Essa Hu

1.2k total citations · 1 hit paper
21 papers, 916 citations indexed

About

Essa Hu is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Essa Hu has authored 21 papers receiving a total of 916 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 11 papers in Organic Chemistry and 6 papers in Pharmacology. Recurrent topics in Essa Hu's work include Phosphodiesterase function and regulation (8 papers), Cholinesterase and Neurodegenerative Diseases (6 papers) and Receptor Mechanisms and Signaling (5 papers). Essa Hu is often cited by papers focused on Phosphodiesterase function and regulation (8 papers), Cholinesterase and Neurodegenerative Diseases (6 papers) and Receptor Mechanisms and Signaling (5 papers). Essa Hu collaborates with scholars based in United States, Japan and United Kingdom. Essa Hu's co-authors include Daniel R. Sidler, Ulf‐H. Dolling, David A. Evans, Georg Jaeschke, Jason D. Burch, Jason S. Tedrow, James Treanor, Kristin L. Andrews, Roxanne K. Kunz and Samer Chmait and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

In The Last Decade

Essa Hu

21 papers receiving 893 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Unprecedented Catalytic Three Component One-Pot Condensation Reaction: An Efficient Synthesis of 5-Alkoxycarbonyl- 4-aryl-3,4-dihydropyrimidin-2(1H)-ones

1998 450 citations Essa Hu, Daniel R. Sidler et al. The Journal of Organic Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Essa Hu United States	13	779	241	180	53	33	21	916
Paul C. Fritch United States	9	564 0.7×	349 1.4×	122 0.7×	99 1.9×	26 0.8×	12	692
Tatsuo Tsuri Japan	13	403 0.5×	164 0.7×	165 0.9×	43 0.8×	27 0.8×	16	544
Roxanne K. Kunz United States	10	580 0.7×	162 0.7×	96 0.5×	31 0.6×	64 1.9×	13	662
Hemaka A. Rajapakse United States	13	434 0.6×	153 0.6×	104 0.6×	124 2.3×	41 1.2×	21	633
Suk Youn Kang South Korea	14	399 0.5×	139 0.6×	95 0.5×	50 0.9×	41 1.2×	21	527
Paul E. Harrington United States	18	896 1.2×	363 1.5×	141 0.8×	94 1.8×	101 3.1×	31	1.2k
David J. Madar United States	13	427 0.5×	255 1.1×	70 0.4×	42 0.8×	23 0.7×	20	639
Robert M. Rzasa United States	12	326 0.4×	149 0.6×	73 0.4×	54 1.0×	25 0.8×	16	499
Hiromi Oshiumi Japan	6	450 0.6×	248 1.0×	127 0.7×	123 2.3×	27 0.8×	8	570
Garry Fenton United Kingdom	14	378 0.5×	192 0.8×	95 0.5×	69 1.3×	42 1.3×	21	512

Countries citing papers authored by Essa Hu

Since Specialization

Citations

This map shows the geographic impact of Essa Hu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Essa Hu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Essa Hu more than expected).

Fields of papers citing papers by Essa Hu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Essa Hu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Essa Hu. The network helps show where Essa Hu may publish in the future.

Co-authorship network of co-authors of Essa Hu

This figure shows the co-authorship network connecting the top 25 collaborators of Essa Hu. A scholar is included among the top collaborators of Essa Hu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Essa Hu. Essa Hu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Hu, Essa, Fang‐Tsao Hong, Derek E. Piper, et al.. (2021). Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model. Journal of Medicinal Chemistry. 64(6). 3427–3438. 6 indexed citations

Hu, Essa, Ning Chen, Roxanne K. Kunz, et al.. (2016). Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical Studies. ACS Medicinal Chemistry Letters. 7(7). 719–723. 4 indexed citations

Hwang, Dah‐Ren, Essa Hu, Jennifer R. Allen, et al.. (2015). Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18F]AMG 580 in non-human primates. Nuclear Medicine and Biology. 42(8). 654–663. 9 indexed citations

