M. Celeste Simon

62.8k total citations · 24 hit papers
262 papers, 47.7k citations indexed

About

M. Celeste Simon is a scholar working on Cancer Research, Molecular Biology and Oncology. According to data from OpenAlex, M. Celeste Simon has authored 262 papers receiving a total of 47.7k indexed citations (citations by other indexed papers that have themselves been cited), including 168 papers in Cancer Research, 151 papers in Molecular Biology and 45 papers in Oncology. Recurrent topics in M. Celeste Simon's work include Cancer, Hypoxia, and Metabolism (156 papers), Epigenetics and DNA Methylation (31 papers) and High Altitude and Hypoxia (21 papers). M. Celeste Simon is often cited by papers focused on Cancer, Hypoxia, and Metabolism (156 papers), Epigenetics and DNA Methylation (31 papers) and High Altitude and Hypoxia (21 papers). M. Celeste Simon collaborates with scholars based in United States, Slovakia and China. M. Celeste Simon's co-authors include Brian Keith, Randall S. Johnson, Nicole Anderson, John D. Gordan, Amar J. Majmundar, Waihay J. Wong, Craig B. Thompson, Cheng‐Jun Hu, Shetal Patel and Navdeep S. Chandel and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

M. Celeste Simon

258 papers receiving 47.1k citations

Hit Papers

Hypoxia-Inducible Factors and the Response ... 1994 2026 2004 2015 2010 2020 2005 1998 2011 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Hypoxia-Inducible Factors and the Response to Hypoxic Stress
    2010 1.9k citations M. Celeste Simon et al. profile →
  2. The tumor microenvironment
    2020 1.7k citations Nicole Anderson, M. Celeste Simon profile →
  3. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
    2005 1.6k citations M. Celeste Simon et al. profile →
  4. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
    1998 1.6k citations Navdeep S. Chandel, Emin Maltepe et al. profile →
  5. HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
    2011 1.4k citations Brian Keith, M. Celeste Simon et al. profile →
  6. Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
    1996 1.3k citations M. Celeste Simon et al. profile →
  7. Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals
    2000 1.3k citations M. Celeste Simon et al. profile →
  8. Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages
    1994 1.2k citations M. Celeste Simon et al. profile →
  9. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
    2005 1.2k citations M. Celeste Simon et al. profile →
  10. Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation
    2003 1.1k citations Brian Keith, M. Celeste Simon et al. Molecular and Cellular Biology profile →
  11. The impact of O2 availability on human cancer
    2008 1.1k citations Jessica A. Bertout, Shetal Patel et al. profile →
  12. Hypoxia-Inducible Factors, Stem Cells, and Cancer
    2007 935 citations Brian Keith, M. Celeste Simon profile →
  13. Glutathione metabolism in cancer progression and treatment resistance
    2018 927 citations Ankita Bansal, M. Celeste Simon The Journal of Cell Biology profile →
  14. Hypoxia-Induced Angiogenesis: Good and Evil
    2011 909 citations M. Celeste Simon et al. profile →
  15. Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
    2020 807 citations Pearl Lee, Navdeep S. Chandel et al. Nature Reviews Molecular Cell Biology profile →
  16. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
    2011 791 citations Jessica E.S. Shay, M. Celeste Simon et al. profile →
  17. The role of oxygen availability in embryonic development and stem cell function
    2008 735 citations M. Celeste Simon, Brian Keith Nature Reviews Molecular Cell Biology profile →
  18. HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
    2006 657 citations Kelly L. Covello, John D. Gordan et al. profile →
  19. HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation
    2007 623 citations John D. Gordan, M. Celeste Simon et al. profile →
  20. HIF-2α Promotes Hypoxic Cell Proliferation by Enhancing c-Myc Transcriptional Activity
    2007 619 citations John D. Gordan, Jessica A. Bertout et al. profile →
  21. Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation
    2005 517 citations M. Celeste Simon et al. profile →
  22. Hypoxia-Induced Energy Stress Regulates mRNA Translation and Cell Growth
    2006 506 citations Brian Keith, M. Celeste Simon et al. profile →
  23. Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
    2010 501 citations M. Celeste Simon et al. profile →
  24. Fructose-1,6-bisphosphatase opposes renal carcinoma progression
    2014 404 citations Lijoy K. Mathew, Brian Keith et al. Nature profile →

