Christopher J. Langmead

5.5k citations

85 papers · 4.0k indexed · 1 hit paper · h-index 33

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 0.5%
Physiology top 0.5%
Radiology, Nuclear Medicine and Imaging top 5%
Computational Theory and Mathematics top 1%

Co-authors: Arthur Christopoulos Jeannette M. Watson Guillaume Lebon K.A. Bennett Charlie Reavill Christopher G. Tate Andrew G. W. Leslie Patricia C. Edwards
Topics: Receptor Mechanisms and Signaling (67 papers)Neuroscience and Neuropharmacology Research (26 papers)Neuropeptides and Animal Physiology (25 papers)
Cited by: Physiology Cellular and Molecular Neuroscience Molecular Biology
Journals: Nature Proceedings of the National Academy of Sciences PLoS ONE
Partner nations: Australia United Kingdom United States

In The Last Decade

Christopher J. Langmead

85 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

2011 700 citations Christopher J. Langmead et al. profile →

Peers

Countries citing papers authored by Christopher J. Langmead

Since Specialization

Citations

This map shows the geographic impact of Christopher J. Langmead's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher J. Langmead with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher J. Langmead more than expected).

Fields of papers citing papers by Christopher J. Langmead

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher J. Langmead. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher J. Langmead. The network helps show where Christopher J. Langmead may publish in the future.

