Jennifer O’Neil

5.0k total citations · 2 hit papers
36 papers, 3.4k citations indexed

About

Jennifer O’Neil is a scholar working on Molecular Biology, Oncology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Jennifer O’Neil has authored 36 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 16 papers in Oncology and 9 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Jennifer O’Neil's work include Acute Lymphoblastic Leukemia research (9 papers), CAR-T cell therapy research (8 papers) and Acute Myeloid Leukemia Research (6 papers). Jennifer O’Neil is often cited by papers focused on Acute Lymphoblastic Leukemia research (9 papers), CAR-T cell therapy research (8 papers) and Acute Myeloid Leukemia Research (6 papers). Jennifer O’Neil collaborates with scholars based in United States, Canada and United Kingdom. Jennifer O’Neil's co-authors include A. Thomas Look, Michelle A. Kelliher, Christopher Winter, Jon C. Aster, Peter R. Strack, Giulio Draetta, Donna Neuberg, Xiaoyang Wu, Christopher Leo and Jiang Zhu and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine and Journal of Clinical Oncology.

In The Last Decade

Jennifer O’Neil

36 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

2006 639 citations Teresa Palomero, Wei Keat Lim et al. Proceedings of the National Academy of Sciences profile →
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

2007 523 citations Jennifer O’Neil, Jonathan Grim et al. The Journal of Experimental Medicine profile →

Peers

Countries citing papers authored by Jennifer O’Neil

Since Specialization

Citations

This map shows the geographic impact of Jennifer O’Neil's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jennifer O’Neil with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jennifer O’Neil more than expected).

Fields of papers citing papers by Jennifer O’Neil

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jennifer O’Neil. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jennifer O’Neil. The network helps show where Jennifer O’Neil may publish in the future.

