Lynda Chin

117.2k citations

160 papers · 29.4k indexed · 15 hit papers · h-index 82

Molecular Biology top 0.05%
Oncology top 0.1%
Cancer Research top 0.05%
Physiology top 0.2%
Cell Biology top 0.2%

Co-authors: Ronald A. DePinho Cameron Brennan Levi A. Garraway Carlos Cordon‐Cardo Han‐Woong Lee P. Andrew Futreal Keith L. Ligon Alexei Protopopov
Topics: Melanoma and MAPK Pathways (29 papers)Cancer Genomics and Diagnostics (27 papers)Cancer-related Molecular Pathways (16 papers)
Cited by: Aging Cancer Research Oncology
Journals: Nature Science Cell
Partner nations: United States Brazil United Kingdom

In The Last Decade

Lynda Chin

158 papers receiving 28.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Malignant astrocytic glioma: genetics, biology, and paths to treatment

2007 1.8k citations Jayne M. Stommel, Alexander H. Stegh et al. Genes & Development profile →
Role of the INK4a Locus in Tumor Suppression and Cell Mortality

1996 1.3k citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Highly Recurrent TERT Promoter Mutations in Human Melanoma

2013 1.3k citations Lynda Chin, Levi A. Garraway et al. Science profile →
The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

1998 1.2k citations Nicole Schreiber‐Agus, Leila Alland et al. Cell profile →
Molecular characterization of the tumor microenvironment in breast cancer

2004 1.0k citations Cameron Brennan, Lynda Chin et al. profile →
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

2000 873 citations Lynda Chin, Ronald A. DePinho et al. profile →
FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis

2007 859 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Identification of Double-stranded Genomic DNA Spanning All Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer

2014 810 citations Alexei Protopopov, Jianhua Zhang et al. profile →
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis

1999 779 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 728 citations Lynda Chin, Nicole Schreiber‐Agus et al. profile →
Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies

2007 699 citations Jayne M. Stommel, Alec C. Kimmelman et al. Science profile →
Essential role for oncogenic Ras in tumour maintenance

1999 697 citations Lynda Chin, Ronald A. DePinho et al. profile →
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

2008 573 citations Haoqiang Ying, Alec C. Kimmelman et al. profile →
Emerging insights into the molecular and cellular basis of glioblastoma

2012 425 citations Giannicola Genovese, Cameron Brennan et al. Genes & Development profile →
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse

1999 307 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →

Peers

Countries citing papers authored by Lynda Chin

Since Specialization

Citations

This map shows the geographic impact of Lynda Chin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lynda Chin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lynda Chin more than expected).

Fields of papers citing papers by Lynda Chin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lynda Chin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lynda Chin. The network helps show where Lynda Chin may publish in the future.

