Roberto D. Polakiewicz

14.5k citations

69 papers · 9.1k indexed · 4 hit papers · h-index 41

Impact in

Molecular Biology top 0.5%
- PI3K/AKT/mTOR signaling in cancer
- Ubiquitin and proteasome pathways
- Metabolism, Diabetes, and Cancer
- Protein Kinase Regulation and GTPase Signaling
- Protein Degradation and Inhibitors
Cancer Research top 1%
- Cancer, Hypoxia, and Metabolism

Papers in

Hematology 15
- Chronic Myeloid Leukemia Treatments 8
- Multiple Myeloma Research and Treatments 6
Genetics 11

Co-authors: Michael J. Comb Nahum Sonenberg Anne‐Claude Gingras Steven P. Gygi Brian Raught Ruedi Aebersold A. John Rush Ailan Guo
Journals: Blood (9 papers)Journal of Biological Chemistry (7 papers)Molecular and Cellular Biology (5 papers)Proceedings of the National Academy of Sciences (5 papers)Journal of Clinical Investigation (3 papers)
Partner nations: United States Israel Canada

In The Last Decade

Roberto D. Polakiewicz

68 papers receiving 9.0k citations

Hit Papers

align trajectories log scale

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth 2009 · 618 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2009 Science Signaling
2004 Nature Biotechnology
2001 Genes & Development
1999 Genes & Development

Peers

Countries citing papers authored by Roberto D. Polakiewicz

Since Specialization

Citations

This map shows the geographic impact of Roberto D. Polakiewicz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberto D. Polakiewicz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberto D. Polakiewicz more than expected).

Fields of papers citing papers by Roberto D. Polakiewicz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberto D. Polakiewicz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberto D. Polakiewicz. The network helps show where Roberto D. Polakiewicz may publish in the future.

