Andrew S. Tasker

2.8k citations

45 papers · 1.4k indexed · h-index 20

Organic Chemistry top 5%
- Synthesis and biological activity 5
Molecular Biology
- Protein Kinase Regulation and GTPase Signaling 6
- Melanoma and MAPK Pathways 5
- PI3K/AKT/mTOR signaling in cancer 4
- Receptor Mechanisms and Signaling 4
Biochemistry top 10%
Oncology
Cancer Research
Physiology
- Nitric Oxide and Endothelin Effects 8
Cardiology and Cardiovascular Medicine
- Renin-Angiotensin System Studies 5
Pathology and Forensic Medicine
- Cancer Mechanisms and Therapy 4

Co-authors: Ryan P. Wurz Terry J. Opgenorth William J. Chiou Bryan K. Sorensen Thomas W von Geldern Douglas B. Dixon Martin Winn Robert W. Steel
Cited by: Organic Chemistry Molecular Biology Biochemistry
Journals: Bioorganic & Medicinal Chemistry Letters (11 papers)Journal of Medicinal Chemistry (9 papers)ACS Medicinal Chemistry Letters (2 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Andrew S. Tasker

44 papers receiving 1.3k citations

Peers

Countries citing papers authored by Andrew S. Tasker

Since Specialization

Citations

This map shows the geographic impact of Andrew S. Tasker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew S. Tasker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew S. Tasker more than expected).

