William C. Hahn

101.6k total citations · 23 hit papers
293 papers, 40.9k citations indexed

About

William C. Hahn is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, William C. Hahn has authored 293 papers receiving a total of 40.9k indexed citations (citations by other indexed papers that have themselves been cited), including 183 papers in Molecular Biology, 73 papers in Oncology and 63 papers in Cancer Research. Recurrent topics in William C. Hahn's work include Telomeres, Telomerase, and Senescence (45 papers), Cancer Genomics and Diagnostics (39 papers) and Cancer-related Molecular Pathways (27 papers). William C. Hahn is often cited by papers focused on Telomeres, Telomerase, and Senescence (45 papers), Cancer Genomics and Diagnostics (39 papers) and Cancer-related Molecular Pathways (27 papers). William C. Hahn collaborates with scholars based in United States, Germany and Japan. William C. Hahn's co-authors include Robert A. Weinberg, Mary W. Brooks, Roderick L. Beijersbergen, Matthew Meyerson, Christopher M. Counter, Ante S. Lundberg, Sheila A. Stewart, Brent R. Stockwell, David E. Root and Sonam Dolma and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

William C. Hahn

285 papers receiving 40.2k citations

Hit Papers

Creation of human tumour cells with defined genetic elements 1998 2026 2007 2016 1999 2007 2006 2003 2003 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Creation of human tumour cells with defined genetic elements
    1999 1.8k citations William C. Hahn et al. profile →
  2. Malignant astrocytic glioma: genetics, biology, and paths to treatment
    2007 1.8k citations William C. Hahn et al. profile →
  3. A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen
    2006 1.4k citations Anne E. Carpenter, William C. Hahn et al. profile →
  4. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
    2003 1.2k citations William C. Hahn et al. profile →
  5. Lentivirus-delivered stable gene silencing by RNAi in primary cells
    2003 1.1k citations William C. Hahn, Carl D. Novina et al. profile →
  6. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9
    2006 1.0k citations William C. Hahn, Todd R. Golub et al. profile →
  7. Human Keratinocytes That Express hTERT and Also Bypass a p16INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics
    2000 874 citations William C. Hahn et al. profile →
  8. Inhibition of telomerase limits the growth of human cancer cells
    1999 862 citations William C. Hahn, Matthew Meyerson et al. profile →
  9. Recurrent BRAF mutations in Langerhans cell histiocytosis
    2010 742 citations Gayane Badalian‐Very, Jo‐Anne Vergilio et al. Blood profile →
  10. Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
    2011 732 citations Nikhil Wagle, Michael F. Berger et al. Journal of Clinical Oncology profile →
  11. Rules for Making Human Tumor Cells
    2002 685 citations William C. Hahn et al. profile →
  12. Modelling the molecular circuitry of cancer
    2002 681 citations William C. Hahn et al. profile →
  13. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    2001 677 citations Mark D. Fleming, William C. Hahn et al. profile →
  14. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
    2004 619 citations William C. Hahn et al. profile →
  15. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
    2014 573 citations Federica Piccioni, Anna C. Schinzel et al. profile →
  16. Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants
    2005 536 citations William C. Hahn, William R. Sellers et al. profile →
  17. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
    1998 533 citations William C. Hahn et al. Proceedings of the National Academy of Sciences profile →
  18. Emerging insights into the molecular and cellular basis of glioblastoma
    2012 425 citations Gavin P. Dunn, William C. Hahn et al. profile →
  19. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
    2013 419 citations Gad Getz, Paul Van Hummelen et al. Nature Genetics profile →
  20. A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors
    2014 357 citations David J. Konieczkowski, Cory M. Johannessen et al. Cancer Discovery profile →
  21. Chemosensitivity linked to p73 function
    2003 345 citations William C. Hahn et al. profile →
  22. Biologically informed deep neural network for prostate cancer discovery
    2021 239 citations William C. Hahn et al. profile →
  23. Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects
    2021 204 citations Francisca Vázquez, David E. Root et al. Genome biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
William C. Hahn United States 101 26.5k 11.2k 7.8k 5.8k 4.9k 293 40.9k
Lynda Chin United States 82 20.4k 0.8× 9.3k 0.8× 6.7k 0.9× 3.9k 0.7× 2.2k 0.5× 160 29.4k
Hiroyuki Aburatani Japan 98 24.4k 0.9× 8.4k 0.7× 7.6k 1.0× 2.0k 0.3× 6.1k 1.2× 531 38.1k
Amato J. Giaccia United States 103 23.1k 0.9× 10.8k 1.0× 17.4k 2.2× 2.6k 0.4× 4.2k 0.8× 350 40.3k
Amanda G. Paulovich United States 40 26.0k 1.0× 7.0k 0.6× 8.3k 1.1× 2.1k 0.4× 5.6k 1.1× 87 40.1k
René Bernards Netherlands 90 30.7k 1.2× 16.4k 1.5× 9.8k 1.3× 1.7k 0.3× 3.9k 0.8× 322 44.6k
David J. Kwiatkowski United States 101 15.9k 0.6× 7.3k 0.7× 3.9k 0.5× 9.5k 1.6× 7.0k 1.4× 395 33.3k
Scott W. Lowe United States 123 50.1k 1.9× 23.0k 2.0× 16.9k 2.2× 6.6k 1.1× 3.6k 0.7× 325 69.6k
Julian Downward United Kingdom 101 30.1k 1.1× 11.4k 1.0× 4.9k 0.6× 1.6k 0.3× 3.1k 0.6× 292 41.7k
Carlos Cordon‐Cardo United States 129 41.4k 1.6× 22.8k 2.0× 12.8k 1.6× 3.5k 0.6× 11.0k 2.2× 564 68.1k
William G. Kaelin United States 117 35.6k 1.3× 14.8k 1.3× 22.6k 2.9× 3.2k 0.6× 6.0k 1.2× 246 50.2k

Countries citing papers authored by William C. Hahn

Since Specialization
Citations

This map shows the geographic impact of William C. Hahn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Hahn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Hahn more than expected).

