R. Foti

2.0k citations

51 papers · 1.3k indexed · h-index 21

Impact in

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Toxicology top 2%

Papers in

Pharmacology 28
- Pharmacogenetics and Drug Metabolism 28
Biochemistry 5
- Eicosanoids and Hypertension Pharmacology 4

Co-authors: Jan L. Wahlstrom Michael B. Fisher Larry C. Wienkers Dan A. Rock Deepak Dalvie Timothy J. Strelevitz Josh T. Pearson Nina Isoherranen
Journals: Drug Metabolism and Disposition (20 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Molecular Pharmacology (3 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)Cancer Research (2 papers)
Partner nations: United States Switzerland France

In The Last Decade

R. Foti

49 papers receiving 1.3k citations

Peers

Countries citing papers authored by R. Foti

Since Specialization

Citations

This map shows the geographic impact of R. Foti's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. Foti with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. Foti more than expected).

Fields of papers citing papers by R. Foti

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. Foti. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. Foti. The network helps show where R. Foti may publish in the future.

Co-authors

The 25 scholars most cited alongside R. Foti, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with R. Foti Line = papers co-authored together R. Foti links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Activation of Hepatocyte Growth Factor/MET Signaling as a Mechanism of Acquired Resistance to a Novel YAP1/TEAD Small Molecule Inhibitor Molecular Cancer Therapeutics ·Casey J. Moure, Brandon Vara, Mangeng Cheng, Jeremiah Conway, Eric S. Muise, Giovanna Caputo Almeida Ferreira, Cristina Mucciolli, Dan Su, 祝锋, Yong Man Ro, Charles S. Yeung, Iqra Arzoo, My Sam Mansueto, 泰之山田, Mark Buchanan, R. Foti, Erin F. DiMauro, Brian J. Long, D Badowski-Zyla, Abed Sinno	2024	5
2	Utility of physiologically based pharmacokinetic modeling in predicting and characterizing clinical drug interactions Drug Metabolism and Disposition ·R. Foti	2024	13
3	Cytochrome P450 and Other Drug-Metabolizing Enzymes As Therapeutic Targets Drug Metabolism and Disposition ·R. Foti	2023	13
4	Discovery of pyridyl urea sulfonamide inhibitors of NaV1.7 Bioorganic & Medicinal Chemistry Letters ·Ferry Roni Wijaya Simanjuntak, Lavita Sarma, Benjamin C. Milgram, R. Foti, Thomas Kornecook, Joseph Ligutti, Bryan D. Moyer, Mariana Zechin Rosauro, Beth D. Youngblood, Violeta Yu, Roman Shimanovich, Alessandro A. Boezio, Matthew M. Weiss	2022	1
5	Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities Drug Metabolism and Disposition ·Brooke M. Rock, R. Foti	2019	17
6	Abstract 4484: Discovery and in vitro characterization of AMG 510–a potent and selective covalent small-molecule inhibitor of KRAS^G12C Anne Y. Saiki, Kevin Gaida, Karen Rex, Pragathi Achanta, Tisha San Miguel, Neelima Koppada, Dhanashri Bagal, Brian A. Lanman, R. Foti, John D. McCarter, Laurie P. Volak, Jude Canon, Victor J. Cee, Z P Krushinskaia	2019	1
7	1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of NaV1.7 inhibition Bioorganic & Medicinal Chemistry Letters ·Alessandro A. Boezio, Kristin L. Andrews, Е.В. Шеин, Margaret Y. Chu‐Moyer, H Roderig, Erin F. DiMauro, R. Foti, Robert T. Fremeau, Hua Gao, Stephanie Geuns-Meyer, Russell F. Graceffa, Hakan Günaydin, Hongbing Huang, Daniel S. La, Joseph Ligutti, Bryan D. Moyer, Emily A. Peterson, Violeta Yu, Matthew M. Weiss	2018	8
8	Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1 Journal of Pharmacology and Experimental Therapeutics ·R. Foti, Nina Isoherranen, Alex Zelter, Leslie J. Dickmann, Doğan Atılgan, Philippe Diaz, Dominique Douguet	2016	13
9	Cytochrome P450 and Non–Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics Drug Metabolism and Disposition ·R. Foti, Deepak Dalvie	2016	88
10	Characterization of the Active Site Properties of CYP4F12 Drug Metabolism and Disposition ·John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers, R. Foti	2014	16
11	Evaluation of UGT protein interactions in human hepatocytes: Effect of siRNA down regulation of UGT1A9 and UGT2B7 on propofol glucuronidation in human hepatocytes Archives of Biochemistry and Biophysics ·Naufal Hanif Nur Muhana, Leslie J. Dickmann, 光宮部, Robert H. Tukey, Larry C. Wienkers, R. Foti	2013	12
12	Predicting the Drug Interaction Potential of AMG 853, a Dual Antagonist of the D-Prostanoid and Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cells Receptors Drug Metabolism and Disposition ·R. Foti, Josh T. Pearson, Alain Audry, Julie Zalikowski, Marina Hanawa, M. Ingvesson, John A. Davis, Christopher Banfield, Maurice G. Emery, Dan A. Rock, Jan L. Wahlstrom, Larry C. Wienkers, Benny Amore	2012	2
13	Prediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent Inhibition Drug Metabolism and Disposition ·Brooke M. VandenBrink, R. Foti, Dan A. Rock, Larry C. Wienkers, Jan L. Wahlstrom	2011	62
14	Mechanism-Based Inactivation of Cytochrome P450 3A4 by Mibefradil through Heme Destruction Drug Metabolism and Disposition ·R. Foti, Dan A. Rock, Josh T. Pearson, Jan L. Wahlstrom, Larry C. Wienkers	2011	34
15	Selection of Alternative CYP3A4 Probe Substrates for Clinical Drug Interaction Studies Using In Vitro Data and In Vivo Simulation Drug Metabolism and Disposition ·R. Foti, Dan A. Rock, Larry C. Wienkers, Jan L. Wahlstrom	2010	103
16	The role of dietary supplements in cytochrome P450-mediated druginteractions Boletin Latinoamericano y del Caribe de plantas Medicinales y Aromaticas ·R. Foti, Jan L. Wahlstrom	2008	15
17	A streamlined method to predict hepatic clearance using human liver microsomes in the presence of human plasma Journal of Pharmacological and Toxicological Methods ·Nabin Uprety, R. Foti, Michael B. Fisher	2005	18
18	Assessment of UDP-glucuronosyltransferase catalyzed formation of ethyl glucuronide in human liver microsomes and recombinant UGTs Forensic Science International ·R. Foti, Michael B. Fisher	2005	108
19	ALTERED AZT (3′-AZIDO-3′-DEOXYTHYMIDINE) GLUCURONIDATION KINETICS IN LIVER MICROSOMES AS AN EXPLANATION FOR UNDERPREDICTION OF IN VIVO CLEARANCE: COMPARISON TO HEPATOCYTES AND EFFECT OF INCUBATION ENVIRONMENT Drug Metabolism and Disposition ·Susana Albelda, R. Foti, Timothy J. Strelevitz, Michael B. Fisher	2005	52
20	IMPACT OF INCUBATION CONDITIONS ON BUFURALOL HUMAN CLEARANCE PREDICTIONS: ENZYME LABILITY AND NONSPECIFIC BINDING Drug Metabolism and Disposition ·R. Foti, Michael B. Fisher	2004	25

