Timothy J. Mitchison

53.1k total citations · 17 hit papers
282 papers, 41.2k citations indexed

About

Timothy J. Mitchison is a scholar working on Molecular Biology, Cell Biology and Plant Science. According to data from OpenAlex, Timothy J. Mitchison has authored 282 papers receiving a total of 41.2k indexed citations (citations by other indexed papers that have themselves been cited), including 213 papers in Molecular Biology, 187 papers in Cell Biology and 27 papers in Plant Science. Recurrent topics in Timothy J. Mitchison's work include Microtubule and mitosis dynamics (171 papers), Photosynthetic Processes and Mechanisms (54 papers) and Cellular Mechanics and Interactions (41 papers). Timothy J. Mitchison is often cited by papers focused on Microtubule and mitosis dynamics (171 papers), Photosynthetic Processes and Mechanisms (54 papers) and Cellular Mechanics and Interactions (41 papers). Timothy J. Mitchison collaborates with scholars based in United States, Germany and United Kingdom. Timothy J. Mitchison's co-authors include Arshad Desai, Adrian Salic, Anthony A. Hyman, Kenneth E. Sawin, Christine M. Field, Tarun M. Kapoor, Julie A. Theriot, Marc W. Kirschner, Edward D. Salmon and Margaret Coughlin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Timothy J. Mitchison

275 papers receiving 40.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

2005 2.4k citations Timothy J. Mitchison et al. profile →
MICROTUBULE POLYMERIZATION DYNAMICS

1997 2.0k citations Timothy J. Mitchison et al. profile →
A chemical method for fast and sensitive detection of DNA synthesis in vivo

2008 1.5k citations Adrian Salic, Timothy J. Mitchison Proceedings of the National Academy of Sciences profile →
Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

1999 1.5k citations Stephen J. Haggarty, Timothy J. Mitchison et al. Science profile →
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

2009 1.2k citations Timothy J. Mitchison et al. profile →
Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor

2003 1.2k citations Aaron F. Straight, Amy Cheung et al. Science profile →
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

2011 949 citations Clifford P. Brangwynne, Timothy J. Mitchison et al. Proceedings of the National Academy of Sciences profile →
Actin microfilament dynamics in locomoting cells

1991 661 citations Timothy J. Mitchison et al. profile →
Identification of a Protein That Interacts with Tubulin Dimers and Increases the Catastrophe Rate of Microtubules

1996 581 citations Timothy J. Mitchison et al. profile →
Kin I Kinesins Are Microtubule-Destabilizing Enzymes

1999 578 citations Timothy J. Mitchison et al. profile →
Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

2000 575 citations Margaret Coughlin, Timothy J. Mitchison et al. The Journal of Cell Biology profile →
Mitotic spindle organization by a plus-end-directed microtubule motor

1992 546 citations Timothy J. Mitchison et al. profile →
Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

1989 511 citations Timothy J. Mitchison The Journal of Cell Biology profile →
Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes

1997 503 citations Timothy J. Mitchison et al. profile →
Multidimensional Drug Profiling By Automated Microscopy

2004 503 citations Timothy J. Mitchison et al. Science profile →
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization

1992 426 citations Timothy J. Mitchison et al. profile →
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

2018 370 citations Timothy J. Mitchison et al. profile →

Peers

Countries citing papers authored by Timothy J. Mitchison

Since Specialization

Citations

This map shows the geographic impact of Timothy J. Mitchison's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy J. Mitchison with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy J. Mitchison more than expected).

Fields of papers citing papers by Timothy J. Mitchison

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy J. Mitchison. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy J. Mitchison. The network helps show where Timothy J. Mitchison may publish in the future.

