Patrick R. Gentry
About
Patrick R. Gentry is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Spectroscopy.
According to data from OpenAlex, Patrick R. Gentry has authored 32 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 20 papers in Cellular and Molecular Neuroscience and 6 papers in Spectroscopy. Recurrent topics in Patrick R. Gentry's work include Receptor Mechanisms and Signaling (27 papers), Neuroscience and Neuropharmacology Research (15 papers) and Neuropeptides and Animal Physiology (9 papers). Patrick R. Gentry is often cited by papers focused on Receptor Mechanisms and Signaling (27 papers), Neuroscience and Neuropharmacology Research (15 papers) and Neuropeptides and Animal Physiology (9 papers). Patrick R. Gentry collaborates with scholars based in United States, Australia and Denmark. Patrick R. Gentry's co-authors include Craig W. Lindsley, Thomas M. Bridges, P. Jeffrey Conn, Patrick M. Sexton, Arthur Christopoulos, Cody J. Wenthur, Thomas P. Mathews, Corey R. Hopkins, Colleen M. Niswender and R. Nathan Daniels and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.
In The Last Decade
Patrick R. Gentry
31 papers receiving 1.5k citations
Peers
Patrick R. Gentry
Bianca Plouffe Canada
Michael J. Karmilowicz United States
David L. Roman United States
Gina H. Lu United States
Harry Wadsworth United States
Tjeerd Barf Netherlands
A. Thomsen United States
Andreas Langer Germany
Roland Neuhaus Germany
Rosana I. Reis Brazil
Citations per year, relative to Patrick R. Gentry Patrick R. Gentry (= 1×)
peers
Bianca Plouffe
Countries citing papers authored by Patrick R. Gentry
Since
Specialization
Citations
This map shows the geographic impact of Patrick R. Gentry's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick R. Gentry with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick R. Gentry more than expected).
Fields of papers citing papers by Patrick R. Gentry
Since
Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences
This network shows the impact of papers produced by Patrick R. Gentry. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick R. Gentry. The network helps show where Patrick R. Gentry may publish in the future.
Co-authorship network of co-authors of Patrick R. Gentry
This figure shows the co-authorship network connecting the top 25 collaborators of Patrick R. Gentry. A scholar is included among the top collaborators of Patrick R. Gentry based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick R. Gentry. Patrick R. Gentry is excluded from the visualization to improve readability, since they are connected to all nodes in the network.
All Works
1.
Mobbs, Jesse I., Jinan Wang, Patrick R. Gentry, et al.. (2025). Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR. Nature Communications. 16(1). 7046–7046.
2.
Vuckovic, Ziva, Patrick R. Gentry, Kunio Hirata, et al.. (2019). Crystal structure of the M 5 muscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences. 116(51). 26001–26007.
3.
Palmer, Daniel, et al.. (2019). Identification of a novel scaffold for a small molecule GPR139 receptor agonist. Scientific Reports. 9(1). 3802–3802.
4.
Gentry, Patrick R., Patricia Rueda, Sandra den Hoedt, et al.. (2016). Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators. Molecular Pharmacology. 90(4). 427–436.
5.
Gogliotti, Rocco D., Darren W. Engers, Pedro M. García-Barrantes, et al.. (2016). Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. 26(12). 2915–2919.
6.
Gentry, Patrick R., Patrick M. Sexton, & Arthur Christopoulos. (2015). Novel Allosteric Modulators of G Protein-coupled Receptors. Journal of Biological Chemistry. 290(32). 19478–19488.
7.
Gentry, Patrick R., Masaya Kokubo, Thomas M. Bridges, et al.. (2014). Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)‐Selective M5‐Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe. ChemMedChem. 9(8). 1677–1682.
8.
Foster, Daniel J., Patrick R. Gentry, José E. Lizardi-Ortiz, et al.. (2014). M5Receptor Activation Produces Opposing Physiological Outcomes in Dopamine Neurons Depending on the Receptor's Location. Journal of Neuroscience. 34(9). 3253–3262.
9.
Gentry, Patrick R., Masaya Kokubo, Thomas M. Bridges, et al.. (2014). Development of a Highly Potent, Novel M5Positive Allosteric Modulator (PAM) Demonstrating CNS Exposure: 1-((1H-Indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380). Journal of Medicinal Chemistry. 57(18). 7804–7810.
10.
Gentry, Patrick R., Thomas M. Bridges, Atin Lamsal, et al.. (2013). Discovery of ML326: The first sub-micromolar, selective M5 PAM. Bioorganic & Medicinal Chemistry Letters. 23(10). 2996–3000.
11.
Gentry, Patrick R., Masaya Kokubo, Thomas M. Bridges, et al.. (2013). Discovery of the First M5-Selective and CNS Penetrant Negative Allosteric Modulator (NAM) of a Muscarinic Acetylcholine Receptor: (S)-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-one (ML375). Journal of Medicinal Chemistry. 56(22). 9351–9355.
12.
Poslusney, Michael S., Bruce J. Melancon, Patrick R. Gentry, et al.. (2013). Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: The continued optimization of an MLPCN probe molecule. Bioorganic & Medicinal Chemistry Letters. 23(6). 1860–1864.
13.
Melancon, Bruce J., Michael S. Poslusney, Patrick R. Gentry, et al.. (2012). Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: Continued optimization of an MLPCN probe molecule. Bioorganic & Medicinal Chemistry Letters. 23(2). 412–416.
14.
Bridges, Thomas M., J. Phillip Kennedy, Meredith J. Noetzel, et al.. (2010). Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAM. Bioorganic & Medicinal Chemistry Letters. 20(6). 1972–1975.
15.
Engers, Darren W., Patrick R. Gentry, Richard D. Williams, et al.. (2010). Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS). Bioorganic & Medicinal Chemistry Letters. 20(17). 5175–5178.
16.
Bridges, Thomas M., Joy E. Marlo, Colleen M. Niswender, et al.. (2009). Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy N -Benzyl Isatins. Journal of Medicinal Chemistry. 52(11). 3445–3448.
17.
Bridges, Thomas M., J. Phillip Kennedy, Hyekyung P. Cho, et al.. (2009). Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAM. Bioorganic & Medicinal Chemistry Letters. 20(2). 558–562.
18.
Williams, Richard D., Kari A. Johnson, Patrick R. Gentry, et al.. (2009). Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4). Bioorganic & Medicinal Chemistry Letters. 19(17). 4967–4970.
19.
Kennedy, J. Phillip, Thomas M. Bridges, Patrick R. Gentry, et al.. (2009). Synthesis and Structure–Activity Relationships of Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor. ChemMedChem. 4(10). 1600–1607.
20.
Brady, Ashley E., Carrie K. Jones, Thomas M. Bridges, et al.. (2008). Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats. Journal of Pharmacology and Experimental Therapeutics. 327(3). 941–953.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.
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