Co-authorship network of co-authors of Lynda Chin

This figure shows the co-authorship network connecting the top 25 collaborators of Lynda Chin. A scholar is included among the top collaborators of Lynda Chin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lynda Chin. Lynda Chin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Chromosome 10, Frequently Lost in Human Melanoma, Encodes Multiple Tumor-Suppressive Functions 2014 ·Cancer Research ·Lawrence N. Kwong,Lynda Chin	16
2	The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF 2014 ·Cancer Research ·Ian R. Watson,Li Li,(unknown),(unknown),Tony Gutschner,Giannicola Genovese,Guocan Wang,Zhuangna Fang,James M. Tepper,Katherine Stemke‐Hale,Kenneth Y. Tsai,Michael A. Davies,Gordon B. Mills,Lynda Chin	116
3	Polygenic in vivovalidation of cancer mutations using transposons 2014 ·Genome biology ·Su Kit Chew,Dong Lu,Lia S. Campos,Kenneth L. Scott,Abdel Saci,Juexuan Wang,(unknown),Keiran Raine,Jonathan Hinton,Jon W. Teague,David Jones,Andrew Menzies,Adam P. Butler,John Gamble,Sarah O’Meara,Stuart McLaren,Lynda Chin,Pentao Liu,P. Andrew Futreal	3
4	Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes 2014 ·Cell ·Lixing Yang,Lovelace J. Luquette,Nils Gehlenborg,Ruibin Xi,Psalm Haseley,(unknown),Chengsheng Zhang,Xiaojia Ren,Alexei Protopopov,Lynda Chin,Raju Kucherlapati,Charles Lee,Peter J. Park	7
5	Double Minute Chromosomes in Glioblastoma Multiforme Are Revealed by Precise Reconstruction of Oncogenic Amplicons 2013 ·Cancer Research ·Zack Sanborn,Sofie R. Salama,Mia Grifford,Cameron Brennan,Tom Mikkelsen,Suresh C. Jhanwar,Sol Katzman,Lynda Chin,David Haussler	73
6	Absence of Biallelic TCR γ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia 2010 ·Journal of Clinical Oncology ·Alejandro Gutiérrez,Suzanne E. Dahlberg,Donna Neuberg,Jianhua Zhang,Ruta Grebliunaite,Takaomi Sanda,Alexei Protopopov,Valeria Tosello,Jeffery L. Kutok,Richard A. Larson,Michael J. Borowitz,Mignon L. Loh,Adolfo A. Ferrando,Stuart S. Winter,Charles G. Mullighan,Lewis B. Silverman,Lynda Chin,Stephen P. Hunger,Stephen E. Sallan,A. Thomas Look	69
7	Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling 2008 ·Genes & Development ·Hye-Min Jeon,Xun Jin,(unknown),Se-Yeong Oh,(unknown),Hyo‐Jung Park,Kyeung Min Joo,Woong‐Yang Park,Do‐Hyun Nam,Ronald A. DePinho,Lynda Chin,Hyunggee Kim	101
8	A Comparison of DNA Copy Number Profiling Platforms 2007 ·Cancer Research ·Joel Greshock,Bin Feng,Cristina Nogueira,Elena V. Ivanova,Ilana Perna,Katherine L. Nathanson,Alexei Protopopov,Barbara Weber,Lynda Chin	54
9	Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models 2007 ·Cancer Research ·Hongbin Ji,Zhenxiong Wang,Samanthi A. Perera,Danan Li,Mei‐Chih Liang,Sara Zaghlul,Kate McNamara,Liang Chen,Mitchell Albert,Yanping Sun,Ruqayyah Al-Hashem,Lucian R. Chirieac,Robert F. Padera,Roderick T. Bronson,Roman K. Thomas,Levi A. Garraway,Pasi A. Jänne,Bruce E. Johnson,Lynda Chin,Kwok‐Kin Wong	137
10	An X Chromosome Gene, WTX , Is Commonly Inactivated in Wilms Tumor 2007 ·Science ·Miguel N. Rivera,Woo‐Jae Kim,Julie Wells,David R. Driscoll,Brian W. Brannigan,Moonjoo Han,James C. Kim,Andrew P. Feinberg,William L. Gerald,Sara O. Vargas,Lynda Chin,A. John Iafrate,Daphne W. Bell,Daniel A. Haber	225
11	Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapiesbreakdown → 2007 ·Science ·Jayne M. Stommel,Alec C. Kimmelman,Haoqiang Ying,Roustem Nabioullin,(unknown),Ruprecht Wiedemeyer,Alexander H. Stegh,James E. Bradner,Keith L. Ligon,Cameron Brennan,Lynda Chin,Ronald A. DePinho	699
