R. M. Garbaccio

3.3k citations

40 papers · 1.9k indexed · 1 hit paper · h-index 22

Co-authors: Dale L. Boger Emma R. Parmee Christopher W. Boyce Joel Goldberg Samuel J. Danishefsky Paul J. Coleman Spencer D. Dreher Richard D. Tillyer
Topics: Synthetic Organic Chemistry Methods (9 papers)Chemical Synthesis and Analysis (7 papers)Asymmetric Synthesis and Catalysis (7 papers)
Cited by: Organic Chemistry Toxicology Molecular Biology
Journals: Science Chemical Reviews Journal of the American Chemical Society
Partner nations: United States Italy United Kingdom

In The Last Decade

R. M. Garbaccio

40 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The importance of synthetic chemistry in the pharmaceutical industry

2019 454 citations Kevin R. Campos, Paul J. Coleman et al. Science profile →

Peers

Countries citing papers authored by R. M. Garbaccio

Since Specialization

Citations

This map shows the geographic impact of R. M. Garbaccio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. M. Garbaccio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. M. Garbaccio more than expected).

Fields of papers citing papers by R. M. Garbaccio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. M. Garbaccio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. M. Garbaccio. The network helps show where R. M. Garbaccio may publish in the future.

Co-authorship network of co-authors of R. M. Garbaccio

This figure shows the co-authorship network connecting the top 25 collaborators of R. M. Garbaccio. A scholar is included among the top collaborators of R. M. Garbaccio based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. M. Garbaccio. R. M. Garbaccio is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The importance of synthetic chemistry in the pharmaceutical industrybreakdown → 2019 ·Science ·Kevin R. Campos,Paul J. Coleman,Juan C. Alvarez,Spencer D. Dreher,R. M. Garbaccio,N.K. Terrett,Richard D. Tillyer,Matthew D. Truppo,Emma R. Parmee	454
2	Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations 2019 ·The Journal of Organic Chemistry ·Zachary Z. Brown,Claudio Mapelli,Iman Farasat,(unknown),S.A. Johnson,Federica Orvieto,Alessia Santoprete,Elisabetta Bianchi,(unknown),(unknown),Xiaohong Zhu,Mark J. Demma,Brian M. Lacey,Keith A. Canada,R. M. Garbaccio,Jennifer O’Neil,Abbas M. Walji	19
3	The Impact of Chemical Probes in Drug Discovery: A Pharmaceutical Industry Perspective 2016 ·Cell chemical biology ·R. M. Garbaccio,Emma R. Parmee	57
4	An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents 2014 ·International Journal of Pharmaceutics ·Stephanie E. Barrett,Marc Abrams,Rob S. Burke,Brian Carr,Louis S. Crocker,R. M. Garbaccio,Bonnie J. Howell,(unknown),(unknown),Andrew H. Latham,Karen Leander,Anthony Leone,Mihir Patel,Sergei Pechenov,Nicole T. Pudvah,(unknown),Laura Sepp‐Lorenzino,Eileen S. Walsh,Jonathan Williams,Steven L. Colletti	13
5	Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase 2014 ·Bioorganic & Medicinal Chemistry Letters ·Antonella Converso,(unknown),Mark E. Fraley,R. M. Garbaccio,George D. Hartman,(unknown),John Majercak,Alexander McCampbell,(unknown),William J. Ray,Mary J. Savage,(unknown),Suzie Yeh,(unknown),Rebecca B. White,Rena Zhang	12
6	Improving the In Vivo Therapeutic Index of siRNA Polymer Conjugates through Increasing pH Responsiveness 2014 ·Bioconjugate Chemistry ·Erin N. Guidry,(unknown),Arash Soheili,Craig A. Parish,(unknown),Brenda Pipik,(unknown),N. Ikemoto,Jacob H. Waldman,Andrew H. Latham,Bonnie J. Howell,Anthony Leone,R. M. Garbaccio,Stephanie E. Barrett,Rubina Parmar,Quang Tri Truong,Bing Mao,Ian W. Davies,Steven L. Colletti,Laura Sepp‐Lorenzino	15
7	Endosomolytic Bioreducible Poly(amido amine disulfide) Polymer Conjugates for the in Vivo Systemic Delivery of siRNA Therapeutics 2013 ·Bioconjugate Chemistry ·Rubina Parmar,(unknown),Eileen S. Walsh,Karen Leander,Bonnie J. Howell,Laura Sepp‐Lorenzino,(unknown),Louis S. Crocker,Anthony Leone,Christopher J. Kochansky,Brian Carr,R. M. Garbaccio,Steven L. Colletti,Weimin Wang	33
8	Discovery of Allosteric Inhibitors of Kinesin Spindle Protein (KSP) for the Treatment of Taxane-Refractory Cancer: MK-0731 and Analogs 2010 ·Anti-Cancer Agents in Medicinal Chemistry ·Christopher D. Cox,R. M. Garbaccio	11
