Bruce E. Clurman

14.0k citations

77 papers · 9.6k indexed · 4 hit papers · h-index 45

Impact in

Oncology top 0.5%
- Cancer-related Molecular Pathways
Molecular Biology top 0.5%
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Protein Degradation and Inhibitors
- DNA Repair Mechanisms
- Cancer-related gene regulation

Papers in

Oncology 40
- Cancer-related Molecular Pathways 34
- Peptidase Inhibition and Analysis 8
Molecular Biology 68
- Ubiquitin and proteasome pathways 31
- Epigenetics and DNA Methylation 14
- RNA modifications and cancer 12
- Genomics and Chromatin Dynamics 7

Co-authors: Markus Welcker Robert J. Sheaff Harry C. Hwang Jonathan Grim Mark Groudine Joanna Roberts James M. Roberts Jherek Swanger
Journals: Molecular and Cellular Biology (10 papers)Genes & Development (8 papers)Proceedings of the National Academy of Sciences (7 papers)Molecular Cell (6 papers)Current Biology (4 papers)
Partner nations: United States South Africa United Kingdom

In The Last Decade

Bruce E. Clurman

76 papers receiving 9.5k citations

Hit Papers

align trajectories log scale

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors 2007 · 523 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 The Journal of Experimental Medicine
2007 Nature reviews. Cancer
2004 Proceedings of the National Academy of Sciences
1997 Genes & Development

Peers

Countries citing papers authored by Bruce E. Clurman

Since Specialization

Citations

This map shows the geographic impact of Bruce E. Clurman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce E. Clurman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce E. Clurman more than expected).

