Brian J. Abraham

27.6k citations

54 papers · 13.2k indexed · 10 hit papers · h-index 35

Molecular Biology top 0.2%
Cancer Research top 0.5%
Oncology top 2%
Immunology top 2%
Genetics top 1%

Co-authors: Denes Hnisz Richard A. Young Tong Ihn Lee Alla A. Sigova Charles Y. Lin Violaine Saint‐André David A. Orlando Peter B. Rahl
Topics: Genomics and Chromatin Dynamics (22 papers)Protein Degradation and Inhibitors (17 papers)Neuroblastoma Research and Treatments (15 papers)
Cited by: Molecular Biology Cancer Research Immunology
Journals: Nature Science Cell
Partner nations: United States China United Kingdom

In The Last Decade

Brian J. Abraham

54 papers receiving 13.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

2013 2.7k citations Denes Hnisz, Brian J. Abraham et al. Cell profile →
Super-Enhancers in the Control of Cell Identity and Disease

2013 2.4k citations Denes Hnisz, Brian J. Abraham et al. Cell profile →
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

2018 1.2k citations Alessandra Dall’Agnese, Nancy M. Hannett et al. Cell profile →
YY1 Is a Structural Regulator of Enhancer-Promoter Loops

2017 661 citations Abraham S. Weintraub, Alla A. Sigova et al. Cell profile →
Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

2014 639 citations Denes Hnisz, Brian J. Abraham et al. Cell profile →
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

2014 538 citations Marc R. Mansour, Brian J. Abraham et al. Science profile →
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

2019 455 citations Yang Guo, Alessandra Dall’Agnese et al. Nature profile →
CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

2014 451 citations Edmond Chipumuro, Eugenio Marco et al. Cell profile →
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

2016 394 citations Brian J. Abraham, Richard A. Young et al. Nature profile →
CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

2015 347 citations Yubao Wang, Tinghu Zhang et al. Cell profile →

Peers

Countries citing papers authored by Brian J. Abraham

Since Specialization

Citations

This map shows the geographic impact of Brian J. Abraham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian J. Abraham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian J. Abraham more than expected).

Fields of papers citing papers by Brian J. Abraham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian J. Abraham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian J. Abraham. The network helps show where Brian J. Abraham may publish in the future.

