Victor E. Velculescu

119.3k total citations · 25 hit papers
184 papers, 54.3k citations indexed

About

Victor E. Velculescu is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Victor E. Velculescu has authored 184 papers receiving a total of 54.3k indexed citations (citations by other indexed papers that have themselves been cited), including 112 papers in Molecular Biology, 88 papers in Cancer Research and 69 papers in Oncology. Recurrent topics in Victor E. Velculescu's work include Cancer Genomics and Diagnostics (81 papers), Genetic factors in colorectal cancer (29 papers) and Epigenetics and DNA Methylation (24 papers). Victor E. Velculescu is often cited by papers focused on Cancer Genomics and Diagnostics (81 papers), Genetic factors in colorectal cancer (29 papers) and Epigenetics and DNA Methylation (24 papers). Victor E. Velculescu collaborates with scholars based in United States, Netherlands and Denmark. Victor E. Velculescu's co-authors include Kenneth W. Kinzler, Bert Vogelstein, Luis A. Díaz, Nickolas Papadopoulos, Wafik S. El‐Deiry, Shibin Zhou, Lin Zhang, Bert Vogelstein, David Pei‐Cheng Lin and Daniel B. Levy and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Victor E. Velculescu

181 papers receiving 53.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

WAF1, a potential mediator of p53 tumor suppression

1993 7.2k citations Victor E. Velculescu et al. profile →
Cancer Genome Landscapes

2013 5.3k citations Bert Vogelstein, Nickolas Papadopoulos et al. Science profile →
IDH1andIDH2Mutations in Gliomas

2009 4.2k citations Hai Yan, D. Williams Parsons et al. profile →
Serial Analysis of Gene Expression

1995 2.7k citations Victor E. Velculescu, Bert Vogelstein et al. Science profile →
High Frequency of Mutations of the PIK3CA Gene in Human Cancers

2004 2.7k citations Yardena Samuels, Zhenghe Wang et al. Science profile →
Distant metastasis occurs late during the genetic evolution of pancreatic cancer

2010 1.8k citations Shinichi Yachida, Siân Jones et al. profile →
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 1.8k citations Victor E. Velculescu et al. profile →
Genes Expressed in Human Tumor Endothelium

2000 1.5k citations Carlo Rago, Victor E. Velculescu et al. Science profile →
DAXX / ATRX , MEN1 , and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

2011 1.2k citations Yuchen Jiao, Chanjuan Shi et al. Science profile →
Gene Expression Profiles in Normal and Cancer Cells

1997 1.0k citations Victor E. Velculescu, Ralph H. Hruban et al. Science profile →
RAF/RAS oncogenes and mismatch-repair status

2002 990 citations Harith Rajagopalan, Alberto Bardelli et al. profile →
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

2010 923 citations Siân Jones, Tian‐Li Wang et al. Science profile →
The colorectal microRNAome

2006 757 citations Jordan M. Cummins, Yiping He et al. Proceedings of the National Academy of Sciences profile →
Characterization of the Yeast Transcriptome

1997 752 citations Victor E. Velculescu, Bert Vogelstein et al. profile →
Mutant PIK3CA promotes cell growth and invasion of human cancer cells

2005 727 citations Yardena Samuels, Luis A. Díaz et al. profile →
Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

2009 724 citations Jihye Yun, Carlo Rago et al. Science profile →
Comparative lesion sequencing provides insights into tumor evolution

2008 596 citations Siân Jones, Wei-Dong Chen et al. Proceedings of the National Academy of Sciences profile →
Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

2009 565 citations Siân Jones, Ralph H. Hruban et al. Science profile →
Allelic Variation in Human Gene Expression

2002 546 citations Victor E. Velculescu, Bert Vogelstein et al. Science profile →
A Phosphatase Associated with Metastasis of Colorectal Cancer

2001 537 citations Alberto Bardelli, Victor E. Velculescu et al. Science profile →
Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

2014 533 citations Victor E. Velculescu et al. profile →
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

1995 525 citations Victor E. Velculescu et al. profile →
The PIK3CA gene is mutated with high frequency in human breast cancers

2004 519 citations Yardena Samuels, Natalie Silliman et al. profile →
Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

2012 474 citations Rebecca Leary, Mark Sausen et al. Science Translational Medicine profile →
Epitope Landscape in Breast and Colorectal Cancer

2008 318 citations D. Williams Parsons, Victor E. Velculescu et al. Cancer Research profile →

Peers

Countries citing papers authored by Victor E. Velculescu

Since Specialization

Citations

This map shows the geographic impact of Victor E. Velculescu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Victor E. Velculescu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Victor E. Velculescu more than expected).

