Junichi Sadoshima

63.7k total citations · 17 hit papers
372 papers, 36.7k citations indexed

About

Junichi Sadoshima is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Epidemiology. According to data from OpenAlex, Junichi Sadoshima has authored 372 papers receiving a total of 36.7k indexed citations (citations by other indexed papers that have themselves been cited), including 227 papers in Molecular Biology, 110 papers in Cardiology and Cardiovascular Medicine and 97 papers in Epidemiology. Recurrent topics in Junichi Sadoshima's work include Autophagy in Disease and Therapy (92 papers), Mitochondrial Function and Pathology (40 papers) and Cardiac Ischemia and Reperfusion (39 papers). Junichi Sadoshima is often cited by papers focused on Autophagy in Disease and Therapy (92 papers), Mitochondrial Function and Pathology (40 papers) and Cardiac Ischemia and Reperfusion (39 papers). Junichi Sadoshima collaborates with scholars based in United States, Japan and Italy. Junichi Sadoshima's co-authors include Seigo Izumo, Peiyong Zhai, Sebastiano Sciarretta, Michinari Nakamura, Stephen F. Vatner, Daniela Zablocki, Yasuhiro Maejima, Tetsuro Ago, Shouji Matsushima and Shinichi Oka and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Junichi Sadoshima

364 papers receiving 36.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion

2007 1.3k citations Yutaka Matsui, Hiromitsu Takagi et al. Circulation Research profile →
Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 1.2k citations Junichi Sadoshima, Seigo Izumo Circulation Research profile →
Mechanisms of physiological and pathological cardiac hypertrophy

2018 1.1k citations Junichi Sadoshima et al. profile →
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

1993 1.1k citations Junichi Sadoshima et al. profile →
Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart

2007 939 citations Shumin Gao, Peiyong Zhai et al. Circulation Research profile →
THE CELLULAR AND MOLECULAR RESPONSE OF CARDIAC MYOCYTES TO MECHANICAL STRESS

1997 677 citations Junichi Sadoshima, Seigo Izumo profile →
NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

2010 613 citations Peiyong Zhai, Junichi Sadoshima et al. profile →
Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

2010 570 citations Nirmala Hariharan, Yasuhiro Maejima et al. Circulation Research profile →
Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism.

1993 547 citations Junichi Sadoshima, Seigo Izumo profile →
Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

2006 522 citations Junichi Sadoshima et al. Journal of Biological Chemistry profile →
Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress

2014 480 citations Yoshiyuki Ikeda, Yasuhiro Maejima et al. Circulation Research profile →
The Role of Autophagy in the Heart

2017 432 citations Sebastiano Sciarretta, Yasuhiro Maejima et al. profile →
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

2013 428 citations Yasuhiro Maejima, Peiyong Zhai et al. profile →
Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure

2016 370 citations Peiyong Zhai, Yoshiyuki Ikeda et al. Circulation profile →
Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

2019 364 citations Mingming Tong, Toshiro Saito et al. Circulation Research profile →
New Insights Into the Role of mTOR Signaling in the Cardiovascular System

2018 345 citations Sebastiano Sciarretta, Giacomo Frati et al. Circulation Research profile →
Aging and Autophagy in the Heart

2016 344 citations Yoshiyuki Ikeda, Sebastiano Sciarretta et al. Circulation Research profile →

Peers

Countries citing papers authored by Junichi Sadoshima

Since Specialization

Citations

This map shows the geographic impact of Junichi Sadoshima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Junichi Sadoshima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Junichi Sadoshima more than expected).

Fields of papers citing papers by Junichi Sadoshima

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Junichi Sadoshima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Junichi Sadoshima. The network helps show where Junichi Sadoshima may publish in the future.

Co-authorship network of co-authors of Junichi Sadoshima

This figure shows the co-authorship network connecting the top 25 collaborators of Junichi Sadoshima. A scholar is included among the top collaborators of Junichi Sadoshima based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Junichi Sadoshima. Junichi Sadoshima is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Decoding the Impact of the Hippo Pathway on Different Cell Types in Heart Failure 2024 ·Circulation Journal ·(unknown), Jamie Francisco, Dominic P. Del Re, Junichi Sadoshima	2
2	A transcriptional regulatory mechanism of genes in the tricarboxylic acid cycle in the heart 2024 ·Journal of Biological Chemistry ·(unknown), (unknown), (unknown), (unknown), Tong Liu, Hong Li, (unknown), Junco S. Warren, (unknown), (unknown), Junichi Sadoshima, (unknown)	4
3	Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity 2023 ·Journal of Clinical Investigation ·(unknown), Supreet Kaur, Chrysovalantou E. Xirouchaki, Pei Kee Goh, Florian Wiede, Amanda J. Genders, Melanie Tran, Yaoyao Jia, (unknown), Wendy A. Brown, Catriona McLean, Junichi Sadoshima, Matthew J. Watt, Tony Tiganis	25
4	Metabolic control of mitophagy 2023 ·European Journal of Clinical Investigation ·Andreas Zimmermann, Frank Madeo, Abhinav Diwan, Junichi Sadoshima, Simon Sedej, Guido Kroemer, Mahmoud Abdellatif	19
5	NAD ⁺ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy 2021 ·Circulation Heart Failure ·Ying Ann Chiao, (unknown), (unknown), Rong Tian, Junichi Sadoshima, Xiaojian Shi, Haiwei Gu, Chi Fung Lee	43
6	Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance 2021 ·Science Advances ·Chrysovalantou E. Xirouchaki, Yaoyao Jia, Meagan J. McGrath, (unknown), Melanie Tran, Troy L. Merry, (unknown), Matthew J. Eramo, (unknown), Jonathan S. T. Woodhead, Randall F. D’Souza, (unknown), Ekaterina Salimova, Cheng Huang, Ralf B. Schittenhelm, Junichi Sadoshima, Matthew J. Watt, Christina A. Mitchell, Tony Tiganis	66
7	KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy 2020 ·Circulation Research ·Ioannis D. Kyriazis, Matthew Hoffman, (unknown), Anna Maria Lucchese, (unknown), (unknown), Chao Wang, Thomas D. Bannister, Melpo Christofidou‐Solomidou, Shinichi Oka, Junichi Sadoshima, Walter J. Koch, Ira J. Goldberg, Vincent W. Yang, Agnieszka B. Bialkowska, Georgios Kararigas, Konstantinos Drosatos	107
8	Dual PPARα/γ activation inhibitsSIRT1-PGC1α axis and causes cardiac dysfunction 2019 ·JCI Insight ·(unknown), Ioannis D. Kyriazis, Shinichi Oka, (unknown), Yujia Yue, Estela Área-Gómez, Christine J. Pol, Ying Tian, Wataru Mizushima, (unknown), Diego Scerbo, P. Christian Schulze, Mete Civelek, Junichi Sadoshima, Muniswamy Madesh, Ira J. Goldberg, Konstantinos Drosatos	64
9	Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart 2019 ·Cardiovascular Research ·Shinichi Oka, (unknown), (unknown), Shohei Ikeda, Wataru Mizushima, (unknown), Peiyong Zhai, Mingming Tong, Jaemin Byun, (unknown), (unknown), Chun-Yang Huang, Toshihide Kashihara, Mengyuan Zhao, Jihoon Nah, Bin Tian, Yoko Hirabayashi, Junji Yodoi, Junichi Sadoshima	26
10	Sex differences in response to miRNA‐34a therapy in mouse models of cardiac disease: identification of sex‐, disease‐ and treatment‐regulated miRNAs 2016 ·The Journal of Physiology ·Bianca C. Bernardo, Jenny Y. Y. Ooi, Aya Matsumoto, Yow Keat Tham, Saloni Singla, Helen Kiriazis, Natalie L. Patterson, Junichi Sadoshima, Susanna Obad, Ruby C.Y. Lin, Julie R. McMullen	38
11	Abstract 19501: Ulk1 Induces Mitochondrial Autophagy by Regulating Mitochondrial Fission and Alternative Autophagy in the Heart 2016 ·Circulation ·Toshiro Saito, Junichi Sadoshima	2
12	New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart 2014 ·Oxidative Medicine and Cellular Longevity ·Yoshiyuki Ikeda, Sebastiano Sciarretta, Narayani Nagarajan, Speranza Rubattu, Massimo Volpe, Giacomo Frati, Junichi Sadoshima	100
13	Abstract 18056: Activation of Nox4 Promotes Cardiomyocyte Autophagy and Survival During Nutrient Starvation 2012 ·Circulation ·Sebastiano Sciarretta, Peiyong Zhai, Massimo Volpe, Junichi Sadoshima	1
14	Abstract 18096: Trehalose, a Natural Dissacharide, Reduces Cardiac Remodeling After Myocardial Infarction Through Autophagy Activation 2012 ·Circulation ·Sebastiano Sciarretta, Peiyong Zhai, Massimo Volpe, Junichi Sadoshima	1
15	Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes breakdown → 2010 ·Circulation Research ·Nirmala Hariharan, Yasuhiro Maejima, Jun Nakae, Jihye Paik, Ronald A. DePinho, Junichi Sadoshima	570
16	Abstract 3290: Increased Type 5 Adenylyl Cyclase Expression Mediates Chronic Catecholamine Stress via Increases in Oxidative Stress and Down-regulation of MnSOD 2009 ·Circulation ·Lo Lai, (unknown), Chelin Hu, Shumin Gao, (unknown), Yoshihiro Ishikawa, Junichi Sadoshima, Stephen F. Vatner, Dorothy E. Vatner	1
17	Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation 2009 ·American Journal Of Pathology ·Lynette Pretorius, Xiao‐Jun Du, Elizabeth A. Woodcock, Helen Kiriazis, Ruby C.Y. Lin, Silvana Marasco, Robert L. Medcalf, Ziqiu Ming, Geoffrey A. Head, Joon Win Tan, Nelly Cemerlang, Junichi Sadoshima, Tetsuo Shioi, Seigo Izumo, Е. В. Лукошкова, Anthony M. Dart, Garry Jennings, Julie R. McMullen	152
18	Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion breakdown → 2007 ·Circulation Research ·Yutaka Matsui, Hiromitsu Takagi, Xueping Qu, Maha Abdellatif, Hideyuki Sakoda, Tomoichiro Asano, Beth Levine, Junichi Sadoshima	1284
19	An Angiotensin II Type 1 Receptor Mutant Lacking Epidermal Growth Factor Receptor Transactivation Does Not Induce Angiotensin II–Mediated Cardiac Hypertrophy 2006 ·Circulation Research ·Peiyong Zhai, Jonathan Galeotti, (unknown), Eric Holle, Xianzhong Yu, Thomas E. Wagner, Junichi Sadoshima	79
20	Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy 2003 ·Journal of Clinical Investigation ·Shimako Yamamoto, Guiping Yang, Daniela Zablocki, Jing Liu, Chull Hong, Song‐Jung Kim, (unknown), Mari Odashima, Jill Thaisz, Ghassan Yehia, Carlos A. Molina, Atsuko Yatani, Dorothy E. Vatner, Stephen F. Vatner, Junichi Sadoshima	247

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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