Aaron D. Schuler

1.2k citations

17 papers · 975 indexed · h-index 11

Impact in

Geriatrics and Gerontology top 1%
- Sirtuins and Resveratrol in Medicine
Physiology top 2%
- Calcium signaling and nucleotide metabolism

Papers in

Geriatrics and Gerontology 2
- Sirtuins and Resveratrol in Medicine 2
Small Animals 2
- Veterinary Pharmacology and Anesthesia 2

Co-authors: Julian A. Simon Jeff Posakony Antonio Bedalov Barry Stoddard Alex N. Bullock Tanja Kortemme Łukasz A. Joachimiak David Baker
Journals: Bioorganic & Medicinal Chemistry Letters (2 papers)Journal of Medicinal Chemistry (2 papers)Journal of Pharmacology and Experimental Therapeutics (1 paper)Journal of Pain (1 paper)Nature Structural & Molecular Biology (1 paper)
Partner nations: United States South Africa Austria

In The Last Decade

Aaron D. Schuler

17 papers receiving 960 citations

Peers

Countries citing papers authored by Aaron D. Schuler

Since Specialization

Citations

This map shows the geographic impact of Aaron D. Schuler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aaron D. Schuler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aaron D. Schuler more than expected).

Fields of papers citing papers by Aaron D. Schuler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aaron D. Schuler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aaron D. Schuler. The network helps show where Aaron D. Schuler may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Aaron D. Schuler, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Aaron D. Schuler Line = papers co-authored together Aaron D. Schuler links everyone, so they are left out of the graph.

