A. Thomas Look

57.1k citations

385 papers · 40.5k indexed · 14 hit papers · h-index 101

Impact in

Hematology top 0.02%
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
Cancer Research top 0.1%
- Cancer, Hypoxia, and Metabolism

Papers in

Hematology 135
- Acute Myeloid Leukemia Research 102
- Chronic Myeloid Leukemia Treatments 45
Neurology 77
- Neuroblastoma Research and Treatments 75

Co-authors: John P. Kanki Adolfo A. Ferrando Ching‐Hon Pui Clemens Grabher Charles J. Sherr Martine F. Roussel Jon C. Aster David N. Shapiro
Journals: Blood (93 papers)Leukemia (19 papers)Journal of Clinical Oncology (19 papers)British Journal of Haematology (12 papers)Proceedings of the National Academy of Sciences (11 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

A. Thomas Look

383 papers receiving 39.7k citations

Hit Papers

14 papers align trajectories log scale

An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element 2014 · 538 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2014 Science
2009 Nature
2008 The Lancet
2007 The Journal of Experimental Medicine
2006 Proceedings of the National Academy of Sciences
2004 Immunity
2004 Science
2002 Cancer Cell
2000 Nature Medicine
1997 Science
1994 Science
1992 Nature
1985 Cell
1984 New England Journal of Medicine

Peers

Countries citing papers authored by A. Thomas Look

Since Specialization

Citations

This map shows the geographic impact of A. Thomas Look's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Thomas Look with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Thomas Look more than expected).

Fields of papers citing papers by A. Thomas Look

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Thomas Look. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Thomas Look. The network helps show where A. Thomas Look may publish in the future.

