Richard B. Pearson

18.9k citations

134 papers · 13.2k · 6 hit papers · h-index 61

Impact in

Molecular Biology top 0.2%
- PI3K/AKT/mTOR signaling in cancer
- Protein Kinase Regulation and GTPase Signaling
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Ubiquitin and proteasome pathways
- Ion channel regulation and function
Cell Biology top 0.5%

Papers in

Molecular Biology 107
- Protein Kinase Regulation and GTPase Signaling 32
- PI3K/AKT/mTOR signaling in cancer 25
- RNA modifications and cancer 18
- Ubiquitin and proteasome pathways 16
- Chemical Synthesis and Analysis 10
- Genomics and Chromatin Dynamics 9
Oncology 29
- Cancer-related Molecular Pathways 9

Co-authors: Bruce E. Kemp (27 shared papers)Ross D. Hannan (51 shared papers)Katherine M. Hannan (37 shared papers)Patrick B. Dennis (5 shared papers)George Thomas (7 shared papers)Grant A. McArthur (23 shared papers)Wayne A. Phillips (6 shared papers)Stefano Fumagalli (1 shared paper)
Journals: Journal of Biological Chemistry (13 papers)Blood (6 papers)The EMBO Journal (5 papers)Proceedings of the National Academy of Sciences (5 papers)Cancer Research (5 papers)
Partner nations: Australia United States Switzerland

In The Last Decade

Richard B. Pearson

134 papers receiving 13.0k citations

Richard B. Pearson's Hit Papers

6 papers align trajectories log scale

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy 2021 · 234 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Signal Transduction and Targeted Therapy
2004 Cancer Research
1997 The EMBO Journal
1991 Methods in enzymology on CD-ROM/Methods in enzymology
1990 Trends in Biochemical Sciences
1986 Journal of Biological Chemistry

Peers

Countries citing papers authored by Richard B. Pearson

Since Specialization

Citations

This map shows the geographic impact of Richard B. Pearson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard B. Pearson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard B. Pearson more than expected).

Fields of papers citing papers by Richard B. Pearson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard B. Pearson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard B. Pearson. The network helps show where Richard B. Pearson may publish in the future.