Fields of papers citing papers by Bruce E. Clurman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce E. Clurman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce E. Clurman. The network helps show where Bruce E. Clurman may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Bruce E. Clurman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruce E. Clurman Line = papers co-authored together Bruce E. Clurman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor Science Advances ·Markus Welcker, Baiyun Wang, Domnița-Valeria Rusnac, E.I. Novosyolova, Jherek Swanger, Ning Zheng, Bruce E. Clurman	2022	34
2	Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12 Nature Communications ·Omar M. Khan, Jorge Almagro, Jessica K. Nelson, Stuart Horswell, Vesela Encheva, Bryan Kennedy, Bruce E. Clurman, Ambrosius P. Snijders, Axel Behrens	2021	23
3	DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing Cell Reports ·Philamer Calses, Kiranjit K. Dhillon, N. S. Grishina, Yong Chi, Jen‐Wei Huang, Masaoki Kawasumi, Paul Nghiem, Yemin Wang, Bruce E. Clurman, Céline Jacquemont, Philip R. Gafken, Kaoru Sugasawa, Masafumi Saijo, Toshiyasu Taniguchi	2017	28
4	Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities Cancer Cell ·Ryan J. Davis, Markus Welcker, Bruce E. Clurman	2014	275
5	Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins Cell ·Nathan W. Pierce, J. Eugene Lee, Xing Liu, Michael J. Sweredoski, R. L. Graham, Parisa Pahlavani, Michael E. Rome, Ning Zheng, Bruce E. Clurman, Sonja Hess, Shu‐ou Shan, Raymond J. Deshaies	2013	205
6	Fbw7 Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions PLoS Biology ·Rocı́o Sancho, Sophia M. Blake, Christian Tendeng, Bruce E. Clurman, Julian Lewis, Axel Behrens	2013	50
7	A Mechanism Misregulating p27 in Tumors Discovered in a Functional Genomic Screen PLoS Genetics ·Carrie M. Garrett-Engele, Michael Tasch, Harry C. Hwang, Matthew L. Fero, Roger M. Perlmutter, Bruce E. Clurman, James M. Roberts	2007	18
8	Ubiquitin-Independent Degradation of Cell-Cycle Inhibitors by the REGγ Proteasome Molecular Cell ·Xueyan Chen, Lance F. Barton, Yong Chi, Bruce E. Clurman, James M. Roberts	2007	230
9	Kinase-Independent Function of Cyclin E Molecular Cell ·Yan Geng, Young Mi Lee, Markus Welcker, Jherek Swanger, Agnieszka Zagożdżon, María Victoria Morales-Morales, James M. Roberts, Philipp Kaldis, Bruce E. Clurman, Piotr Siciński	2007	138
10	Fbw7/hCDC4 dimerization regulates its substrate interactions. Cell Division ·Markus Welcker, Bruce E. Clurman	2007	104
11	A Nucleolar Isoform of the Fbw7 Ubiquitin Ligase Regulates c-Myc and Cell Size Current Biology ·Markus Welcker, Amir Orian, Jonathan E. Grim, Robert N. Eisenman, Bruce E. Clurman	2005	12
12	Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins Biochemical and Biophysical Research Communications ·Michael P. Gustafson, Markus Welcker, Harry C. Hwang, Bruce E. Clurman	2005	22
13	Cell Cycle: How Cyclin E Got Its Groove Back Current Biology ·Markus Welcker, Bruce E. Clurman	2005	9
14	Cyclin E in normal and neoplastic cell cycles Oncogene ·Harry C. Hwang, Bruce E. Clurman	2005	376
15	The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation Proceedings of the National Academy of Sciences ·Markus Welcker, Amir Orian, Jianping Jin, Jonathan Grim, J. Wade Harper, Robert N. Eisenman, Bruce E. Clurman Hit paper breakdown →	2004	756
16	The SV40 Large T Antigen Contains a Decoy Phosphodegron That Mediates Its Interactions with Fbw7/hCdc4 Journal of Biological Chemistry ·Markus Welcker, Bruce E. Clurman	2004	62
17	Werner syndrome protein limits MYC-induced cellular senescence Genes & Development ·Carla Grandori, Kou-Juey Wu, Paula Fernández, Celine Ngouenet, Jonathan Grim, Bruce E. Clurman, Michael J. Moser, Junko Oshima, David W. Russell, Karen Swisshelm, Scott R. Frank, Bruno Amati, Riccardo Dalla‐Favera, Raymond J. Monnat	2003	146
18	Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation Molecular Cell ·Markus Welcker, Jeffrey D. Singer, Keith R. Loeb, Jonathan Grim, Andrew Bloecher, Ouafa Louafi, Bruce E. Clurman, James M. Roberts	2003	302
19	Npap60/Nup50 Is a Tri-Stable Switch that Stimulates Importin-α:β-Mediated Nuclear Protein Import Cell ·Mark E. Lindsay, Kendra S. Plafker, Alicia E. Smith, Bruce E. Clurman, Ian G. Macara	2002	98
20	p53 and p21 Form an Inducible Barrier that Protects Cells against Cyclin E-cdk2 Deregulation Current Biology ·Alex C. Minella, Jherek Swanger, Eileen Bryant, Markus Welcker, Harry C. Hwang, Bruce E. Clurman	2002	98

About Bruce E. Clurman

Bruce E. Clurman is a scholar working on Oncology, Molecular Biology, Cell Biology, Hematology and Genetics, having authored 77 papers that have together received 9.6k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (34 papers), Ubiquitin and proteasome pathways (31 papers), Epigenetics and DNA Methylation (14 papers), Microtubule and mitosis dynamics (12 papers), RNA modifications and cancer (12 papers), Peptidase Inhibition and Analysis (8 papers), Genomics and Chromatin Dynamics (7 papers) and Genetics and Neurodevelopmental Disorders (7 papers). The work is most often cited by research in Oncology (4.2k citations), Molecular Biology (7.8k citations), Cell Biology (1.9k citations), Cancer Research (1.2k citations) and Hematology (547 citations). Bruce E. Clurman has collaborated with scholars based in United States, South Africa and United Kingdom. Frequent co-authors include Markus Welcker, Robert J. Sheaff, Harry C. Hwang, Jonathan Grim, Mark Groudine, Joanna Roberts, James M. Roberts, Jherek Swanger, James M. Roberts and Robert N. Eisenman. Their work appears in journals such as Molecular and Cellular Biology, Genes & Development, Proceedings of the National Academy of Sciences, Molecular Cell and Current Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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