Douglas A. Whittington

5.8k total citations
57 papers, 2.8k citations indexed

About

Douglas A. Whittington is a scholar working on Molecular Biology, Oncology and Inorganic Chemistry. According to data from OpenAlex, Douglas A. Whittington has authored 57 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 47 papers in Molecular Biology, 14 papers in Oncology and 11 papers in Inorganic Chemistry. Recurrent topics in Douglas A. Whittington's work include Metal-Catalyzed Oxygenation Mechanisms (11 papers), Microbial metabolism and enzyme function (7 papers) and PI3K/AKT/mTOR signaling in cancer (7 papers). Douglas A. Whittington is often cited by papers focused on Metal-Catalyzed Oxygenation Mechanisms (11 papers), Microbial metabolism and enzyme function (7 papers) and PI3K/AKT/mTOR signaling in cancer (7 papers). Douglas A. Whittington collaborates with scholars based in United States, Sweden and Netherlands. Douglas A. Whittington's co-authors include Stephen J. Lippard, David W. Christianson, Bernhard Spingler, Christin Frederick, Amy C. Rosenzweig, Richard A. Friesner, Barry D. Dunietz, Marek Urbanský, Robert M. Coates and Mitchell L. Wise and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Douglas A. Whittington

56 papers receiving 2.8k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Douglas A. Whittington United States 29 1.8k 768 679 467 409 57 2.8k
Mark A. Ator United States 37 1.8k 1.0× 602 0.8× 462 0.7× 772 1.7× 134 0.3× 91 3.1k
Stefan Lutz United States 31 4.1k 2.3× 721 0.9× 244 0.4× 433 0.9× 147 0.4× 92 5.9k
Chaojie Wang China 35 2.3k 1.3× 897 1.2× 156 0.2× 523 1.1× 368 0.9× 183 4.1k
Herman Schreuder Germany 32 1.7k 1.0× 337 0.4× 250 0.4× 213 0.5× 144 0.4× 81 3.1k
Carrie M. Wilmot United States 32 3.1k 1.7× 352 0.5× 947 1.4× 240 0.5× 127 0.3× 93 4.0k
Sagar D. Khare United States 30 3.3k 1.9× 743 1.0× 151 0.2× 372 0.8× 156 0.4× 70 4.7k
Rudi Fasan United States 46 3.3k 1.9× 3.9k 5.0× 1.6k 2.4× 417 0.9× 330 0.8× 115 6.7k
William M. Atkins United States 32 2.4k 1.3× 262 0.3× 257 0.4× 772 1.7× 129 0.3× 107 3.9k
Jasmine L. Gallaher United States 9 2.8k 1.6× 486 0.6× 171 0.3× 156 0.3× 114 0.3× 9 3.5k
Luigi Di Costanzo Italy 30 1.6k 0.9× 538 0.7× 240 0.4× 195 0.4× 256 0.6× 75 2.9k

Countries citing papers authored by Douglas A. Whittington

Since Specialization
Citations

This map shows the geographic impact of Douglas A. Whittington's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas A. Whittington with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas A. Whittington more than expected).

Fields of papers citing papers by Douglas A. Whittington

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas A. Whittington. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas A. Whittington. The network helps show where Douglas A. Whittington may publish in the future.