9	3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts 2010 ·Bioorganic & Medicinal Chemistry Letters ·Edward J. Brnardic,Mark E. Fraley,R. M. Garbaccio,M. E. Layton,John M. Sanders,Chris Culberson,Marlene A. Jacobson,Brian C. Magliaro,Pete H. Hutson,Julie A. O’Brien,Sarah L. Huszar,Jason M. Uslaner,Kerry L. Fillgrove,Cuyue Tang,Yuhsin Kuo,(unknown),George D. Hartman	30
10	Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues 2010 ·Biochemical Pharmacology ·Chunze Li,Bing Lu,R. M. Garbaccio,(unknown),Mark E. Fraley,George D. Hartman,Jingjing Ye,(unknown),Thomayant Prueksaritanont	3
11	Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor 2010 ·ACS Medicinal Chemistry Letters ·R. M. Garbaccio,Edward J. Brnardic,Mark E. Fraley,George D. Hartman,Pete H. Hutson,Julie A. O’Brien,Brian C. Magliaro,Jason M. Uslaner,Sarah L. Huszar,Kerry L. Fillgrove,James H. Small,Cuyue Tang,Yuhsin Kuo,Marlene A. Jacobson	14
12	ChemInform Abstract: 2‐Aminoalkanoic Acids (α‐Amino Acids) 2008 ·ChemInform ·S. E. Wolkenberg,R. M. Garbaccio	1
13	Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP 2007 ·Archives of Biochemistry and Biophysics ·Keith Rickert,Michael D. Schaber,Maricel Torrent,(unknown),(unknown),R. M. Garbaccio,Paul J. Coleman,(unknown),Yun Zhang,Yi Yang,Gary T. Marshall,Ling Lee,Eileen S. Walsh,Kelly Hamilton,Carolyn A. Buser	40
14	Kinesin spindle protein (KSP) inhibitors. Part V: Discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by β-fluorination to overcome cellular efflux by P-glycoprotein 2007 ·Bioorganic & Medicinal Chemistry Letters ·Christopher D. Cox,Michael J. Breslin,David B. Whitman,Paul J. Coleman,R. M. Garbaccio,Mark E. Fraley,Matthew M. Zrada,Carolyn A. Buser,Eileen S. Walsh,Kelly Hamilton,Robert B. Lobell,Weikang Tao,Marc Abrams,Vicki J. South,Hans E. Huber,Nancy E. Kohl,George D. Hartman	39
15	Total Synthesis as a Resource in the Discovery of Potentially Valuable Antitumor Agents: Cycloproparadicicol 2003 ·Angewandte Chemie ·Kana Yamamoto,R. M. Garbaccio,Shawn J. Stachel,David B. Solit,Gabriela Chiosis,Neal Rosen,Samuel J. Danishefsky	12
16	Total Synthesis as a Resource in the Discovery of Potentially Valuable Antitumor Agents: Cycloproparadicicol 2003 ·Angewandte Chemie International Edition ·Kana Yamamoto,R. M. Garbaccio,Shawn J. Stachel,David B. Solit,Gabriela Chiosis,Neal Rosen,Samuel J. Danishefsky	58
17	ChemInform Abstract: Synthesis and Evaluation of a Series of C3‐Substituted CBI Analogues of CC‐1065 and the Duocarmycins. 2001 ·ChemInform ·Dale L. Boger,S.R. Brunette,R. M. Garbaccio	2
18	Catalysis of the CC-1065 and duocarmycin DNA alkylation reaction: DNA binding induced conformational change in the agent results in activation 1997 ·Bioorganic & Medicinal Chemistry ·Dale L. Boger,R. M. Garbaccio	82
19	Reversed and Sandwiched Analogs of Duocarmycin SA: Establishment of the Origin of the Sequence-Selective Alkylation of DNA and New Insights into the Source of Catalysis 1997 ·Journal of the American Chemical Society ·Dale L. Boger,(unknown),Donald L. Hertzog,Douglas S. Johnson,Hui Cai,Philippe J. Mésini,R. M. Garbaccio,Qing Jin,Paul A. Kitos	61
20	Diastereoselectivity in cyclopropanation and epoxidation reactions of chiral (E)-crotylsilanes: Asymmetric synthesis of substituted tetrahydrofurans 1994 ·Tetrahedron Letters ·James S. Panek,R. M. Garbaccio,Nareshkumar Jain	24

About R. M. Garbaccio

R. M. Garbaccio is a scholar working on Toxicology, Organic Chemistry and Pharmacology, having authored 40 papers that have together received 1.9k indexed citations. Recurring topics across this work include Synthetic Organic Chemistry Methods (9 papers), Chemical Synthesis and Analysis (7 papers) and Asymmetric Synthesis and Catalysis (7 papers). The work is most often cited by research in Organic Chemistry (1.2k citations), Toxicology (109 citations) and Molecular Biology (959 citations). R. M. Garbaccio has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Dale L. Boger, Emma R. Parmee, Christopher W. Boyce, Joel Goldberg, Samuel J. Danishefsky, Paul J. Coleman, Spencer D. Dreher, Richard D. Tillyer, Kevin R. Campos and N.K. Terrett. Their work appears in journals such as Science, Chemical Reviews and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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