Vincent B. Luscombe

571 total citations
30 papers, 342 citations indexed

About

Vincent B. Luscombe is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Computational Theory and Mathematics. According to data from OpenAlex, Vincent B. Luscombe has authored 30 papers receiving a total of 342 indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 15 papers in Cellular and Molecular Neuroscience and 6 papers in Computational Theory and Mathematics. Recurrent topics in Vincent B. Luscombe's work include Receptor Mechanisms and Signaling (23 papers), Neuroscience and Neuropharmacology Research (13 papers) and Pharmacological Receptor Mechanisms and Effects (12 papers). Vincent B. Luscombe is often cited by papers focused on Receptor Mechanisms and Signaling (23 papers), Neuroscience and Neuropharmacology Research (13 papers) and Pharmacological Receptor Mechanisms and Effects (12 papers). Vincent B. Luscombe collaborates with scholars based in United States, United Kingdom and Australia. Vincent B. Luscombe's co-authors include Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Darren W. Engers, Alice L. Rodriguez, Sichen Chang, Anna L. Blobaum, Hyekyung P. Cho, Angela J. Russell and Carole J. R. Bataille and has published in prestigious journals such as Journal of Medicinal Chemistry, British Journal of Pharmacology and European Journal of Pharmacology.

In The Last Decade

Vincent B. Luscombe

30 papers receiving 339 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Vincent B. Luscombe United States	12	253	180	76	39	18	30	342
Paola De Giorgio Italy	10	243 1.0×	180 1.0×	79 1.0×	25 0.6×	19 1.1×	13	355
Stephen L. Garland United Kingdom	10	323 1.3×	174 1.0×	104 1.4×	58 1.5×	29 1.6×	13	443
Jessica Sallander Sweden	9	238 0.9×	121 0.7×	48 0.6×	41 1.1×	17 0.9×	10	292
Giles A. Brown United Kingdom	13	241 1.0×	122 0.7×	173 2.3×	39 1.0×	26 1.4×	17	455
Ícaro A. Simon Denmark	6	221 0.9×	145 0.8×	40 0.5×	36 0.9×	8 0.4×	8	300
Manuela Jörg Australia	15	523 2.1×	245 1.4×	121 1.6×	66 1.7×	17 0.9×	36	667
Horst Dollinger Germany	7	207 0.8×	170 0.9×	72 0.9×	66 1.7×	56 3.1×	12	382
Christina N. Di Marco United States	15	358 1.4×	192 1.1×	149 2.0×	42 1.1×	20 1.1×	23	504
Lizi Xia Netherlands	9	335 1.3×	172 1.0×	57 0.8×	47 1.2×	16 0.9×	11	394
Niall M. Hamilton United Kingdom	13	240 0.9×	111 0.6×	143 1.9×	18 0.5×	46 2.6×	30	467

Countries citing papers authored by Vincent B. Luscombe

Since Specialization

Citations

This map shows the geographic impact of Vincent B. Luscombe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Vincent B. Luscombe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Vincent B. Luscombe more than expected).

Fields of papers citing papers by Vincent B. Luscombe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Vincent B. Luscombe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Vincent B. Luscombe. The network helps show where Vincent B. Luscombe may publish in the future.

Co-authorship network of co-authors of Vincent B. Luscombe

This figure shows the co-authorship network connecting the top 25 collaborators of Vincent B. Luscombe. A scholar is included among the top collaborators of Vincent B. Luscombe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Vincent B. Luscombe. Vincent B. Luscombe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Engers, Julie L., Sichen Chang, Vincent B. Luscombe, et al.. (2024). Discovery of VU6008677: A Structurally Distinct Tricyclic M₄ Positive Allosteric Modulator with Improved CYP450 Profile. ACS Medicinal Chemistry Letters. 15(8). 1358–1366. 2 indexed citations

Engers, Julie L., Sichen Chang, Vincent B. Luscombe, et al.. (2024). Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM). ACS Chemical Neuroscience. 1 indexed citations

Luscombe, Vincent B., et al.. (2023). Biased agonists of GPR84 and insights into biological control. British Journal of Pharmacology. 181(10). 1509–1523. 2 indexed citations

