Caroline E. Shamu

6.5k total citations · 3 hit papers
22 papers, 4.4k citations indexed

About

Caroline E. Shamu is a scholar working on Molecular Biology, Cell Biology and Epidemiology. According to data from OpenAlex, Caroline E. Shamu has authored 22 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 7 papers in Cell Biology and 3 papers in Epidemiology. Recurrent topics in Caroline E. Shamu's work include Endoplasmic Reticulum Stress and Disease (6 papers), RNA and protein synthesis mechanisms (5 papers) and Molecular Biology Techniques and Applications (4 papers). Caroline E. Shamu is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (6 papers), RNA and protein synthesis mechanisms (5 papers) and Molecular Biology Techniques and Applications (4 papers). Caroline E. Shamu collaborates with scholars based in United States, United Kingdom and Hong Kong. Caroline E. Shamu's co-authors include Peter Walter, Jeffery S. Cox, Peter Walter, Michael M. Shen, Jonathan Hodgkin, Christopher S. Raymond, David Zarkower, Betsy Hirsch, Hidde L. Ploegh and Tom A. Rapoport and has published in prestigious journals such as Nature, Cell and Nature Reviews Molecular Cell Biology.

In The Last Decade

Caroline E. Shamu

22 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus.

1996 1.1k citations Caroline E. Shamu, Peter Walter profile →
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1993 989 citations Jeffery S. Cox, Caroline E. Shamu et al. Cell profile →
Evidence for evolutionary conservation of sex-determining genes

1998 619 citations Christopher S. Raymond, Caroline E. Shamu et al. Nature profile →

Peers

Countries citing papers authored by Caroline E. Shamu

Since Specialization

Citations

This map shows the geographic impact of Caroline E. Shamu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Caroline E. Shamu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Caroline E. Shamu more than expected).

Fields of papers citing papers by Caroline E. Shamu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Caroline E. Shamu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Caroline E. Shamu. The network helps show where Caroline E. Shamu may publish in the future.

