Timothy J. Mitchison

53.1k total citations · 17 hit papers
282 papers, 41.2k citations indexed

About

Timothy J. Mitchison is a scholar working on Molecular Biology, Cell Biology and Plant Science. According to data from OpenAlex, Timothy J. Mitchison has authored 282 papers receiving a total of 41.2k indexed citations (citations by other indexed papers that have themselves been cited), including 213 papers in Molecular Biology, 187 papers in Cell Biology and 27 papers in Plant Science. Recurrent topics in Timothy J. Mitchison's work include Microtubule and mitosis dynamics (171 papers), Photosynthetic Processes and Mechanisms (54 papers) and Cellular Mechanics and Interactions (41 papers). Timothy J. Mitchison is often cited by papers focused on Microtubule and mitosis dynamics (171 papers), Photosynthetic Processes and Mechanisms (54 papers) and Cellular Mechanics and Interactions (41 papers). Timothy J. Mitchison collaborates with scholars based in United States, Germany and United Kingdom. Timothy J. Mitchison's co-authors include Arshad Desai, Adrian Salic, Anthony A. Hyman, Kenneth E. Sawin, Christine M. Field, Tarun M. Kapoor, Julie A. Theriot, Marc W. Kirschner, Edward D. Salmon and Margaret Coughlin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Timothy J. Mitchison

275 papers receiving 40.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

2005 2.4k citations Timothy J. Mitchison et al. profile →
MICROTUBULE POLYMERIZATION DYNAMICS

1997 2.0k citations Timothy J. Mitchison et al. profile →
A chemical method for fast and sensitive detection of DNA synthesis in vivo

2008 1.5k citations Adrian Salic, Timothy J. Mitchison Proceedings of the National Academy of Sciences profile →
Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

1999 1.5k citations Stephen J. Haggarty, Timothy J. Mitchison et al. Science profile →
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

2009 1.2k citations Timothy J. Mitchison et al. profile →
Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor

2003 1.2k citations Aaron F. Straight, Amy Cheung et al. Science profile →
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

2011 949 citations Clifford P. Brangwynne, Timothy J. Mitchison et al. Proceedings of the National Academy of Sciences profile →
Actin microfilament dynamics in locomoting cells

1991 661 citations Timothy J. Mitchison et al. profile →
Identification of a Protein That Interacts with Tubulin Dimers and Increases the Catastrophe Rate of Microtubules

1996 581 citations Timothy J. Mitchison et al. profile →
Kin I Kinesins Are Microtubule-Destabilizing Enzymes

1999 578 citations Timothy J. Mitchison et al. profile →
Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

2000 575 citations Margaret Coughlin, Timothy J. Mitchison et al. The Journal of Cell Biology profile →
Mitotic spindle organization by a plus-end-directed microtubule motor

1992 546 citations Timothy J. Mitchison et al. profile →
Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

1989 511 citations Timothy J. Mitchison The Journal of Cell Biology profile →
Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes

1997 503 citations Timothy J. Mitchison et al. profile →
Multidimensional Drug Profiling By Automated Microscopy

2004 503 citations Timothy J. Mitchison et al. Science profile →
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization

1992 426 citations Timothy J. Mitchison et al. profile →
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

2018 370 citations Timothy J. Mitchison et al. profile →

Peers

Timothy J. Mitchison

ONCOL

IMMUN

Ronald D. Vale United States

Gary G. Borisy United States

Axel T. Brünger United States

Kai Simons Germany

Juan S. Bonifacino United States

David A. Agard United States

Robert G. Parton Australia

Michael P. Sheetz United States

Jonathan S. Weissman United States

Eisuke Nishida Japan

Ronald D. Vale United States

Timothy J. Mitchison

23.0k ×0.8

18.6k ×0.9

2.5k ×0.7

ONCOL

2.5k ×0.7

3.0k ×1.1

IMMUN

Citations per year, relative to Timothy J. Mitchison Timothy J. Mitchison (= 1×) peers Ronald D. Vale

Countries citing papers authored by Timothy J. Mitchison

Since Specialization

Citations

This map shows the geographic impact of Timothy J. Mitchison's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy J. Mitchison with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy J. Mitchison more than expected).

Fields of papers citing papers by Timothy J. Mitchison

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy J. Mitchison. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy J. Mitchison. The network helps show where Timothy J. Mitchison may publish in the future.