Fields of papers citing papers by William C. Hahn

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Hahn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Hahn. The network helps show where William C. Hahn may publish in the future.

Co-authorship network of co-authors of William C. Hahn

This figure shows the co-authorship network connecting the top 25 collaborators of William C. Hahn. A scholar is included among the top collaborators of William C. Hahn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William C. Hahn. William C. Hahn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Way, Gregory P., Maria Kost‐Alimova, Tsukasa Shibue, et al.. (2021). Predicting cell health phenotypes using image-based morphology profiling. Molecular Biology of the Cell. 32(9). 995–1005. 77 indexed citations
2.
Hong, Andrew L., Jennifer L. Guerriero, Mihir B. Doshi, et al.. (2019). MCL1 and DEDD Promote Urothelial Carcinoma Progression. Molecular Cancer Research. 17(6). 1294–1304. 4 indexed citations
3.
Durbin, Adam D., Mark W. Zimmerman, Neekesh V. Dharia, et al.. (2018). Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nature Genetics. 50(9). 1240–1246. 145 indexed citations
4.
Lo, Justin H., Liangliang Hao, Mandar D. Muzumdar, et al.. (2018). iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer. Molecular Cancer Therapeutics. 17(11). 2377–2388. 65 indexed citations
5.
Hsu, Jessie Hao-Ru, Guillaume Adelmant, Jialiang Huang, et al.. (2017). PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Research. 77(17). 4613–4625. 26 indexed citations
6.
Sandoval, Gabriel J. & William C. Hahn. (2017). Going beyond genetics to discover cancer targets. Genome biology. 18(1). 95–95. 1 indexed citations
7.
Choudhury, Atish D., Anna C. Schinzel, Maura B. Cotter, et al.. (2016). Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6. Cancer Research. 77(3). 753–765. 30 indexed citations
8.
Konieczkowski, David J., Cory M. Johannessen, Omar O. Abudayyeh, et al.. (2014). A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors. Cancer Discovery. 4(7). 816–827. 357 indexed citations breakdown →
9.
Luo, Leo Y., Eejung Kim, Hiu Wing Cheung, et al.. (2014). The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer. Molecular Cancer Research. 13(3). 502–509. 29 indexed citations
10.
Etemadmoghadam, Dariush, George Au‐Yeung, Meaghan Wall, et al.. (2013). Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1 -Amplified Ovarian Cancer. Clinical Cancer Research. 19(21). 5960–5971. 90 indexed citations
11.
Etemadmoghadam, Dariush, Barbara A. Weir, George Au‐Yeung, et al.. (2013). Synthetic lethality between CCNE1 amplification and loss of BRCA1. Proceedings of the National Academy of Sciences. 110(48). 19489–19494. 157 indexed citations
12.
Ren, Yin, Hiu Wing Cheung, Amit Agrawal, et al.. (2012). Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4. Science Translational Medicine. 4(147). 147ra112–147ra112. 134 indexed citations
13.
Lund, Per, Irina Kotova, Valérie Kedinger, et al.. (2011). Transformation-Dependent Silencing of Tumor-Selective Apoptosis-Inducing TRAIL by DNA Hypermethylation Is Antagonized by Decitabine. Molecular Cancer Therapeutics. 10(9). 1611–1623. 16 indexed citations
14.
Wagle, Nikhil, Michael F. Berger, Matthew J. Davis, et al.. (2011). Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling. Journal of Clinical Oncology. 29(22). 3085–3096. 732 indexed citations breakdown →
15.
Wagle, Nikhil, Michael F. Berger, Matthew J. Davis, et al.. (2011). High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing. Cancer Discovery. 2(1). 82–93. 384 indexed citations
16.
Jané‐Valbuena, Judit, Hans R. Widlund, Sven Perner, et al.. (2010). An Oncogenic Role for ETV1 in Melanoma. Cancer Research. 70(5). 2075–2084. 81 indexed citations
17.
Badalian‐Very, Gayane, Jo‐Anne Vergilio, Barbara Degar, et al.. (2010). Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 116(11). 1919–1923. 742 indexed citations breakdown →
18.
Balakumaran, Bala S., Alessandro Porrello, David S. Hsu, et al.. (2009). MYC Activity Mitigates Response to Rapamycin in Prostate Cancer through Eukaryotic Initiation Factor 4E–Binding Protein 1–Mediated Inhibition of Autophagy. Cancer Research. 69(19). 7803–7810. 60 indexed citations
19.
Moreno, Carlos S., Sumathi Ramachandran, Danita G. Ashby, et al.. (2004). Signaling and Transcriptional Changes Critical for Transformation of Human Cells by Simian Virus 40 Small Tumor Antigen or Protein Phosphatase 2A B56γ Knockdown. Cancer Research. 64(19). 6978–6988. 44 indexed citations
20.
Berger, Raanan, Phillip G. Febbo, Pradip K. Majumder, et al.. (2004). Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells. Cancer Research. 64(24). 8867–8875. 140 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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