R. M. Garbaccio

3.3k total citations · 1 hit paper
40 papers, 1.9k citations indexed

About

R. M. Garbaccio is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, R. M. Garbaccio has authored 40 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 21 papers in Organic Chemistry and 7 papers in Pharmacology. Recurrent topics in R. M. Garbaccio's work include Synthetic Organic Chemistry Methods (9 papers), Chemical Synthesis and Analysis (7 papers) and Asymmetric Synthesis and Catalysis (7 papers). R. M. Garbaccio is often cited by papers focused on Synthetic Organic Chemistry Methods (9 papers), Chemical Synthesis and Analysis (7 papers) and Asymmetric Synthesis and Catalysis (7 papers). R. M. Garbaccio collaborates with scholars based in United States, Italy and United Kingdom. R. M. Garbaccio's co-authors include Dale L. Boger, Emma R. Parmee, Christopher W. Boyce, Joel Goldberg, Samuel J. Danishefsky, Paul J. Coleman, Matthew D. Truppo, Richard D. Tillyer, Spencer D. Dreher and Juan C. Alvarez and has published in prestigious journals such as Science, Chemical Reviews and Journal of the American Chemical Society.

In The Last Decade

R. M. Garbaccio

40 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The importance of synthetic chemistry in the pharmaceutical industry

2019 454 citations Kevin R. Campos, Paul J. Coleman et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
R. M. Garbaccio United States	22	1.2k	959	182	130	109	40	1.9k
Mark Searcey United Kingdom	27	837 0.7×	1.2k 1.3×	194 1.1×	324 2.5×	121 1.1×	84	1.9k
Kevin G. Pinney United States	27	1.3k 1.1×	654 0.7×	225 1.2×	272 2.1×	135 1.2×	85	2.0k
Ji‐Wang Chern Taiwan	26	1.1k 0.9×	1.2k 1.2×	157 0.9×	312 2.4×	56 0.5×	116	2.2k
Joel C. Barrish United States	29	1.4k 1.1×	882 0.9×	204 1.1×	301 2.3×	48 0.4×	104	2.3k
Atli Thorarensen United States	24	1.2k 1.0×	749 0.8×	123 0.7×	156 1.2×	48 0.4×	45	2.0k
Zhu‐Jun Yao China	25	1.3k 1.1×	634 0.7×	193 1.1×	139 1.1×	77 0.7×	96	1.8k
Ingrid Schuberth Germany	23	623 0.5×	544 0.6×	109 0.6×	82 0.6×	62 0.6×	36	984
Jean‐Pierre Gesson France	21	852 0.7×	637 0.7×	138 0.8×	186 1.4×	45 0.4×	90	1.4k
Benoı̂t Joseph France	25	1.6k 1.3×	822 0.9×	126 0.7×	282 2.2×	96 0.9×	95	2.3k
Mark G. Saulnier United States	21	954 0.8×	807 0.8×	80 0.4×	173 1.3×	122 1.1×	49	1.7k

Countries citing papers authored by R. M. Garbaccio

Since Specialization

Citations

This map shows the geographic impact of R. M. Garbaccio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. M. Garbaccio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. M. Garbaccio more than expected).

Fields of papers citing papers by R. M. Garbaccio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. M. Garbaccio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. M. Garbaccio. The network helps show where R. M. Garbaccio may publish in the future.

Co-authorship network of co-authors of R. M. Garbaccio

This figure shows the co-authorship network connecting the top 25 collaborators of R. M. Garbaccio. A scholar is included among the top collaborators of R. M. Garbaccio based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. M. Garbaccio. R. M. Garbaccio is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Campos, Kevin R., Paul J. Coleman, Juan C. Alvarez, et al.. (2019). The importance of synthetic chemistry in the pharmaceutical industry. Science. 363(6424). 454 indexed citations breakdown →

Brown, Zachary Z., Claudio Mapelli, Iman Farasat, et al.. (2019). Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations. The Journal of Organic Chemistry. 85(3). 1466–1475. 19 indexed citations

Garbaccio, R. M. & Emma R. Parmee. (2016). The Impact of Chemical Probes in Drug Discovery: A Pharmaceutical Industry Perspective. Cell chemical biology. 23(1). 10–17. 57 indexed citations

Rossi, Michael, Michael J. Kelly, M. E. Layton, et al.. (2016). Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. ACS Medicinal Chemistry Letters. 7(3). 312–317. 8 indexed citations