Fields of papers citing papers by Andrew S. Tasker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew S. Tasker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew S. Tasker. The network helps show where Andrew S. Tasker may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Andrew S. Tasker, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Andrew S. Tasker Line = papers co-authored together Andrew S. Tasker links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Panitumumab EGFR Complex Reveals a Binding Mechanism That Overcomes Cetuximab Induced Resistance PLoS ONE ·E. Allen Sickmier,Robert J. Kurzeja,Klaus Michelsen,Rana Choukri,Evelyn Yang,Andrew S. Tasker	2016	55
2	Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability ACS Medicinal Chemistry Letters ·Paul E. Harrington,Kaustav Biswas,David J. Malwitz,Andrew S. Tasker,Christopher Mohr,Kristin L. Andrews,たまか小川,Richard Kendall,Holger Beckmann,Peter Jaeckel,Nannan Jiang,Jennifer R. Allen,J. Russell Lipford	2014	74
3	The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Huiling Wang,Victor J. Cee,Jordan J. Kerns,Brian A. Lanman,Anthony B. Reed,Bin Wu,廖永堃 Yung-Kun Liao,J. Russell Lipford,Christine Sastri,P. Bourée,Kristin L. Andrews,Xin Huang,Matthew R. Lee,Christopher Mohr,Yang Xu,Yihong Zhou,Andrew S. Tasker	2014	27
4	Phosphoinositide-3-kinase inhibitors: Evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511 Bioorganic & Medicinal Chemistry Letters ·Brian A. Lanman,Anthony B. Reed,Victor J. Cee,Fang‐Tsao Hong,Liping H. Pettus,Ryan P. Wurz,Kristin L. Andrews,Jian Jiang,John D. McCarter,Erin L. Mullady,Tisha San Miguel,Raju Subramanian,Ling Wang,Douglas A. Whittington,Tian Wu,Leeanne Zalameda,Anh Cơ Trịnh,Andrew S. Tasker,Paul E. Hughes,Mark H. Norman	2014	3
5	TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation Molecular Cell ·Yi-Hung Ou,Michael J. Torres,Rosalyn Ram,Étienne Formstecher,Christina L. Roland,Tzuling Cheng,Rolf A. Brekken,Ryan P. Wurz,Andrew S. Tasker,Daniel L. M C Fadden,Seng-Lai Tan,Michael A. White	2011	174
6	Identification of triazolopyridazinones as potent p38α inhibitors Bioorganic & Medicinal Chemistry Letters ·Brad Herberich,Ya long Zhu,Ryan P. Wurz,Liping H. Pettus,Cristian Camilo Rivera Romero,Qiurong Liu,J. C. Barral,Christiaan J. M. Saris,Lu Min Wong,Samer Chmait,Matthew R. Lee,Christopher Mohr,Faye Hsieh,Andrew S. Tasker	2011	3
7	Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase^⊥⊥ Atomic coordinates and structure factors for crystal structure of compound3dwith p38α can be accessed using PDB code 3LHJ. Journal of Medicinal Chemistry ·Liping H. Pettus,Ryan P. Wurz,Shimin Xu,Brad Herberich,J. C. Barral,Qiurong Liu,Helen J. McBride,Sven Laqua,Matthew Plant,Christiaan J. M. Saris,Cristian Camilo Rivera Romero,Lu Min Wong,Samer Chmait,Matthew R. Lee,Christopher Mohr,Faye Hsieh,Andrew S. Tasker	2010	28
8	2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics Bioorganic & Medicinal Chemistry Letters ·Qingping Zeng,Matthew P. Bourbeau,Wenya Pi,Jae Eun Oh,Holger Monenschein,Bàrbara Monjo Pons,Matthew R. Lee,Shiwen Zhang,Julie A. Lofgren,Daniel J. Freeman,Chun Li,Rusvel J. Gómez B.,Xin Huang,Douglas W. Hoffman,Harvey Yamane,Andrew S. Tasker,Celia Dominguez,Vellarkad N. Viswanadhan,Randall W. Hungate,Xiaoling Zhang	2010	15
9	Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors Journal of Experimental & Clinical Cancer Research ·Sean Caenepeel,Lisa Renshaw-Gegg,Rafik Khan,Tammy L. Bush,L L Vasil'eva,Todd Juan,Raffi Manoukian,Andrew S. Tasker,Anthony Polverino,Paul E. Hughes	2010	15
10	Part 1: Structure–Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase Bioorganic & Medicinal Chemistry Letters ·Ryan P. Wurz,Liping H. Pettus,Shimin Xu,J. C. Barral,Cristian Camilo Rivera Romero,Matthew Plant,Kent Miner,Helen J. McBride,Lu Min Wong,Christiaan J. M. Saris,Matthew R. Lee,Samer Chmait,Christopher Mohr,Faye Hsieh,Andrew S. Tasker	2009	17
11	Discovery of amido-benzisoxazoles as potent c-Kit inhibitors Bioorganic & Medicinal Chemistry Letters ·Roxanne K. Kunz,Bipin J. Malaviya,D.E. Rybchakov,Dawei Zhang,Andrew S. Tasker,Roland W. Bürli,Randall W. Hungate,Violeta Yu,M. Karamouzian,Douglas A. Whittington,Kristin L. Meagher,Matthew Plant,Yanyan Tudor,Michael Schrag,Yang Xu,Gordon Ng,Essa Hu	2008	10
12	c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations Journal of Biological Chemistry ·Steven F. Bellon,Paula Kaplan‐Lefko,Yajing Yang,Yihong Zhang,Jodi Moriguchi,Karen Rex,Carol W. Johnson,Paul Rose,Alexander Long,Anne O’Connor,Yan Gu,Angela Coxon,Tae‐Seong Kim,Andrew S. Tasker,Teresa L. Burgess,Isabelle Dussault	2007	113
13	AMG 706 induces the rapid destruction of tumor microvessels in nude mice Cancer Research ·Stephen A. Kaufman,Charlie Starnes,Angela Coxon,Vinod F. Patel,Andrew S. Tasker,Daniel L. M C Fadden,Rick A. Kendall,Robert Radinsky,Russell C. Cattley	2006	2
14	Non-Covalent Cathepsin K Inhibitors for the Treatment of Osteoporosis Current Topics in Medicinal Chemistry ·Tae‐Seong Kim,Andrew S. Tasker	2006	16
15	(4-Piperidinylphenyl)aminoethyl amides as a novel class of non-covalent cathepsin K inhibitors Bioorganic & Medicinal Chemistry Letters ·Tae‐Seong Kim,Azam Shafaei,Abrão José Melham,Benjamin R. Cavarra,Christopher M. Tegley,Xianghong Wang,Teresa L. Burgess,Yixin Qian,Sandra L. Ross,Philip Tagari,Chih-Wei Lin,Carol A. Mayeda,Ebinezer Israel,Steven R. Jordan,Christopher Mohr,Janet Cheetham,Vellarkad N. Viswanadhan,Andrew S. Tasker	2003	6
16	Domoic acid neurotoxicity in hippocampal slice cultures Amino Acids ·Birthe Jakobsen,Andrew S. Tasker,Jens Zimmer	2002	19
17	Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity Bioorganic & Medicinal Chemistry ·Steven A. Boyd,Robert A. Mantei,Andrew S. Tasker,Gang Liu,Bryan K. Sorensen,Kenneth J. Henry,Thomas W von Geldern,Martin Winn,Jinshyun R. Wu‐Wong,William J. Chiou,Douglas B. Dixon,Charles W. Hutchins,Kennan C. Marsh,Bach Nguyen,Terry J. Opgenorth	1999	10
18	[3H]A-81988, a potent, selective, competitive antagonist radioligand for angiotensin AT1 receptors European Journal of Pharmacology Molecular Pharmacology ·Radhesh Hedge,Bruce W. Surber,Moon Sang-Ryong,Samuel Thomas,Andrew S. Tasker,Bryan K. Sorensen,Cifuentes Yépez,T. J. Opgenorth,Daniel J. Kerkman,John F. DeBernardis	1994	3
19	Characterization of two endothelin converting enzymes and their preference for big endothelin-1 and -2 as substrates Life Sciences ·William J. Chiou,Kazumi Shiosaki,Andrew S. Tasker,Jinshyun R. Wu‐Wong	1994	5
20	Potent and selective inhibitors of an aspartyl protease-like endothelin converting enzyme identified in rat lung Journal of Medicinal Chemistry ·Kazumi Shiosaki,Andrew S. Tasker,Gerard M. Sullivan,Bryan K. Sorensen,Thomas W von Geldern,Jinshyun R. Wu‐Wong,聡一朗河瀬,Terry J. Opgenorth	1993	12

About Andrew S. Tasker

Andrew S. Tasker is a scholar working on Biochemistry, Biophysics and Organic Chemistry, having authored 45 papers that have together received 1.4k indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (8 papers), Protein Kinase Regulation and GTPase Signaling (6 papers), Synthesis and biological activity (5 papers), Melanoma and MAPK Pathways (5 papers), Renin-Angiotensin System Studies (5 papers), PI3K/AKT/mTOR signaling in cancer (4 papers), Cancer Mechanisms and Therapy (4 papers) and Receptor Mechanisms and Signaling (4 papers). The work is most often cited by research in Organic Chemistry (482 citations), Molecular Biology (681 citations) and Biochemistry (65 citations). Andrew S. Tasker has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Ryan P. Wurz, Terry J. Opgenorth, William J. Chiou, Bryan K. Sorensen, Thomas W von Geldern, Douglas B. Dixon, Martin Winn, Robert W. Steel, Victor J. Cee and Tzuling Cheng. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Tetrahedron Letters and Cancer Research.

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