Patrick M. Sexton

30.6k citations

351 papers · 22.4k indexed · 6 hit papers · h-index 77

Cellular and Molecular Neuroscience top 0.02%
- Neuropeptides and Animal Physiology 211
- Neuroscience and Neuropharmacology Research 32
Molecular Biology top 0.1%
- Receptor Mechanisms and Signaling 281
- Protein Kinase Regulation and GTPase Signaling 23
- Signaling Pathways in Disease 21
Physiology top 0.1%
Endocrinology, Diabetes and Metabolism top 0.2%
- Diabetes Treatment and Management 53
Endocrine and Autonomic Systems top 0.5%
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 29
Surgery
- Pancreatic function and diabetes 22

Co-authors: Arthur Christopoulos Denise Wootten Katie Leach Céline Valant Lauren T. May Laurence J. Miller George Christopoulos J. Robert Lane
Cited by: Cellular and Molecular Neuroscience Molecular Biology Physiology
Journals: Molecular Pharmacology (44 papers)Journal of Biological Chemistry (26 papers)Biochemical Pharmacology (17 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

Patrick M. Sexton

347 papers receiving 22.0k citations

Hit Papers

6 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2018 Nature Reviews Molecular Cell Biology
2017 Nature
2016 Pharmacological Reviews
2013 Nature
2006 The Annual Review of Pharmacology and Toxicology
2006 Journal of Pharmacology and Experimental Therapeutics

Peers

Countries citing papers authored by Patrick M. Sexton

Since Specialization

Citations

This map shows the geographic impact of Patrick M. Sexton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick M. Sexton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick M. Sexton more than expected).