Co-authors

The 25 scholars most cited alongside Roberto D. Polakiewicz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Roberto D. Polakiewicz Line = papers co-authored together Roberto D. Polakiewicz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach Frontiers in Molecular Biosciences ·Justine Stehn, Scott Floyd, Erik Wilker, Hans Christian Reinhardt, Sylwia Sowa, Qiuying Huang, Roberto D. Polakiewicz, Nahum Sonenberg, Yi Wen Kong, Michael B. Yaffe	2023	0
2	Astrogliosis Induced by Brain Injury Is Regulated by Sema4B Phosphorylation eNeuro ·Andreia Regina Trindade de Mendonça, Sahar Sweetat, 赵灵智 ZHAO Ling-zhi, Yakov Fellig, Thorsten Wiederhold, Roberto D. Polakiewicz, Oded Behar	2015	23
3	Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14 Oncogene ·Peng Zhang, Ailan Guo, Anthony Possemato, Chao Wang, Lydia Beard, Cathleen R. Carlin, Sanford D. Markowitz, Roberto D. Polakiewicz, Zhiguo Wang	2012	32
4	A proteomics approach for the identification and cloning of monoclonal antibodies from serum Nature Biotechnology ·Wan Cheung Cheung, Sean A. Beausoleil, Xiaowu Zhang, Shuji Sato, M Fagerås, James S. Wieler, María José Sánchez Robert, Dainn Wie, Lana Popova, Michael J. Comb, A. John Rush, Roberto D. Polakiewicz	2012	130
5	Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD ⁺ Redox Homeostasis in Cancer Cells Molecular and Cellular Biology ·Jun Fan, Taro Hitosugi, Tae‐Wook Chung, Jianxin Xie, Qingyuan Ge, Ting‐Lei Gu, Roberto D. Polakiewicz, Georgia Z. Chen, Titus J. Boggon, Sagar Lonial, Fadlo R. Khuri, Sumin Kang, Jing Chen	2011	188
6	Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs RNA ·Liwei Rong, Mark Livingstone, Rami Sukarieh, Emmanuel Petroulakis, Anne‐Claude Gingras, Katherine Crosby, Bradley Smith, Roberto D. Polakiewicz, Jerry Pelletier, Maria Ferraiuolo, Nahum Sonenberg	2008	98
7	Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T Proceedings of the National Academy of Sciences ·Xiaodong Zhang, Ailan Guo, Jianshi Yu, Anthony Possemato, Yueting Chen, Weiping Zheng, Roberto D. Polakiewicz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Zhenghe Wang	2007	173
8	PBK/TOPK, a Proliferating Neural Progenitor-Specific Mitogen-Activated Protein Kinase Kinase Journal of Neuroscience ·Joseph D. Dougherty, Ainhoa García, Ichiro Nakano, Mark Livingstone, Umut Ozbagriacik, Roberto D. Polakiewicz, Eric Wexler, Michael V. Sofroniew, Harley I. Kornblum, Daniel H. Geschwind	2005	84
9	Insertion of c- Myc into Igh Induces B-Cell and Plasma-Cell Neoplasms in Mice Cancer Research ·Sung Sup Park, Joong Su Kim, Lino Tessarollo, James D. Owens, Liangping Peng, Seong‐Su Han, Fabian Szakács, Ted A. Torrey, Wan Cheung Cheung, Roberto D. Polakiewicz, Nicole E. McNeil, Thomas Ried, J. Frederic Mushinski, Herbert C. Morse, Siegfried Janz	2005	83
10	Novel targeted deregulation of c-Myc cooperates with Bcl-XL to cause plasma cell neoplasms in mice Journal of Clinical Investigation ·Wan Cheung Cheung, Joong Su Kim, Michael A. Linden, Liangping Peng, Brian G. Van Ness, Roberto D. Polakiewicz, Siegfried Janz	2004	79
11	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells Nature Biotechnology ·A. John Rush, Albrecht Moritz, Kimberly A. Lee, Ailan Guo, Valerie L. Goss, Erik J. Spek, Hui Zhang, Xiang‐ming Zha, Roberto D. Polakiewicz, Michael J. Comb Hit paper breakdown →	2004	913
12	Lysophosphatidic acid‐regulated mitogenic ERK signaling in androgen‐insensitive prostate cancer PC‐3 cells International Journal of Cancer ·榑林雄太, Jason S. Taub, Djouhri Nesrine, Roberto D. Polakiewicz, Axel Ullrich, Yehia Daaka	2002	77
13	Hierarchical phosphorylation of the translation inhibitor 4E-BP1 Genes & Development ·Anne‐Claude Gingras, Brian Raught, Steven P. Gygi, Anna Niedźwiecka, Mathieu Miron, S.K. Burley, Roberto D. Polakiewicz, Aleksandra Wysłouch‐Cieszyńska, Ruedi Aebersold, Nahum Sonenberg Hit paper breakdown →	2001	707
14	Phosphatidylinositol 3-Kinase-dependent Extracellular Calcium Influx Is Essential for CX3CR1-mediated Activation of the Mitogen-activated Protein Kinase Cascade Journal of Biological Chemistry ·Vikram Kansra, Christopher J. Groves, José Carlos Gutierrez‐Ramos, Roberto D. Polakiewicz	2001	49
15	Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism Genes & Development ·Anne‐Claude Gingras, Steven P. Gygi, Brian Raught, Roberto D. Polakiewicz, Robert T. Abraham, Merl F. Hoekstra, Ruedi Aebersold, Nahum Sonenberg Hit paper breakdown →	1999	1063
16	A Mitogen-activated Protein Kinase Pathway Is Required for μ-Opioid Receptor Desensitization Journal of Biological Chemistry ·Roberto D. Polakiewicz, P Manque, Lydia F. Dorner, Vikram Kansra, Michael J. Comb	1998	120
17	Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3–q13.5 Genomics ·Roberto D. Polakiewicz, David J. Munroe, 论剑, Kazimierz T. Tycowski, Norma J. Nowak, Thomas B. Shows, David E. Housman, David C. Page	1995	13
18	Lipopolysaccharide induces proenkephalin gene expression in rat lymph nodes and adrenal glands. Endocrinology ·Oded Behar, Haim Ovadia, Roberto D. Polakiewicz, Hadar Rosen	1994	22
19	Regulation of Proenkephalin A Messenger Ribonucleic Acid Levels in Normal B Lymphocytes: Specific Inhibition by Glucocorticoid Hormones and Superinduction by Cycloheximide* Endocrinology ·Oded Behar, Haim Ovadia, Roberto D. Polakiewicz, Oded Abramsky, Haim Rosen	1991	24
20	Expression of proenkephalin A mRNA and enkephalin-containing peptides in cultured fibroblasts Biochemical and Biophysical Research Communications ·Hadar Rosen, Roberto D. Polakiewicz, Rabi Simantov	1990	8

About Roberto D. Polakiewicz

Roberto D. Polakiewicz is a scholar working on Hematology, Genetics, Cellular and Molecular Neuroscience, Molecular Biology and Developmental Neuroscience, having authored 69 papers that have together received 9.1k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (15 papers), PI3K/AKT/mTOR signaling in cancer (11 papers), Protein Kinase Regulation and GTPase Signaling (9 papers), Monoclonal and Polyclonal Antibodies Research (9 papers), Receptor Mechanisms and Signaling (9 papers), Chronic Myeloid Leukemia Treatments (8 papers), Glycosylation and Glycoproteins Research (6 papers) and Multiple Myeloma Research and Treatments (6 papers). The work is most often cited by research in Molecular Biology (6.7k citations), Cancer Research (1.3k citations), Hematology (764 citations), Genetics (606 citations) and Oncology (1.4k citations). Roberto D. Polakiewicz has collaborated with scholars based in United States, Israel and Canada. Frequent co-authors include Michael J. Comb, Nahum Sonenberg, Anne‐Claude Gingras, Steven P. Gygi, Brian Raught, Ruedi Aebersold, A. John Rush, Ailan Guo, Kimberly A. Lee and Robert T. Abraham. Their work appears in journals such as Blood, Journal of Biological Chemistry, Molecular and Cellular Biology, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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