Charles S. Craik

31.3k total citations · 1 hit paper
344 papers, 19.6k citations indexed

About

Charles S. Craik is a scholar working on Molecular Biology, Oncology and Infectious Diseases. According to data from OpenAlex, Charles S. Craik has authored 344 papers receiving a total of 19.6k indexed citations (citations by other indexed papers that have themselves been cited), including 181 papers in Molecular Biology, 84 papers in Oncology and 57 papers in Infectious Diseases. Recurrent topics in Charles S. Craik's work include Peptidase Inhibition and Analysis (57 papers), Protease and Inhibitor Mechanisms (46 papers) and HIV Research and Treatment (39 papers). Charles S. Craik is often cited by papers focused on Peptidase Inhibition and Analysis (57 papers), Protease and Inhibitor Mechanisms (46 papers) and HIV Research and Treatment (39 papers). Charles S. Craik collaborates with scholars based in United States, Germany and Czechia. Charles S. Craik's co-authors include John J. Perona, William J. Rutter, Robert J. Fletterick, Jennifer L. Harris, Sami Mahrus, James H. McKerrow, Francesco Leonetti, Jonathan A. Ellman, Lilia M. Babé and Youngchool Choe and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Charles S. Craik

337 papers receiving 19.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural basis of substrate specificity in the serine proteases

1995 695 citations Charles S. Craik et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Charles S. Craik United States	76	10.6k	3.4k	2.3k	2.2k	2.0k	344	19.6k
Matthew Bogyo United States	80	12.0k 1.1×	4.7k 1.4×	1.1k 0.5×	2.9k 1.3×	2.7k 1.4×	300	21.5k
David P. Fairlie Australia	87	13.9k 1.3×	3.8k 1.1×	1.8k 0.8×	7.0k 3.2×	2.1k 1.0×	466	28.6k
E. Yvonne Jones United Kingdom	87	10.2k 1.0×	2.4k 0.7×	2.4k 1.1×	8.5k 3.9×	1.8k 0.9×	282	22.5k
Gary J. Kapral United States	11	25.5k 2.4×	2.7k 0.8×	3.0k 1.3×	2.7k 1.2×	2.3k 1.2×	12	35.1k
Dennis A. Carson United States	88	11.4k 1.1×	5.7k 1.7×	1.8k 0.8×	11.1k 5.1×	3.0k 1.5×	467	29.3k
Nigel W. Moriarty United States	35	26.8k 2.5×	2.9k 0.9×	3.2k 1.4×	2.9k 1.3×	2.4k 1.2×	77	37.9k
Jeffrey J. Headd United States	17	28.2k 2.7×	3.1k 0.9×	3.3k 1.5×	3.0k 1.4×	2.5k 1.3×	20	39.1k
Piet Gros Netherlands	75	19.8k 1.9×	7.7k 2.3×	3.3k 1.5×	5.7k 2.6×	2.4k 1.2×	251	34.7k
Vito Türk Slovenia	85	12.8k 1.2×	4.3k 1.3×	800 0.4×	2.5k 1.2×	2.3k 1.1×	424	25.3k
Vincent B. Chen United States	16	25.3k 2.4×	2.7k 0.8×	3.0k 1.4×	2.7k 1.2×	2.3k 1.2×	22	35.1k

Countries citing papers authored by Charles S. Craik

Since Specialization

Citations

This map shows the geographic impact of Charles S. Craik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles S. Craik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles S. Craik more than expected).

Fields of papers citing papers by Charles S. Craik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles S. Craik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles S. Craik. The network helps show where Charles S. Craik may publish in the future.

Co-authorship network of co-authors of Charles S. Craik

This figure shows the co-authorship network connecting the top 25 collaborators of Charles S. Craik. A scholar is included among the top collaborators of Charles S. Craik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charles S. Craik. Charles S. Craik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Craik, Charles S., et al.. (2025). Identifying protease-activated targets and exploring therapeutic applications. Expert Opinion on Therapeutic Targets. 29(10). 687–701.