About R. Foti

R. Foti is a scholar working on Pharmacology, Biochemistry, Biochemistry, Oncology and Computational Theory and Mathematics, having authored 51 papers that have together received 1.3k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (28 papers), Drug Transport and Resistance Mechanisms (13 papers), Computational Drug Discovery Methods (8 papers), Pharmacological Effects and Toxicity Studies (5 papers), Analytical Chemistry and Chromatography (4 papers), Eicosanoids and Hypertension Pharmacology (4 papers), Retinoids in leukemia and cellular processes (4 papers) and Ubiquitin and proteasome pathways (4 papers). The work is most often cited by research in Pharmacology (680 citations), Toxicology (80 citations), Oncology (373 citations), Biochemistry (98 citations) and Computational Theory and Mathematics (146 citations). R. Foti has collaborated with scholars based in United States, Switzerland and France. Frequent co-authors include Jan L. Wahlstrom, Michael B. Fisher, Larry C. Wienkers, Dan A. Rock, Deepak Dalvie, Timothy J. Strelevitz, Josh T. Pearson, Nina Isoherranen, Brooke M. VandenBrink and Leslie J. Dickmann. Their work appears in journals such as Drug Metabolism and Disposition, Bioorganic & Medicinal Chemistry Letters, Molecular Pharmacology, Journal of Pharmacology and Experimental Therapeutics and Cancer Research.

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