James D. Orth

4.0k total citations · 1 hit paper
31 papers, 3.3k citations indexed

About

James D. Orth is a scholar working on Cell Biology, Molecular Biology and Oncology. According to data from OpenAlex, James D. Orth has authored 31 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Cell Biology, 20 papers in Molecular Biology and 8 papers in Oncology. Recurrent topics in James D. Orth's work include Microtubule and mitosis dynamics (9 papers), Cellular transport and secretion (8 papers) and Cellular Mechanics and Interactions (8 papers). James D. Orth is often cited by papers focused on Microtubule and mitosis dynamics (9 papers), Cellular transport and secretion (8 papers) and Cellular Mechanics and Interactions (8 papers). James D. Orth collaborates with scholars based in United States, Australia and Hong Kong. James D. Orth's co-authors include Mark A. McNiven, Hong Cao, Eugene W. Krueger, Roberto Buccione, Timothy J. Mitchison, Jue Shi, Shaun G. Weller, Tim Mitchison, Tai W. Wong and Alexander Loewer and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

James D. Orth

30 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

2004 500 citations Roberto Buccione, James D. Orth et al. Nature Reviews Molecular Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James D. Orth United States	21	2.1k	1.9k	551	474	262	31	3.3k
Xi Zhan United States	31	1.7k 0.8×	2.0k 1.0×	400 0.7×	741 1.6×	264 1.0×	58	3.6k
Pierfrancesco Marra Italy	12	1.6k 0.8×	1.7k 0.9×	295 0.5×	212 0.4×	223 0.9×	18	2.6k
Violaine Moreau France	28	1.7k 0.8×	1.7k 0.9×	338 0.6×	560 1.2×	106 0.4×	59	3.2k
Torsten Wittmann United States	35	3.1k 1.5×	3.1k 1.6×	440 0.8×	281 0.6×	162 0.6×	62	5.0k
Andrei V. Karginov United States	24	1.5k 0.7×	1.6k 0.8×	188 0.3×	640 1.4×	234 0.9×	43	2.9k
Toshiki Itoh Japan	32	1.9k 0.9×	2.9k 1.5×	325 0.6×	255 0.5×	329 1.3×	75	4.0k
Etsuko Kiyokawa Japan	31	985 0.5×	2.3k 1.2×	287 0.5×	455 1.0×	288 1.1×	71	3.4k
Inés M. Antón Spain	28	1.6k 0.8×	1.2k 0.6×	337 0.6×	869 1.8×	104 0.4×	50	2.9k
Jan Gettemans Belgium	32	1.2k 0.6×	2.1k 1.1×	319 0.6×	241 0.5×	133 0.5×	94	3.3k
Frédéric Bard Singapore	31	1.4k 0.7×	2.9k 1.5×	398 0.7×	230 0.5×	194 0.7×	56	3.9k

Countries citing papers authored by James D. Orth

Since Specialization

Citations

This map shows the geographic impact of James D. Orth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James D. Orth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James D. Orth more than expected).

Fields of papers citing papers by James D. Orth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James D. Orth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James D. Orth. The network helps show where James D. Orth may publish in the future.

Co-authorship network of co-authors of James D. Orth

This figure shows the co-authorship network connecting the top 25 collaborators of James D. Orth. A scholar is included among the top collaborators of James D. Orth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James D. Orth. James D. Orth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Le, Linh T. T., et al.. (2025). Spatial mechanisms of quality control during chaperone-mediated assembly of the proteasome. Nature Communications. 16(1). 3358–3358.

Orth, James D., et al.. (2022). Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones. Cell Reports. 39(10). 110918–110918. 8 indexed citations

Orth, James D., et al.. (2019). Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases. Journal of Biological Chemistry. 294(16). 6562–6577. 11 indexed citations

Burke, Russell T. & James D. Orth. (2016). Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics. Journal of Visualized Experiments. 7 indexed citations

Burke, Russell T., et al.. (2015). Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor. Scientific Reports. 5(1). 14391–14391. 23 indexed citations

Chittajallu, Deepak R., Stefan Florian, Rainer H. Köhler, et al.. (2015). In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy. Nature Methods. 12(6). 577–585. 65 indexed citations

Laughney, Ashley M., Eunha Kim, Melissa M. Sprachman, et al.. (2014). Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Science Translational Medicine. 6(261). 261ra152–261ra152. 62 indexed citations

Orth, James D., Rainer H. Köhler, Floris Foijer, et al.. (2011). Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics. Cancer Research. 71(13). 4608–4616. 120 indexed citations

Orth, James D., et al.. (2011). Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer Letters. 310(1). 15–24. 13 indexed citations

10.

Shi, Jue, et al.. (2009). Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly. Cancer Cell. 16(4). 347–358. 240 indexed citations

11.

Xie, Tiao, et al.. (2009). An Intermittent Live Cell Imaging Screen for siRNA Enhancers and Suppressors of a Kinesin-5 Inhibitor. PLoS ONE. 4(10). e7339–e7339. 21 indexed citations

12.

Orth, James D., Jue Shi, Clement T. Loy, et al.. (2008). Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Molecular Cancer Therapeutics. 7(11). 3480–3489. 91 indexed citations

13.

Shi, Jue, James D. Orth, & Tim Mitchison. (2008). Cell Type Variation in Responses to Antimitotic Drugs that Target Microtubules and Kinesin-5. Cancer Research. 68(9). 3269–3276. 168 indexed citations

14.

Orth, James D., Eugene W. Krueger, Shaun G. Weller, & Mark A. McNiven. (2006). A Novel Endocytic Mechanism of Epidermal Growth Factor Receptor Sequestration and Internalization. Cancer Research. 66(7). 3603–3610. 180 indexed citations

15.

Cao, Hong, Shaun G. Weller, James D. Orth, et al.. (2005). Actin and Arf1-dependent recruitment of a cortactin–dynamin complex to the Golgi regulates post-Golgi transport. Nature Cell Biology. 7(5). 483–492. 147 indexed citations

16.

Buccione, Roberto, James D. Orth, & Mark A. McNiven. (2004). Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nature Reviews Molecular Cell Biology. 5(8). 647–657. 500 indexed citations breakdown →

17.

Orth, James D. & Mark A. McNiven. (2003). Dynamin at the actin–membrane interface. Current Opinion in Cell Biology. 15(1). 31–39. 197 indexed citations

18.

Cao, Hong, James D. Orth, Jing Chen, et al.. (2003). Cortactin Is a Component of Clathrin-Coated Pits and Participates in Receptor-Mediated Endocytosis. Molecular and Cellular Biology. 23(6). 2162–2170. 172 indexed citations

19.

Krueger, Eugene W., James D. Orth, Hong Cao, & Mark A. McNiven. (2003). A Dynamin–Cortactin–Arp2/3 Complex Mediates Actin Reorganization in Growth Factor-stimulated Cells. Molecular Biology of the Cell. 14(3). 1085–1096. 178 indexed citations

20.

Orth, James D., et al.. (1999). Testis-Specific Murine Centrin, Cetn1: Genomic Characterization and Evidence for Retroposition of a Gene Encoding a Centrosome Protein. Genomics. 60(2). 111–120. 73 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact