Melanie H. Cobb

44.3k total citations · 14 hit papers
278 papers, 37.1k citations indexed

About

Melanie H. Cobb is a scholar working on Molecular Biology, Cell Biology and Surgery. According to data from OpenAlex, Melanie H. Cobb has authored 278 papers receiving a total of 37.1k indexed citations (citations by other indexed papers that have themselves been cited), including 231 papers in Molecular Biology, 55 papers in Cell Biology and 43 papers in Surgery. Recurrent topics in Melanie H. Cobb's work include Melanoma and MAPK Pathways (102 papers), Protein Kinase Regulation and GTPase Signaling (98 papers) and Pancreatic function and diabetes (42 papers). Melanie H. Cobb is often cited by papers focused on Melanoma and MAPK Pathways (102 papers), Protein Kinase Regulation and GTPase Signaling (98 papers) and Pancreatic function and diabetes (42 papers). Melanie H. Cobb collaborates with scholars based in United States, Germany and Japan. Melanie H. Cobb's co-authors include Elizabeth J. Goldsmith, Megan J. Robinson, Teri G. Boulton, David J. Robbins, Gray W. Pearson, Bing-e Xu, Fred L. Robinson, Mahesh Karandikar, Tara Beers Gibson and Kevin Berman and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Melanie H. Cobb

275 papers receiving 36.4k citations

Hit Papers

Mitogen-Activated Protein... 1983 2026 1997 2011 2001 1997 1991 1995 2007 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
    2001 3.4k citations Gray W. Pearson, Tara Beers Gibson et al. profile →
  2. Mitogen-activated protein kinase pathways
    1997 2.2k citations Megan J. Robinson, Melanie H. Cobb Current Opinion in Cell Biology profile →
  3. ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
    1991 1.7k citations Teri G. Boulton, David J. Robbins et al. profile →
  4. How MAP Kinases Are Regulated
    1995 1.6k citations Melanie H. Cobb, Elizabeth J. Goldsmith Journal of Biological Chemistry profile →
  5. Differential regulation and properties of MAPKs
    2007 1.2k citations Melanie H. Cobb et al. profile →
  6. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.
    1992 779 citations Melanie H. Cobb et al. Molecular Biology of the Cell profile →
  7. MAP kinase pathways
    1999 739 citations Melanie H. Cobb profile →
  8. MAP Kinases
    2001 704 citations Tara Beers Gibson, Gray W. Pearson et al. profile →
  9. Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation
    1997 611 citations Melanie H. Cobb, Elizabeth J. Goldsmith et al. profile →
  10. An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control
    1990 600 citations Teri G. Boulton, Melanie H. Cobb et al. profile →
  11. ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.
    1995 584 citations Melanie H. Cobb et al. profile →
  12. Phosphorylation of the MAP Kinase ERK2 Promotes Its Homodimerization and Nuclear Translocation
    1998 576 citations Megan J. Robinson, Elizabeth J. Goldsmith et al. profile →
  13. Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution
    1994 500 citations David J. Robbins, Melanie H. Cobb et al. profile →
  14. Phosphorylation activates the insulin receptor tyrosine protein kinase.
    1983 485 citations Melanie H. Cobb et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Melanie H. Cobb United States 93 27.3k 5.7k 5.6k 3.9k 3.5k 278 37.1k
Brian A. Hemmings Switzerland 102 33.2k 1.2× 7.2k 1.3× 5.1k 0.9× 3.8k 1.0× 3.4k 1.0× 313 42.4k
Joseph Avruch United States 95 29.1k 1.1× 8.6k 1.5× 4.5k 0.8× 3.8k 1.0× 3.4k 1.0× 189 38.2k
Peter J. Parker United Kingdom 95 25.3k 0.9× 7.6k 1.3× 3.9k 0.7× 3.5k 0.9× 2.0k 0.6× 406 33.7k
Eisuke Nishida Japan 104 26.9k 1.0× 9.9k 1.7× 4.7k 0.8× 3.2k 0.8× 3.0k 0.9× 332 37.5k
James R. Woodgett Canada 108 35.7k 1.3× 5.8k 1.0× 5.8k 1.1× 4.8k 1.3× 4.4k 1.3× 293 47.6k
Michael N. Hall Switzerland 108 34.3k 1.3× 6.7k 1.2× 3.1k 0.6× 3.7k 1.0× 3.5k 1.0× 246 44.9k
Enrique Rozengurt United Kingdom 99 22.2k 0.8× 5.2k 0.9× 5.1k 0.9× 2.4k 0.6× 2.8k 0.8× 504 32.9k
John Blenis United States 101 39.2k 1.4× 6.3k 1.1× 8.2k 1.5× 6.5k 1.7× 5.6k 1.6× 222 51.9k
Yukiko Gotoh Japan 75 19.2k 0.7× 3.9k 0.7× 3.8k 0.7× 2.5k 0.6× 2.8k 0.8× 153 25.8k
Johannes L. Bos Netherlands 92 25.6k 0.9× 4.8k 0.9× 11.1k 2.0× 3.1k 0.8× 5.2k 1.5× 246 39.6k

Countries citing papers authored by Melanie H. Cobb

Since Specialization
Citations

This map shows the geographic impact of Melanie H. Cobb's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Melanie H. Cobb with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Melanie H. Cobb more than expected).

