Darren W. Engers

2.2k total citations
73 papers, 1.6k citations indexed

About

Darren W. Engers is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Organic Chemistry. According to data from OpenAlex, Darren W. Engers has authored 73 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 40 papers in Cellular and Molecular Neuroscience and 11 papers in Organic Chemistry. Recurrent topics in Darren W. Engers's work include Receptor Mechanisms and Signaling (37 papers), Neuroscience and Neuropharmacology Research (36 papers) and Pharmacological Receptor Mechanisms and Effects (18 papers). Darren W. Engers is often cited by papers focused on Receptor Mechanisms and Signaling (37 papers), Neuroscience and Neuropharmacology Research (36 papers) and Pharmacological Receptor Mechanisms and Effects (18 papers). Darren W. Engers collaborates with scholars based in United States, Japan and Russia. Darren W. Engers's co-authors include Craig W. Lindsley, Corey R. Hopkins, Colleen M. Niswender, P. Jeffrey Conn, Anna L. Blobaum, Alice L. Rodriguez, Carrie K. Jones, C. David Weaver, J. Scott Daniels and Hyekyung P. Cho and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Neuroscience and SHILAP Revista de lepidopterología.

In The Last Decade

Darren W. Engers

69 papers receiving 1.5k citations

Peers

Countries citing papers authored by Darren W. Engers

Since Specialization

Citations

This map shows the geographic impact of Darren W. Engers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren W. Engers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren W. Engers more than expected).

Fields of papers citing papers by Darren W. Engers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren W. Engers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren W. Engers. The network helps show where Darren W. Engers may publish in the future.