Luscombe, Vincent B., Luis Alberto Baena-López, Carole J. R. Bataille, Angela J. Russell, & David R. Greaves. (2023). Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84. European Journal of Pharmacology. 956. 175960–175960. 6 indexed citations

Spearing, Paul K., Hyekyung P. Cho, Vincent B. Luscombe, et al.. (2021). Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M1. Bioorganic & Medicinal Chemistry Letters. 47. 128193–128193. 3 indexed citations

Spearing, Paul K., Julie L. Engers, Alison R. Gregro, et al.. (2021). Discovery of structurally distinct tricyclic M4 positive allosteric modulator (PAM) chemotypes – Part 2. Bioorganic & Medicinal Chemistry Letters. 53. 128416–128416. 4 indexed citations

Luscombe, Vincent B., et al.. (2020). 20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?. DNA and Cell Biology. 39(11). 1926–1937. 40 indexed citations

Temple, Kayla J., Julie L. Engers, Alison R. Gregro, et al.. (2019). Discovery of a novel 3,4-dimethylcinnoline carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping. Bioorganic & Medicinal Chemistry Letters. 29(21). 126678–126678. 9 indexed citations

Temple, Kayla J., Julie L. Engers, Sichen Chang, et al.. (2019). Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M4 positive allosteric modulator (PAM) chemotype. Bioorganic & Medicinal Chemistry Letters. 30(3). 126812–126812. 4 indexed citations

10.

Temple, Kayla J., Julie L. Engers, Sichen Chang, et al.. (2019). Discovery of structurally distinct tricyclic M4 positive allosteric modulator (PAM) chemotypes. Bioorganic & Medicinal Chemistry Letters. 30(4). 126811–126811. 6 indexed citations

11.

Childress, Elizabeth S., Vincent B. Luscombe, Alice L. Rodriguez, et al.. (2019). Evaluation of Synthetic Cytochrome P₄₅₀-Mimetic Metalloporphyrins To Facilitate “Biomimetic” Biotransformation of a Series of mGlu₅ Allosteric Ligands. ACS Omega. 4(7). 12782–12789. 2 indexed citations

12.

Poslusney, Michael S., James M. Salovich, Michael R. Wood, et al.. (2018). Novel M4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands. Bioorganic & Medicinal Chemistry Letters. 29(3). 362–366. 3 indexed citations

13.

Bender, Aaron M., Rebecca L. Weiner, Vincent B. Luscombe, et al.. (2017). Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotype. Bioorganic & Medicinal Chemistry Letters. 27(11). 2479–2483. 2 indexed citations

14.

Engers, Julie L., Sichen Chang, Xiaoyan Zhan, et al.. (2017). Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping. Bioorganic & Medicinal Chemistry Letters. 27(22). 4999–5001. 14 indexed citations

15.

Spearing, Paul K., Rebecca L. Weiner, Vincent B. Luscombe, et al.. (2017). Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core. Bioorganic & Medicinal Chemistry Letters. 27(18). 4274–4279. 6 indexed citations

16.

Tarr, James C., Michael R. Wood, Meredith J. Noetzel, et al.. (2017). Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides. Bioorganic & Medicinal Chemistry Letters. 27(23). 5179–5184. 11 indexed citations

17.

Bender, Aaron M., Rebecca L. Weiner, Vincent B. Luscombe, et al.. (2017). Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonists. Bioorganic & Medicinal Chemistry Letters. 27(15). 3576–3581. 9 indexed citations

18.

Abe, Masahito, Mabel Seto, Rocco G. Gogliotti, et al.. (2017). Discovery of VU6005649, a CNS Penetrant mGlu_7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines. ACS Medicinal Chemistry Letters. 8(10). 1110–1115. 28 indexed citations

19.

McGowan, Kevin, Paul K. Spearing, Branden J. Stansley, et al.. (2017). VU6010608, a Novel mGlu₇ NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides. ACS Medicinal Chemistry Letters. 8(12). 1326–1330. 20 indexed citations

20.

Wood, Michael R., Meredith J. Noetzel, Michael S. Poslusney, et al.. (2016). Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs. Bioorganic & Medicinal Chemistry Letters. 27(2). 171–175. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact