Titus J. Boggon

33.8k total citations · 6 hit papers
128 papers, 19.1k citations indexed

About

Titus J. Boggon is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Titus J. Boggon has authored 128 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 74 papers in Molecular Biology, 31 papers in Cell Biology and 28 papers in Oncology. Recurrent topics in Titus J. Boggon's work include Protein Kinase Regulation and GTPase Signaling (26 papers), Enzyme Structure and Function (22 papers) and Vascular Malformations Diagnosis and Treatment (13 papers). Titus J. Boggon is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (26 papers), Enzyme Structure and Function (22 papers) and Vascular Malformations Diagnosis and Treatment (13 papers). Titus J. Boggon collaborates with scholars based in United States, United Kingdom and China. Titus J. Boggon's co-authors include Michael J. Eck, Matthew Meyerson, Bruce E. Johnson, Pasi A. Jänne, Heidi Greulich, Balázs Halmos, Jeffrey C. Lee, Paula Herman, William R. Sellers and J. Guillermo Paez and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Titus J. Boggon

124 papers receiving 18.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

2004 7.5k citations J. Guillermo Paez, Pasi A. Jänne et al. Science profile →
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

2005 3.2k citations Susumu Kobayashi, Titus J. Boggon et al. profile →
Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

2007 904 citations Titus J. Boggon, Heidi Greulich et al. profile →
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

2009 618 citations Taro Hitosugi, Sumin Kang et al. profile →
Structure and regulation of Src family kinases

2004 546 citations Titus J. Boggon, Michael J. Eck profile →
C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms

2002 519 citations Titus J. Boggon, Lawrence Shapiro et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Titus J. Boggon United States	46	9.6k	8.9k	8.5k	3.7k	1.3k	128	19.1k
Jeff Settleman United States	38	10.6k 1.1×	8.5k 1.0×	10.8k 1.3×	5.1k 1.4×	1.2k 1.0×	66	20.5k
Kazuto Nishio Japan	69	7.6k 0.8×	6.2k 0.7×	8.0k 0.9×	3.5k 0.9×	721 0.6×	532	16.2k
Geoffrey I. Shapiro United States	79	12.9k 1.3×	7.8k 0.9×	12.8k 1.5×	3.0k 0.8×	1.6k 1.2×	500	23.0k
Nicola Normanno Italy	63	8.4k 0.9×	5.6k 0.6×	10.5k 1.2×	4.5k 1.2×	875 0.7×	362	18.5k
Yoshitaka Fujii Japan	58	7.7k 0.8×	9.1k 1.0×	8.3k 1.0×	4.0k 1.1×	660 0.5×	439	19.9k
Jeffrey G. Supko United States	43	7.4k 0.8×	7.3k 0.8×	7.6k 0.9×	2.9k 0.8×	467 0.4×	192	16.1k
Jeffrey Settleman United States	72	14.0k 1.5×	7.7k 0.9×	10.4k 1.2×	3.8k 1.0×	3.7k 2.8×	158	23.5k
John V. Heymach United States	79	11.1k 1.2×	10.2k 1.2×	13.6k 1.6×	5.4k 1.5×	624 0.5×	635	25.2k
Frank G. Haluska United States	51	7.9k 0.8×	8.0k 0.9×	10.9k 1.3×	3.0k 0.8×	591 0.5×	138	18.7k
Heidi Greulich United States	31	7.5k 0.8×	9.0k 1.0×	8.6k 1.0×	3.1k 0.8×	391 0.3×	52	15.1k

Countries citing papers authored by Titus J. Boggon

Since Specialization

Citations

This map shows the geographic impact of Titus J. Boggon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Titus J. Boggon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Titus J. Boggon more than expected).

Fields of papers citing papers by Titus J. Boggon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Titus J. Boggon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Titus J. Boggon. The network helps show where Titus J. Boggon may publish in the future.

Co-authorship network of co-authors of Titus J. Boggon

This figure shows the co-authorship network connecting the top 25 collaborators of Titus J. Boggon. A scholar is included among the top collaborators of Titus J. Boggon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Titus J. Boggon. Titus J. Boggon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kettunen, K, Pia Laine, Amy L. Stiegler, et al.. (2025). Novel heterozygous SPI1c.538C>T p.(Leu180Phe) variant causes PU.1 haploinsufficiency leading to agammaglobulinemia. Clinical Immunology. 277. 110503–110503.

