Ailan Guo

13.9k citations

49 papers · 8.0k indexed · 4 hit papers · h-index 37

Impact in

Molecular Biology top 1%
- Ubiquitin and proteasome pathways
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- RNA modifications and cancer
Oncology top 1%
- Drug Transport and Resistance Mechanisms

Papers in

Molecular Biology 37
- Epigenetics and DNA Methylation 7
- PI3K/AKT/mTOR signaling in cancer 6
- Cancer-related gene regulation 6
- Ubiquitin and proteasome pathways 5
- RNA modifications and cancer 5
Oncology 13
- Drug Transport and Resistance Mechanisms 6

Co-authors: A. John Rush Michael J. Comb Anthony Possemato Roberto D. Polakiewicz Steven P. Gygi Kimberly A. Lee Daniel F. Klessig Albrecht Moritz
Journals: Proceedings of the National Academy of Sciences (3 papers)PLANT PHYSIOLOGY (2 papers)Molecular & Cellular Proteomics (2 papers)Nature Communications (2 papers)Cell (2 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Ailan Guo

49 papers receiving 7.9k citations

Hit Papers

align trajectories log scale

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation 2013 · 478 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Nature Methods
2011 Molecular Cell
2004 Nature Biotechnology
1994 The Plant Cell

Peers

Countries citing papers authored by Ailan Guo

Since Specialization

Citations

This map shows the geographic impact of Ailan Guo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ailan Guo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ailan Guo more than expected).