Co-authorship network of co-authors of Brian J. Abraham

This figure shows the co-authorship network connecting the top 25 collaborators of Brian J. Abraham. A scholar is included among the top collaborators of Brian J. Abraham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian J. Abraham. Brian J. Abraham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Abstract 481: Investigating molecular glues as a new therapeutic approach to high-risk neuroblastoma 2023 ·Cancer Research ·Ian Delahunty,Gisele Nishiguchi,Yang Zhang,(unknown),Anand Mayasundari,Jun Qi,Brian J. Abraham,Anang A. Shelat,Zoran Ranković,Adam D. Durbin	1
2	Regulatory architecture of housekeeping genes is driven by promoter assemblies 2023 ·Cell Reports ·Marion Déjosez,Alessandra Dall’Agnese,Mahesh Ramamoorthy,Jesse M. Platt,(unknown),Megan S. Hogan,Ran Brosh,Abraham S. Weintraub,Denes Hnisz,Brian J. Abraham,Richard A. Young,Thomas P. Zwaka	23
3	MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation 2021 ·Cancers ·(unknown),Mark W. Zimmerman,Nina Weichert‐Leahey,(unknown),Belamy B. Cheung,Brian J. Abraham,Anneleen Beckers,Pieter‐Jan Volders,Bieke Decaesteker,Daniel R. Carter,(unknown),Katleen De Preter,Wouter Van Loocke,Glenn M. Marshall,Adam D. Durbin,Frank Speleman,Kaat Durinck	9
4	RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells 2020 ·Nature Cell Biology ·Cristina Santoriello,(unknown),Song Yang,Ryan A. Flynn,Telmo Henriques,Bilguujin Dorjsuren,(unknown),(unknown),(unknown),Maurizio Fazio,(unknown),(unknown),Isaac Adatto,Brian J. Abraham,Marian Kalocsay,Michael J. Jurynec,Yi Zhou,Karen Adelman,Eliezer Calo,Leonard I. Zon	34
5	ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry 2019 ·Nature Communications ·Lu Wang,Tze King Tan,Adam D. Durbin,Mark W. Zimmerman,Brian J. Abraham,Shi Hao Tan,Phuong Cao Thi Ngoc,Nina Weichert‐Leahey,Koshi Akahane,Lee N. Lawton,Jo Lynne Rokita,John M. Maris,Richard A. Young,A. Thomas Look,Takaomi Sanda	54
6	Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry 2018 ·Nature Genetics ·Adam D. Durbin,Mark W. Zimmerman,Neekesh V. Dharia,Brian J. Abraham,Amanda Balboni Iniguez,Nina Weichert‐Leahey,Shuning He,John M. Krill-Burger,David E. Root,Francisca Vázquez,Aviad Tsherniak,William C. Hahn,Todd R. Golub,Richard A. Young,A. Thomas Look,Kimberly Stegmaier	145
7	c-MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification 2018 ·PMC ·Mark W. Zimmerman,Yu Liu,Shuning He,Adam D. Durbin,Brian J. Abraham,John M. Easton,Ying Shao,Beisi Xu,Shizhen Zhu,Xiaoling Zhang,Zhaodong Li,Nina Weichert‐Leahey,Richard A. Young,Jinghui Zhang,A. Thomas Look	2
8	MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification 2017 ·Cancer Discovery ·Mark W. Zimmerman,Yu Liu,Shuning He,Adam D. Durbin,Brian J. Abraham,John Easton,Ying Shao,Beisi Xu,Shizhen Zhu,Xiaoling Zhang,Zhaodong Li,Nina Weichert‐Leahey,Richard A. Young,Jinghui Zhang,A. Thomas Look	147
9	The long noncoding RNA Wisper controls cardiac fibrosis and remodeling 2017 ·Science Translational Medicine ·Rudi Micheletti,Isabelle Plaisance,Brian J. Abraham,Alexandre Sarre,(unknown),Michael Alexanian,(unknown),Damien Maison,Mohamed Nemir,Richard A. Young,Blanche Schroen,Arantxa González,Samir Ounzain,Thierry Pedrazzini	249
10	The long noncoding RNA Wisper controls cardiac fibrosis and remodeling 2017 ·DSpace@MIT (Massachusetts Institute of Technology) ·Rudi Micheletti,Isabelle Plaisance,Brian J. Abraham,Alexandre Sarre,(unknown),Michael Alexanian,(unknown),Damien Maison,Mohamed Nemir,Blanche Schroen,Arantxa González,Samir Ounzain,Thierry Pedrazzini,Richard A. Young	24
11	A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer 2017 ·Nature ·Paola Betancur,Brian J. Abraham,Ying Ying Yiu,Stephen B. Willingham,(unknown),Mark A. Zarnegar,Angera H. Kuo,Kelly M. McKenna,Yoko Kojima,Nicholas J. Leeper,Po Y. Ho,Phung Gip,Tomek Swigut,Richard I. Sherwood,Michael F. Clarke,George Somlo,Richard A. Young,Irving L. Weissman	1
