. Cancer profile →
  5. The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
    2005 1.6k citations Reuben J. Shaw, Nabeel Bardeesy et al. Science profile →
  6. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
    2004 1.5k citations Reuben J. Shaw, Nabeel Bardeesy et al. Proceedings of the National Academy of Sciences profile →
  7. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
    2013 1.5k citations Jaekyoung Son, Costas A. Lyssiotis et al. Nature profile →
  8. Role of the INK4a Locus in Tumor Suppression and Cell Mortality
    1996 1.3k citations Manuel Serrano, Han‐Woong Lee et al. Cell profile →
  9. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    1999 1.3k citations Jacqueline J.L. Jacobs, Silvia Marino et al. Nature profile →
  10. HDAC2 negatively regulates memory formation and synaptic plasticity
    2009 1.3k citations Ji‐Song Guan, Stephen J. Haggarty et al. Nature profile →
  11. The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53
    1998 1.2k citations Jason H. Pomerantz, Nicole Schreiber‐Agus et al. Cell profile →
  12. FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress
    2007 1.2k citations Zuzana Tóthová, Ramya Kollipara et al. Cell profile →
  13. Genetics and biology of pancreatic ductal adenocarcinoma
    2006 1.2k citations Aram F. Hezel, Alec C. Kimmelman et al. Genes & Development profile →
  14. Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
    1999 1.1k citations K. Lenhard Rudolph, Sandy Chang et al. Cell profile →
  15. Essential role of mouse telomerase in highly proliferative organs
    1998 1.0k citations Han‐Woong Lee, Marı́a A. Blasco et al. Nature profile →
  16. Malignant glioma: genetics and biology of a grave matter
    2001 986 citations Elizabeth A. Maher, Frank B. Furnari et al. Genes & Development profile →
  17. Pancreatic cancer biology and genetics
    2002 886 citations Nabeel Bardeesy, Ronald A. DePinho Nature reviews. Cancer profile →
  18. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    2000 873 citations Maja Artandi, Sandy Chang et al. Nature profile →
  19. The LKB1 tumor suppressor negatively regulates mTOR signaling
    2004 871 citations Reuben J. Shaw, Nabeel Bardeesy et al. Cancer Cell profile →
  20. FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis
    2007 859 citations Ji-Hye Paik, Ramya Kollipara et al. Cell profile →
  21. Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism
    2010 859 citations Mathieu Ferron, Jianwen Wei et al. Cell profile →
  22. BrafV600E cooperates with Pten loss to induce metastatic melanoma
    2009 833 citations David Dankort, David P. Curley et al. Nature Genetics profile →
  23. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
    2006 817 citations Viktor Janzen, Randolf Forkert et al. Nature profile →
  24. p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
    1999 778 citations Lynda Chin, Steven E. Artandi et al. Cell profile →
  25. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
    2003 762 citations Andrew J. Aguirre, Nabeel Bardeesy et al. Genes & Development profile →
  26. Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a
    2003 740 citations Diego H. Castrillón, Lili Miao et al. Science profile →
  27. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
    1997 728 citations Rebecca Muhle, Harry Hou et al. Nature profile →
  28. The age of cancer
    2000 719 citations Ronald A. DePinho Nature profile →
  29. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
    2007 699 citations Jayne M. Stommel, Alec C. Kimmelman et al. Science profile →
  30. Essential role for oncogenic Ras in tumour maintenance
    1999 698 citations Lynda Chin, Jason H. Pomerantz et al. Nature profile →
  31. Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
    2001 661 citations Norman E. Sharpless, Nabeel Bardeesy et al. Nature profile →
  32. How stem cells age and why this makes us grow old
    2007 639 citations Norman E. Sharpless, Ronald A. DePinho Nature Reviews Molecular Cell Biology profile →
  33. Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects
    2004 625 citations David A. Tuveson, Alice T. Shaw et al. Cancer Cell profile →
  34. Cellular Senescence
    2000 622 citations Charles J. Sherr, Ronald A. DePinho Cell profile →
  35. Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome
    1997 617 citations Pumin Zhang, Nanette J. Liégeois et al. Nature profile →
