Paul K. Spearing

664 total citations
16 papers, 559 citations indexed

About

Paul K. Spearing is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Oncology. According to data from OpenAlex, Paul K. Spearing has authored 16 papers receiving a total of 559 indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 4 papers in Cellular and Molecular Neuroscience and 4 papers in Oncology. Recurrent topics in Paul K. Spearing's work include Receptor Mechanisms and Signaling (7 papers), Drug Transport and Resistance Mechanisms (4 papers) and Neuroscience and Neuropharmacology Research (4 papers). Paul K. Spearing is often cited by papers focused on Receptor Mechanisms and Signaling (7 papers), Drug Transport and Resistance Mechanisms (4 papers) and Neuroscience and Neuropharmacology Research (4 papers). Paul K. Spearing collaborates with scholars based in United States, Brazil and Denmark. Paul K. Spearing's co-authors include Shawn P. Williams, G. Bruce Wisely, Dan Todd, Katrina L. Creech, Aaron B. Miller, Derek J. Parks, Frank Navas, Kevin P. Madauss, David N. Deaton and Justin A. Caravella and has published in prestigious journals such as Journal of Agricultural and Food Chemistry, Journal of Medicinal Chemistry and Phytochemistry.

In The Last Decade

Paul K. Spearing

15 papers receiving 533 citations

Peers

Countries citing papers authored by Paul K. Spearing

Since Specialization

Citations

This map shows the geographic impact of Paul K. Spearing's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul K. Spearing with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul K. Spearing more than expected).

Fields of papers citing papers by Paul K. Spearing

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul K. Spearing. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul K. Spearing. The network helps show where Paul K. Spearing may publish in the future.

Co-authorship network of co-authors of Paul K. Spearing

This figure shows the co-authorship network connecting the top 25 collaborators of Paul K. Spearing. A scholar is included among the top collaborators of Paul K. Spearing based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul K. Spearing. Paul K. Spearing is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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16 of 16 papers shown

#	Work	Indexed citations
1	Discovery of a Novel sp³-Rich M₁ Positive Allosteric Modulators (PAMs) Chemotype via Scaffold Hopping 2025 ·ACS Medicinal Chemistry Letters ·(unknown), Paul K. Spearing, (unknown), (unknown), (unknown), Sichen Chang, (unknown), Analisa D. Thompson, Hyekyung P. Cho, Peng Li, Alice L. Rodriguez, Colleen M. Niswender, Olivier Boutaud, Valerie M. Kramlinger, Carrie K. Jones, P. Jeffrey Conn, Julie L. Engers, Darren W. Engers, Craig W. Lindsley, Changho Han	0
2	Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M1 2021 ·Bioorganic & Medicinal Chemistry Letters ·Paul K. Spearing, Hyekyung P. Cho, Vincent B. Luscombe, Anna L. Blobaum, Olivier Boutaud, Darren W. Engers, Alice L. Rodriguez, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Aaron M. Bender	3
3	Discovery of structurally distinct tricyclic M4 positive allosteric modulator (PAM) chemotypes – Part 2 2021 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), (unknown), Paul K. Spearing, Julie L. Engers, Alison R. Gregro, (unknown), Sichen Chang, Vincent B. Luscombe, Alice L. Rodriguez, Hyekyung P. Cho, Colleen M. Niswender, Thomas M. Bridges, P. Jeffrey Conn, Craig W. Lindsley, Darren W. Engers, Kayla J. Temple	4
4	Synthesis and SAR of a series of mGlu7 NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core 2020 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), (unknown), (unknown), Paul K. Spearing, (unknown), (unknown), Alice L. Rodriguez, Anna L. Blobaum, P. Jeffrey Conn, Colleen M. Niswender, Craig W. Lindsley	8
5	Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration 2017 ·Bioorganic & Medicinal Chemistry Letters ·Steven M. Sparks, Paul K. Spearing, (unknown), David J. Cowan, Channa Jayawickreme, Grace Chen, Thomas J. Rimele, (unknown), (unknown), Shane Roller	6
6	Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core 2017 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Paul K. Spearing, Rebecca L. Weiner, Vincent B. Luscombe, Xiaoyan Zhan, Sichen Chang, Hyekyung P. Cho, Alice L. Rodriguez, Colleen M. Niswender, P. Jeffrey Conn, Thomas M. Bridges, Darren W. Engers, Craig W. Lindsley	6
7	VU6010608, a Novel mGlu₇ NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides 2017 ·ACS Medicinal Chemistry Letters ·(unknown), Kevin McGowan, Paul K. Spearing, Branden J. Stansley, (unknown), Darren W. Engers, Alice L. Rodriguez, (unknown), Vincent B. Luscombe, (unknown), (unknown), Jerri M. Rook, Anna L. Blobaum, P. Jeffrey Conn, Colleen M. Niswender, Craig W. Lindsley	20
8	Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	28
9	Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene 2010 ·Bioorganic & Medicinal Chemistry Letters ·Jonathan Y. Bass, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Wendy Y. Mills, Frank Navas, Derek J. Parks, Terrence L. Smalley, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	53
10	Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists 2010 ·Journal of Medicinal Chemistry ·William J. Zuercher, Richard G. Buckholz, Nino Campobasso, Jon L. Collins, Cristin M. Galardi, Robert T. Gampe, (unknown), (unknown), John T. Moore, Jeffrey A. Oplinger, Paul R. Reid, Paul K. Spearing, Thomas B. Stanley, Eugene L. Stewart, Timothy M. Willson	81
11	FXR agonist activity of conformationally constrained analogs of GW 4064 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	56
12	Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064 2008 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Stacey A. Jones, István Káldor, Yaping Liu, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	118
13	A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor β 2002 ·Journal of Medicinal Chemistry ·Brad R. Henke, Thomas G. Consler, Ning Go, Ron Hale, (unknown), Stacey A. Jones, Amy T. Lu, Linda B. Moore, John T. Moore, Lisa A. Orband‐Miller, (unknown), Jean Shearin, Paul K. Spearing, Eugene L. Stewart, Philip Turnbull, (unknown), Shawn P. Williams, G. Bruce Wisely, Millard H. Lambert	139
14	Dioclenol, a minor flavanonol from the root-bark of Dioclea grandiflora 1997 ·Phytochemistry ·Jnanabrata Bhattacharyya, George Majetich, Paul K. Spearing, Reinaldo Nóbrega de Almeida	17
15	Syntheses of 3,7-Dimethyl-8-hydroxy-6-methoxyisochroman, the 3,7-Dimethyl-6-hydroxy-8-methoxy Isomer, and Their Ester and Ether Derivatives: Plant Growth Regulatory Activity 1997 ·Journal of Agricultural and Food Chemistry ·Horace G. Cutler, George Majetich, Xinrong Tian, Paul K. Spearing	13
16	Synthesis of (R,S)-Dioclein, a Bioactive Flavanone from the Root Bark of Diocleia grandiflora 1997 ·Journal of Natural Products ·Paul K. Spearing, George Majetich, Jnanabrata Bhattacharyya	7

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