Barrett, Stephanie E., Marc Abrams, Rob S. Burke, et al.. (2014). An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents. International Journal of Pharmaceutics. 466(1-2). 58–67. 13 indexed citations

Guidry, Erin N., Arash Soheili, Craig A. Parish, et al.. (2014). Improving the In Vivo Therapeutic Index of siRNA Polymer Conjugates through Increasing pH Responsiveness. Bioconjugate Chemistry. 25(2). 296–307. 15 indexed citations

Parmar, Rubina, Eileen S. Walsh, Karen Leander, et al.. (2013). Endosomolytic Bioreducible Poly(amido amine disulfide) Polymer Conjugates for the in Vivo Systemic Delivery of siRNA Therapeutics. Bioconjugate Chemistry. 24(4). 640–647. 33 indexed citations

Brnardic, Edward J., Mark E. Fraley, R. M. Garbaccio, et al.. (2010). 3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts. Bioorganic & Medicinal Chemistry Letters. 20(10). 3129–3133. 30 indexed citations

Garbaccio, R. M., Edward J. Brnardic, Mark E. Fraley, et al.. (2010). Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor. ACS Medicinal Chemistry Letters. 1(8). 406–410. 14 indexed citations

10.

Cox, Christopher D. & R. M. Garbaccio. (2010). Discovery of Allosteric Inhibitors of Kinesin Spindle Protein (KSP) for the Treatment of Taxane-Refractory Cancer: MK-0731 and Analogs. Anti-Cancer Agents in Medicinal Chemistry. 10(9). 697–712. 11 indexed citations

11.

Li, Chunze, Bing Lu, R. M. Garbaccio, et al.. (2010). Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues. Biochemical Pharmacology. 79(10). 1526–1533. 3 indexed citations

12.

Cox, Christopher D., Michael J. Breslin, David B. Whitman, et al.. (2007). Kinesin spindle protein (KSP) inhibitors. Part V: Discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by β-fluorination to overcome cellular efflux by P-glycoprotein. Bioorganic & Medicinal Chemistry Letters. 17(10). 2697–2702. 39 indexed citations

13.

Rickert, Keith, Michael D. Schaber, Maricel Torrent, et al.. (2007). Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP. Archives of Biochemistry and Biophysics. 469(2). 220–231. 40 indexed citations

14.

Yamamoto, Kana, R. M. Garbaccio, Shawn J. Stachel, et al.. (2003). Total Synthesis as a Resource in the Discovery of Potentially Valuable Antitumor Agents: Cycloproparadicicol. Angewandte Chemie. 115(11). 1318–1322. 12 indexed citations

15.

Garbaccio, R. M., et al.. (2003). Thermodynamic equilibration of dihydropyridone enolates: application to the total synthesis of (+/−)-epiuleine. Tetrahedron Letters. 44(51). 9185–9188. 17 indexed citations

16.

Garbaccio, R. M. & Samuel J. Danishefsky. (2000). Efficient Asymmetric Synthesis of Radicicol Dimethyl Ether: A Novel Application of Ring-Forming Olefin Metathesis. Organic Letters. 2(20). 3127–3129. 35 indexed citations

17.

Boger, Dale L. & R. M. Garbaccio. (1999). A Novel Class of CC-1065 and Duocarmycin Analogues Subject to Mitomycin-Related Reductive Activation. The Journal of Organic Chemistry. 64(22). 8350–8362. 28 indexed citations

18.

Boger, Dale L. & R. M. Garbaccio. (1997). Catalysis of the CC-1065 and duocarmycin DNA alkylation reaction: DNA binding induced conformational change in the agent results in activation. Bioorganic & Medicinal Chemistry. 5(2). 263–276. 82 indexed citations

19.

Boger, Dale L., Donald L. Hertzog, Douglas S. Johnson, et al.. (1997). Reversed and Sandwiched Analogs of Duocarmycin SA: Establishment of the Origin of the Sequence-Selective Alkylation of DNA and New Insights into the Source of Catalysis. Journal of the American Chemical Society. 119(21). 4987–4998. 61 indexed citations

20.

Panek, James S., R. M. Garbaccio, & Nareshkumar Jain. (1994). Diastereoselectivity in cyclopropanation and epoxidation reactions of chiral (E)-crotylsilanes: Asymmetric synthesis of substituted tetrahydrofurans. Tetrahedron Letters. 35(35). 6453–6456. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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