Meredith J. Noetzel

1.6k citations

33 papers · 925 indexed · h-index 17

Molecular Biology top 10%
Cellular and Molecular Neuroscience top 2%
Cognitive Neuroscience
Computational Theory and Mathematics top 10%
Organic Chemistry

Co-authors: P. Jeffrey Conn Colleen M. Niswender Craig W. Lindsley Karen J. Gregory Carrie K. Jones Shaun R. Stauffer Jerri M. Rook Paige N. Vinson
Topics: Receptor Mechanisms and Signaling (28 papers)Neuroscience and Neuropharmacology Research (21 papers)Ion channel regulation and function (9 papers)
Cited by: Cellular and Molecular Neuroscience Molecular Biology Biological Psychiatry
Journals: Journal of Neuroscience PLoS ONE Biological Psychiatry
Partner nations: United States Australia Belgium

In The Last Decade

Meredith J. Noetzel

33 papers receiving 915 citations

Peers

Countries citing papers authored by Meredith J. Noetzel

Since Specialization

Citations

This map shows the geographic impact of Meredith J. Noetzel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Meredith J. Noetzel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Meredith J. Noetzel more than expected).

Fields of papers citing papers by Meredith J. Noetzel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Meredith J. Noetzel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Meredith J. Noetzel. The network helps show where Meredith J. Noetzel may publish in the future.