Co-authorship network of co-authors of Timothy J. Mitchison

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy J. Mitchison. A scholar is included among the top collaborators of Timothy J. Mitchison based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy J. Mitchison. Timothy J. Mitchison is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells 2021 ·Proceedings of the National Academy of Sciences ·(unknown), Peter D. Koch, Timothy J. Mitchison	77
2	shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data 2021 ·eLife ·Kaoru Shimada, John A. Bachman, Jeremy L. Muhlich, Timothy J. Mitchison	51
3	In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells 2020 ·Nature Communications ·(unknown), Ran Li, Stephanie Wang, Mark Prytyskach, Rainer H. Köhler, Douglas A. Lauffenburger, Timothy J. Mitchison, Ralph Weissleder, Miles A. Miller	19
4	Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models 2019 ·eLife ·M. Catarina Silva, Fleur M. Ferguson, Quan-Ying Cai, Katherine A. Donovan, (unknown), Debasis Patnaik, Tinghu Zhang, Hai‐Tsang Huang, Diane Lucente, Bradford C. Dickerson, Timothy J. Mitchison, Eric S. Fischer, Nathanael S. Gray, Stephen J. Haggarty	203
5	TTC5 mediates autoregulation of tubulin via mRNA degradation 2019 ·Science ·Zhewang Lin, Ivana Gasic, Viswanathan Chandrasekaran, (unknown), Sichen Shao, Timothy J. Mitchison, Ramanujan S. Hegde	82
6	Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells 2013 ·Proceedings of the National Academy of Sciences ·Paul Choi, Timothy J. Mitchison	94
7	Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol 2013 ·Molecular Biology of the Cell ·Timothy J. Mitchison, Phuong Nguyen, Margaret Coughlin, Aaron C. Groen	31
8	Deformations Within Moving Kinetochores Reveal Different Sites of Active and Passive Force Generation 2012 ·Science ·Sophie Dumont, Edward D. Salmon, Timothy J. Mitchison	75
9	Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics 2011 ·Cancer Research ·James D. Orth, Rainer H. Köhler, Floris Foijer, Peter K. Sorger, Ralph Weissleder, Timothy J. Mitchison	120
10	Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos 2011 ·Journal of Cell Science ·Christine M. Field, Martin Wühr, Graham A. Anderson, Hao Yuan Kueh, Devin Strickland, Timothy J. Mitchison	66
11	Navitoclax (ABT-263) Accelerates Apoptosis during Drug-Induced Mitotic Arrest by Antagonizing Bcl-xL 2011 ·Cancer Research ·Jue Shi, Yuan Zhou, (unknown), Timothy J. Mitchison	102
12	Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes breakdown → 2011 ·Proceedings of the National Academy of Sciences ·Clifford P. Brangwynne, Timothy J. Mitchison, Anthony A. Hyman	949
13	Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate 2008 ·Molecular Cancer Therapeutics ·James D. Orth, (unknown), Jue Shi, Clement T. Loy, Christiane Amendt, Claudia Wilm, Frank T. Zenke, Timothy J. Mitchison	91
14	A chemical method for fast and sensitive detection of DNA synthesis in vivo breakdown → 2008 ·Proceedings of the National Academy of Sciences ·Adrian Salic, Timothy J. Mitchison	1460
15	Small molecules in an RNAi world 2005 ·Molecular BioSystems ·Ulrike Eggert, Christine M. Field, Timothy J. Mitchison	18
16	A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii 2004 ·Proceedings of the National Academy of Sciences ·Kimberly L. Carey, Nicholas J. Westwood, Timothy J. Mitchison, Gary E. Ward	97
17	Anillin Binds Nonmuscle Myosin II and Regulates the Contractile Ring 2004 ·Molecular Biology of the Cell ·Aaron F. Straight, Christine M. Field, Timothy J. Mitchison	219
18	Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles 2003 ·The Journal of Cell Biology ·Paul S. Maddox, Aaron F. Straight, (unknown), Timothy J. Mitchison, Edward D. Salmon	157
19	Blebbistatin A cell permeable inhibitor of non-muscle myosin II 2001 ·Molecular Biology of the Cell ·Amy Cheung, Nicholas J. Westwood, Irene A. Chen, Timothy J. Mitchison, Aaron F. Straight	4
20	ACTIN FILAMENT DYNAMICS IN SPREADING MITOTIC CELLS 1992 ·UCL Discovery (University College London) ·Louise P. Cramer, Timothy J. Mitchison	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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