Pandey, Apurva, Simon J. Cleary, Mark R. Looney, et al.. (2024). Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography. ACS Infectious Diseases. 10(6). 2108–2117. 2 indexed citations

Pandey, Apurva, Lieza M. Chan, Chayanid Ongpipattanakul, et al.. (2024). Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies. Cancer Research. 85(2). 329–341. 5 indexed citations

Rashmi, Priyanka, Tara K. Sigdel, Izabella Damm, et al.. (2023). Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors. Annals of Translational Medicine. 11(9). 315–315. 6 indexed citations

Meyer, Bjoern, Jeanne Chiaravalli, Stacy Gellenoncourt, et al.. (2021). Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential. Nature Communications. 12(1). 5553–5553. 75 indexed citations

O’Donnell, Henry, et al.. (2021). Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens. Journal of Medicinal Chemistry. 64(23). 17530–17539. 25 indexed citations

Lindan, Christina, Manisha Desai, Derek Boothroyd, et al.. (2021). Design of a population-based longitudinal cohort study of SARS-CoV-2 incidence and prevalence among adults in the San Francisco Bay Area. Annals of Epidemiology. 67. 81–100. 8 indexed citations

Lohse, Matthew B., et al.. (2020). An Opaque Cell-Specific Expression Program of Secreted Proteases and Transporters Allows Cell-Type Cooperation in Candida albicans. Genetics. 216(2). 409–429. 6 indexed citations

Vondrášek, Jiřı́, Lucie Marešová, Martin Hubálek, et al.. (2018). SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. PLoS neglected tropical diseases. 12(4). e0006446–e0006446. 27 indexed citations

10.

Sharib, Jeremy, Dana A. Dominguez, Nilotpal Roy, et al.. (2017). Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts. Clinical Cancer Research. 23(16). 4865–4874. 31 indexed citations

11.

Homer, Christina M., Alexi I. Goranov, Starlynn Clarke, et al.. (2016). Intracellular Action of a Secreted Peptide Required for Fungal Virulence. Cell Host & Microbe. 19(6). 849–864. 64 indexed citations

12.

LeBeau, Aaron M., Natalia Sevillano, Kate Markham, et al.. (2015). Imaging Active Urokinase Plasminogen Activator in Prostate Cancer. Cancer Research. 75(7). 1225–1235. 25 indexed citations

13.

Lucas, Jared M., Cynthia Heinlein, Tom Kim, et al.. (2014). The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis. Cancer Discovery. 4(11). 1310–1325. 338 indexed citations

14.

Lasater, Elisabeth A., Cheryl Tajon, Juan A. Osés-Prieto, et al.. (2013). MEK-Dependent Negative Feedback Underlies BCR–ABL-Mediated Oncogene Addiction. Cancer Discovery. 4(2). 200–215. 27 indexed citations

15.

Trivedi, Neil N., Wilfred W. Raymond, Rajkumar Ganesan, et al.. (2013). Mutational Tail Loss Is an Evolutionary Mechanism for Liberating Marapsins and Other Type I Serine Proteases from Transmembrane Anchors. Journal of Biological Chemistry. 288(15). 10588–10598. 5 indexed citations

16.

Darragh, Molly R., Eric L. Schneider, Jianlong Lou, et al.. (2010). Tumor Detection by Imaging Proteolytic Activity. Cancer Research. 70(4). 1505–1512. 40 indexed citations

17.

Marnett, Alan B., Anson M. Nomura, Nobuhisa Shimba, Paul R. Ortiz de Montellano, & Charles S. Craik. (2004). Communication between the active sites and dimer interface of a herpesvirus protease revealed by a transition-state inhibitor. Proceedings of the National Academy of Sciences. 101(18). 6870–6875. 35 indexed citations

18.

Babé, Lilia M., et al.. (1997). Obstruction of HIV-1 Particle Release by Interferon-α Occurs Before Viral Protease Processing and Is Independent of Envelope Glycoprotein. Journal of Interferon & Cytokine Research. 17(5). 287–293. 7 indexed citations

19.

Cleland, Jeffrey L. & Charles S. Craik. (1996). Protein engineering : principles and practice. 85 indexed citations

20.

Sigal, Elliott, Charles S. Craik, E. Highland, et al.. (1988). Molecular cloning and primary structure of human 15-lipoxygenase. Biochemical and Biophysical Research Communications. 157(2). 457–464. 181 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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