Lynda Chin

117.2k total citations · 15 hit papers
160 papers, 29.4k citations indexed

About

Lynda Chin is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Lynda Chin has authored 160 papers receiving a total of 29.4k indexed citations (citations by other indexed papers that have themselves been cited), including 126 papers in Molecular Biology, 47 papers in Oncology and 41 papers in Cancer Research. Recurrent topics in Lynda Chin's work include Melanoma and MAPK Pathways (29 papers), Cancer Genomics and Diagnostics (27 papers) and Cancer-related Molecular Pathways (16 papers). Lynda Chin is often cited by papers focused on Melanoma and MAPK Pathways (29 papers), Cancer Genomics and Diagnostics (27 papers) and Cancer-related Molecular Pathways (16 papers). Lynda Chin collaborates with scholars based in United States, Brazil and United Kingdom. Lynda Chin's co-authors include Ronald A. DePinho, Cameron Brennan, Levi A. Garraway, Carlos Cordon‐Cardo, Han‐Woong Lee, P. Andrew Futreal, Keith L. Ligon, Alexei Protopopov, Geoffrey J. Gottlieb and William C. Hahn and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Lynda Chin

158 papers receiving 28.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Malignant astrocytic glioma: genetics, biology, and paths to treatment

2007 1.8k citations Jayne M. Stommel, Alexander H. Stegh et al. Genes & Development profile →
Role of the INK4a Locus in Tumor Suppression and Cell Mortality

1996 1.3k citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Highly Recurrent TERT Promoter Mutations in Human Melanoma

2013 1.3k citations Lynda Chin, Levi A. Garraway et al. Science profile →
The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

1998 1.2k citations Nicole Schreiber‐Agus, Leila Alland et al. Cell profile →
Molecular characterization of the tumor microenvironment in breast cancer

2004 1.0k citations Cameron Brennan, Lynda Chin et al. profile →
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

2000 873 citations Lynda Chin, Ronald A. DePinho et al. Nature profile →
FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis

2007 859 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Identification of Double-stranded Genomic DNA Spanning All Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer

2014 810 citations Alexei Protopopov, Jianhua Zhang et al. profile →
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis

1999 779 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 728 citations Rebecca Muhle, Harry Hou et al. Nature profile →
Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies

2007 699 citations Jayne M. Stommel, Alec C. Kimmelman et al. Science profile →
Essential role for oncogenic Ras in tumour maintenance

1999 697 citations Lynda Chin, Ronald A. DePinho et al. Nature profile →
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

2008 573 citations Haoqiang Ying, Alec C. Kimmelman et al. Nature profile →
Emerging insights into the molecular and cellular basis of glioblastoma

2012 425 citations Giannicola Genovese, Cameron Brennan et al. Genes & Development profile →
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse

1999 307 citations Lynda Chin, Ronald A. DePinho et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lynda Chin United States	82	20.4k	9.3k	6.7k	3.9k	2.9k	160	29.4k
William C. Hahn United States	101	26.5k 1.3×	11.2k 1.2×	7.8k 1.2×	5.8k 1.5×	3.5k 1.2×	293	40.9k
Lena Claesson‐Welsh Sweden	87	22.2k 1.1×	6.9k 0.7×	5.8k 0.9×	1.7k 0.4×	4.8k 1.7×	256	32.3k
Alan D. D’Andrea United States	98	25.3k 1.2×	11.2k 1.2×	6.7k 1.0×	1.7k 0.5×	2.9k 1.0×	313	32.7k
Mary W. Brooks United States	24	13.1k 0.6×	10.7k 1.2×	4.7k 0.7×	2.3k 0.6×	2.0k 0.7×	28	21.2k
Martine F. Roussel United States	83	19.4k 1.0×	12.4k 1.3×	3.3k 0.5×	1.4k 0.4×	2.9k 1.0×	242	27.9k
Julian Downward United Kingdom	101	30.1k 1.5×	11.4k 1.2×	4.9k 0.7×	1.6k 0.4×	5.9k 2.1×	292	41.7k
Thomas Ried United States	84	17.7k 0.9×	7.3k 0.8×	6.2k 0.9×	1.3k 0.3×	2.3k 0.8×	378	27.8k
Ruggero De Maria Italy	72	13.1k 0.6×	9.1k 1.0×	6.1k 0.9×	1.1k 0.3×	2.2k 0.8×	257	22.8k
Robert T. Abraham United States	88	20.2k 1.0×	7.5k 0.8×	4.4k 0.7×	1.5k 0.4×	3.2k 1.1×	215	29.0k
Erik Larsson Sweden	56	21.9k 1.1×	8.3k 0.9×	9.7k 1.4×	1.3k 0.3×	2.5k 0.9×	208	34.1k

Countries citing papers authored by Lynda Chin

Since Specialization

Citations

This map shows the geographic impact of Lynda Chin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lynda Chin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lynda Chin more than expected).

