Peter Walter

65.8k total citations · 25 hit papers
354 papers, 50.4k citations indexed

About

Peter Walter is a scholar working on Molecular Biology, Cell Biology and Genetics. According to data from OpenAlex, Peter Walter has authored 354 papers receiving a total of 50.4k indexed citations (citations by other indexed papers that have themselves been cited), including 251 papers in Molecular Biology, 149 papers in Cell Biology and 77 papers in Genetics. Recurrent topics in Peter Walter's work include Endoplasmic Reticulum Stress and Disease (114 papers), RNA and protein synthesis mechanisms (98 papers) and Bacterial Genetics and Biotechnology (67 papers). Peter Walter is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (114 papers), RNA and protein synthesis mechanisms (98 papers) and Bacterial Genetics and Biotechnology (67 papers). Peter Walter collaborates with scholars based in United States, Germany and Canada. Peter Walter's co-authors include David Ron, Günter Blobel, Carmela Sidrauski, Sebastián Bernales, Caroline E. Shamu, Jonathan H. Lin, Mauro Costa‐Mattioli, Reid Gilmore, Jodi Nunnari and Brooke M. Gardner and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Peter Walter

347 papers receiving 49.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Signal integration in the endoplasmic reticulum unfolded protein response

2007 5.2k citations David Ron, Peter Walter Nature Reviews Molecular Cell Biology profile →
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

2011 4.5k citations Peter Walter, David Ron Science profile →
IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response

2007 1.1k citations Jonathan H. Lin, Han Li et al. Science profile →
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus.

1996 1.1k citations Peter Walter et al. profile →
An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

2009 1.0k citations Benoı̂t Kornmann, Erin Currie et al. Science profile →
The integrated stress response: From mechanism to disease

2020 892 citations Mauro Costa‐Mattioli, Peter Walter Science profile →
Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response

2006 802 citations Peter Walter et al. profile →
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

2009 775 citations Jonathan H. Lin, Han Li et al. The Journal of Cell Biology profile →
Protein translocation across the endoplasmic reticulum

1984 705 citations Peter Walter et al. profile →
The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response

1997 692 citations Carmela Sidrauski, Peter Walter profile →
Endoplasmic Reticulum Stress in Disease Pathogenesis

2008 660 citations Jonathan H. Lin, Peter Walter et al. profile →
Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

1981 638 citations Peter Walter et al. The Journal of Cell Biology profile →
[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 615 citations Peter Walter et al. profile →
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

2008 614 citations Tobias C. Walther, Peter Walter et al. profile →
Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum

1982 604 citations Peter Walter et al. profile →
Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

2013 587 citations Peter Walter et al. profile →
Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

2009 578 citations Sean R. Collins, Peter Walter et al. Science profile →
Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

2011 544 citations Peter Walter et al. Science profile →
Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein.

1981 527 citations Peter Walter et al. The Journal of Cell Biology profile →
The unfolded protein response signals through high-order assembly of Ire1

2008 512 citations Alexei Korennykh, Janet Finer-Moore et al. profile →
Pharmacological brake-release of mRNA translation enhances cognitive memory

2013 500 citations Carmela Sidrauski, Diego Acosta‐Alvear et al. eLife profile →
The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

2015 456 citations Carmela Sidrauski, Peter Walter et al. eLife profile →
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

2014 447 citations Min Lu, David A. Lawrence et al. Science profile →
Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein.

1981 341 citations Peter Walter et al. The Journal of Cell Biology profile →
Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle.

1982 310 citations Peter Walter et al. The Journal of Cell Biology profile →

Peers

Countries citing papers authored by Peter Walter

Since Specialization

Citations

This map shows the geographic impact of Peter Walter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter Walter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter Walter more than expected).

Fields of papers citing papers by Peter Walter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter Walter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter Walter. The network helps show where Peter Walter may publish in the future.

Co-authorship network of co-authors of Peter Walter

This figure shows the co-authorship network connecting the top 25 collaborators of Peter Walter. A scholar is included among the top collaborators of Peter Walter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Peter Walter. Peter Walter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling 2023 ·Nature Chemical Biology ·Rosalie Lawrence, Sophie R. Shoemaker, (unknown), Smriti Sangwan, Aditya Anand, Lan Wang, Susan Marqusee, Peter Walter	1
2	A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response 2023 ·Nature Cell Biology ·Advait Subramanian, Lan Wang, Tom Moss, Mark Voorhies, Smriti Sangwan, Erica Stevenson, Ernst H. Pulido, (unknown), Robert J. Chalkley, Kathy H. Li, Nevan J. Krogan, Danielle L. Swaney, Alma L. Burlingame, Stephen N. Floor, Anita Sil, Peter Walter, Shaeri Mukherjee	11
3	Intercepting IRE1 kinase‐FMRP signaling prevents atherosclerosis progression 2022 ·EMBO Molecular Medicine ·(unknown), Sabyasachi Baboo, Syed Muhammad Hamid, (unknown), Özlem Tufanlı, Sabrina Robichaud, (unknown), Jolene K. Diedrich, Hasan Vatandaslar, Fotis Nikolos, Yanghong Gu, Takao Iwawaki, Elizabeth J. Tarling, Mireille Ouimet, David L. Nelson, John R. Yates, Peter Walter, Ebru Erbay	26
4	The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 2018 ·eLife ·Diego Acosta‐Alvear, G Elif Karagöz, Florian Fröhlich, Li Han, Tobias C. Walther, Peter Walter	71
5	Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury 2017 ·Proceedings of the National Academy of Sciences ·Austin Chou, Karen Krukowski, Timothy Jopson, Ping Zhu, Mauro Costa‐Mattioli, Peter Walter, Susanna Rosi	175
6	Translation from the 5′ untranslated region shapes the integrated stress response 2016 ·Science ·Shelley R. Starck, Jordan C. Tsai, Keling Chen, (unknown), Lei Wang, Kinnosuke Yahiro, Manuela Martins‐Green, Nilabh Shastri, Peter Walter	275
7	Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer 2015 ·Molecular Cancer Therapeutics ·Xiaokai Li, Teresa A. Colvin, Jennifer N. Rauch, Diego Acosta‐Alvear, Martin Kampmann, Bryan M. Dunyak, Byron Hann, Blake T. Aftab, Megan Murnane, Min Cho, Peter Walter, Jonathan S. Weissman, Michael Y. Sherman, Jason E. Gestwicki	101
8	The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins 2014 ·Proceedings of the National Academy of Sciences ·Voytek Okreglak, Peter Walter	170
9	Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis breakdown → 2014 ·Science ·Min Lu, David A. Lawrence, Scot A. Marsters, Diego Acosta‐Alvear, Philipp Kimmig, Aaron S. Mendez, Adrienne W. Paton, James C. Paton, Peter Walter, Avi Ashkenazi	447
10	Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α 2014 ·Nature Neuroscience ·Gonzalo Viana Di Prisco, Wei‐Chien Huang, Shelly A. Buffington, (unknown), Penelope E. Bonnen, Andon N. Placzek, Carmela Sidrauski, K. Krnjević, Randal J. Kaufman, Peter Walter, Mauro Costa‐Mattioli	153
11	Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity 2011 ·The Journal of Cell Biology ·(unknown), David Pincus, Alexei Korennykh, Sebastian Schuck, Hana El‐Samad, Peter Walter	124
12	An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen breakdown → 2009 ·Science ·Benoı̂t Kornmann, Erin Currie, Sean R. Collins, Maya Schuldiner, Jodi Nunnari, Jonathan S. Weissman, Peter Walter	1013
13	Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response 2009 ·The Journal of Cell Biology ·Sebastian Schuck, William A. Prinz, Kurt S. Thorn, Christiane Voss, Peter Walter	438
14	The Signal Recognition Particle (SRP) RNA Links Conformational Changes in the SRP to Protein Targeting 2007 ·Molecular Biology of the Cell ·Niels Bradshaw, Peter Walter	30
15	IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response breakdown → 2007 ·Science ·Jonathan H. Lin, Han Li, Douglas Yasumura, Hannah Cohen, Chao Zhang, Barbara Panning, Kevan M. Shokat, Matthew M. LaVail, Peter Walter	1140
16	The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating 2007 ·The Journal of Cell Biology ·Maxwell G. Heiman, Alex Engel, Peter Walter	32
17	Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation 2007 ·The Journal of Cell Biology ·Shu‐ou Shan, Sowmya Chandrasekar, Peter Walter	62
18	Signal integration in the endoplasmic reticulum unfolded protein response breakdown → 2007 ·Nature Reviews Molecular Cell Biology ·David Ron, Peter Walter	5163
19	On the mechanism of sensing unfolded protein in the endoplasmic reticulum 2005 ·Proceedings of the National Academy of Sciences ·Joel J. Credle, Janet Finer-Moore, Feroz R. Papa, R. M. Stroud, Peter Walter	423
20	Bypassing a Kinase Activity with an ATP-Competitive Drug 2003 ·Science ·Feroz R. Papa, Chao Zhang, Kevan M. Shokat, Peter Walter	195

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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