Michael V. Sofroniew

51.0k total citations · 27 hit papers
191 papers, 37.4k citations indexed

About

Michael V. Sofroniew is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Neurology. According to data from OpenAlex, Michael V. Sofroniew has authored 191 papers receiving a total of 37.4k indexed citations (citations by other indexed papers that have themselves been cited), including 95 papers in Cellular and Molecular Neuroscience, 60 papers in Molecular Biology and 60 papers in Neurology. Recurrent topics in Michael V. Sofroniew's work include Neurogenesis and neuroplasticity mechanisms (58 papers), Neuroinflammation and Neurodegeneration Mechanisms (56 papers) and Nerve injury and regeneration (46 papers). Michael V. Sofroniew is often cited by papers focused on Neurogenesis and neuroplasticity mechanisms (58 papers), Neuroinflammation and Neurodegeneration Mechanisms (56 papers) and Nerve injury and regeneration (46 papers). Michael V. Sofroniew collaborates with scholars based in United States, United Kingdom and Germany. Michael V. Sofroniew's co-authors include Harry V. Vinters, Joshua E. Burda, Baljit S. Khakh, Yan Ao, Mark A. Anderson, Tetsuya Imura, Ngan Doan, William C. Mobley, Charles L. Howe and Timothy M. O’Shea and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael V. Sofroniew

189 papers receiving 36.8k citations

Hit Papers

Astrocytes: biology and pathology 1994 2026 2004 2015 2009 2009 2016 2004 2014 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Astrocytes: biology and pathology
    2009 3.9k citations Michael V. Sofroniew, Harry V. Vinters profile →
  2. Molecular dissection of reactive astrogliosis and glial scar formation
    2009 2.0k citations Michael V. Sofroniew profile →
  3. Astrocyte scar formation aids central nervous system axon regeneration
    2016 1.3k citations Mark A. Anderson, Joshua E. Burda et al. Nature profile →
  4. Reactive Astrocytes Protect Tissue and Preserve Function after Spinal Cord Injury
    2004 1.2k citations Ngan Doan, Michael V. Sofroniew et al. Journal of Neuroscience profile →
  5. Reactive Gliosis and the Multicellular Response to CNS Damage and Disease
    2014 1.1k citations Joshua E. Burda, Michael V. Sofroniew profile →
  6. Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair
    2001 1.1k citations Michael V. Sofroniew et al. profile →
  7. Astrocyte barriers to neurotoxic inflammation
    2015 902 citations Michael V. Sofroniew profile →
  8. Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice
    1999 866 citations Toby G. Bush, Michael V. Sofroniew et al. profile →
  9. Diversity of astrocyte functions and phenotypes in neural circuits
    2015 851 citations Baljit S. Khakh, Michael V. Sofroniew Nature Neuroscience profile →
  10. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
    2006 824 citations A. Denise R. Garcia, Michael V. Sofroniew et al. profile →
  11. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain
    2004 770 citations A. Denise R. Garcia, Ngan Doan et al. Nature Neuroscience profile →
  12. STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury
    2008 738 citations Tetsuya Imura, Yan Ao et al. Journal of Neuroscience profile →
  13. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.
    1994 644 citations Michael V. Sofroniew et al. profile →
  14. Reactive Astrocytes in Neural Repair and Protection
    2005 612 citations Michael V. Sofroniew profile →
  15. Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury
    2013 611 citations Mark A. Anderson, Michael V. Sofroniew et al. Journal of Neuroscience profile →
  16. Astrocyte roles in traumatic brain injury
    2015 578 citations Joshua E. Burda, Alexander M. Bernstein et al. Experimental Neurology profile →
  17. Astrocytes: a central element in neurological diseases
    2015 577 citations Michael V. Sofroniew, Alexei Verkhratsky et al. profile →
  18. Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury
    2007 565 citations Grégoire Courtine, Yan Ao et al. profile →
  19. Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
    2012 552 citations Michael V. Sofroniew et al. profile →
  20. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input
    2009 517 citations Grégoire Courtine, Yan Ao et al. Nature Neuroscience profile →
  21. Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity
    2020 498 citations Michael V. Sofroniew profile →
  22. Astrogliosis
    2014 466 citations Michael V. Sofroniew profile →
  23. Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
    2014 463 citations Yan Ao, Mark A. Anderson et al. Nature Neuroscience profile →
  24. Cell biology of spinal cord injury and repair
    2017 415 citations Timothy M. O’Shea, Joshua E. Burda et al. profile →
  25. Required growth facilitators propel axon regeneration across complete spinal cord injury
    2018 386 citations Mark A. Anderson, Timothy M. O’Shea et al. Nature profile →
  26. Spinal cord repair: advances in biology and technology
    2019 366 citations Grégoire Courtine, Michael V. Sofroniew profile →
  27. Astrocytes in human central nervous system diseases: a frontier for new therapies
    2023 187 citations Alexei Verkhratsky, Arthur M. Butt et al. Signal Transduction and Targeted Therapy profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Michael V. Sofroniew United States 90 14.0k 11.9k 11.8k 9.0k 4.9k 191 37.4k
Klaus‐Armin Nave Germany 94 11.4k 0.8× 6.3k 0.5× 15.0k 1.3× 9.9k 1.1× 2.5k 0.5× 296 32.1k
V. Hugh Perry United Kingdom 106 10.9k 0.8× 18.9k 1.6× 13.3k 1.1× 4.9k 0.5× 2.1k 0.4× 340 42.4k
Martin E. Schwab Switzerland 101 21.8k 1.6× 5.7k 0.5× 8.7k 0.7× 13.0k 1.4× 9.7k 2.0× 397 35.2k
Michal Schwartz Israel 93 7.7k 0.6× 16.8k 1.4× 7.9k 0.7× 5.6k 0.6× 4.6k 0.9× 301 32.6k
Steven A. Goldman United States 81 11.3k 0.8× 6.2k 0.5× 11.3k 1.0× 9.3k 1.0× 919 0.2× 207 27.9k
Helmut Kettenmann Germany 105 16.5k 1.2× 18.4k 1.5× 14.1k 1.2× 7.4k 0.8× 847 0.2× 372 39.6k
Frank R. Sharp United States 87 7.3k 0.5× 5.4k 0.5× 12.3k 1.0× 2.8k 0.3× 1.2k 0.2× 376 27.7k
Bruce D. Trapp United States 94 8.4k 0.6× 8.3k 0.7× 11.3k 1.0× 8.7k 1.0× 12.1k 2.5× 277 34.3k
Olle Lindvall Sweden 107 23.9k 1.7× 7.8k 0.7× 15.9k 1.4× 15.7k 1.8× 832 0.2× 362 42.7k
José Manuel García‐Verdugo Spain 87 12.8k 0.9× 6.6k 0.5× 18.0k 1.5× 21.5k 2.4× 1.0k 0.2× 310 40.8k

Countries citing papers authored by Michael V. Sofroniew

Since Specialization
Citations

This map shows the geographic impact of Michael V. Sofroniew's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael V. Sofroniew with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael V. Sofroniew more than expected).

Fields of papers citing papers by Michael V. Sofroniew

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael V. Sofroniew. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael V. Sofroniew. The network helps show where Michael V. Sofroniew may publish in the future.

Co-authorship network of co-authors of Michael V. Sofroniew

This figure shows the co-authorship network connecting the top 25 collaborators of Michael V. Sofroniew. A scholar is included among the top collaborators of Michael V. Sofroniew based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael V. Sofroniew. Michael V. Sofroniew is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Skinnider, Michael A., Matthieu Gautier, Claudia Kathe, et al.. (2024). Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica. Nature. 631(8019). 150–163. 34 indexed citations
2.
Gleichman, Amy J., Riki Kawaguchi, Michael V. Sofroniew, & S. Thomas Carmichael. (2023). A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences. Nature Communications. 14(1). 7426–7426. 27 indexed citations
3.
Magaki, Shino, Mohammad Haeri, Zesheng Chen, et al.. (2023). Hyaline protoplasmic astrocytopathy in epilepsy. Neuropathology. 43(6). 441–456. 1 indexed citations
4.
Verkhratsky, Alexei, Arthur M. Butt, Baoman Li, et al.. (2023). Astrocytes in human central nervous system diseases: a frontier for new therapies. Signal Transduction and Targeted Therapy. 8(1). 396–396. 187 indexed citations breakdown →
5.
Mills, William A., Shan Jiang, Ian F. Kimbrough, et al.. (2022). Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age. Nature Communications. 13(1). 1794–1794. 60 indexed citations
6.
Cheng, Yuyan, Yuqin Yin, Alice Zhang, et al.. (2022). Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice. Nature Communications. 13(1). 4418–4418. 35 indexed citations
7.
Burda, Joshua E., Timothy M. O’Shea, Yan Ao, et al.. (2022). Divergent transcriptional regulation of astrocyte reactivity across disorders. Nature. 606(7914). 557–564. 95 indexed citations
8.
Kim, Hyosung, Kun Leng, Jinhee Park, et al.. (2022). Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Nature Communications. 13(1). 6581–6581. 99 indexed citations
9.
Wahane, Shalaka & Michael V. Sofroniew. (2021). Loss-of-function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation. Cell and Tissue Research. 387(3). 337–350. 17 indexed citations
10.
Díaz‐Castro, Blanca, Alexander M. Bernstein, Giovanni Coppola, Michael V. Sofroniew, & Baljit S. Khakh. (2021). Molecular and functional properties of cortical astrocytes during peripherally induced neuroinflammation. Cell Reports. 36(6). 109508–109508. 71 indexed citations
11.
Ren, Yilong, Yan Ao, Timothy M. O’Shea, et al.. (2017). Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. Scientific Reports. 7(1). 41122–41122. 109 indexed citations
12.
Cushman, Jesse D., J. Maldonado, Eunice E. Kwon, et al.. (2012). Juvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories. Frontiers in Behavioral Neuroscience. 6. 3–3. 36 indexed citations
13.
Gregorian, Caroline, Jonathan Nakashima, John J. Ohab, et al.. (2009). PtenDeletion in Adult Neural Stem/Progenitor Cells Enhances Constitutive Neurogenesis. Journal of Neuroscience. 29(6). 1874–1886. 221 indexed citations
14.
Dougherty, Joseph D., Ainhoa García, Ichiro Nakano, et al.. (2005). PBK/TOPK, a Proliferating Neural Progenitor-Specific Mitogen-Activated Protein Kinase Kinase. Journal of Neuroscience. 25(46). 10773–10785. 84 indexed citations
15.
Garcia, A. Denise R., Ngan Doan, Tetsuya Imura, Toby G. Bush, & Michael V. Sofroniew. (2004). GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nature Neuroscience. 7(11). 1233–1241. 770 indexed citations breakdown →
16.
Sofroniew, Michael V., Richard Pannell, Helen Impey, et al.. (2000). The T Cell Oncogene Tal2 Is Necessary for Normal Development of the Mouse Brain. Developmental Biology. 227(2). 533–544. 28 indexed citations
17.
Page, Keith J. & Michael V. Sofroniew. (1996). Chapter 30 The ascending basal forebrain cholinergic system. Progress in brain research. 107. 513–522. 11 indexed citations
18.
Cooper, Jonathan D., Dan Lindholm, & Michael V. Sofroniew. (1994). Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated trka expression in the medial septum of aged rats. Neuroscience. 62(3). 625–629. 109 indexed citations
19.
Broadwell, Richard D. & Michael V. Sofroniew. (1993). Serum Proteins Bypass the Blood-Brain Fluid Barriers for Extracellular Entry to the Central Nervous System. Experimental Neurology. 120(2). 245–263. 269 indexed citations
20.
Sofroniew, Michael V.. (1983). Morphology of Vasopressin and Oxytocin Neurones and Their Central and Vascular Projections. Progress in brain research. 60. 101–114. 283 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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