Co-authorship network of co-authors of Douglas A. Whittington

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas A. Whittington. A scholar is included among the top collaborators of Douglas A. Whittington based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas A. Whittington. Douglas A. Whittington is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cottrell, Kevin M., Kimberly J. Briggs, Alice Tsai, et al.. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry. 68(5). 5097–5119. 7 indexed citations
2.
Briggs, Kimberly J., Kevin M. Cottrell, Minjie Zhang, et al.. (2025). TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers. Translational Oncology. 52. 102264–102264. 6 indexed citations
3.
Lazarides, Katherine, Yi Yu, Shangtao Liu, et al.. (2025). CRISPR Screens Identify POLB as a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-Mutated Tumors. Molecular Cancer Therapeutics. 24(9). 1466–1479. 1 indexed citations
4.
Gurard‐Levin, Zachary A., Brian J. McMillan, Douglas A. Whittington, et al.. (2024). A duplexed high-throughput mass spectrometry assay for bifunctional POLB polymerase and lyase activity. SLAS TECHNOLOGY. 29(5). 100173–100173. 3 indexed citations
5.
Estes, Bram, Athena Sudom, Danyang Gong, et al.. (2021). Next generation Fc scaffold for multispecific antibodies. iScience. 24(12). 103447–103447. 9 indexed citations
6.
Frohn, Michael, Longbin Liu, Aaron C. Siegmund, et al.. (2020). The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement. Bioorganic & Medicinal Chemistry Letters. 30(14). 127240–127240. 4 indexed citations
7.
Stec, Markian M., Kristin L. Andrews, Yunxin Bo, et al.. (2015). The imidazo[1,2-a]pyridine ring system as a scaffold for potent dual phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitors. Bioorganic & Medicinal Chemistry Letters. 25(19). 4136–4142. 18 indexed citations
8.
Lanman, Brian A., Anthony B. Reed, Victor J. Cee, et al.. (2014). Phosphoinositide-3-kinase inhibitors: Evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511. Bioorganic & Medicinal Chemistry Letters. 24(24). 5630–5634. 3 indexed citations
9.
10.
Bryan, Marian C., Douglas A. Whittington, Elizabeth M. Doherty, et al.. (2012). Rapid Development of Piperidine Carboxamides as Potent and Selective Anaplastic Lymphoma Kinase Inhibitors. Journal of Medicinal Chemistry. 55(4). 1698–1705. 28 indexed citations
11.
Huang, Hongbing, Daniel S. La, Alan C. Cheng, et al.. (2012). Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer’s Disease. Journal of Medicinal Chemistry. 55(21). 9156–9169. 51 indexed citations
12.
Bode, Christiane, Alessandro A. Boezio, Brian K. Albrecht, et al.. (2012). Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(12). 4089–4093. 16 indexed citations
13.
Epstein, Linda F., Hao Chen, Renee Emkey, & Douglas A. Whittington. (2012). The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. Journal of Biological Chemistry. 287(44). 37447–37457. 37 indexed citations
14.
Kunz, Roxanne K., Dawei Zhang, Andrew S. Tasker, et al.. (2008). Discovery of amido-benzisoxazoles as potent c-Kit inhibitors. Bioorganic & Medicinal Chemistry Letters. 18(18). 5115–5117. 10 indexed citations
15.
Shin, Hyunshun, et al.. (2007). Amphipathic benzoic acid derivatives: Synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC. Bioorganic & Medicinal Chemistry. 15(7). 2617–2623. 25 indexed citations
16.
Hernick, Marcy, et al.. (2005). UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine Deacetylase Functions through a General Acid-Base Catalyst Pair Mechanism. Journal of Biological Chemistry. 280(17). 16969–16978. 51 indexed citations
17.
Whittington, Douglas A., Mitchell L. Wise, Marek Urbanský, et al.. (2002). Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase. Proceedings of the National Academy of Sciences. 99(24). 15375–15380. 273 indexed citations
18.
Spingler, Bernhard, Douglas A. Whittington, & Stephen J. Lippard. (2002). 2.4 Å Crystal Structure of an Oxaliplatin 1,2-d(GpG) Intrastrand Cross-Link in a DNA Dodecamer Duplex. Inorganic Chemistry. 42(2). 650–650. 2 indexed citations
19.
Gherman, Benjamin F., Barry D. Dunietz, Douglas A. Whittington, Stephen J. Lippard, & Richard A. Friesner. (2001). Activation of the C−H Bond of Methane by Intermediate Q of Methane Monooxygenase:  A Theoretical Study. Journal of the American Chemical Society. 123(16). 3836–3837. 101 indexed citations
20.
Whittington, Douglas A., Amy C. Rosenzweig, Christin Frederick, & Stephen J. Lippard. (2001). Xenon and Halogenated Alkanes Track Putative Substrate Binding Cavities in the Soluble Methane Monooxygenase Hydroxylase,. Biochemistry. 40(12). 3476–3482. 78 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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