Co-authors

The 25 scholars most cited alongside Richard B. Pearson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Richard B. Pearson Line = papers co-authored together Richard B. Pearson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 134 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations Methods in enzymology on CD-ROM/Methods in enzymology ·Richard B. Pearson, Bruce E. Kemp Hit paper breakdown →	1991	941
2	Protein kinase recognition sequence motifs Trends in Biochemical Sciences ·Bruce E. Kemp, Richard B. Pearson Hit paper breakdown →	1990	912
3	Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k The EMBO Journal ·Harold B.J. Jefferies, Stefano Fumagalli, Patrick B. Dennis, Christoph Reinhard, Richard B. Pearson, George Thomas Hit paper breakdown →	1997	786
4	Mutation of the *PIK3CA* Gene in Ovarian and Breast Cancer Cancer Research ·Ian Campbell, Sarah E. Russell, David Y.H. Choong, Karen G. Montgomery, Marianne L. Ciavarella, Christine S. F. Hooi, Briony E. Cristiano, Richard B. Pearson, Wayne A. Phillips Hit paper breakdown →	2004	743
5	A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. Journal of Biological Chemistry ·Heung‐Chin Cheng, Bruce E. Kemp, Richard B. Pearson, Alan Jay Smith, L Y Misconi, Scott M. Van Patten, Donal A. Walsh Hit paper breakdown →	1986	559
6	The Akt kinase signals directly to endothelial nitric oxide synthase Current Biology ·Belinda J. Michell, Julie Griffiths, Ken I. Mitchelhill, Ignacio Rodríguez‐Crespo, Tony Tiganis, Steven Bozinovski, P.R. Ortiz de Montellano, Bruce E. Kemp, Richard B. Pearson	1999	422
7	The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. The EMBO Journal ·Richard B. Pearson, Patrick B. Dennis, Jeongwoo Han, Nicholas A. Williamson, Sara C. Kozma, Richard E.H. Wettenhall, George Thomas	1995	383
8	mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF† Molecular and Cellular Biology ·Katherine M. Hannan, Yves Brandenburger, Anna Jenkins, Kerith Sharkey, Alice Cavanaugh, Lawrence Rothblum, Tom Moss, Gretchen Poortinga, Grant A. McArthur, Richard B. Pearson, Ross D. Hannan	2003	358
9	Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy Signal Transduction and Targeted Therapy ·Jian Kang, Natalie Brajanovski, Keefe T. Chan, Jiachen Xuan, Richard B. Pearson, Elaine Sanij Hit paper breakdown →	2021	234
10	Substrate specificity of a multifunctional calmodulin-dependent protein kinase. Journal of Biological Chemistry ·Richard B. Pearson, James R. Woodgett, Philip Cohen, Bruce E. Kemp	1985	223
11	AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy Oncogene ·Megan V. Astle, Katherine M. Hannan, Puiyee Ng, Rachel Lee, Amee J. George, Andy Hsu, Ygal Haupt, Ross D. Hannan, Richard B. Pearson	2011	220
12	The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence. Journal of Biological Chemistry ·Bruce E. Kemp, Richard B. Pearson, V. Guerriero, Indrani C. Bagchi, Anthony R. Means	1987	217
13	AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer Science Signaling ·Joanna C. Chan, Katherine M. Hannan, Kim Riddell, Pui Yee Ng, Abigail Peck, Rachel S. Lee, Sandy Hung, Megan V. Astle, Megan J. Bywater, Meaghan Wall, Gretchen Poortinga, Katarzyna Jastrzebski, Karen E. Sheppard, Brian A. Hemmings, Michael N. Hall, Ricky W. Johnstone, Grant A. McArthur, Ross D. Hannan, Richard B. Pearson	2011	198
14	Targeting PI3 Kinase/AKT/mTOR Signaling in Cancer Critical Reviews™ in Oncogenesis ·Karen E. Sheppard, Kathryn M. Kinross, Benjamin Solomon, Richard B. Pearson, Wayne A. Phillips	2012	193
15	Targeting the nucleolus for cancer intervention Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Jaclyn Quin, Jennifer R. Devlin, Donald P. Cameron, (unknown), Richard B. Pearson, Ross D. Hannan	2014	192
16	STIM1: a novel phosphoprotein located at the cell surface Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Shehnaaz S.M. Manji, Nigel J. Parker, R. T. Williams, Leonie van Stekelenburg, Richard B. Pearson, Marie Dziadek, Peter J. Smith	2000	188
17	Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function Growth Factors ·Katarzyna Jastrzebski, Katherine M. Hannan, Elissaveta B. Tchoubrieva, Ross D. Hannan, Richard B. Pearson	2007	187
18	Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis Cancer Cell ·Charbel Darido, Smitha R. Georgy, Tomasz Wilanowski, Sebastian Dworkin, Alana Auden, Quan Zhao, Gerhard Rank, Seema Srivastava, Moira Finlay, Anthony T. Papenfuss, Pier Paolo Pandolfi, Richard B. Pearson, Stephen M. Jane	2011	184
19	Regulatory and structural motifs of chicken gizzard myosin light chain kinase. Proceedings of the National Academy of Sciences ·N J Olson, Richard B. Pearson, David S. Needleman, Mary Y. Hurwitz, Bruce E. Kemp, Anthony R. Means	1990	175
20	Dysregulation of the basal RNA polymerase transcription apparatus in cancer Nature reviews. Cancer ·Megan J. Bywater, Richard B. Pearson, Grant A. McArthur, Ross D. Hannan	2013	174

About Richard B. Pearson

Richard B. Pearson is a scholar working on Molecular Biology, Oncology, Cell Biology, Pathology and Forensic Medicine and Pulmonary and Respiratory Medicine, having authored 134 papers that have together received 13.2k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (32 papers), PI3K/AKT/mTOR signaling in cancer (25 papers), RNA modifications and cancer (18 papers), Ubiquitin and proteasome pathways (16 papers), Enzyme Structure and Function (10 papers), Chemical Synthesis and Analysis (10 papers), Cancer-related Molecular Pathways (9 papers) and Genomics and Chromatin Dynamics (9 papers). The work is most often cited by research in Molecular Biology (9.8k citations), Cell Biology (1.6k citations), Cancer Research (1.2k citations), Oncology (2.0k citations) and Aging (126 citations). Richard B. Pearson has collaborated with scholars based in Australia, United States and Switzerland. Frequent co-authors include Bruce E. Kemp, Ross D. Hannan, Katherine M. Hannan, Patrick B. Dennis, George Thomas, Grant A. McArthur, Wayne A. Phillips, Stefano Fumagalli, Harold B.J. Jefferies and Christoph Reinhard. Their work appears in journals such as Journal of Biological Chemistry, Blood, The EMBO Journal, Proceedings of the National Academy of Sciences and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Richard B. Pearson

Richard B. Pearson's Hit Papers

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