Fields of papers citing papers by Victor E. Velculescu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Victor E. Velculescu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Victor E. Velculescu. The network helps show where Victor E. Velculescu may publish in the future.

Co-authorship network of co-authors of Victor E. Velculescu

This figure shows the co-authorship network connecting the top 25 collaborators of Victor E. Velculescu. A scholar is included among the top collaborators of Victor E. Velculescu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Victor E. Velculescu. Victor E. Velculescu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity 2018 ·Cancer Immunology Research ·Ludmila Danilova, Valsamo Anagnostou, Justina X. Caushi, John-William Sidhom, Haidan Guo, Hok Yee Chan, Prerna Suri, Ada Tam, Jiajia Zhang, Margueritta El Asmar, Kristen A. Marrone, Jarushka Naidoo, Julie R. Brahmer, Patrick M. Forde, Alexander S. Baras, Leslie Cope, Victor E. Velculescu, Drew M. Pardoll, Franck Housseau, Kellie N. Smith	99
2	Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors 2016 ·Molecular Cancer Therapeutics ·Christopher A. Hamm, Diarmuid Moran, (unknown), Patricia B. Trusk, Karen Pry, Mark Sausen, Siân Jones, Victor E. Velculescu, Massimo Cristofanilli, Sarah Bacus	44
3	The Effect of Preservative and Temperature on the Analysis of Circulating Tumor DNA 2016 ·Clinical Cancer Research ·Sonya Parpart-Li, Bjarne R. Bartlett, Maria Popoli, Vilmos Adleff, Laura Tucker, Rebecca Steinberg, Andrew Georgiadis, (unknown), Julie R. Brahmer, (unknown), Ilene Browner, Daniel A. Laheru, Victor E. Velculescu, Mark Sausen, Luis A. Díaz	145
4	Notch1 Mutations Are Drivers of Oral Tumorigenesis 2014 ·Cancer Prevention Research ·Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal, Wayne M. Koch, (unknown), David R. Riley, Samuel V. Angiuoli, Victor E. Velculescu, (unknown), David Sidransky	72
5	Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment 2014 ·Clinical Cancer Research ·Elena Garralda, Keren Paz, Pedro P. López‐Casas, Siân Jones, Amanda Katz, Lisa Kann, Fernando López‐Ríos, Francesca Sarno, Fátima Al‐Shahrour, David Vásquez, Elizabeth Bruckheimer, Samuel V. Angiuoli, Antonio Calles, Luis A. Díaz, Victor E. Velculescu, Alfonso Valencia, David Sidransky, Manuel Hidalgo	107
6	Ganitumab (AMG 479) Inhibits IGF-II–Dependent Ovarian Cancer Growth and Potentiates Platinum-Based Chemotherapy 2014 ·Clinical Cancer Research ·Pedro J. Beltran, Frank J. Calzone, Petia Mitchell, (unknown), Elaina Cajulis, Gordon Moody, Brian Belmontes, Chi-Ming Li, Steven Vonderfecht, Victor E. Velculescu, Guorong Yang, Jingwei Qi, Dennis J. Slamon, Gottfried E. Konecny	41
7	The Predictive Capacity of Personal Genome Sequencing 2012 ·Science Translational Medicine ·Nicholas J. Roberts, Joshua T Vogelstein, Giovanni Parmigiani, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu	135
8	Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors 2012 ·Clinical Cancer Research ·Shinichi Yachida, Catherine M. White, Yoshiki Naito, Yi Zhong, Jacqueline A. Brosnan‐Cashman, Anne M. Macgregor‐Das, Richard A. Morgan, Tyler Saunders, Daniel A. Laheru, Joseph M. Herman, Ralph H. Hruban, Alison P. Klein, Siân Jones, Victor E. Velculescu, Christopher L. Wolfgang, Christine A. Iacobuzio–Donahue	199
9	Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes 2012 ·Molecular Cancer Research ·Melinda D. Willard, Mary E. Lajiness, Isabella H. Wulur, Bo Feng, Michelle L. Swearingen, Mark Uhlik, Kenneth W. Kinzler, Victor E. Velculescu, Tobias Sjöblom, Sanford D. Markowitz, Steven M. Powell, Bert Vogelstein, Thomas D. Barber	15