Co-authorship network of co-authors of Darren W. Engers

This figure shows the co-authorship network connecting the top 25 collaborators of Darren W. Engers. A scholar is included among the top collaborators of Darren W. Engers based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darren W. Engers. Darren W. Engers is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Application of Deuterium in an M₁ Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422 2025 ·ACS Chemical Neuroscience ·Julie L. Engers, (unknown), Changho Han, (unknown), Alison R. Gregro, (unknown), Jonathan W. Dickerson, Weimin Peng, Hyekyung P. Cho, Alice L. Rodriguez, Zixiu Xiang, Olivier Boutaud, C. O’Carroll, Prabuddha Dey, Ethan S. Burstein, Colleen M. Niswender, Jerri M. Rook, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley	0
2	Discovery of ONO-2920632 (VU6011887): A Highly Selective and CNS Penetrant TREK-2 (TWIK-Related K+ Channel 2) Preferring Activator In Vivo Tool Compound 2025 ·ACS Chemical Neuroscience ·(unknown), (unknown), H Urata, Masaya Kokubo, Takahiro Mori, (unknown), (unknown), Junya Kato, Joshua M. Wieting, Kevin McGowan, Thomas M. Bridges, Olivier Boutaud, Darren W. Engers, Jerod S. Denton, H. Kurata, Craig W. Lindsley	1
3	Discovery of VU6007496: Challenges in the Development of an M₁ Positive Allosteric Modulator Backup Candidate 2024 ·ACS Chemical Neuroscience ·Julie L. Engers, (unknown), (unknown), (unknown), Aaron M. Bender, Jonathan W. Dickerson, Weimin Peng, (unknown), Hyekyung P. Cho, Alice L. Rodriguez, Colleen M. Niswender, Sean P. Moran, Zixiu Xiang, Anna L. Blobaum, Olivier Boutaud, (unknown), Darren W. Engers, P. Jeffrey Conn, Craig W. Lindsley	3
4	Discovery of VU6008677: A Structurally Distinct Tricyclic M₄ Positive Allosteric Modulator with Improved CYP450 Profile 2024 ·ACS Medicinal Chemistry Letters ·(unknown), (unknown), Julie L. Engers, (unknown), Sichen Chang, Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, Thomas M. Bridges, Olivier Boutaud, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley, Kayla J. Temple	2
5	Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) 2024 ·ACS Chemical Neuroscience ·Julie L. Engers, (unknown), Sichen Chang, Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, Hyekyung P. Cho, Michael Bubser, (unknown), Carrie K. Jones, Weimin Peng, Jerri M. Rook, Thomas M. Bridges, Olivier Boutaud, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley, Kayla J. Temple	1
6	Discovery of “Molecular Switches” within a Series of mGlu₅ Allosteric Ligands Driven by a “Magic Methyl” Effect Affording Both PAMs and NAMs with In Vivo Activity, Derived from an M₁ PAM Chemotype 2021 ·SHILAP Revista de lepidopterología ·Lisa Barbaro, Alice L. Rodriguez, (unknown), Jonathan W. Dickerson, (unknown), Olivier Boutaud, (unknown), Colleen M. Niswender, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley	3
7	Surveying heterocycles as amide bioisosteres within a series of mGlu7 NAMs: Discovery of VU6019278 2019 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), (unknown), (unknown), (unknown), Alice L. Rodriguez, Darren W. Engers, Anna L. Blobaum, P. Jeffrey Conn, Colleen M. Niswender, Craig W. Lindsley	14
8	Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063 2019 ·Journal of Pharmacology and Experimental Therapeutics ·Sujay V. Kharade, Juan V. Sanchez‐Andrés, (unknown), Elaine L. Shelton, Anna L. Blobaum, Darren W. Engers, (unknown), Prasanna K. Dadi, Louise Lantier, David A. Jacobson, Craig W. Lindsley, Jerod S. Denton	13
9	Discovery of a novel 3,4-dimethylcinnoline carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping 2019 ·Bioorganic & Medicinal Chemistry Letters ·Kayla J. Temple, Julie L. Engers, (unknown), Alison R. Gregro, (unknown), Sichen Chang, (unknown), Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, Thomas M. Bridges, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley	9
10	M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition 2018 ·Neuropsychopharmacology ·Sean P. Moran, Jonathan W. Dickerson, Hyekyung P. Cho, Zixiu Xiang, James Maksymetz, (unknown), Xiaohui Lv, Catherine A. Doyle, (unknown), Colleen M. Niswender, Darren W. Engers, Craig W. Lindsley, Jerri M. Rook, P. Jeffrey Conn	58
11	mGlu ₇ potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome 2017 ·Science Translational Medicine ·Rocco G. Gogliotti, (unknown), Nicole M. Fisher, J. Paige Adams, Rocio Zamorano, Adam G. Walker, Anna L. Blobaum, Darren W. Engers, Corey R. Hopkins, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, Zixiu Xiang, P. Jeffrey Conn, Colleen M. Niswender	63
12	Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotype 2017 ·Bioorganic & Medicinal Chemistry Letters ·Aaron M. Bender, Rebecca L. Weiner, Vincent B. Luscombe, Hyekyung P. Cho, Colleen M. Niswender, Darren W. Engers, Thomas M. Bridges, P. Jeffrey Conn, Craig W. Lindsley	2
13	Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping 2017 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Julie L. Engers, Sichen Chang, Xiaoyan Zhan, Rebecca L. Weiner, Vincent B. Luscombe, Alice L. Rodriguez, Hyekyung P. Cho, Colleen M. Niswender, Thomas M. Bridges, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley	14
14	Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus 2015 ·Journal of Neuroscience ·(unknown), Adam G. Walker, Dipanwita Ghose, Brad A. Grueter, Darren W. Engers, (unknown), Craig W. Lindsley, Zixiu Xiang, P. Jeffrey Conn, Colleen M. Niswender	37
15	Discovery and Characterization of a Potent and Selective Inhibitor of Aedes aegypti Inward Rectifier Potassium Channels 2014 ·PLoS ONE ·Rene Raphemot, Matthew F. Rouhier, Daniel R. Swale, Emily Days, C. David Weaver, Kimberly M. Lovell, (unknown), Darren W. Engers, (unknown), Corey R. Hopkins, Peter M. Piermarini, Jerod S. Denton	42
16	Synthesis and structure–activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of Dorsomorphin: The discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe 2013 ·Bioorganic & Medicinal Chemistry Letters ·Darren W. Engers, Audrey Y. Frist, Craig W. Lindsley, Charles C. Hong, Corey R. Hopkins	71
17	Identification and Characterization of a Compound That Protects Cardiac Tissue from Human Ether-à-go-go-related Gene (hERG)-related Drug-induced Arrhythmias 2012 ·Journal of Biological Chemistry ·F Potet, (unknown), (unknown), Corey R. Hopkins, Raghav Venkataraman, Svetlana Z. Stepanovic, L. Michelle Lewis, Emily Days, Veniamin Y. Sidorov, Darren W. Engers, Beiyan Zou, David Afshartous, Alfred L. George, Courtney Campbell, Jeffrey R. Balser, Min Li, Franz Baudenbacher, Craig W. Lindsley, C. David Weaver, Sabina Kupershmidt	21
18	The Metabotropic Glutamate Receptor 4-Positive Allosteric Modulator VU0364770 Produces Efficacy Alone and in Combination with l-DOPA or an Adenosine 2A Antagonist in Preclinical Rodent Models of Parkinson’s Disease 2011 ·Journal of Pharmacology and Experimental Therapeutics ·Carrie K. Jones, Michael Bubser, Analisa D. Thompson, Jonathan W. Dickerson, N. Turle-Lorenzo, Marianne Amalric, Anna L. Blobaum, Thomas M. Bridges, Ryan D. Morrison, Satyawan Jadhav, Darren W. Engers, (unknown), (unknown), J. Scott Daniels, Craig W. Lindsley, Corey R. Hopkins, P. Jeffrey Conn, Colleen M. Niswender	81
19	Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Darren W. Engers, Colleen M. Niswender, Alice L. Rodriguez, Daryl F. Venable, P. Jeffrey Conn, Craig W. Lindsley	37
20	Recent progress in the development of mGluR4 positive allosteric modulators for the treatment of Parkinson's disease. 2009 ·PubMed ·Craig W. Lindsley, Colleen M. Niswender, Darren W. Engers, Corey R. Hopkins	29

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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