Fields of papers citing papers by Lynda Chin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lynda Chin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lynda Chin. The network helps show where Lynda Chin may publish in the future.

Co-authorship network of co-authors of Lynda Chin

This figure shows the co-authorship network connecting the top 25 collaborators of Lynda Chin. A scholar is included among the top collaborators of Lynda Chin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lynda Chin. Lynda Chin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Watson, Ian R., Li Li, Tony Gutschner, et al.. (2014). The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF. Cancer Research. 74(17). 4845–4852. 116 indexed citations

Kwong, Lawrence N. & Lynda Chin. (2014). Chromosome 10, Frequently Lost in Human Melanoma, Encodes Multiple Tumor-Suppressive Functions. Cancer Research. 74(6). 1814–1821. 16 indexed citations

Chew, Su Kit, Dong Lu, Lia S. Campos, et al.. (2014). Polygenic in vivovalidation of cancer mutations using transposons. Genome biology. 15(9). 455–455. 3 indexed citations

Yang, Lixing, Lovelace J. Luquette, Nils Gehlenborg, et al.. (2014). Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes. Cell. 157(7). 1736–1736. 7 indexed citations

Sanborn, Zack, Sofie R. Salama, Mia Grifford, et al.. (2013). Double Minute Chromosomes in Glioblastoma Multiforme Are Revealed by Precise Reconstruction of Oncogenic Amplicons. Cancer Research. 73(19). 6036–6045. 73 indexed citations

Gutiérrez, Alejandro, Suzanne E. Dahlberg, Donna Neuberg, et al.. (2010). Absence of Biallelic TCR γ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia. Journal of Clinical Oncology. 28(24). 3816–3823. 69 indexed citations

Jeon, Hye-Min, Xun Jin, Se-Yeong Oh, et al.. (2008). Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes & Development. 22(15). 2028–2033. 101 indexed citations

Stommel, Jayne M., Alec C. Kimmelman, Haoqiang Ying, et al.. (2007). Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies. Science. 318(5848). 287–290. 699 indexed citations breakdown →

Oh, Se-Yeong, Xun Jin, Yun‐Jaie Choi, et al.. (2007). Direct Transcriptional Activation of Promyelocytic Leukemia Protein by IFN Regulatory Factor 3 Induces the p53-Dependent Growth Inhibition of Cancer Cells. Cancer Research. 67(23). 11133–11140. 38 indexed citations

10.

Martin, Eric S., Giovanni Tonon, Raktim Sinha, et al.. (2007). Common and Distinct Genomic Events in Sporadic Colorectal Cancer and Diverse Cancer Types. Cancer Research. 67(22). 10736–10743. 54 indexed citations

11.

Greshock, Joel, Bin Feng, Cristina Nogueira, et al.. (2007). A Comparison of DNA Copy Number Profiling Platforms. Cancer Research. 67(21). 10173–10180. 54 indexed citations

12.

Ji, Hongbin, Zhenxiong Wang, Samanthi A. Perera, et al.. (2007). Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models. Cancer Research. 67(10). 4933–4939. 137 indexed citations

13.

Rivera, Miguel N., Woo‐Jae Kim, Julie Wells, et al.. (2007). An X Chromosome Gene, WTX , Is Commonly Inactivated in Wilms Tumor. Science. 315(5812). 642–645. 225 indexed citations

14.

Liu, Fenghua, Peter J. Park, Weil Lai, et al.. (2006). A Genome-Wide Screen Reveals Functional Gene Clusters in the Cancer Genome and Identifies EphA2 as a Mitogen in Glioblastoma. Cancer Research. 66(22). 10815–10823. 94 indexed citations

15.

Maher, Elizabeth A., Cameron Brennan, Patrick Y. Wen, et al.. (2006). Marked Genomic Differences Characterize Primary and Secondary Glioblastoma Subtypes and Identify Two Distinct Molecular and Clinical Secondary Glioblastoma Entities. Cancer Research. 66(23). 11502–11513. 140 indexed citations

16.

Smolen, Gromoslaw A., Beth Muir, Gayatry Mohapatra, et al.. (2006). Frequent Met Oncogene Amplification in a Brca1/Trp53 Mouse Model of Mammary Tumorigenesis. Cancer Research. 66(7). 3452–3455. 32 indexed citations

17.

Brennan, Cameron, Yunyu Zhang, Christopher Leo, et al.. (2004). High-Resolution Global Profiling of Genomic Alterations with Long Oligonucleotide Microarray. Cancer Research. 64(14). 4744–4748. 101 indexed citations

18.

Yang, Fan, Glenn Merlino, & Lynda Chin. (2001). Genetic dissection of melanoma pathways in the mouse. Seminars in Cancer Biology. 11(3). 261–268. 17 indexed citations

19.

Muhle, Rebecca, et al.. (1997). Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature. 387(6628). 49–55. 728 indexed citations breakdown →

20.

Rao, Govinda, Leila Alland, Peter Guida, et al.. (1996). Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.. PubMed. 12(5). 1165–72. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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