Stiegler, Amy L., et al.. (2025). Cancer hotspot mutations rewire ERK2 specificity by selective exclusion of docking interactions. Journal of Biological Chemistry. 301(4). 108348–108348. 1 indexed citations

Bibeau, Jeffrey P., Wenxiang Cao, Hua Jane Lou, et al.. (2024). Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail. Nature Communications. 15(1). 1426–1426. 2 indexed citations

Timberlake, Andrew T., Garrett Allington, Emre Kiziltug, et al.. (2023). De novo variants implicate chromatin modification, transcriptional regulation, and retinoic acid signaling in syndromic craniosynostosis. The American Journal of Human Genetics. 110(5). 846–862. 11 indexed citations

Boggon, Titus J., et al.. (2022). SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP. Nature Communications. 13(1). 4788–4788. 12 indexed citations

Ji, Weidong, Yonghao Li, Yun He, et al.. (2015). AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis. Cancer Research. 75(17). 3492–3504. 13 indexed citations

Fisher, Oriana S., Weizhi Liu, Rong Zhang, et al.. (2014). Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations. Journal of Biological Chemistry. 290(5). 2842–2853. 32 indexed citations

Davis, Matthew J., et al.. (2013). RAC1 ^P29S is a spontaneously activating cancer-associated GTPase. Proceedings of the National Academy of Sciences. 110(3). 912–917. 134 indexed citations

Ha, Byung Hak, Matthew J. Davis, Catherine Chen, et al.. (2012). Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proceedings of the National Academy of Sciences. 109(40). 16107–16112. 66 indexed citations

10.

Fan, Jun, Taro Hitosugi, Tae‐Wook Chung, et al.. (2011). Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD ⁺ Redox Homeostasis in Cancer Cells. Molecular and Cellular Biology. 31(24). 4938–4950. 188 indexed citations

11.

Li, Xiaofeng, Weidong Ji, Rong Zhang, et al.. (2011). Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3). Journal of Biological Chemistry. 286(29). 26138–26147. 32 indexed citations

12.

Petri, Edward T., Andjelka S. Ćelić, Scott D. Kennedy, et al.. (2010). Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca ²⁺ -dependent regulation of polycystin-2 channel activity. Proceedings of the National Academy of Sciences. 107(20). 9176–9181. 61 indexed citations

13.

Bae, Jae Hyun, Titus J. Boggon, Francisco Tomé, et al.. (2010). Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proceedings of the National Academy of Sciences. 107(7). 2866–2871. 63 indexed citations

14.

Yu, Zhiwei, Titus J. Boggon, Susumu Kobayashi, et al.. (2007). Resistance to an Irreversible Epidermal Growth Factor Receptor (EGFR) Inhibitor in EGFR-Mutant Lung Cancer Reveals Novel Treatment Strategies. Cancer Research. 67(21). 10417–10427. 57 indexed citations

15.

Kobayashi, Susumu, Titus J. Boggon, Tajhal Dayaram, et al.. (2005). Gefitinib resistance caused by a secondary mutation of the epidermal growth factor receptor. Cancer Research. 65. 620–621.

16.

Paez, J. Guillermo, Pasi A. Jänne, Jeffrey C. Lee, et al.. (2004). EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy. Science. 304(5676). 1497–1500. 7539 indexed citations breakdown →

17.

Santagata, Sandro, Titus J. Boggon, Cheryl L. Baird, et al.. (2001). G-Protein Signaling Through Tubby Proteins. Science. 292(5524). 2041–2050. 302 indexed citations

18.

Boggon, Titus J. & Lawrence R. Shapiro. (2000). Screening for phasing atoms in protein crystallography. Structure. 8(7). R143–R149. 68 indexed citations

19.

Boggon, Titus J., et al.. (2000). Implication of Tubby Proteins as Transcription Factors by Structure-Based Functional Analysis. Acta Crystallographica Section A Foundations of Crystallography. 56(s1). s263–s263. 13 indexed citations

20.

Dong, Jun, Titus J. Boggon, Naomi E. Chayen, et al.. (1999). Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 Å resolution. Acta Crystallographica Section D Biological Crystallography. 55(4). 745–752. 50 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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