10	Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma 2011 ·Science ·Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Mark Sausen, Laura D. Wood, Ralph H. Hruban, Fausto J. Rodríguez, Daniel P. Cahill, Roger E. McLendon, Gregory J. Riggins, Victor E. Velculescu, Sueli Mieko Oba‐Shinjo, Suely Kazue Nagahashi Marie, Bert Vogelstein, Darell D. Bigner, Hai Yan, Nickolas Papadopoulos, Kenneth W. Kinzler	370
11	DAXX / ATRX , MEN1 , and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors breakdown → 2011 ·Science ·Yuchen Jiao, Chanjuan Shi, Barish H. Edil, Roeland F. de Wilde, David S. Klimstra, Anirban Maitra, Richard D. Schulick, Laura H. Tang, Christopher L. Wolfgang, Michael A. Choti, Victor E. Velculescu, Luis A. Díaz, Bert Vogelstein, Kenneth W. Kinzler, Ralph H. Hruban, Nickolas Papadopoulos	1244
12	Functional Synergies yet Distinct Modulators Affected by Genetic Alterations in Common Human Cancers 2011 ·Cancer Research ·Marina Bessarabova, (unknown), Weiwei Shi, (unknown), (unknown), Kornélia Polyák, Victor E. Velculescu, Tatiana Nikolskaya, Yuri Nikolsky	8
13	Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells breakdown → 2009 ·Science ·Jihye Yun, Carlo Rago, Ian Cheong, (unknown), Philipp Angenendt, Harith Rajagopalan, Kerstin Schmidt, James K. V. Willson, Sandy D. Markowitz, Shibin Zhou, Luis A. Díaz, Victor E. Velculescu, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos	724
14	Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations 2009 ·Cancer Research ·Hannah Carter, Sining Chen, Leyla Işık, Svitlana Tyekucheva, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Rachel Karchin	321
15	Comparative lesion sequencing provides insights into tumor evolution breakdown → 2008 ·Proceedings of the National Academy of Sciences ·Siân Jones, Wei-Dong Chen, Giovanni Parmigiani, Frank Diehl, Niko Beerenwinkel, Tibor Antal, Arne Traulsen, Martin A. Nowak, Christopher Siegel, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Joseph Willis, Sanford D. Markowitz	596
16	Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T 2007 ·Proceedings of the National Academy of Sciences ·Xiaodong Zhang, Ailan Guo, Jianshi Yu, Anthony Possemato, Yueting Chen, Weiping Zheng, Roberto D. Polakiewicz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Zhenghe Wang	173
17	The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations 2007 ·Science ·Chuan‐Hsiang Huang, Diana Mandelker, Oleg Schmidt‐Kittler, Yardena Samuels, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Sandra B. Gabelli, L. Mario Amzel	446
18	The colorectal microRNAome breakdown → 2006 ·Proceedings of the National Academy of Sciences ·Jordan M. Cummins, Yiping He, Rebecca Leary, (unknown), Luis A. Díaz, Tobias Sjöblom, Omer Barad, Zvi Bentwich, Anna E. Szafranska, Emmanuel Labourier, Christopher K. Raymond, Brian S. Roberts, Hartmut Juhl, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu	757
19	High Frequency of Mutations of the PIK3CA Gene in Human Cancers breakdown → 2004 ·Science ·Yardena Samuels, Zhenghe Wang, Alberto Bardelli, Natalie Silliman, Janine Ptak, Steve Szabo, Hai Yan, Adi F. Gazdar, Steven M. Powell, Gregory J. Riggins, James K. V. Willson, Sanford D. Markowitz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu	2708
20	Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers 2004 ·Science ·Zhenghe Wang, Dong Shen, D. Williams Parsons, Alberto Bardelli, Jason A. Sager, Steve Szabo, Janine Ptak, Natalie Silliman, Brock A. Peters, Michiel S. van der Heijden, Giovanni Parmigiani, Hai Yan, Tian‐Li Wang, Greg Riggins, Steven M. Powell, James K. V. Willson, Sanford D. Markowitz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu	412

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