Hwang, Dah‐Ren, Essa Hu, John Castrillon, et al.. (2014). Initial characterization of a PDE10A selective positron emission tomography tracer [11C]AMG 7980 in non-human primates. Nuclear Medicine and Biology. 41(4). 343–349. 19 indexed citations

Hu, Essa, Kristin L. Andrews, Samer Chmait, et al.. (2014). Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). ACS Medicinal Chemistry Letters. 5(6). 700–705. 18 indexed citations

Hu, Essa, Roxanne K. Kunz, Ning Chen, et al.. (2013). Design, Optimization, and Biological Evaluation of Novel Keto-Benzimidazoles as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). Journal of Medicinal Chemistry. 56(21). 8781–8792. 33 indexed citations

Hu, Essa, Roxanne K. Kunz, Ning Chen, et al.. (2012). Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(6). 2262–2265. 41 indexed citations

Hu, Essa, Roxanne K. Kunz, Kristin L. Andrews, et al.. (2012). Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3). Bioorganic & Medicinal Chemistry Letters. 22(22). 6938–6942. 10 indexed citations

Rzasa, Robert M., Essa Hu, Ning Chen, et al.. (2012). Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux. Bioorganic & Medicinal Chemistry Letters. 22(24). 7371–7375. 21 indexed citations

10.

Evans, David A., Jason D. Burch, Essa Hu, & Georg Jaeschke. (2008). Enantioselective total synthesis of callipeltoside A: two approaches to the macrolactone fragment. Tetrahedron. 64(21). 4671–4699. 39 indexed citations

11.

Chen, Ning, Roland W. Bürli, Susana Neira, et al.. (2008). Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases. Bioorganic & Medicinal Chemistry Letters. 18(14). 4137–4141. 6 indexed citations

12.

Kunz, Roxanne K., Dawei Zhang, Andrew S. Tasker, et al.. (2008). Discovery of amido-benzisoxazoles as potent c-Kit inhibitors. Bioorganic & Medicinal Chemistry Letters. 18(18). 5115–5117. 10 indexed citations

13.

Li, Yiwei, Jun Liang, Tony Siu, et al.. (2008). Allosteric inhibitors of Akt1 and Akt2: Discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity. Bioorganic & Medicinal Chemistry Letters. 19(3). 834–836. 49 indexed citations

14.

Hu, Essa, Andrew S. Tasker, Ryan D. White, et al.. (2008). Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. Journal of Medicinal Chemistry. 51(11). 3065–3068. 37 indexed citations

15.

Evans, David A., Jason D. Burch, Essa Hu, & Georg Jaeschke. (2008). ChemInform Abstract: Enantioselective Total Synthesis of Callipeltoside A (I): Two Approaches to the Macrolactone Fragment.. ChemInform. 39(39). 2 indexed citations

16.

Hu, Essa, Peter Chua, Lida Tehrani, et al.. (2004). Pyrimidine methyl anilines: selective potentiators for the metabotropic glutamate 2 receptor. Bioorganic & Medicinal Chemistry Letters. 14(20). 5071–5074. 12 indexed citations

17.

Sidler, Daniel R., Nancy S. Barta, Wenjie Li, et al.. (2002). Efficient synthesis of the optically active dihydropyrimidinone of a potent α_1A- selective adrenoceptor antagonist. Canadian Journal of Chemistry. 80(6). 646–652. 17 indexed citations

18.

Evans, David A., Essa Hu, Jason D. Burch, & Georg Jaeschke. (2002). Enantioselective Total Synthesis of Callipeltoside A. Journal of the American Chemical Society. 124(20). 5654–5655. 74 indexed citations

19.

Evans, David A., Essa Hu, & Jason S. Tedrow. (2001). An Aldol-Based Approach to the Asymmetric Synthesis of l-Callipeltose, the Deoxyamino Sugar of l-Callipeltoside A. Organic Letters. 3(20). 3133–3136. 41 indexed citations

20.

Boumendjel, Ahcène, J. C. Roberts, Essa Hu, Peter V. Pallai, & Julius Rebek. (1996). Design and Asymmetric Synthesis of β-Strand Peptidomimetics. The Journal of Organic Chemistry. 61(13). 4434–4438. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact