Kyle A. Emmitte

3.2k citations

68 papers · 2.2k indexed · h-index 29

Impact in

Cellular and Molecular Neuroscience top 2%
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
Biological Psychiatry top 5%

Papers in

Cellular and Molecular Neuroscience 44
- Neuroscience and Neuropharmacology Research 41
Toxicology 3

Co-authors: Craig W. Lindsley Michael T. Crimmins P. Jeffrey Conn Colleen M. Niswender Corey R. Hopkins Alice L. Rodriguez Andrew S. Felts Karen J. Gregory
Journals: Bioorganic & Medicinal Chemistry Letters (14 papers)Journal of Medicinal Chemistry (8 papers)ACS Chemical Neuroscience (7 papers)Organic Letters (4 papers)Expert Opinion on Therapeutic Patents (3 papers)
Partner nations: United States Australia United Kingdom

In The Last Decade

Kyle A. Emmitte

65 papers receiving 2.1k citations

Peers

Countries citing papers authored by Kyle A. Emmitte

Since Specialization

Citations

This map shows the geographic impact of Kyle A. Emmitte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kyle A. Emmitte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kyle A. Emmitte more than expected).

Fields of papers citing papers by Kyle A. Emmitte

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kyle A. Emmitte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kyle A. Emmitte. The network helps show where Kyle A. Emmitte may publish in the future.

Co-authors

The 25 scholars most cited alongside Kyle A. Emmitte, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kyle A. Emmitte Line = papers co-authored together Kyle A. Emmitte links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14 Journal of Biological Chemistry ·Percy S. Agogo-Mawuli, Isra Sadiya, Tigran M. Abramyan, Dustin E. Bosch, Kyle A. Emmitte, Luis M. Colón-Pérez, Mickey Kosloff, David P. Siderovski	2025	0
2	I-GAT: Interpretable Graph Attention Networks for Ligand Optimization ACS Omega ·Ezek Mathew, Kyle A. Emmitte, Jin Liu	2025	0
3	Structure–Activity Relationship Studies in a Series of 2-Aryloxy-N-(pyrimidin-5-yl)acetamide Inhibitors of SLACK Potassium Channels Molecules ·Nigam M. Mishra, Brittany D. Spitznagel, Yu Du, Y. Mohamed, Ying� Qin, C. David Weaver, Kyle A. Emmitte	2024	0
4	Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685 Bioorganic & Medicinal Chemistry ·Alshaima’a M. Qunies, Brittany D. Spitznagel, Yu Du, C. David Weaver, Kyle A. Emmitte	2023	9
5	Quercetin and Related Analogs as Therapeutics to Promote Tissue Repair Bioengineering ·Tina B. McKay, Kyle A. Emmitte, Carrie German, Dimitrios Karamichos	2023	18
6	Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5 Bioorganic & Medicinal Chemistry Letters ·Andrew S. Felts, Katrina A. Bollinger, Christopher J. Brassard, Alice L. Rodriguez, Ryan D. Morrison, J. Scott Daniels, Anna L. Blobaum, Colleen M. Niswender, Carrie K. Jones, P. Jeffrey Conn, Kyle A. Emmitte, Craig W. Lindsley	2018	4
7	Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation Neuropsychopharmacology ·Adam G. Walker, Douglas J. Sheffler, Andrew Lewis, Jonathan W. Dickerson, Daniel J. Foster, Rebecca K. Senter, Mark S. Moehle, Xiaohui Lv, Branden J. Stansley, Zixiu Xiang, Jerri M. Rook, Kyle A. Emmitte, Craig W. Lindsley, P. Jeffrey Conn	2017	16
8	Evaluating the Disposition of a Mixed Aldehyde Oxidase/Cytochrome P450 Substrate in Rats with Attenuated P450 Activity Drug Metabolism and Disposition ·Robert D. Crouch, R Morrison, Frank W. Byers, Craig W. Lindsley, Kyle A. Emmitte, J. Scott Daniels	2016	18
9	VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy Journal of Pharmacology and Experimental Therapeutics ·Hilary Highfield Nickols, Johannes P Yuh, Karen J. Gregory, R Morrison, Brittney S. Bates, Shaun R. Stauffer, Kyle A. Emmitte, Michael Bubser, Wenjie Peng, Michael T. Nedelcovych, Analisa D. Thompson, Xiaohua Lv, Zixiu Xiang, J. Scott Daniels, Colleen M. Niswender, Craig W. Lindsley, Carrie K. Jones, P. Jeffrey Conn	2015	28
10	A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and Human Receptors ACS Chemical Neuroscience ·Hyekyung P. Cho, Darren W. Engers, Daryl F. Venable, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Kyle A. Emmitte, Alice L. Rodriguez	2014	47
11	Relationship between In Vivo Receptor Occupancy and Efficacy of Metabotropic Glutamate Receptor Subtype 5 Allosteric Modulators with Different In Vitro Binding Profiles Neuropsychopharmacology ·Jerri M. Rook, Mohammed Noor Tantawy, M. Sib Ansari, Andrew S. Felts, Shaun R. Stauffer, Kyle A. Emmitte, Robert Kessler, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn	2014	33
12	Discovery of (R)-(2-Fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-Hydroxypiperidin-1-yl)methanone (ML337), An mGlu₃ Selective and CNS Penetrant Negative Allosteric Modulator (NAM) Journal of Medicinal Chemistry ·Cody J. Wenthur, Ryan D. Morrison, Andrew S. Felts, Katrina A. Smith, Julie L. Engers, Frank W. Byers, J. Scott Daniels, Kyle A. Emmitte, P. Jeffrey Conn, Craig W. Lindsley	2013	47
13	Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety Bioorganic & Medicinal Chemistry Letters ·Andrew S. Felts, Alice L. Rodriguez, Ryan D. Morrison, Daryl F. Venable, Jason Manka, Brittney S. Bates, Anna L. Blobaum, Frank W. Byers, J. Scott Daniels, Colleen M. Niswender, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte	2013	27
14	N-Acyl-N′-arylpiperazines as negative allosteric modulators of mGlu1: Identification of VU0469650, a potent and selective tool compound with CNS exposure in rats Bioorganic & Medicinal Chemistry Letters ·Kimberly M. Lovell, Andrew S. Felts, Alice L. Rodriguez, Daryl F. Venable, Hyekyung P. Cho, Ryan D. Morrison, Frank W. Byers, J. Scott Daniels, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte	2013	13
15	Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1 Bioorganic & Medicinal Chemistry Letters ·Jason Manka, Alice L. Rodriguez, Ryan D. Morrison, Daryl F. Venable, Hyekyung P. Cho, Anna L. Blobaum, J. Scott Daniels, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte	2013	9
16	Substituted 1-Phenyl-3-(pyridin-2-yl)urea Negative Allosteric Modulators of mGlu₅: Discovery of a New Tool Compound VU0463841 with Activity in Rat Models of Cocaine Addiction ACS Chemical Neuroscience ·Russell J. Amato, Andrew S. Felts, Alice L. Rodriguez, Daryl F. Venable, Ryan D. Morrison, Frank W. Byers, J. Scott Daniels, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Carrie K. Jones, Kyle A. Emmitte	2013	14
17	Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery Journal of Medicinal Chemistry ·Bruce J. Melancon, Corey R. Hopkins, Michael R. Wood, Kyle A. Emmitte, Colleen M. Niswender, Arthur Christopoulos, P. Jeffrey Conn, Craig W. Lindsley	2011	188
18	(3-Cyano-5-fluorophenyl)biaryl Negative Allosteric Modulators of mGlu₅: Discovery of a New Tool Compound with Activity in the OSS Mouse Model of Addiction ACS Chemical Neuroscience ·Craig W. Lindsley, Brittney S. Bates, Usha N. Menon, Satyawan Jadhav, Alexander S. Kane, Carrie K. Jones, Alice L. Rodriguez, P. Jeffrey Conn, Christopher M. Olsen, Danny G. Winder, Kyle A. Emmitte	2011	18
19	Discovery of a new molecular probe ML228: An activator of the hypoxia inducible factor (HIF) pathway Bioorganic & Medicinal Chemistry Letters ·Jimmy R. Thériault, Andrew S. Felts, Brittney S. Bates, José R. Perez, Michelle Palmer, Shawn R. Gilbert, Eric S. Dawson, Julie L. Engers, Craig W. Lindsley, Kyle A. Emmitte	2011	24
20	Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase Clinical Cancer Research ·Peter Sabbatini, Jason L. Rowand, Arthur Groy, Susan Korenchuk, Qi Liu, Charity Atkins, Melissa Dumble, Jingsong Yang, Kelly K. Anderson, Brian J. Wilson, Kyle A. Emmitte, Sridhar K. Rabindran, Rakesh Kumar	2009	62

About Kyle A. Emmitte

Kyle A. Emmitte is a scholar working on Cellular and Molecular Neuroscience, Toxicology, Molecular Biology, Environmental Chemistry and Biotechnology, having authored 68 papers that have together received 2.2k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (41 papers), Receptor Mechanisms and Signaling (25 papers), Pharmacological Receptor Mechanisms and Effects (10 papers), Ion channel regulation and function (10 papers), Chemical Synthesis and Analysis (8 papers), Synthetic Organic Chemistry Methods (8 papers), Marine Toxins and Detection Methods (5 papers) and Nicotinic Acetylcholine Receptors Study (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.0k citations), Biological Psychiatry (67 citations), Molecular Biology (1.4k citations), Organic Chemistry (550 citations) and Toxicology (49 citations). Kyle A. Emmitte has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Craig W. Lindsley, Michael T. Crimmins, P. Jeffrey Conn, Colleen M. Niswender, Corey R. Hopkins, Alice L. Rodriguez, Andrew S. Felts, Karen J. Gregory, J. Scott Daniels and Carrie K. Jones. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Chemical Neuroscience, Organic Letters and Expert Opinion on Therapeutic Patents.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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