12	Models of human core transcriptional regulatory circuitries 2016 ·Genome Research ·Violaine Saint‐André,Alexander Federation,Charles Y. Lin,Brian J. Abraham,Jessica Reddy,Tong Ihn Lee,James E. Bradner,Richard A. Young	169
13	Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions 2015 ·Proceedings of the National Academy of Sciences ·Ji Xiong,Daniel Benjamin Dadon,Brian J. Abraham,Tong Ihn Lee,Rudolf Jaenisch,James E. Bradner,Richard A. Young	110
14	Transcription factor trapping by RNA in gene regulatory elements 2015 ·Science ·Alla A. Sigova,Brian J. Abraham,Ji Xiong,Benoit Molinié,Nancy M. Hannett,Yang Guo,Mohini Jangi,Cosmas Giallourakis,Phillip A. Sharp,Richard A. Young	361
15	Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers 2015 ·DSpace@MIT (Massachusetts Institute of Technology) ·Denes Hnisz,Jurian Schuijers,Charles Y. Lin,Brian J. Abraham,Tong Ihn Lee,James E. Bradner,Abraham S. Weintraub,Richard A. Young	139
16	CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancerbreakdown → 2015 ·Cell ·Yubao Wang,Tinghu Zhang,Nicholas Kwiatkowski,Brian J. Abraham,Tong Ihn Lee,Shaozhen Xie,Haluk Yuzugullu,Thanh Von,Heyuan Li,Ziao Lin,Daniel G. Stover,Elgene Lim,Zhigang C. Wang,J. Dirk Iglehart,Richard A. Young,Nathanael S. Gray,Jean J. Zhao	347
17	An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic elementbreakdown → 2014 ·Science ·Marc R. Mansour,Brian J. Abraham,Lars Anders,Alla Berezovskaya,Alejandro Gutiérrez,Adam D. Durbin,Julia Etchin,Lee N. Lawton,Stephen E. Sallan,Lewis B. Silverman,Mignon L. Loh,Stephen P. Hunger,Takaomi Sanda,Richard A. Young,A. Thomas Look	538
18	CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer 2014 ·DSpace@MIT (Massachusetts Institute of Technology) ·Edmond Chipumuro,Eugenio Marco,Camilla L. Christensen,Tinghu Zhang,Clark M. Hatheway,Bandana Sharma,Caleb M. Yeung,Abigail Altabef,Antonio R. Pérez‐Atayde,Kwok‐Kin Wong,Guo‐Cheng Yuan,Nathanael S. Gray,Rani E. George,(unknown),Brian J. Abraham,Richard A. Young	1
19	CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancerbreakdown → 2014 ·Cell ·Edmond Chipumuro,Eugenio Marco,Camilla L. Christensen,Nicholas Kwiatkowski,Tinghu Zhang,Clark M. Hatheway,Brian J. Abraham,Bandana Sharma,Caleb M. Yeung,Abigail Altabef,Antonio R. Pérez‐Atayde,Kwok‐Kin Wong,Guo‐Cheng Yuan,Nathanael S. Gray,Richard A. Young,Rani E. George	451
20	Novel Mechanism of Positive versus Negative Regulation by Thyroid Hormone Receptor β1 (TRβ1) Identified by Genome-wide Profiling of Binding Sites in Mouse Liver 2013 ·Journal of Biological Chemistry ·Preeti Ramadoss,Brian J. Abraham,Linus Tsai,Yiming Zhou,Ricardo H. Costa‐e‐Sousa,(unknown),Martin Bilban,Keji Zhao,Anthony N. Hollenberg	83

About Brian J. Abraham

Brian J. Abraham is a scholar working on Neurology, Molecular Biology and Immunology, having authored 54 papers that have together received 13.2k indexed citations. Recurring topics across this work include Genomics and Chromatin Dynamics (22 papers), Protein Degradation and Inhibitors (17 papers) and Neuroblastoma Research and Treatments (15 papers). The work is most often cited by research in Molecular Biology (11.3k citations), Cancer Research (1.8k citations) and Immunology (1.3k citations). Brian J. Abraham has collaborated with scholars based in United States, China and United Kingdom. Frequent co-authors include Denes Hnisz, Richard A. Young, Tong Ihn Lee, Richard A. Young, Alla A. Sigova, Charles Y. Lin, Violaine Saint‐André, David A. Orlando, Peter B. Rahl and Ashley Lau. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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