  36. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
    2010 597 citations Mariela Jaskelioff, Florian L. Müller et al. Nature profile →
  37. Telomeres and telomerase in cancer
    2009 590 citations Steven E. Artandi, Ronald A. DePinho Carcinogenesis profile →
  38. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
    2008 574 citations Hongwu Zheng, Haoqiang Ying et al. Nature profile →
  39. Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
    2010 570 citations Nirmala Hariharan, Yasuhiro Maejima et al. Circulation Research profile →
  40. Linking functional decline of telomeres, mitochondria and stem cells during ageing
    2010 547 citations Ergün Sahin, Ronald A. DePinho Nature profile →
  41. SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
    2011 536 citations Hiroyuki Inuzuka, Shavali Shaik et al. Nature profile →
  42. Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy
    2015 529 citations Giulia Milan, Vanina Romanello et al. Nature Communications profile →
  43. Genetics and biology of prostate cancer
    2018 516 citations Guocan Wang, Di Zhao et al. Genes & Development profile →
  44. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    1994 509 citations Sharon D. Morgenbesser, Bart O. Williams et al. Nature profile →
  45. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
    2006 505 citations Nabeel Bardeesy, Kuang‐Hung Cheng et al. Genes & Development profile →
  46. Epidermal growth factor receptor and Ink4a/Arf
    2002 501 citations Robert Bachoo, Elizabeth A. Maher et al. Cancer Cell profile →
  47. Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
    2007 500 citations Michihiro Matsumoto, Alessandro Pocai et al. Cell Metabolism profile →
  48. Emerging insights into the molecular and cellular basis of glioblastoma
    2012 423 citations Gavin P. Dunn, Mikael L. Rinne et al. Genes & Development profile →
  49. Effective combinatorial immunotherapy for castration-resistant prostate cancer
    2017 396 citations Xin Lü, James W. Horner et al. Nature profile →
  50. Telomeres: history, health, and hallmarks of aging
    2021 383 citations Deepavali Chakravarti, Kyle A. LaBella et al. Cell profile →
  51. Genetic and biological hallmarks of colorectal cancer
    2021 311 citations Jiexi Li, Xingdi Ma et al. Genes & Development profile →
  52. Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
    1999 307 citations Roger A. Greenberg, Lynda Chin et al. Cell profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Ronald A. DePinho 55.9k 23.0k 16.5k 13.7k 9.8k 417 86.0k
George D. Yancopoulos 55.1k 1.0× 14.3k 0.6× 12.2k 0.7× 11.9k 0.9× 15.9k 1.6× 430 102.8k
Harvey F. Lodish 49.1k 0.9× 9.4k 0.4× 15.7k 1.0× 11.2k 0.8× 8.7k 0.9× 645 82.0k
Roderick T. Bronson 46.0k 0.8× 23.1k 1.0× 5.8k 0.3× 11.6k 0.8× 11.5k 1.2× 544 77.7k
Kari Alitalo 56.7k 1.0× 45.4k 2.0× 10.9k 0.7× 12.4k 0.9× 8.3k 0.8× 717 94.2k
Peter Carmeliet 53.0k 0.9× 15.0k 0.7× 6.4k 0.4× 27.4k 2.0× 11.7k 1.2× 730 99.7k
Roger J. Davis 62.4k 1.1× 15.6k 0.7× 8.3k 0.5× 11.6k 0.8× 13.6k 1.4× 570 92.5k
David M. Sabatini 71.4k 1.3× 9.5k 0.4× 11.3k 0.7× 12.8k 0.9× 10.4k 1.1× 256 100.6k
Scott W. Lowe 50.1k 0.9× 22.9k 1.0× 6.6k 0.4× 16.9k 1.2× 8.5k 0.9× 325 69.4k
Lewis C. Cantley 104.9k 1.9× 27.4k 1.2× 11.7k 0.7× 29.7k 2.2× 16.8k 1.7× 708 150.1k
John C. Reed 73.3k 1.3× 21.4k 0.9× 4.6k 0.3× 12.2k 0.9× 20.4k 2.1× 797 107.4k

Countries citing papers authored by Ronald A. DePinho

Since Specialization
Citations

This map shows the geographic impact of Ronald A. DePinho's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ronald A. DePinho with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ronald A. DePinho more than expected).

Fields of papers citing papers by Ronald A. DePinho

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ronald A. DePinho. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ronald A. DePinho. The network helps show where Ronald A. DePinho may publish in the future.

Co-authorship network of co-authors of Ronald A. DePinho

This figure shows the co-authorship network connecting the top 25 collaborators of Ronald A. DePinho. A scholar is included among the top collaborators of Ronald A. DePinho based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ronald A. DePinho. Ronald A. DePinho is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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