Fields of papers citing papers by Ailan Guo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ailan Guo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ailan Guo. The network helps show where Ailan Guo may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ailan Guo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ailan Guo Line = papers co-authored together Ailan Guo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Multiplexed Phosphoproteomic Profiling Using Titanium Dioxide and Immunoaffinity Enrichments Reveals Complementary Phosphorylation Events Journal of Proteome Research ·Anthony Possemato, João A. Paulo, Justo Bautista Morán Zavala, Ailan Guo, Steven P. Gygi, Sean A. Beausoleil	2017	45
2	Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer Molecular Cell ·Ioannis Sanidas, Christos Polytarchou, Maria Hatziapostolou, Scott A. Ezell, Filippos Kottakis, Lan Hu, Ailan Guo, Jianxin Xie, Michael J. Comb, Dimitrios Iliopoulos, Philip N. Tsichlis	2014	94
3	CARM1 Methylates Chromatin Remodeling Factor BAF155 to Enhance Tumor Progression and Metastasis Cancer Cell ·Lu Wang, Zibo Zhao, Mark B. Meyer, Sandeep Saha, Menggang Yu, Ailan Guo, Kari B. Wisinski, Wei Huang, Weibo Cai, J. Wesley Pike, Ming Yuan, Paul Ahlquist, Wei Xu	2014	204
4	Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation Molecular & Cellular Proteomics ·Ailan Guo, Hongbo Gu, Jing Zhou, Justo Bautista Morán Zavala, Yi Wang, Kimberly A. Lee, Vicky K. Yang, Mike Aguiar, Jon M. Kornhauser, Xiaoying Jia, Jianmin Ren, Sean A. Beausoleil, Jeffrey C. Silva, Vidyasiri Vemulapalli, Mark T. Bedford, Michael J. Comb	2013	371
5	Global Identification of Modular Cullin-RING Ligase Substrates Cell ·Michael J. Emanuele, Andrew E. H. Elia, Qikai Xu, Claudio R. Thoma, Lior Izhar, Yumei Leng, Ailan Guo, Yi‐Ning Chen, A. John Rush, Paul Wei‐Che Hsu, Hsueh-Chi S. Yen, Stephen J. Elledge	2012	4
6	Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14 Oncogene ·Peng Zhang, Ailan Guo, Anthony Possemato, Chao Wang, Lydia Beard, Cathleen R. Carlin, Sanford D. Markowitz, Roberto D. Polakiewicz, Zhiguo Wang	2012	32
7	Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome Molecular Cell ·Woong Kim, Eric J. Bennett, Edward L. Huttlin, Ailan Guo, Jing Li, Anthony Possemato, Mathew E. Sowa, Ramin Rad, A. John Rush, Michael J. Comb, J. Wade Harper, Steven P. Gygi Hit paper breakdown →	2011	1287
8	Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T Proceedings of the National Academy of Sciences ·Xiaodong Zhang, Ailan Guo, Jianshi Yu, Anthony Possemato, Yueting Chen, Weiping Zheng, Roberto D. Polakiewicz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Zhenghe Wang	2007	173
9	Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2) BMC Medicine ·Anita Lalloo, Feng Luo, Ailan Guo, P. Szlavik, Lu Cui, Viral Vyas, Eric H. Rubin, Patrick J. Sinko	2004	54
10	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells Nature Biotechnology ·A. John Rush, Albrecht Moritz, Kimberly A. Lee, Ailan Guo, Valerie L. Goss, Erik J. Spek, Hui Zhang, Xiang‐ming Zha, Roberto D. Polakiewicz, Michael J. Comb Hit paper breakdown →	2004	913
11	Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1 Drug Metabolism and Disposition ·Feng Luo, P. Szlavik, Ailan Guo, Eric H. Rubin, Patrick J. Sinko	2002	86
12	Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT) Drug Metabolism and Disposition ·Ailan Guo, Rima Amno, Peidi Hu, Patrick J. Sinko	2002	72
13	Activation of a diverse set of genes during the tobacco resistance response to TMV is independent of salicylic acid; induction of a subset is also ethylene independent The Plant Journal ·Ailan Guo, 義雄若松, Daniel F. Klessig	2000	51
14	Fission yeast contains an rDNA binding activity that interacts specifically with regulatory sequences for ribosomal RNA synthesis Gene ·Ailan Guo, Ling Chen, Annie Zhao, Yangang Wang, Louise Pape	2000	2
15	Characterization of a tobacco epoxide hydrolase gene induced during the resistance response to TMV The Plant Journal ·Ailan Guo, Jörg Durner, Daniel F. Klessig	1998	46
16	Characterization of the Regional Intestinal Kinetics of Drug Efflux in Rat and Human Intestine and in Caco-2 Cells Pharmaceutical Research ·A.W.L. van der Werf, Ailan Guo, Daniel A. Norris, Peidi Hu, Vasconcelos Buur, Patrick J. Sinko	1998	185
17	Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir Biochemical and Biophysical Research Communications ·Praveen Balimane, Ikumi Tamai, Ailan Guo, Takeo Nakanishi, Nour Eldeen, Frederick H. Leibach, Akira Tsuji, Patrick J. Sinko	1998	170
18	An Immunoaffinity Purified Schizosaccharomyces Pombe TBP-containing Complex Directs Correct Initiation of the S.pombe rRNA Gene Promoter Nucleic Acids Research ·Lei Chen, Ailan Guo, Lars Pape	1997	6
19	Molecular cloning and analysis of Schizosaccharomyces pombe Reb1p: sequence-specific recognition of two sites in the far upstream rDNA intergenic spacer Nucleic Acids Research ·Layla Abd Al-Jaleel Mohsin, Ailan Guo, Zhihong Liu, Lars Pape	1997	33
20	Rice Cationic Peroxidase Accumulates in Xylem Vessels during Incompatible Interactions with Xanthomonas oryzae pv oryzae PLANT PHYSIOLOGY ·Simon A. Young, Ailan Guo, James A. Guikema, Frank F. White, Jan E. Leach	1995	126

About Ailan Guo

Ailan Guo is a scholar working on Molecular Biology, Oncology, Genetics, Spectroscopy and Pediatrics, Perinatology and Child Health, having authored 49 papers that have together received 8.0k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (7 papers), Plant-Microbe Interactions and Immunity (6 papers), PI3K/AKT/mTOR signaling in cancer (6 papers), Cancer-related gene regulation (6 papers), Drug Transport and Resistance Mechanisms (6 papers), Ubiquitin and proteasome pathways (5 papers), RNA modifications and cancer (5 papers) and Advanced Proteomics Techniques and Applications (4 papers). The work is most often cited by research in Molecular Biology (5.9k citations), Oncology (1.7k citations), Spectroscopy (907 citations), Cell Biology (873 citations) and Cancer Research (494 citations). Ailan Guo has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include A. John Rush, Michael J. Comb, Anthony Possemato, Roberto D. Polakiewicz, Steven P. Gygi, Kimberly A. Lee, Daniel F. Klessig, Albrecht Moritz, Patrick J. Sinko and Eric J. Bennett. Their work appears in journals such as Proceedings of the National Academy of Sciences, PLANT PHYSIOLOGY, Molecular & Cellular Proteomics, Nature Communications and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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