Peers

M. Celeste Simon
Comparison fields: 5 of 175
  • Molecular Biology 26.3k
  • Cancer Research 21.1k
  • Immunology 7.2k
  • Oncology 7.1k
  • Physiology 5.1k
Replace Chi V. Dang with:
Chi V. Dang United States
Matthew G. Vander Heiden United States
Amato J. Giaccia United States
Carlos López-Otı́n Spain
William G. Kaelin United States
Pier Paolo Pandolfi United States
Jacques Pouysségur France
Richard G. Pestell United States
John M. Asara United States
Scott W. Lowe United States
Chi V. Dang United States View profile →
Citations per field, relative to M. Celeste Simon
M. Celeste Simon · 1×
Citations per year, relative to M. Celeste Simon
M. Celeste Simon · 1×

Countries citing papers authored by M. Celeste Simon

Since Specialization
Citations

This map shows the geographic impact of M. Celeste Simon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by M. Celeste Simon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites M. Celeste Simon more than expected).

Fields of papers citing papers by M. Celeste Simon

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by M. Celeste Simon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by M. Celeste Simon. The network helps show where M. Celeste Simon may publish in the future.

Co-authorship network of co-authors of M. Celeste Simon

This figure shows the co-authorship network connecting the top 25 collaborators of M. Celeste Simon. A scholar is included among the top collaborators of M. Celeste Simon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with M. Celeste Simon. M. Celeste Simon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
# Work Indexed citations
1
Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer
2024 ·Nature Cancer ·Fuming Li, Pingyu Liu, Mi Wen, Liucheng Li, Nicole Anderson, Nicholas P. Lesner, Michelle Burrows, (unknown), (unknown), Guanlin Wang, Jinyang Li, (unknown), Brian Keith, M. Celeste Simon
37
2
Disrupting cellular memory to overcome drug resistance
2023 ·Nature Communications ·Guillaume Harmange, (unknown), (unknown), Benjamin Emert, (unknown), Laura C. Kim, (unknown), (unknown), Mitchell E. Fane, Gretchen M. Alicea, Ashani T. Weeraratna, M. Celeste Simon, Abhyudai Singh, Sydney M. Shaffer
26
3
RALDH1 Inhibition Shows Immunotherapeutic Efficacy in Hepatocellular Carcinoma
2023 ·Cancer Immunology Research ·Pengfei Yu, Shuwen Cao, Shyh‐Ming Yang, Ganesha Rai, Natalia J. Martinez, Adam Yasgar, Alexey Zakharov, Anton Simeonov, (unknown), (unknown), (unknown), (unknown), (unknown), Emma E. Furth, M. Celeste Simon, Malay Haldar
2
4
HIF : a master regulator of nutrient availability and metabolic cross‐talk in the tumor microenvironment
2023 ·The EMBO Journal ·Rindert Missiaen, Nicholas P. Lesner, M. Celeste Simon
36
5
Activation of γ-globin expression by hypoxia-inducible factor 1α
2022 ·Nature ·Ruopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, Phillip A. Doerfler, Yichao Li, Yu Yao, Jingjing Zhang, Lance E. Palmer, Kalin Mayberry, Georgios E. Christakopoulos, Peng Xu, Chunliang Li, Yong Cheng, Gerd A. Blobel, M. Celeste Simon, Mitchell J. Weiss
37
6
m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype
2021 ·Nature Cell Biology ·Pingyu Liu, Fuming Li, Jianhuang Lin, Takeshi Fukumoto, Timothy Nacarelli, Hao Xue, Andrew V. Kossenkov, M. Celeste Simon, Rugang Zhang
118
7
Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial Carcinoma