Fields of papers citing papers by Patrick M. Sexton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick M. Sexton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick M. Sexton. The network helps show where Patrick M. Sexton may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Patrick M. Sexton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick M. Sexton Line = papers co-authored together Patrick M. Sexton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors Nature Communications ·Jianjun Cao,Matthew J. Belousoff,Rachel M. Johnson,Peter Keov,Zamara Mariam,Giuseppe Deganutti,George Christopoulos,Caroline A. Hick,Steffen Reedtz‐Runge,Tine Glendorf,航成宮田,Kirsten Raun,Charles Bayly-Jones,Denise Wootten,Patrick M. Sexton	2025	3
2	Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3 Biochemistry ·Ai Tang,Xin Zhang,Fabian Bumbak,Erika Simón,Tracy M. Josephs,Michael G. Leeming,George Christopoulos,Hariprasad Venugopal,Maria M. Flocco,Patrick M. Sexton,Denise Wootten,Matthew J. Belousoff	2024	12
3	Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein Biochemistry ·Jianjun Cao,Matthew J. Belousoff,Radostin Danev,Arthur Christopoulos,Denise Wootten,Patrick M. Sexton	2024	4
4	Porous Silicon Microparticles Enable Sustained Release of GLP‐1R Agonist Peptides for the Treatment of Type 2 Diabetes Advanced Therapeutics ·Parham Sahandi Zangabad,Roshan B. Vasani,Ziqiu Tong,Dovile Anderson,David Rudd,Caroline A. Hick,Denise Wootten,Patrick M. Sexton,Li Yan,Lars Esser,Nicolas H. Voelcker	2024	3
5	Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR Nature Communications ·尚子佐々木,Vi Pham,Ziva Vuckovic,Alexander S. Powers,Jesse I. Mobbs,Fabien Bernard Roman Zablocki,Alisa Glukhova,Denise Wootten,Andrew B. Tobin,Patrick M. Sexton,Steven M. Paul,Christian C. Felder,Radostin Danev,Ron O. Dror,Arthur Christopoulos,Céline Valant,David M. Thal	2023	24
6	A structural basis for amylin receptor phenotype Science ·Jianjun Cao,Matthew J. Belousoff,Yi-Lynn Liang,Rachel M. Johnson,Tracy M. Josephs,Madeleine M. Fletcher,Arthur Christopoulos,Debbie L. Hay,Radostin Danev,Denise Wootten,Patrick M. Sexton	2022	53
7	Implications of ligand-receptor binding kinetics on GLP-1R signalling Biochemical Pharmacology ·Peishen Zhao,Tin T. Truong,Jon Merlin,Patrick M. Sexton,Denise Wootten	2022	15
8	Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation Nature Communications ·Giuseppe Deganutti,Yi-Lynn Liang,Xin Zhang,Maryam Khoshouei,Lachlan Clydesdale,Matthew J. Belousoff,Hariprasad Venugopal,Tin T. Truong,Alisa Glukhova,Andrew N. Keller,Karen J. Gregory,Katie Leach,Arthur Christopoulos,Radostin Danev,Christopher A. Reynolds,Peishen Zhao,Patrick M. Sexton,Denise Wootten	2022	49
9	Structure and dynamics of the CGRP receptor in apo and peptide-bound forms Science ·Tracy M. Josephs,Matthew J. Belousoff,Yi-Lynn Liang,Sarah Piper,Jianjun Cao,Daniel J. Garama,Katie Leach,Karen J. Gregory,Arthur Christopoulos,Debbie L. Hay,Radostin Danev,Denise Wootten,Patrick M. Sexton	2021	63
10	Cognitive behavioral markers of neurodevelopmental trajectories in rodents Translational Psychiatry ·Kwok Ho Christopher Choy,В.С. Шелудько,Cassandra Wannan,Liliana Laskaris,Hao Jiang,Warda Syeda,Patrick M. Sexton,Arthur Christopoulos,Christos Pantelis,Jess Nithianantharajah	2021	6
11	Development of Novel 4‐Arylpyridin‐2‐one and 6‐Arylpyrimidin‐4‐one Positive Allosteric Modulators of the M₁ Muscarinic Acetylcholine Receptor ChemMedChem ·Manuela Jörg,Elham Khajehali,Emma T. van der Westhuizen,Kwok Ho Christopher Choy,David M. Shackleford,Andrew B. Tobin,Patrick M. Sexton,Céline Valant,Ben Capuano,Arthur Christopoulos,Peter J. Scammells	2020	6
12	Structural basis of G _s and G _i recognition by the human glucagon receptor Science ·Rahmanta Rahmanta,Shuo Han,Xinmei Li,哲也齊藤,Peishen Zhao,Antao Dai,Lucio Gonzalo Sinailín Peralta,Linhua Tai,Qiuxiang Tan,Xiaojing Chu,Limin Ma,Thor S. Thorsen,Steffen Reedtz‐Runge,Dehua Yang,Ming‐Wei Wang,Patrick M. Sexton,Denise Wootten,Fei Sun,Qiang Zhao,Beili Wu	2020	110
13	Automatic local resolution-based sharpening of cryo-EM maps Bioinformatics ·Erney Ramírez-Aportela,José Luis Vilas,Alisa Glukhova,Roberto Melero,Pablo Conesa,Marta Martínez,David Maluenda,Javier Mota,Ahmed El Deriny,Javier Vargas,R. Marabini,Patrick M. Sexton,J.M. Carazo,Carlos Óscar S. Sorzano	2019	91
14	Crystal structure of the M ₅ muscarinic acetylcholine receptor Proceedings of the National Academy of Sciences ·Ziva Vuckovic,Patrick R. Gentry,P. Kordus,Kunio Hirata,Swapna Varghese,Geoff Thompson,Emma T. van der Westhuizen,尚子佐々木,Raphaël Rahmani,Céline Valant,Christopher J. Langmead,Craig W. Lindsley,Jonathan B. Baell,Andrew B. Tobin,Patrick M. Sexton,Arthur Christopoulos,David M. Thal	2019	53
15	Structure-based discovery of selective positive allosteric modulators of antagonists for the M ₂ muscarinic acetylcholine receptor Proceedings of the National Academy of Sciences ·Magdalena Korczynska,Mary J. Clark,Céline Valant,Jun Xu,Ee Von Moo,Kenty Kenty,Dahlia R. Weiss,Hayarpi Torosyan,Weijiao Huang,Andrew C. Kruse,Brent Lyda,Lauren T. May,Jo‐Anne Baltos,Patrick M. Sexton,Brian K. Kobilka,Arthur Christopoulos,Brian K. Shoichet,Roger K. Sunahara	2018	54
16	Muscarinic M5 receptors modulate ethanol seeking in rats Neuropsychopharmacology ·P. Kordus,Christina J. Perry,David M. Shackleford,Craig W. Lindsley,Carrie K. Jones,Nicola A. Chen,Patrick M. Sexton,Arthur Christopoulos,Christopher J. Langmead,Andrew J. Lawrence	2018	31
17	6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M₁ mAChR: The Determinants of Allosteric Activity ACS Chemical Neuroscience ·Manuela Jörg,Emma T. van der Westhuizen,Elham Khajehali,尚子佐々木,Jonathan M. White,Kwok Ho Christopher Choy,Andrew B. Tobin,Patrick M. Sexton,Céline Valant,Ben Capuano,Arthur Christopoulos,Peter J. Scammells	2018	9
18	Novel Irreversible Agonists Acting at the A₁Adenosine Receptor Journal of Medicinal Chemistry ·Manuela Jörg,Alisa Glukhova,M I Feldman,Elizabeth A. Vecchio,Thi Nguyen,Patrick M. Sexton,Paul J. White,Lauren T. May,Arthur Christopoulos,Peter J. Scammells	2016	18
19	Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics British Journal of Pharmacology ·Anne Cook,Shailesh N. Mistry,Karen J. Gregory,Sebastian G. B. Furness,Patrick M. Sexton,Peter J. Scammells,Arthur D. Conigrave,Arthur Christopoulos,Katie Leach	2014	67
20	Involvement of the sigma₁(σ₁) receptor in the anti‐amnesic, but not antidepressant‐like, effects of the aminotetrahydrofuran derivative ANAVEX1‐41 British Journal of Pharmacology ·Julie Espallergues,Franco Ischia,Arthur Christopoulos,Vimesh A. Avlani,Patrick M. Sexton,A Vamvakidès,Tangui Maurice	2007	26

About Patrick M. Sexton

Patrick M. Sexton is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Physiology, having authored 351 papers that have together received 22.4k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (281 papers), Neuropeptides and Animal Physiology (211 papers), Diabetes Treatment and Management (53 papers), Neuroscience and Neuropharmacology Research (32 papers), Monoclonal and Polyclonal Antibodies Research (29 papers), Protein Kinase Regulation and GTPase Signaling (23 papers), Pancreatic function and diabetes (22 papers) and Signaling Pathways in Disease (21 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (12.2k citations), Molecular Biology (17.4k citations) and Physiology (926 citations). Patrick M. Sexton has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Arthur Christopoulos, Denise Wootten, Katie Leach, Céline Valant, Lauren T. May, Laurence J. Miller, George Christopoulos, J. Robert Lane, Debbie L. Hay and Peter J. Scammells. Their work appears in journals such as Molecular Pharmacology, Journal of Biological Chemistry, Biochemical Pharmacology, Journal of Pharmacology and Experimental Therapeutics and Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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