All Works

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17 of 17 papers shown

#	Work
1	Safety and efficacy of first-in-class CXCR1/2 inhibitor SX-682 in combination with pembrolizumab (pem) in patients (pts) with metastatic melanoma (mMEL) with disease progression on anti–PD-1 therapy. Journal of Clinical Oncology ·Sapna P. Patel, Anastasios Dimou, Adrienne I. Victor, Meghan J. Mooradian, Elizabeth I. Buchbinder, Leonel F. Hernandez‐Aya, Peter A. Prieto, Justine V. Cohen, Keith T. Flaherty, Stuart J. Kahn, Aaron D. Schuler, Dean Y. Maeda, John A. Zebala	2024	10
2	Phase 1 Results of the First-in-Class CXCR1/2 Inhibitor SX-682 in Patients with Hypomethylating Agent Failure Myelodysplastic Syndromes Blood ·David A. Sallman, Amy E. DeZern, Arlene A. Gayle, Stuart J. Kahn, Eric Padron, Jeffrey E. Lancet, Andrew Kuykendall, Kendra Sweet, Onyee Chan, Dean Y. Maeda, Aaron D. Schuler, John A. Zebala, Rami S. Komrokji	2022	11
3	Desmetramadol Is Identified as a G-Protein Biased µ Opioid Receptor Agonist Frontiers in Pharmacology ·John A. Zebala, Aaron D. Schuler, Stuart J. Kahn, Dean Y. Maeda	2020	12
4	Desmetramadol Has the Safety and Analgesic Profile of Tramadol Without Its Metabolic Liabilities: Consecutive Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Trials Journal of Pain ·John A. Zebala, 朱晓林, Lynn R. Webster, I Goos, Aaron D. Schuler, Dean Y. Maeda, Stuart J. Kahn	2019	9
5	Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model Bioorganic & Medicinal Chemistry Letters ·Dean Y. Maeda, Farhana Chaiti, Aaron D. Schuler, Mark T. Quinn, Liliya N. Kirpotina, W.N. Wicomb, Richard L. Auten, Rambabu Gundla, John A. Zebala	2015	12
6	Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailability Bioorganic & Medicinal Chemistry Letters ·Aaron D. Schuler, Erin Stokes, Dean Y. Maeda, Mark T. Quinn, Liliya N. Kirpotina, W.N. Wicomb, S. Nicholas Mason, Richard L. Auten, John A. Zebala	2015	12
7	LD-Aminopterin in the Canine Homologue of Human Atopic Dermatitis: A Randomized, Controlled Trial Reveals Dosing Factors Affecting Optimal Therapy PLoS ONE ·John A. Zebala, James Wayne Mitchell, A G Jiménez, Craig E. Griffin, Aaron D. Schuler, Stuart J. Kahn	2014	2
8	Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2 Journal of Medicinal Chemistry ·Dean Y. Maeda, Farhana Chaiti, Aaron D. Schuler, Mark T. Quinn, Liliya N. Kirpotina, W.N. Wicomb, Mitsuhiko Odera, John A. Zebala	2014	29
9	Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors Journal of Medicinal Chemistry ·Sumit Mahajan, Michele Scian, Smitha Sripathy, Jeff Posakony, Uyen Lao, Taylor K. Loe, Vid Leko, Gouda Takuya, Aaron D. Schuler, Antonio Bedalov, Julian A. Simon	2014	110
10	Intestinal Transport of Aminopterin Enantiomers in Dogs and Humans with Psoriasis Is Stereoselective: Evidence for a Mechanism Involving the Proton-Coupled Folate Transporter Journal of Pharmacology and Experimental Therapeutics ·Alan Menter, 刘兴柱, Christina Cherian, Larry H. Matherly, Lei Wang, Aleem Gangjee, Mekete Desse, Dean Y. Maeda, Aaron D. Schuler, Stuart J. Kahn, John A. Zebala	2012	15
11	Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain Bioorganic Chemistry ·Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Mekete Desse, Reni Dahar, Kezhen Huang, Gongqin Sun, John A. Zebala, Keykavous Parang	2009	3
12	PhotoMorphs™: A novel light‐activated reagent for controlling gene expression in zebrafish genesis ·S. V. Meshcherov, Aaron D. Schuler, John A. Zebala, Alan N. Mayer	2009	51
13	Antitumor Activity of a Small-Molecule Inhibitor of Human Silent Information Regulator 2 Enzymes Cancer Research ·Birgit Heltweg, Tonibelle Gatbonton, Aaron D. Schuler, Jeff Posakony, Hongzhe Li, Sondra Goehle, Ramya Kollipara, Ronald A. DePinho, Yansong Gu, Julian A. Simon, Antonio Bedalov	2006	400
14	KN-62 analogues as potent differentiating agents of HL-60 cells Leukemia Research ·Aaron D. Schuler, Jutong Si, LeMoyne Mueller, Julian A. Simon, Steven Collins	2006	3
15	Computational redesign of protein-protein interaction specificity Nature Structural & Molecular Biology ·Tanja Kortemme, Łukasz A. Joachimiak, Alex N. Bullock, Aaron D. Schuler, Barry Stoddard, David Baker	2004	244
16	Determination of molecules regulating gene delivery using adenoviral vectors in ovarian carcinomas Gene Therapy ·L. Carmans, Elisabeth Müller‐Holzner, Aaron D. Schuler, G. Hartung, Jennifer Berger, Martin Hermann, Martin Widschwendter, 邹先定, Christian Marth	2002	46
17	Synthesis, reactivity and structural study of diastereomeric titanium complexes with amino acid derived N- and O-π donor ligands Inorganica Chimica Acta ·G L Sannazzari, Aaron D. Schuler, Mirzakhmedova Dilfuza, Steven R. Herron, Katherine A. Kantardjieff, Adam R. Johnson	2002	6

About Aaron D. Schuler

Aaron D. Schuler is a scholar working on Geriatrics and Gerontology, Small Animals, Hematology, Oncology and Physiology, having authored 17 papers that have together received 975 indexed citations. Recurring topics across this work include Chemokine receptors and signaling (5 papers), Acute Myeloid Leukemia Research (2 papers), Sirtuins and Resveratrol in Medicine (2 papers), Veterinary Pharmacology and Anesthesia (2 papers), Immune Response and Inflammation (2 papers), Histone Deacetylase Inhibitors Research (2 papers), Cytokine Signaling Pathways and Interactions (2 papers) and Amino Acid Enzymes and Metabolism (1 paper). The work is most often cited by research in Geriatrics and Gerontology (356 citations), Physiology (114 citations), Molecular Biology (552 citations), Oncology (192 citations) and Epidemiology (210 citations). Aaron D. Schuler has collaborated with scholars based in United States, South Africa and Austria. Frequent co-authors include Julian A. Simon, Jeff Posakony, Antonio Bedalov, Barry Stoddard, Alex N. Bullock, Tanja Kortemme, Łukasz A. Joachimiak, David Baker, Ramya Kollipara and Birgit Heltweg. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics, Journal of Pain and Nature Structural & Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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