Michael B. Yaffe

43.7k total citations · 16 hit papers
279 papers, 30.9k citations indexed

About

Michael B. Yaffe is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Michael B. Yaffe has authored 279 papers receiving a total of 30.9k indexed citations (citations by other indexed papers that have themselves been cited), including 200 papers in Molecular Biology, 80 papers in Cell Biology and 41 papers in Oncology. Recurrent topics in Michael B. Yaffe's work include Microtubule and mitosis dynamics (55 papers), Ubiquitin and proteasome pathways (54 papers) and 14-3-3 protein interactions (40 papers). Michael B. Yaffe is often cited by papers focused on Microtubule and mitosis dynamics (55 papers), Ubiquitin and proteasome pathways (54 papers) and 14-3-3 protein interactions (40 papers). Michael B. Yaffe collaborates with scholars based in United States, Canada and United Kingdom. Michael B. Yaffe's co-authors include Lewis C. Cantley, Stephen J. Smerdon, Hans Christian Reinhardt, Andrew E. H. Elia, Drew M. Lowery, Isaac A. Manke, Daniel Lim, Stefano Volinia, Duaa H. Mohammad and Alexandra K. Gardino and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael B. Yaffe

273 papers receiving 30.5k citations

Hit Papers

The Structural Basis for 14-3-3:Phosphopeptide Binding Sp... 1997 2026 2006 2016 1997 2005 2011 2005 2007 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity
    1997 1.4k citations Michael B. Yaffe, Stephen J. Smerdon et al. profile →
  2. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
    2005 853 citations Michael B. Yaffe, Stephen J. Smerdon et al. profile →
  3. The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
    2011 840 citations Seong A. Kang, Kathleen Ottina et al. Science profile →
  4. TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation
    2005 837 citations Jeong‐Ho Hong, Eun Sook Hwang et al. Science profile →
  5. RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
    2007 821 citations Robert A. Grant, Isaac A. Manke et al. profile →
  6. Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism
    1997 654 citations Michael B. Yaffe et al. Science profile →
  7. The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
    2003 617 citations L.F. Haire, Stephen J. Smerdon et al. profile →
  8. How do 14‐3‐3 proteins work? – Gatekeeper phosphorylation and the molecular anvil hypothesis
    2001 567 citations Michael B. Yaffe profile →
  9. Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
    2008 563 citations Michael B. Yaffe et al. profile →
  10. Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates
    2003 561 citations Michael B. Yaffe et al. Science profile →
  11. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
    2008 548 citations Michael B. Yaffe et al. profile →
  12. 14-3-3 Proteins and Survival Kinases Cooperate to Inactivate BAD by BH3 Domain Phosphorylation
    2000 532 citations Michael B. Yaffe et al. Molecular Cell profile →
  13. BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting
    2003 529 citations Isaac A. Manke, Drew M. Lowery et al. Science profile →
  14. Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
    2012 528 citations Peter K. Sorger, Michael B. Yaffe et al. profile →
  15. The PX domains of p47phox and p40phox bind to lipid products of PI(3)K
    2001 509 citations Glenn E. Brown, Michael B. Yaffe et al. profile →
  16. Tissue plasminogen activator (tPA) treatment for COVID‐19 associated acute respiratory distress syndrome (ARDS): A case series
    2020 395 citations Ernest E. Moore, Michael B. Yaffe et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Michael B. Yaffe United States 90 23.8k 7.9k 5.7k 3.0k 2.1k 279 30.9k
Mark A. Lemmon United States 78 18.3k 0.8× 7.1k 0.9× 5.7k 1.0× 2.1k 0.7× 1.3k 0.6× 159 25.5k
Anne‐Claude Gingras Canada 88 25.7k 1.1× 5.5k 0.7× 2.9k 0.5× 2.5k 0.8× 1.8k 0.9× 318 32.0k
Steven A. Carr United States 108 31.7k 1.3× 6.3k 0.8× 5.4k 0.9× 3.5k 1.2× 4.0k 1.9× 372 44.4k
Kevan M. Shokat United States 96 24.3k 1.0× 5.4k 0.7× 6.9k 1.2× 4.0k 1.3× 2.4k 1.1× 305 34.2k
Peter J. Parker United Kingdom 95 25.3k 1.1× 7.6k 1.0× 3.9k 0.7× 3.5k 1.2× 2.0k 1.0× 406 33.7k
Walter Kölch Ireland 81 18.9k 0.8× 3.7k 0.5× 4.5k 0.8× 2.0k 0.7× 2.7k 1.3× 298 25.5k
Susan S. Taylor United States 98 29.1k 1.2× 5.6k 0.7× 3.5k 0.6× 1.5k 0.5× 1.1k 0.5× 462 35.7k
Nikola P. Pavletich United States 65 25.2k 1.1× 3.6k 0.5× 9.2k 1.6× 1.9k 0.6× 3.9k 1.9× 79 30.0k
Richard A. Cerione United States 86 18.1k 0.8× 6.2k 0.8× 3.3k 0.6× 1.7k 0.6× 3.6k 1.7× 311 24.1k
Thomas M. Roberts United States 84 19.6k 0.8× 3.6k 0.5× 7.6k 1.3× 3.4k 1.1× 2.6k 1.2× 309 28.9k

Countries citing papers authored by Michael B. Yaffe

Since Specialization
Citations

This map shows the geographic impact of Michael B. Yaffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael B. Yaffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael B. Yaffe more than expected).