2021 ·Molecular Cancer Research ·Danielle J. Sanchez, Rindert Missiaen, Nicolas Skuli, David J. Steger, M. Celeste Simon
9
8
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma
2021 ·Cancer Research ·Nicole Anderson, Xiaodan Qin, Jennifer M. Finan, (unknown), (unknown), Rindert Missiaen, Nicolas Skuli, (unknown), (unknown), Ting Tao, Shizhen Zhu, Itzhak Nissim, A. Thomas Look, Guoliang Qing, M. Celeste Simon, Hui Feng
44
9
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond breakdown →
2020 ·Nature Reviews Molecular Cell Biology ·Pearl Lee, Navdeep S. Chandel, M. Celeste Simon
807
10
Gamma-Glutamyltransferase 1 Promotes Clear Cell Renal Cell Carcinoma Initiation and Progression
2019 ·Molecular Cancer Research ·Ankita Bansal, Danielle J. Sanchez, (unknown), (unknown), Romain Riscal, Nicolas Skuli, M. Celeste Simon
35
11
Glutathione metabolism in cancer progression and treatment resistance breakdown →
2018 ·The Journal of Cell Biology ·Ankita Bansal, M. Celeste Simon
927
12
Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia
2015 ·Cancer Discovery ·Kyoung Eun Lee, Michelle Spata, Lauren J. Bayne, Elizabeth L. Buza, Amy C. Durham, David Allman, Robert H. Vonderheide, M. Celeste Simon
179
13
Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma
2015 ·Molecular Cancer Research ·Alice M. Walsh, Gurpreet S. Kapoor, Janine M. Buonato, Lijoy K. Mathew, Yingtao Bi, Ramana V. Davuluri, María Martínez-Lage, M. Celeste Simon, Donald M. O’Rourke, Matthew J. Lazzara
24
14
Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis
2013 ·Cancer Discovery ·T.S. Karin Eisinger‐Mathason, Minsi Zhang, Qiong Qiu, Nicolas Skuli, Michael S. Nakazawa, Tatiana A. Karakasheva, Vera Mucaj, Jessica E.S. Shay, Lars Stangenberg, Navid Sadri, Ellen Puré, Sam S. Yoon, David G. Kirsch, M. Celeste Simon
213
15
Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
2013 ·Cancer Research ·Silvia Licciulli, Jacqueline L. Avila, Linda Hanlon, Scott Troutman, Matteo Cesaroni, Smitha Kota, Brian Keith, M. Celeste Simon, Ellen Puré, Freddy Radtke, Anthony J. Capobianco, Joseph L. Kissil
93
16
Integrative Genomic Analyses of Sporadic Clear Cell Renal Cell Carcinoma Define Disease Subtypes and Potential New Therapeutic Targets
2011 ·Cancer Research ·Vijay R. Dondeti, Bradley Wubbenhorst, Priti Lal, John D. Gordan, Kurt D’Andrea, Edward F. Attiyeh, M. Celeste Simon, Katherine L. Nathanson
43
17
Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1α
2010 ·Cancer Research ·Guoliang Qing, Nicolas Skuli, Patrick A. Mayes, Bruce Pawel, Daniel Martínez, John M. Maris, M. Celeste Simon
128
18
Heterozygosity for Hypoxia Inducible Factor 1α Decreases the Incidence of Thymic Lymphomas in a p53 Mutant Mouse Model
2009 ·Cancer Research ·Jessica A. Bertout, Shetal Patel, Benjamin H. Fryer, Amy C. Durham, Kelly L. Covello, Kenneth P. Olive, Michael H. Goldschmidt, M. Celeste Simon
28
19
Hypoxia-Inducible Factors 1α and 2α Regulate Trophoblast Differentiation
2005 ·Molecular and Cellular Biology ·Karen D. Cowden Dahl, Benjamin H. Fryer, Fiona Mack, Veerle Compernolle, Emin Maltepe, David M. Adelman, Peter Carmeliet, M. Celeste Simon
185
20
The importance of PU.1 concentration in hematopoietic lineage commitment and maturation
2003 ·Blood Cells Molecules and Diseases ·Richard Dahl, M. Celeste Simon
66

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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