Fields of papers citing papers by Melanie H. Cobb

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Melanie H. Cobb. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Melanie H. Cobb. The network helps show where Melanie H. Cobb may publish in the future.

Co-authorship network of co-authors of Melanie H. Cobb

This figure shows the co-authorship network connecting the top 25 collaborators of Melanie H. Cobb. A scholar is included among the top collaborators of Melanie H. Cobb based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Melanie H. Cobb. Melanie H. Cobb is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cobb, Melanie H., et al.. (2025). ERK1/2-MAPK signaling: Metabolic, organellar, and cytoskeletal interactions. Current Opinion in Cell Biology. 95. 102526–102526. 2 indexed citations
2.
Taylor, Clinton A., et al.. (2023). ERK2 Mutations Affect Interactions, Localization, and Dimerization. Biochemistry. 62(9). 1433–1442. 2 indexed citations
3.
Jung, Ji-Ung & Melanie H. Cobb. (2023). WNK1 controls endosomal trafficking through TRIM27-dependent regulation of actin assembly. Proceedings of the National Academy of Sciences. 120(25). e2300310120–e2300310120. 9 indexed citations
4.
Humphreys, John M., Radha Akella, Haixia He, et al.. (2023). Hydrostatic Pressure Sensing by WNK kinases. Molecular Biology of the Cell. 34(11). ar109–ar109. 4 indexed citations
5.
Wang, Yuan, Yi M. Weaver, Svetlana Earnest, et al.. (2023). Modulating p38 MAPK signaling by proteostasis mechanisms supports tissue integrity during growth and aging. Nature Communications. 14(1). 4543–4543. 20 indexed citations
6.
Binns, Derk D., Magdalena Grzemska, Luiz F. Barella, et al.. (2022). Small Molecule-mediated Insulin Hypersecretion Induces Transient ER Stress Response and Loss of Beta Cell Function. Endocrinology. 163(7). 2 indexed citations
7.
Jung, Ji-Ung, Pravat Kumar Parida, Tuyen T. Dang, et al.. (2021). WNK1 Enhances Migration and Invasion in Breast Cancer Models. Molecular Cancer Therapeutics. 20(10). 1800–1808. 33 indexed citations
8.
Kalwat, Michael A. & Melanie H. Cobb. (2019). Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate. Journal of Visualized Experiments. 5 indexed citations
9.
Borromeo, Mark D., Trisha K. Savage, Rahul K. Kollipara, et al.. (2016). ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs. Cell Reports. 16(5). 1259–1272. 318 indexed citations
10.
Dyachok, Julia, et al.. (2016). Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism. Journal of Biological Chemistry. 291(43). 22414–22426. 55 indexed citations
11.
Chamberlain, Chester E., David Scheel, Kathleen McGlynn, et al.. (2014). Menin determines K-RAS proliferative outputs in endocrine cells. Journal of Clinical Investigation. 124(9). 4093–4101. 55 indexed citations
12.
Earnest, Svetlana, Steve Stippec, Xiaofeng Guo, et al.. (2013). Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals. Proceedings of the National Academy of Sciences. 110(47). 18826–18831. 23 indexed citations
13.
Dioum, Elhadji M., Jihan K. Osborne, Sean C. Goetsch, et al.. (2011). A small molecule differentiation inducer increases insulin production by pancreatic β cells. Proceedings of the National Academy of Sciences. 108(51). 20713–20718. 37 indexed citations
14.
Yazicioglu, Mustafa N., et al.. (2007). Mutations in ERK2 Binding Sites Affect Nuclear Entry. Journal of Biological Chemistry. 282(39). 28759–28767. 43 indexed citations
15.
Anselmo, Anthony, Svetlana Earnest, Wei Chen, et al.. (2006). WNK1 and OSR1 regulate the Na + , K + , 2Cl − cotransporter in HeLa cells. Proceedings of the National Academy of Sciences. 103(29). 10883–10888. 152 indexed citations
16.
Chen, Zhui & Melanie H. Cobb. (2006). Activation of MEKK1 by Rho GTPases. Methods in enzymology on CD-ROM/Methods in enzymology. 406. 468–478. 5 indexed citations
17.
Gibson, Tara Beers, Michael C. Lawrence, Bridgette January, et al.. (2003). Regulation of ERK1 and ERK2 by Glucose and Peptide Hormones in Pancreatic β Cells. Journal of Biological Chemistry. 278(35). 32517–32525. 108 indexed citations
18.
Cobb, Melanie H., Shuichan Xu, Mangeng Cheng, et al.. (1996). Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways. Advances in pharmacology. 36. 49–65. 24 indexed citations
19.
Whitehurst, Charles E., Teri G. Boulton, Melanie H. Cobb, & T D Geppert. (1992). Extracellular signal-regulated kinases in T cells. Anti-CD3 and 4 β-phorbol 12-myristate 13-acetate-induced phosphorylation and activation. The Journal of Immunology. 148(10). 3230–3237. 89 indexed citations
20.
Cobb, Melanie H., Garland R. Marshall, & Wyrta Heagy. (1978). Proposed conformation of glutamic acid bound to the GSH receptor. Federation Proceedings. 37(6). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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