Co-authorship network of co-authors of Jennifer O’Neil

This figure shows the co-authorship network connecting the top 25 collaborators of Jennifer O’Neil. A scholar is included among the top collaborators of Jennifer O’Neil based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jennifer O’Neil. Jennifer O’Neil is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer 2023 ·Journal for ImmunoTherapy of Cancer ·(unknown), Miso Park, Magali Pederzoli-Ribeil, Uğur Eskiocak, (unknown), (unknown), M. A. McLaughlin, (unknown), (unknown), Zhen Liu, Benjamin Nicholson, (unknown), Huawei Qiu, Tim Clackson, Rónán C. O’Hagan, Ulrich Rodeck, Margaret Karow, Jennifer O’Neil, John C. Williams	8
2	Tumor-selective activity of XTX202, a protein-engineered IL-2, in mice without peripheral toxicities in nonhuman primates. 2021 ·Journal of Clinical Oncology ·Jennifer O’Neil, (unknown), (unknown), (unknown), Manoussa Fanny, Justin Greene, Megan McLaughlin, (unknown), Rebekah K. O’Donnell, Huawei Qiu, Benjamin Nicholson, William Avery, Rónán C. O’Hagan	15
3	587 Tumor-activated Fc-engineered anti-CTLA-4 monoclonal antibody, XTX101, demonstrates tumor-selective PD and efficacy in preclinical models 2020 ·SHILAP Revista de lepidopterología ·(unknown), (unknown), Minjie Zhang, (unknown), Uğur Eskiocak, M. A. McLaughlin, (unknown), Magali Pederzoli-Ribeil, Miso Park, John C. Williams, Margaret Karow, Jennifer O’Neil, Timothy Piers Clackson, Rónán C. O’Hagan	2
4	Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations 2019 ·The Journal of Organic Chemistry ·Zachary Z. Brown, Claudio Mapelli, Iman Farasat, (unknown), S.A. Johnson, Federica Orvieto, Alessia Santoprete, Elisabetta Bianchi, (unknown), (unknown), Xiaohong Zhu, Mark J. Demma, Brian M. Lacey, Keith A. Canada, R. M. Garbaccio, Jennifer O’Neil, Abbas M. Walji	19
5	Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene 2019 ·Molecular and Cellular Biology ·Mark J. Demma, Claudio Mapelli, (unknown), Smaranda Bodea, Benjamin Ruprecht, Sarah Javaid, Derek Wiswell, Eric S. Muise, Shiying Chen, (unknown), Federica Orvieto, Alessia Santoprete, (unknown), (unknown), Enrique Escandón, Brian E. Hall, Kallol Ray, Abbas M. Walji, Jennifer O’Neil	77
6	Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass Spectrometry 2018 ·SLAS DISCOVERY ·Deborah A. Flusberg, Noreen F. Rizvi, (unknown), Christine L. Andrews, P Saradjian, (unknown), Patrick J. Curran, (unknown), Solomon D. Kattar, G. Smith, Peter J. Dandliker, Elliott Nickbarg, Jennifer O’Neil	22
7	High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide 2016 ·Molecular Cancer Therapeutics ·Amy D. Guertin, Jennifer O’Neil, Alexander Stoeck, Joseph A. Reddy, Răzvan Cristescu, Brian B. Haines, (unknown), Ryan Dorton, (unknown), Melissa Nelson, Marilynn Vetzel, Serguei Lejnine, Michael Nebozhyn, Theresa Zhang, Andrey Loboda, (unknown), Emmett V. Schmidt, Isabelle Dussault, Christopher P. Leamon	16
8	An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies 2016 ·Molecular Cancer Therapeutics ·Jennifer O’Neil, Yair Benita, Igor Feldman, Mélissa Chénard, Brian S. Roberts, Yaping Liu, Jing Li, Astrid M. Kral, Serguei Lejnine, Andrey Loboda, William T. Arthur, Răzvan Cristescu, Brian B. Haines, Christopher Winter, Theresa Zhang, Andrew Bloecher, Stuart D. Shumway	227
9	Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells 2009 ·Cancer Research ·Sudhir Rao, Jennifer O’Neil, (unknown), James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio Draetta, A. Thomas Look, Peter R. Strack, Christopher Winter	114
10	Alu elements mediate MYB gene tandem duplication in human T-ALL 2007 ·The Journal of Experimental Medicine ·Jennifer O’Neil, Joëlle Tchinda, Alejandro Gutiérrez, Lisa A. Moreau, Richard S. Maser, Kwok‐Kin Wong, Wei Li, Keith McKenna, (unknown), Bin Feng, Donna Neuberg, Lewis B. Silverman, Daniel J. DeAngelo, Jeffery L. Kutok, Rodney Rothstein, Ronald A. DePinho, Lynda Chin, Charles Lee, A. Thomas Look	75
11	Mechanisms of transcription factor deregulation in lymphoid cell transformation 2007 ·Oncogene ·Jennifer O’Neil, A. Thomas Look	91
12	Apoptosis in T Cell Acute Lymphoblastic Leukemia Cells after Cell Cycle Arrest Induced by Pharmacological Inhibition of Notch Signaling 2007 ·Chemistry & Biology ·Huw D. Lewis, (unknown), Peter R. Strack, (unknown), Jennifer O’Neil, (unknown), Andrew Madin, (unknown), A. Thomas Look, Nancy E. Kohl, Giulio Draetta, Timothy Harrison, Julie Kerby, Mark S. Shearman, Dirk Beher	110
13	FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors breakdown → 2007 ·The Journal of Experimental Medicine ·Jennifer O’Neil, Jonathan Grim, Peter R. Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James C.H. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters, Giulio Draetta, Rosalie C. Sears, Bruce E. Clurman, A. Thomas Look	523
14	NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth breakdown → 2006 ·Proceedings of the National Academy of Sciences ·Teresa Palomero, Wei Keat Lim, Duncan T. Odom, Maria Luisa Sulis, Pedro J. Real, Adam A. Margolin, Kelly Barnes, Jennifer O’Neil, Donna Neuberg, Andrew P. Weng, Jon C. Aster, François Sigaux, Jean Soulier, A. Thomas Look, Richard A. Young, Andrea Califano, Adolfo A. Ferrando	639
15	Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias 2006 ·Leukemia ·Teresa Palomero, Keith McKenna, Jennifer O’Neil, Ilene Galinsky, Richard M. Stone, Kazumi Suzukawa, Eftichia Stiakaki, Maria Kalmanti, Edward A. Fox, Michael A. Caligiuri, Jon C. Aster, A. Thomas Look, Adolfo A. Ferrando	51
16	Activating Notch1 mutations in mouse models of T-ALL 2005 ·Blood ·Jennifer O’Neil, Jennifer A. Calvo, Keith McKenna, Veena Krishnamoorthy, Jon C. Aster, Craig H. Bassing, Frederick W. Alt, Michelle A. Kelliher, A. Thomas Look	177
17	TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB 2004 ·Cancer Cell ·Jennifer O’Neil, (unknown), (unknown), Cornelis Murre, Michelle A. Kelliher	152
18	NF-κB activation in premalignant mouse tal-1/scl thymocytes and tumors 2003 ·Blood ·Jennifer O’Neil, Juan‐José Ventura, (unknown), Michelle A. Kelliher	12
19	The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice 2001 ·Oncogene ·Jennifer O’Neil, (unknown), Sarah Oikemus, Michelle A. Kelliher	51
20	Relationship among Antioxidant Activity, Vasodilation Capacity, and Phenolic Content of Red Wines 1999 ·Journal of Agricultural and Food Chemistry ·Jennifer M. Burns, Peter T. Gardner, Jennifer O’Neil, (unknown), Ian Morecroft, Donald B. McPhail, Carolyn E. Lister, D. M. Matthews, Margaret R. MacLean, Michael E. J. Lean, Garry G. Duthie, Alan Crozier	383

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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