Co-authorship network of co-authors of Christopher J. Langmead

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher J. Langmead. A scholar is included among the top collaborators of Christopher J. Langmead based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher J. Langmead. Christopher J. Langmead is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Targeting muscarinic receptors for the treatment of alcohol use disorders: Opportunities and hurdles for clinical development 2023 ·British Journal of Pharmacology ·Leigh C. Walker,(unknown),Howard C. Becker,Christopher J. Langmead,Andrew J. Lawrence	7
2	Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors 2022 ·Molecular Pharmacology ·Jon Merlin,Julia Park,Teresa H. Vandekolk,Stewart A. Fabb,(unknown),Roger J. Summers,Christopher J. Langmead,Darren Riddy	16
3	Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics 2022 ·Translational Psychiatry ·(unknown),Alex Fornito,Christopher J. Langmead,Gregory D. Stewart	31
4	M₁ muscarinic receptor activation decreases alcohol consumption via a reduction in consummatory behavior 2021 ·Pharmacology Research & Perspectives ·Leigh C. Walker,Erin J. Campbell,(unknown),Nicola A. Chen,Christopher J. Langmead,Andrew J. Lawrence	9
5	Muscarinic M₄ and M₅ receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol‐preferring rats 2021 ·British Journal of Pharmacology ·Leigh C. Walker,(unknown),Nicola A. Chen,(unknown),Craig W. Lindsley,Christopher J. Langmead,Andrew J. Lawrence	17
6	Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents 2020 ·Biological Psychiatry ·Leigh C. Walker,(unknown),Nicola A. Chen,Patricia Rueda,Victoria M. Perreau,(unknown),(unknown),Piyarat Govitrapong,Xiaojian Jia,Craig W. Lindsley,Carrie K. Jones,Darren Riddy,Arthur Christopoulos,Christopher J. Langmead,Andrew J. Lawrence	30
7	Structure-based development of a subtype-selective orexin 1 receptor antagonist 2020 ·Proceedings of the National Academy of Sciences ·(unknown),(unknown),Jie Yin,Jakub Gunera,(unknown),(unknown),Christopher J. Langmead,Harald Hübner,Dorothée Weikert,Peter Kolb,Daniel M. Rosenbaum,Peter Gmeiner	41
8	Crystal structure of the M ₅ muscarinic acetylcholine receptor 2019 ·Proceedings of the National Academy of Sciences ·Ziva Vuckovic,Patrick R. Gentry,(unknown),Kunio Hirata,Swapna Varghese,Geoff Thompson,Emma T. van der Westhuizen,(unknown),Raphaël Rahmani,Céline Valant,Christopher J. Langmead,Craig W. Lindsley,Jonathan B. Baell,Andrew B. Tobin,Patrick M. Sexton,Arthur Christopoulos,David M. Thal	53
9	Muscarinic M5 receptors modulate ethanol seeking in rats 2018 ·Neuropsychopharmacology ·(unknown),Christina J. Perry,David M. Shackleford,Craig W. Lindsley,Carrie K. Jones,Nicola A. Chen,Patrick M. Sexton,Arthur Christopoulos,Christopher J. Langmead,Andrew J. Lawrence	31
10	G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus 2017 ·Pharmacological Reviews ·Darren Riddy,Philippe Delerive,Roger J. Summers,Patrick M. Sexton,Christopher J. Langmead	88
11	Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators 2016 ·Molecular Pharmacology ·(unknown),Patrick R. Gentry,Patricia Rueda,Sandra den Hoedt,Patrick M. Sexton,Christopher J. Langmead,Arthur Christopoulos	23
12	Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor Antagonists 2015 ·Molecular Pharmacology ·Darren Riddy,Céline Valant,Patricia Rueda,William N. Charman,Patrick M. Sexton,Roger J. Summers,Arthur Christopoulos,Christopher J. Langmead	17
13	The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery 2010 ·Neuropharmacology ·N.J. Robertson,Ali Jazayeri,James C. Errey,Asma Baig,Edward Hurrell,Andrei Zhukov,Christopher J. Langmead,Malcolm Weir,Fiona H. Marshall	126
14	Contrasting Effects of Allosteric and Orthosteric Agonists on M1 Muscarinic Acetylcholine Receptor Internalization and Down-regulation 2009 ·Journal of Pharmacology and Experimental Therapeutics ·(unknown),Christopher J. Langmead,Martyn Wood,R. A. John Challiss	32
15	Screening for Positive Allosteric Modulators: Assessment of Modulator Concentration-Response Curves as a Screening Paradigm 2007 ·SLAS DISCOVERY ·Christopher J. Langmead	5
16	Structure-Function Studies of Allosteric Agonism at M2 Muscarinic Acetylcholine Receptors 2007 ·Molecular Pharmacology ·Lauren T. May,Vimesh A. Avlani,Christopher J. Langmead,Hugh J. Herdon,Martyn Wood,Patrick M. Sexton,Arthur Christopoulos	98
17	Roof and Floor of the Muscarinic Binding Pocket: Variations in the Binding Modes of Orthosteric Ligands 2007 ·Molecular Pharmacology ·(unknown),Edward C. Hulme,Christopher J. Langmead,B.G. Tehan	37
18	SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue 2006 ·European Journal of Pharmacology ·Claire M. Scott,Ellen M. Soffin,Matthew Hill,Peter J. Atkinson,Christopher J. Langmead,Paul Wren,(unknown),Laurie Gordon,Gary Price,(unknown),(unknown),J.J. Hagan,Jeannette M. Watson	13
19	Neurochemical Changes in LPA1 Receptor Deficient Mice – A Putative Model of Schizophrenia 2005 ·Neurochemical Research ·Claire Roberts,(unknown),Claire S Shilliam,Zoë A. Hughes,Christopher J. Langmead,Peter R. Maycox,Lee A. Dawson	56
20	Probing the Molecular Mechanism of Interaction between 4-n-Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist 2005 ·Molecular Pharmacology ·Christopher J. Langmead,(unknown),Ian T. Forbes,Clive L. Branch,Arthur Christopoulos,Martyn Wood,Hugh J. Herdon	90

About Christopher J. Langmead

Christopher J. Langmead is a scholar working on Cellular and Molecular Neuroscience, Physiology and Biological Psychiatry, having authored 85 papers that have together received 4.0k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (67 papers), Neuroscience and Neuropharmacology Research (26 papers) and Neuropeptides and Animal Physiology (25 papers). The work is most often cited by research in Physiology (500 citations), Cellular and Molecular Neuroscience (1.9k citations) and Molecular Biology (3.0k citations). Christopher J. Langmead has collaborated with scholars based in Australia, United Kingdom and United States. Frequent co-authors include Arthur Christopoulos, Jeannette M. Watson, Guillaume Lebon, K.A. Bennett, Charlie Reavill, Christopher G. Tate, Andrew G. W. Leslie, Patricia C. Edwards, Tony Warne and Patrick M. Sexton. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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