Co-authorship network of co-authors of Meredith J. Noetzel

This figure shows the co-authorship network connecting the top 25 collaborators of Meredith J. Noetzel. A scholar is included among the top collaborators of Meredith J. Noetzel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Meredith J. Noetzel. Meredith J. Noetzel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	In Vitro to in Vivo Translation of Allosteric Modulator Concentration-Effect Relationships: Implications for Drug Discovery 2019 ·ACS Pharmacology & Translational Science ·Karen J. Gregory,Thomas M. Bridges,Rocco G. Gogliotti,Shaun R. Stauffer,Meredith J. Noetzel,Carrie K. Jones,Craig W. Lindsley,P. Jeffrey Conn,Colleen M. Niswender	6
2	Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides 2017 ·Bioorganic & Medicinal Chemistry Letters ·James C. Tarr,Michael R. Wood,Meredith J. Noetzel,(unknown),Rebecca L. Weiner,Alice L. Rodriguez,Atin Lamsal,Frank W. Byers,Sichen Chang,Hyekyung P. Cho,Carrie K. Jones,Colleen M. Niswender,Michael W. Wood,Nicholas J. Brandon,Mark E. Duggan,P. Jeffrey Conn,Thomas M. Bridges,Craig W. Lindsley	16
3	Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides 2017 ·Bioorganic & Medicinal Chemistry Letters ·James C. Tarr,Michael R. Wood,Meredith J. Noetzel,Bruce J. Melancon,Atin Lamsal,Vincent B. Luscombe,Alice L. Rodriguez,Frank W. Byers,Sichen Chang,Hyekyung P. Cho,Darren W. Engers,Carrie K. Jones,Colleen M. Niswender,Michael W. Wood,Nicholas J. Brandon,Mark E. Duggan,P. Jeffrey Conn,Thomas M. Bridges,Craig W. Lindsley	11
4	Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition 2016 ·Bioorganic & Medicinal Chemistry Letters ·Michael R. Wood,Meredith J. Noetzel,James C. Tarr,Alice L. Rodriguez,Atin Lamsal,Sichen Chang,(unknown),Emery Smith,Peter Chase,Peter Hodder,Darren W. Engers,Colleen M. Niswender,Nicholas J. Brandon,Michael W. Wood,Mark E. Duggan,P. Jeffrey Conn,Thomas M. Bridges,Craig W. Lindsley	7
5	Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4) 2015 ·SLAS DISCOVERY ·Emery Smith,Peter Chase,Colleen M. Niswender,Thomas J. Utley,Douglas J. Sheffler,Meredith J. Noetzel,Atin Lamsal,Michael R. Wood,P. Jeffrey Conn,Craig W. Lindsley,Franck Madoux,(unknown),Louis Scampavia,Timothy Spicer,Peter Hodder	25
6	Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5) 2015 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),José Manuel Bartolomé-Nebreda,(unknown),(unknown),Silvia N. López,(unknown),(unknown),Hilde Lavreysen,Gregor J. Macdonald,Thomas Steckler,Claire Mackie,Thomas M. Bridges,J. Scott Daniels,Colleen M. Niswender,Meredith J. Noetzel,Carrie K. Jones,P. Jeffrey Conn,Craig W. Lindsley,Shaun R. Stauffer	6
7	Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model 2015 ·Neuropsychopharmacology ·Ayan Ghoshal,Jerri M. Rook,Jonathan W. Dickerson,(unknown),Ryan D. Morrison,Nidhi Jalan‐Sakrikar,Atin Lamsal,Meredith J. Noetzel,Michael S. Poslusney,Michael R. Wood,Bruce J. Melancon,Shaun R. Stauffer,Zixiu Xiang,J. Scott Daniels,Colleen M. Niswender,Carrie K. Jones,Craig W. Lindsley,P. Jeffrey Conn	81
8	State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 – Relation to antipsychotic-like drug effects 2015 ·Neuropharmacology ·Robert W. Gould,Michael T. Nedelcovych,(unknown),(unknown),Michael Bubser,Thomas M. Bridges,Michael R. Wood,Mark E. Duggan,Nicholas J. Brandon,John Dunlop,Michael W. Wood,Magnus Ivarsson,Meredith J. Noetzel,J. Scott Daniels,Colleen M. Niswender,Craig W. Lindsley,P. Jeffrey Conn,Carrie K. Jones	26
9	Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-Dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators 2014 ·Bioorganic & Medicinal Chemistry Letters ·Changho Han,Arindam Chatterjee,Meredith J. Noetzel,Joseph D. Panarese,Emery Smith,Peter Chase,Peter Hodder,Colleen M. Niswender,P. Jeffrey Conn,Craig W. Lindsley,Shaun R. Stauffer	6
10	Development of a Highly Potent, Novel M₅Positive Allosteric Modulator (PAM) Demonstrating CNS Exposure: 1-((1H-Indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380) 2014 ·Journal of Medicinal Chemistry ·Patrick R. Gentry,Masaya Kokubo,Thomas M. Bridges,Meredith J. Noetzel,Hyekyung P. Cho,Atin Lamsal,Emery Smith,Peter Chase,Peter Hodder,Colleen M. Niswender,J. Scott Daniels,P. Jeffrey Conn,Craig W. Lindsley,Michael R. Wood	22
11	Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiency 2014 ·Bioorganic & Medicinal Chemistry Letters ·Mark Turlington,Meredith J. Noetzel,Thomas M. Bridges,Paige N. Vinson,Thomas Steckler,Hilde Lavreysen,Claire Mackie,José Manuel Bartolomé-Nebreda,(unknown),(unknown),Gregor J. Macdonald,J. Scott Daniels,Carrie K. Jones,Colleen M. Niswender,P. Jeffrey Conn,Craig W. Lindsley,Shaun R. Stauffer	7
12	A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling 2013 ·Molecular Pharmacology ·Meredith J. Noetzel,Karen J. Gregory,Paige N. Vinson,Jason Manka,Shaun R. Stauffer,Craig W. Lindsley,Colleen M. Niswender,Zixiu Xiang,P. Jeffrey Conn	57
13	Selective Actions of Novel Allosteric Modulators Reveal Functional Heteromers of Metabotropic Glutamate Receptors in the CNS 2013 ·Journal of Neuroscience ·Yin Shen,Meredith J. Noetzel,Kari A. Johnson,Rocio Zamorano,Nidhi Jalan‐Sakrikar,Karen J. Gregory,P. Jeffrey Conn,Colleen M. Niswender	103
14	Unique Signaling Profiles of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Determine Differences in In Vivo Activity 2012 ·Biological Psychiatry ·Jerri M. Rook,Meredith J. Noetzel,Wendy A. Pouliot,Thomas M. Bridges,Paige N. Vinson,Hyekyung P. Cho,Ya Zhou,Rocco D. Gogliotti,Jason Manka,Karen J. Gregory,Shaun R. Stauffer,F. Edward Dudek,Zixiu Xiang,Colleen M. Niswender,J. Scott Daniels,Carrie K. Jones,Craig W. Lindsley,P. Jeffrey Conn	73
15	Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function 2011 ·Molecular Pharmacology ·Meredith J. Noetzel,Jerri M. Rook,Paige N. Vinson,Hyekyung P. Cho,Emily Days,(unknown),Alice L. Rodriguez,Hilde Lavreysen,Shaun R. Stauffer,Colleen M. Niswender,Zixiu Xiang,J. Scott Daniels,Carrie K. Jones,Craig W. Lindsley,C. David Weaver,P. Jeffrey Conn	99
16	Development of a more highly selective M1 antagonist from the continued optimization of the MLPCN Probe ML012 2011 ·Bioorganic & Medicinal Chemistry Letters ·Bruce J. Melancon,(unknown),Thomas M. Bridges,Gary A. Sulikowski,Thomas J. Utley,Douglas J. Sheffler,Meredith J. Noetzel,Ryan D. Morrison,(unknown),Colleen M. Niswender,Carrie K. Jones,(unknown),(unknown),Michael R. Wood	6
17	Pharmacological Evaluation of the Long-Term Effects of Xanomeline on the M1 Muscarinic Acetylcholine Receptor 2010 ·PLoS ONE ·Marianne Grant,Meredith J. Noetzel,(unknown),Ján Jakubík,Vladimı́r Doležal,Esam E. El‐Fakahany	6
18	Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAM 2010 ·Bioorganic & Medicinal Chemistry Letters ·Thomas M. Bridges,J. Phillip Kennedy,Meredith J. Noetzel,(unknown),Patrick R. Gentry,P. Jeffrey Conn,Craig W. Lindsley	44
19	Mechanisms of M3 Muscarinic Receptor Regulation by Wash-Resistant Xanomeline Binding 2009 ·Pharmacology ·Meredith J. Noetzel,Marianne Grant,Esam E. El‐Fakahany	4
20	Long-Term Changes in the Muscarinic M1 Receptor Induced by Instantaneous Formation of Wash-Resistant Xanomeline-Receptor Complex 2007 ·Journal of Pharmacology and Experimental Therapeutics ·(unknown),Marianne Grant,Meredith J. Noetzel,(unknown),Esam E. El‐Fakahany	6

About Meredith J. Noetzel

Meredith J. Noetzel is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Biological Psychiatry, having authored 33 papers that have together received 925 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (28 papers), Neuroscience and Neuropharmacology Research (21 papers) and Ion channel regulation and function (9 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (698 citations), Molecular Biology (783 citations) and Biological Psychiatry (28 citations). Meredith J. Noetzel has collaborated with scholars based in United States, Australia and Belgium. Frequent co-authors include P. Jeffrey Conn, Colleen M. Niswender, Craig W. Lindsley, Karen J. Gregory, Carrie K. Jones, Shaun R. Stauffer, Jerri M. Rook, Paige N. Vinson, Zixiu Xiang and J. Scott Daniels. Their work appears in journals such as Journal of Neuroscience, PLoS ONE and Biological Psychiatry.

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