Co-authorship network

The 25 scholars most cited alongside A. Thomas Look, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with A. Thomas Look Line = papers co-authored together A. Thomas Look links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	p53 Pathway Inactivation Drives SMARCB1 -deficient p53 -wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition Molecular Cancer Therapeutics ·Felix Oppel, Joanne Barker, Scherbel Al, Mark W. Zimmerman, Matthias Schürmann, 泽边, Peter Goon, Susan Chi, Jon C. Aster, Holger Sudhoff, A. Thomas Look	2022	4
2	Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss Oncogene ·Shuning He, Mark W. Zimmerman, 中村琢弥, Alla Berezovskaya, Julia Etchin, Megan W. Martel, Ольга Николаевна Полисадова, Changbin Jing, Ellen van Rooijen, Charles K. Kaufman, Scott J. Rodig, Leonard I. Zon, E. Elizabeth Patton, Marc R. Mansour, A. Thomas Look	2021	4
3	Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma Cancer Research ·Nicole Anderson, Xiaodan Qin, Jennifer M. Finan, Ari Rehfeld, Sankalita Chakraborty, Rindert Missiaen, Nicolas Skuli, A.I. Gavril'chenko, Andrey Coffey, Ting Tao, Shizhen Zhu, Itzhak Nissim, A. Thomas Look, Guoliang Qing, M. Celeste Simon, Hui Feng	2021	44
4	Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry Nature Genetics ·Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia, Brian J. Abraham, Amanda Balboni Iniguez, Nina Weichert‐Leahey, Shuning He, John M. Krill-Burger, David E. Root, Francisca Vázquez, Aviad Tsherniak, William C. Hahn, Todd R. Golub, Richard A. Young, A. Thomas Look, Kimberly Stegmaier	2018	145
5	MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification Cancer Discovery ·Mark W. Zimmerman, Yu Liu, Shuning He, Adam D. Durbin, Brian J. Abraham, John Easton, Ying Shao, Beisi Xu, Shizhen Zhu, Xiaoling Zhang, Zhaodong Li, Nina Weichert‐Leahey, Richard A. Young, Jinghui Zhang, A. Thomas Look	2017	147
6	Zebrafish B Cell Development without a Pre–B Cell Stage, Revealed by CD79 Fluorescence Reporter Transgenes The Journal of Immunology ·अर्जुनसिंह पंवार, Yuesheng Li, Susan A. Shinton, Jennifer Rhodes, Lingjuan Tang, Hui Feng, Cicely A. Jette, A. Thomas Look, Kyoko Hayakawa, Richard R. Hardy	2017	36
7	An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element Science ·Marc R. Mansour, Brian J. Abraham, Lars Anders, Alla Berezovskaya, Alejandro Gutiérrez, Adam D. Durbin, Julia Etchin, Lee N. Lawton, Stephen E. Sallan, Lewis B. Silverman, Mignon L. Loh, Stephen P. Hunger, Takaomi Sanda, Richard A. Young, A. Thomas Look Hit paper breakdown →	2014	538
8	Absence of Biallelic TCR γ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia Journal of Clinical Oncology ·Alejandro Gutiérrez, Suzanne E. Dahlberg, Donna Neuberg, Jianhua Zhang, Ruta Grebliunaite, Takaomi Sanda, Alexei Protopopov, Valeria Tosello, Jeffery L. Kutok, Richard A. Larson, Michael J. Borowitz, Mignon L. Loh, Adolfo A. Ferrando, Stuart S. Winter, Charles G. Mullighan, Lewis B. Silverman, Lynda Chin, Stephen P. Hunger, Stephen E. Sallan, A. Thomas Look	2010	69
9	mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues British Journal of Haematology ·Blaine W. Robinson, Giuseppe Germanò, Yuanquan Song, Ferial Tri Aura, Marion O. Scott, Arun Uttam Patil, Natascia Tiso, Francesco Argenton, Giuseppe Basso, Jennifer Rhodes, John P. Kanki, A. Thomas Look, Rita J. Balice‐Gordon, Carolyn A. Felix	2010	5
10	Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells Cancer Research ·Sudhir Rao, Jennifer O’Neil, William Edward Byrne, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio Draetta, A. Thomas Look, Peter R. Strack, Christopher Winter	2009	114
11	Comparison of Primary Neuroblastoma Tumors and Derivative Early-Passage Cell Lines Using Genome-Wide Single Nucleotide Polymorphism Array Analysis Cancer Research ·Samuel L. Volchenboum, Cheng Li, Shuli Li, Edward F. Attiyeh, C. Patrick Reynolds, John M. Maris, A. Thomas Look, Rani E. George	2009	21
12	Clinical Significance of MYCN Amplification and Ploidy in Favorable-Stage Neuroblastoma: A Report From the Children's Oncology Group Journal of Clinical Oncology ·Jennifer Schneiderman, Wendy B. London, Garrett M. Brodeur, Robert P. Castleberry, A. Thomas Look, Susan L. Cohn	2008	50
13	The Effect of a Depth Gradient on the Mating Behavior, Oviposition Site Preference, and Embryo Production in the Zebrafish, Danio rerio Zebrafish ·Anna K. Sessa, Richard White, Yariv Houvras, Christopher J. Burke, Emily K. Pugach, Barry W. Baker, Rabish Cahandra Shukla, A. Thomas Look, Leonard I. Zon	2008	23
14	Neuroblastoma Cells Isolated from Bone Marrow Metastases Contain a Naturally Enriched Tumor-Initiating Cell Cancer Research ·Loen M. Hansford, Amy E. McKee, Libo Zhang, Rani E. George, J. Ted Gerstle, Paul S. Thorner, Kristen M. Smith, A. Thomas Look, Herman Yeger, Freda D. Miller, Meredith S. Irwin, Carol J. Thiele, David R. Kaplan	2007	132
15	NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth Proceedings of the National Academy of Sciences ·Teresa Palomero, Wei Keat Lim, Duncan T. Odom, Maria Luisa Sulis, Pedro J. Real, Adam A. Margolin, Kelly Barnes, Jennifer O’Neil, Donna Neuberg, Andrew P. Weng, Jon C. Aster, François Sigaux, Jean Soulier, A. Thomas Look, Richard A. Young, Andrea Califano, Adolfo A. Ferrando Hit paper breakdown →	2006	639
16	Outcomes of Children With Intermediate-Risk Neuroblastoma After Treatment Stratified by MYCN Status and Tumor Cell Ploidy Journal of Clinical Oncology ·Rochelle Bagatell, K. W. Wilkinson, Wendy B. London, Susan L. Cohn, A. Thomas Look, Garrett M. Brodeur, Christopher Frantz, Vijay Joshi, Paul S. Thorner, Pejaver V. Rao, Robert P. Castleberry, Laura C. Bowman	2005	59
17	Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia Science ·Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee, John P. Morris, Lewis B. Silverman, Cheryll Sanchez-Irizarry, Stephen C. Blacklow, A. Thomas Look, Jon C. Aster Hit paper breakdown →	2004	2013
18	Myc-Induced T Cell Leukemia in Transgenic Zebrafish Science ·David M. Langenau, David Traver, Adolfo A. Ferrando, Jeffery L. Kutok, Jon C. Aster, John P. Kanki, Shuo Lin, Xiajun Rong, Nikolaus S. Trede, Leonard I. Zon, A. Thomas Look	2003	432
19	Natural History and Biology of Stage A Neuroblastoma: A Pediatric Oncology Group Study The American journal of pediatric hematology/oncology ·Angie M. Schinkel, Wendy B. London, A. Thomas Look, Garrett M. Brodeur, Dale H. Altmiller, Paul S. Thorner, Vijay Joshi, Susan Rowe, F Riebau, E. Ide Smith, Robert P. Castleberry, Susan L. Cohn	2000	70
20	DNA-Binding Specificity and trans -Activating Potential of the Leukemia-Associated E2A-Hepatic Leukemia Factor Fusion Protein Molecular and Cellular Biology ·Toshiya Inaba, Linda H. Shapiro, T. Funabiki, JøSrgen Ovesen, Bart G. Jones, Richard A. Ashmun, A. Thomas Look	1994	13

About A. Thomas Look

A. Thomas Look is a scholar working on Hematology, Neurology, Public Health, Environmental and Occupational Health, Cell Biology and Cancer Research, having authored 385 papers that have together received 40.5k indexed citations. Recurring topics across this work include Acute Lymphoblastic Leukemia research (112 papers), Acute Myeloid Leukemia Research (102 papers), Neuroblastoma Research and Treatments (75 papers), Zebrafish Biomedical Research Applications (46 papers), Chronic Myeloid Leukemia Treatments (45 papers), Epigenetics and DNA Methylation (30 papers), Childhood Cancer Survivors' Quality of Life (24 papers) and RNA Interference and Gene Delivery (20 papers). The work is most often cited by research in Hematology (8.8k citations), Cancer Research (5.4k citations), Neurology (5.3k citations), Immunology (7.0k citations) and Cell Biology (5.2k citations). A. Thomas Look has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include John P. Kanki, Adolfo A. Ferrando, Ching‐Hon Pui, Clemens Grabher, Charles J. Sherr, Martine F. Roussel, Jon C. Aster, David N. Shapiro, Leslie L. Robison and Leonard I. Zon. Their work appears in journals such as Blood, Leukemia, Journal of Clinical Oncology, British Journal of Haematology and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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