Fields of papers citing papers by Michael B. Yaffe

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael B. Yaffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael B. Yaffe. The network helps show where Michael B. Yaffe may publish in the future.

Co-authorship network of co-authors of Michael B. Yaffe

This figure shows the co-authorship network connecting the top 25 collaborators of Michael B. Yaffe. A scholar is included among the top collaborators of Michael B. Yaffe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael B. Yaffe. Michael B. Yaffe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Dong, Ting, Guangan Hu, Zhongqi Fan, et al.. (2024). Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature Communications. 15(1). 807–807. 24 indexed citations
2.
Segal, Brahm H., Thejaswini Giridharan, A. Nazmul H. Khan, et al.. (2022). Neutrophil interactions with T cells, platelets, endothelial cells, and of course tumor cells. Immunological Reviews. 314(1). 13–35. 38 indexed citations
3.
Joughin, Brian A., Tiffany R. Emmons, Valerie Banner‐Goodspeed, et al.. (2022). Neutrophil heterogeneity and emergence of a distinct population of CD11b/CD18-activated low-density neutrophils after trauma. The Journal of Trauma: Injury, Infection, and Critical Care. 94(2). 187–196. 8 indexed citations
4.
5.
Sriram, Ganapathy, Lauren E. Milling, Yi Wen Kong, et al.. (2021). The injury response to DNA damage in live tumor cells promotes antitumor immunity. Science Signaling. 14(705). eabc4764–eabc4764. 41 indexed citations
6.
Barrett, Christopher D., Achikam Oren-Grinberg, Edward Chao, et al.. (2020). Rescue therapy for severe COVID-19–associated acute respiratory distress syndrome with tissue plasminogen activator: A case series. The Journal of Trauma: Injury, Infection, and Critical Care. 89(3). 453–457. 24 indexed citations
7.
Rohani, Nazanin, Liangliang Hao, Maria S. Alexis, et al.. (2019). Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes. Cancer Research. 79(8). 1952–1966. 181 indexed citations
8.
Yaffe, Michael B.. (2019). Why geneticists stole cancer research even though cancer is primarily a signaling disease. Science Signaling. 12(565). 36 indexed citations
9.
Dreaden, Erik C., Yi Wen Kong, Stephen W. Morton, et al.. (2015). Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle. Clinical Cancer Research. 21(19). 4410–4419. 49 indexed citations
10.
Kang, Seong A., Michael E. Pacold, Christopher Cervantes, et al.. (2013). mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin. Science. 341(6144). 1236566–1236566. 3 indexed citations
11.
12.
Kishi, Kazuhiro, Marcel A.T.M. van Vugt, Kenichi Okamoto, Yasunori Hayashi, & Michael B. Yaffe. (2009). Functional Dynamics of Polo-Like Kinase 1 at the Centrosome. Molecular and Cellular Biology. 29(11). 3134–3150. 77 indexed citations
13.
Yi, Chunling, Erik Wilker, Michael B. Yaffe, Anat Stemmer‐Rachamimov, & Joseph L. Kissil. (2008). Validation of the p21-Activated Kinases as Targets for Inhibition in Neurofibromatosis Type 2. Cancer Research. 68(19). 7932–7937. 55 indexed citations
14.
Edbauer, Dieter, Dongmei Cheng, Duc M. Duong, et al.. (2008). Identification and Characterization of Neuronal Mitogen-activated Protein Kinase Substrates Using a Specific Phosphomotif Antibody. Molecular & Cellular Proteomics. 8(4). 681–695. 33 indexed citations
15.
Yoshida, Satoshi, Keiko Kono, Drew M. Lowery, et al.. (2006). Polo-Like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis. Science. 313(5783). 108–111. 120 indexed citations
16.
Charest, Al, Erik Wilker, Margaret E. McLaughlin, et al.. (2006). ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice. Cancer Research. 66(15). 7473–7481. 120 indexed citations
17.
Hong, Jeong‐Ho, Eun Sook Hwang, Michael T. McManus, et al.. (2005). TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation. Science. 309(5737). 1074–1078. 837 indexed citations breakdown →
18.
Manke, Isaac A., Drew M. Lowery, Anhco Nguyen, & Michael B. Yaffe. (2003). BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting. Science. 302(5645). 636–639. 529 indexed citations breakdown →
19.
Durocher, Daniel, Ian A. Taylor, L.F. Haire, et al.. (2000). The Molecular Basis of FHA Domain:Phosphopeptide Binding Specificity and Implications for Phospho-Dependent Signaling Mechanisms. Molecular Cell. 6(5). 1169–1182. 358 indexed citations
20.
Obata, Toshiyuki, Glenn E. Brown, & Michael B. Yaffe. (2000). MAP kinase pathways activated by stress: The p38 MAPK pathway. Critical Care Medicine. 28(Supplement). N67–N77. 299 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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