Co-authorship network of co-authors of Timothy J. Mitchison

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy J. Mitchison. A scholar is included among the top collaborators of Timothy J. Mitchison based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy J. Mitchison. Timothy J. Mitchison is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Koch, Peter D., et al.. (2021). Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells. Proceedings of the National Academy of Sciences. 118(48). 77 indexed citations

Shimada, Kaoru, John A. Bachman, Jeremy L. Muhlich, & Timothy J. Mitchison. (2021). shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data. eLife. 10. 51 indexed citations

Li, Ran, Stephanie Wang, Mark Prytyskach, et al.. (2020). In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells. Nature Communications. 11(1). 3521–3521. 19 indexed citations

Silva, M. Catarina, Fleur M. Ferguson, Quan-Ying Cai, et al.. (2019). Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. eLife. 8. 203 indexed citations

Lin, Zhewang, Ivana Gasic, Viswanathan Chandrasekaran, et al.. (2019). TTC5 mediates autoregulation of tubulin via mRNA degradation. Science. 367(6473). 100–104. 82 indexed citations

Choi, Paul & Timothy J. Mitchison. (2013). Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells. Proceedings of the National Academy of Sciences. 110(16). 6488–6493. 94 indexed citations

Mitchison, Timothy J., Phuong Nguyen, Margaret Coughlin, & Aaron C. Groen. (2013). Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. Molecular Biology of the Cell. 24(10). 1559–1573. 31 indexed citations

Dumont, Sophie, Edward D. Salmon, & Timothy J. Mitchison. (2012). Deformations Within Moving Kinetochores Reveal Different Sites of Active and Passive Force Generation. Science. 337(6092). 355–358. 75 indexed citations

Orth, James D., Rainer H. Köhler, Floris Foijer, et al.. (2011). Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics. Cancer Research. 71(13). 4608–4616. 120 indexed citations

10.

Field, Christine M., Martin Wühr, Graham A. Anderson, et al.. (2011). Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos. Journal of Cell Science. 124(12). 2086–2095. 66 indexed citations

11.

Shi, Jue, et al.. (2011). Navitoclax (ABT-263) Accelerates Apoptosis during Drug-Induced Mitotic Arrest by Antagonizing Bcl-xL. Cancer Research. 71(13). 4518–4526. 102 indexed citations

12.

Brangwynne, Clifford P., Timothy J. Mitchison, & Anthony A. Hyman. (2011). Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences. 108(11). 4334–4339. 949 indexed citations breakdown →

13.

Orth, James D., Jue Shi, Clement T. Loy, et al.. (2008). Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Molecular Cancer Therapeutics. 7(11). 3480–3489. 91 indexed citations

14.

Salic, Adrian & Timothy J. Mitchison. (2008). A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proceedings of the National Academy of Sciences. 105(7). 2415–2420. 1460 indexed citations breakdown →

15.

Eggert, Ulrike, Christine M. Field, & Timothy J. Mitchison. (2005). Small molecules in an RNAi world. Molecular BioSystems. 2(2). 93–96. 18 indexed citations

16.

Carey, Kimberly L., Nicholas J. Westwood, Timothy J. Mitchison, & Gary E. Ward. (2004). A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii. Proceedings of the National Academy of Sciences. 101(19). 7433–7438. 97 indexed citations

17.

Straight, Aaron F., Christine M. Field, & Timothy J. Mitchison. (2004). Anillin Binds Nonmuscle Myosin II and Regulates the Contractile Ring. Molecular Biology of the Cell. 16(1). 193–201. 219 indexed citations

18.

Maddox, Paul S., et al.. (2003). Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles. The Journal of Cell Biology. 162(3). 377–382. 157 indexed citations

19.

Cheung, Amy, Nicholas J. Westwood, Irene A. Chen, Timothy J. Mitchison, & Aaron F. Straight. (2001). Blebbistatin A cell permeable inhibitor of non-muscle myosin II. Molecular Biology of the Cell. 12. 271. 4 indexed citations

20.

Cramer, Louise P. & Timothy J. Mitchison. (1992). ACTIN FILAMENT DYNAMICS IN SPREADING MITOTIC CELLS. UCL Discovery (University College London). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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