Co-authorship network of co-authors of Caroline E. Shamu

This figure shows the co-authorship network connecting the top 25 collaborators of Caroline E. Shamu. A scholar is included among the top collaborators of Caroline E. Shamu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Caroline E. Shamu. Caroline E. Shamu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS) 2014 ·SLAS DISCOVERY ·Uma D. Vempati, Caty Chung, (unknown), Amar Koleti, (unknown), D. Vidović, David M. Wrobel, (unknown), Jeremy L. Muhlich, Gabriel F. Berriz, Cyril H. Benes, Aravind Subramanian, Ajay Pillai, Caroline E. Shamu, Stephan C. Schürer	51
2	RNAi screening comes of age: improved techniques and complementary approaches 2014 ·Nature Reviews Molecular Cell Biology ·Stephanie E. Mohr, Jennifer A. Smith, Caroline E. Shamu, Ralph A. Neumüller, Norbert Perrimon	247
3	Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis 2014 ·BMC Bioinformatics ·Bahar Yilmazel, Yanhui Hu, Frederic Sigoillot, Jennifer A. Smith, Caroline E. Shamu, Norbert Perrimon, Stephanie E. Mohr	32
4	On target: A public repository for large-scale RNAi experiments 2012 ·Nature Cell Biology ·Caroline E. Shamu, Stefan Wiemann, Michael Boutros	7
5	Traditional Medicine Collection Tracking System (TM-CTS): A database for ethnobotanically driven drug-discovery programs 2011 ·Journal of Ethnopharmacology ·Eric S. J. Harris, (unknown), Andrew Tolopko, Shugeng Cao, (unknown), (unknown), (unknown), Wenquan Wang, Yong Liu, Zhongzhen Zhao, Jon Clardy, Caroline E. Shamu, David M. Eisenberg	10
6	A High-Throughput, Cell-Based Screening Method for siRNA and Small Molecule Inhibitors of mTORC1 Signaling Using the In Cell Western Technique 2010 ·Assay and Drug Development Technologies ·Gregory R. Hoffman, Nathan J. Moerke, (unknown), Caroline E. Shamu, John Blenis	30
7	Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities 2010 ·BMC Bioinformatics ·Andrew Tolopko, John P. Sullivan, (unknown), David M. Wrobel, Su L. Chiang, (unknown), (unknown), (unknown), Laura M. Selfors, (unknown), Jeremy L. Muhlich, Caroline E. Shamu	23
8	Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation — Rationale, methods and preliminary results from a Sino-American collaboration 2010 ·Fitoterapia ·David M. Eisenberg, Eric S. J. Harris, Bruce A. Littlefield, Shugeng Cao, (unknown), (unknown), (unknown), (unknown), Wenquan Wang, (unknown), Zhongzhen Zhao, Hubiao Chen, Yong Liu, Ted J. Kaptchuk, William C. Hahn, Xiaoxing Wang, Thomas M. Roberts, Caroline E. Shamu, Jon Clardy	37
9	Statistical methods for analysis of high-throughput RNA interference screens 2009 ·Nature Methods ·Amanda Birmingham, Laura M. Selfors, Thorsten Forster, David M. Wrobel, Caleb J. Kennedy, Emma Shanks, Javier Santoyo‐López, Dara J. Dunican, Aideen Long, Dermot Kelleher, (unknown), Roderick L. Beijersbergen, Peter Ghazal, Caroline E. Shamu	439
10	An Intermittent Live Cell Imaging Screen for siRNA Enhancers and Suppressors of a Kinesin-5 Inhibitor 2009 ·PLoS ONE ·(unknown), Tiao Xie, James D. Orth, Anne E. Carpenter, (unknown), (unknown), Caroline E. Shamu, Timothy J. Mitchison	21
11	Reporting data from high-throughput screening of small-molecule libraries 2007 ·Nature Chemical Biology ·James Inglese, Caroline E. Shamu, R. Kiplin Guy	79
12	Polyubiquitination Is Required for US11-dependent Movement of MHC Class I Heavy Chain from Endoplasmic Reticulum into Cytosol 2001 ·Molecular Biology of the Cell ·Caroline E. Shamu, Dennis Flierman, Hidde L. Ploegh, Tom A. Rapoport, Vincent Chau	111
13	Degradation of Proteins from the ER of S. cerevisiae Requires an Intact Unfolded Protein Response Pathway 2000 ·Molecular Cell ·Rocco Casagrande, Patrick Stern, Maximilian Diehn, Caroline E. Shamu, (unknown), (unknown), Patrick O. Brown, Hidde L. Ploegh	154
14	The Pathway of Us11-Dependent Degradation of Mhc Class I Heavy Chains Involves a Ubiquitin-Conjugated Intermediate 1999 ·The Journal of Cell Biology ·Caroline E. Shamu, Craig M. Story, Tom A. Rapoport, Hidde L. Ploegh	133
15	Splicing: HACking into the unfolded-protein response 1998 ·Current Biology ·Caroline E. Shamu	26
16	Evidence for evolutionary conservation of sex-determining genes breakdown → 1998 ·Nature ·Christopher S. Raymond, Caroline E. Shamu, Michael M. Shen, (unknown), Betsy Hirsch, Jonathan Hodgkin, David Zarkower	619
17	Signal transduction: Splicing together the unfolded-protein response 1997 ·Current Biology ·Caroline E. Shamu	31
18	The unfolded-protein-response pathway in yeast 1994 ·Trends in Cell Biology ·Caroline E. Shamu, Jeffery S. Cox, Peter Walter	130
19	Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase breakdown → 1993 ·Cell ·Jeffery S. Cox, Caroline E. Shamu, Peter Walter	989
20	C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons 1992 ·Nature ·David M. Miller, Michael M. Shen, Caroline E. Shamu, Thomas R. Bürglin, Gary Ruvkun, (unknown), (unknown), Laura C. Wilson	156

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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