12	Direct Transcriptional Activation of Promyelocytic Leukemia Protein by IFN Regulatory Factor 3 Induces the p53-Dependent Growth Inhibition of Cancer Cells 2007 ·Cancer Research ·(unknown),(unknown),Se-Yeong Oh,Xun Jin,Yun‐Jaie Choi,Tae‐Hoon Lee,(unknown),Young Ki Choi,Seungkwon You,Yong Gu Chung,Jang-Bo Lee,Ronald A. DePinho,Lynda Chin,Hyunggee Kim	38
13	Common and Distinct Genomic Events in Sporadic Colorectal Cancer and Diverse Cancer Types 2007 ·Cancer Research ·Eric S. Martin,Giovanni Tonon,Raktim Sinha,Yonghong Xiao,Bin Feng,Alec C. Kimmelman,Alexei Protopopov,Elena V. Ivanova,Cameron Brennan,Kate Montgomery,Raju Kucherlapati,Gerald Bailey,Mark Redston,Lynda Chin,Ronald A. DePinho	54
14	Frequent Met Oncogene Amplification in a Brca1/Trp53 Mouse Model of Mammary Tumorigenesis 2006 ·Cancer Research ·Gromoslaw A. Smolen,Beth Muir,Gayatry Mohapatra,Anne Barmettler,Woo Jae Kim,Miguel N. Rivera,Sara M. Haserlat,Ross A. Okimoto,Eunice L. Kwak,Sonika Dahiya,Judy E. Garber,Daphne W. Bell,Dennis C. Sgroi,Lynda Chin,Chu‐Xia Deng,Daniel A. Haber	32
15	A Genome-Wide Screen Reveals Functional Gene Clusters in the Cancer Genome and Identifies EphA2 as a Mitogen in Glioblastoma 2006 ·Cancer Research ·Fenghua Liu,Peter J. Park,Weil Lai,Elizabeth A. Maher,Arnab Chakravarti,Laura Durso,Xiuli Jiang,(unknown),(unknown),Meredith Thomas,Lynda Chin,Cameron Brennan,Ronald A. DePinho,Isaac S. Kohane,Rona S. Carroll,Peter McL. Black,Mark D. Johnson	94
16	Marked Genomic Differences Characterize Primary and Secondary Glioblastoma Subtypes and Identify Two Distinct Molecular and Clinical Secondary Glioblastoma Entities 2006 ·Cancer Research ·Elizabeth A. Maher,Cameron Brennan,Patrick Y. Wen,Laura Durso,Keith L. Ligon,Aaron Richardson,Deepak Khatry,Bin Feng,Raktim Sinha,David N. Louis,John Quackenbush,Peter McL. Black,Lynda Chin,Ronald A. DePinho	140
17	High-Resolution Global Profiling of Genomic Alterations with Long Oligonucleotide Microarray 2004 ·Cancer Research ·Cameron Brennan,Yunyu Zhang,Christopher Leo,Bin Feng,(unknown),Andrew J. Aguirre,Minjung Kim,Alexei Protopopov,Lynda Chin	101
18	Genetic dissection of melanoma pathways in the mouse 2001 ·Seminars in Cancer Biology ·Fan Yang,Glenn Merlino,Lynda Chin	17
19	Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1. 1996 ·PubMed ·Govinda Rao,Leila Alland,Peter Guida,Nicole Schreiber‐Agus,Ken Chen,Lynda Chin,Julie M. Rochelle,Michael F. Seldin,Arthur I. Skoultchi,Ronald A. DePinho	36
20	Evolutionary relationships and functional conservation among vertebrate Max-associated proteins: the zebra fish homolog of Mxi1. 1994 ·PubMed ·Nicole Schreiber‐Agus,Lynda Chin,Ken Chen,Richard Torres,Cole T. Thomson,James C. Sacchettini,Ronald A. DePinho	25

About Lynda Chin

Lynda Chin is a scholar working on Aging, Cancer Research and Molecular Biology, having authored 160 papers that have together received 29.4k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (29 papers), Cancer Genomics and Diagnostics (27 papers) and Cancer-related Molecular Pathways (16 papers). The work is most often cited by research in Aging (934 citations), Cancer Research (6.7k citations) and Oncology (9.3k citations). Lynda Chin has collaborated with scholars based in United States, Brazil and United Kingdom. Frequent co-authors include Ronald A. DePinho, Cameron Brennan, Levi A. Garraway, Carlos Cordon‐Cardo, Han‐Woong Lee, P. Andrew Futreal, Keith L. Ligon, Alexei Protopopov, Geoffrey J. Gottlieb and William C. Hahn. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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