Giles A. Brown

1.1k citations

17 papers · 455 indexed · h-index 13

Impact in

Physiology top 5%
- Adenosine and Purinergic Signaling
Cellular and Molecular Neuroscience
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research

Papers in

Cellular and Molecular Neuroscience 7
- Neuropeptides and Animal Physiology 4
- Neuroscience and Neuropharmacology Research 4
Organic Chemistry 8
- Synthesis of β-Lactam Compounds 6
- Synthesis and Catalytic Reactions 5
- Asymmetric Synthesis and Catalysis 3
- Oxidative Organic Chemistry Reactions 2

Co-authors: Gary A. Molander Miles Congreve J.A. Christopher Stephen P. Andrews Yvan Le Huérou Timothy Gallagher Neil J. Hales Alexandra Borodovsky
Journals: Journal of the Chemical Society Perkin Transactions 1 (4 papers)British Journal of Clinical Pharmacology (2 papers)The Journal of Organic Chemistry (2 papers)Scientific Reports (1 paper)Chemical Communications (1 paper)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Giles A. Brown

17 papers receiving 444 citations

Peers

Countries citing papers authored by Giles A. Brown

Since Specialization

Citations

This map shows the geographic impact of Giles A. Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Giles A. Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Giles A. Brown more than expected).

Fields of papers citing papers by Giles A. Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Giles A. Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Giles A. Brown. The network helps show where Giles A. Brown may publish in the future.

Co-authors

The 25 scholars most cited alongside Giles A. Brown, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Giles A. Brown Line = papers co-authored together Giles A. Brown links everyone, so they are left out of the graph.

All Works

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17 of 17 papers shown

#	Work
1	Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits Nature Communications ·Jon Palacios-Filardo, Matt Udakis, Giles A. Brown, Benjamin G. Tehan, Miles Congreve, Pradeep J. Nathan, Alastair Brown, Jack R. Mellor	2021	26
2	Safety, pharmacokinetics and exploratory pro-cognitive effects of HTL0018318, a selective M1 receptor agonist, in healthy younger adult and elderly subjects: a multiple ascending dose study Alzheimer s Research & Therapy ·C. J. G. Bakker, Tim Tasker, Jan Liptrot, Ellen P. Hart, Erica S. Klaassen, Robert J. Doll, Giles A. Brown, Alastair Brown, Miles Congreve, Malcolm Weir, Fiona H. Marshall, David M. Cross, Geert Jan Groeneveld, Pradeep J. Nathan	2021	13
3	Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M₁‐acetylcholine receptor agonist: A randomized cross‐over trial British Journal of Clinical Pharmacology ·C. J. G. Bakker, Samantha Prins, Jan Liptrot, Ellen P. Hart, Erica S. Klaassen, Giles A. Brown, Alastair Brown, Miles Congreve, Malcolm Weir, Fiona H. Marshall, Jasper Stevens, David M. Cross, Tim Tasker, Pradeep J. Nathan, Geert Jan Groeneveld	2021	3
4	First‐in‐man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M₁‐receptor partial agonist for the treatment of dementias British Journal of Clinical Pharmacology ·C. J. G. Bakker, Tim Tasker, Jan Liptrot, Ellen P. Hart, Erica S. Klaassen, Samantha Prins, Thalia F. van der Doef, Giles A. Brown, Alastair Brown, Miles Congreve, Malcolm Weir, Fiona H. Marshall, David M. Cross, Geert Jan Groeneveld, Pradeep J. Nathan	2020	13
5	Recent Developments in Therapeutic Peptides for the Glucagon-like Peptide 1 and 2 Receptors Journal of Medicinal Chemistry ·Rie Suzuki, Giles A. Brown, J.A. Christopher, Conor C. G. Scully, Miles Congreve	2019	42
6	Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals Scientific Reports ·Prakash Rucktooa, R.K. Cheng, Elena Segala, Tian Geng, James C. Errey, Giles A. Brown, Roger Cooke, Fiona H. Marshall, A.S. Dore	2018	69
7	Targeting adenosine A_2A receptor antagonism for treatment of cancer Expert Opinion on Drug Discovery ·Miles Congreve, Giles A. Brown, Alexandra Borodovsky, Michelle L. Lamb	2018	45
8	Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol–Bound β1-Adrenergic Receptor Molecular Pharmacology ·Tomomi Sato, Jillian G. Baker, Tony Warne, Giles A. Brown, Andrew G. W. Leslie, Miles Congreve, Christopher G. Tate	2015	21
9	Structure‐Based and Fragment‐Based GPCR Drug Discovery ChemMedChem ·Stephen P. Andrews, Giles A. Brown, J.A. Christopher	2013	56
10	Sequenced Reactions with Samarium(II) Iodide. Sequential Intramolecular Reformatsky/Nucleophilic Acyl Substitution Reactions for the Synthesis of Medium-Sized Carbocycles The Journal of Organic Chemistry ·Gary A. Molander, Giles A. Brown, I. Gràcia	2002	33
11	The azomethine ylide strategy for β-lactam synthesis. Azapenams and 1-azacephams Journal of the Chemical Society Perkin Transactions 1 ·David Brown, Giles A. Brown, Mark D. Andrews, Jonathan M. Large, Dominique Urban, Craig P. Butts, Neil J. Hales, Timothy Gallagher	2002	23
12	The azomethine ylide strategy for β-lactam synthesis. An evaluation of alternative pathways for azomethine ylide generation Journal of the Chemical Society Perkin Transactions 1 ·Giles A. Brown, Sarah R. Martel, Richard Wisedale, J.P.H. Charmant, Neil J. Hales, Colin W. G. Fishwick, Timothy Gallagher	2001	9
13	Sequenced Reactions with Samarium(II) Iodide. Sequential Intramolecular Barbier Cyclization/Grob Fragmentation for the Synthesis of Medium-Sized Carbocycles The Journal of Organic Chemistry ·Gary A. Molander, Yvan Le Huérou, Giles A. Brown	2001	55
14	The azomethine ylide strategy for β-lactam synthesis. A comprehensive mechanistic evaluation Journal of the Chemical Society Perkin Transactions 1 ·David Brown, Giles A. Brown, Sarah R. Martel, Denis Planchenault, Evelyn Turmes, Kenneth E. Walsh, Richard Wisedale, Neil J. Hales, Colin W. G. Fishwick, Timothy Gallagher	2001	4
15	Trapping highly reactive dipolarophiles. Exploiting the mechanism associated with the azomethine ylide strategy for β-lactam synthesis Journal of the Chemical Society Perkin Transactions 1 ·Giles A. Brown, K.M. Anderson, Jonathan M. Large, Denis Planchenault, Dominique Urban, Neil J. Hales, Timothy Gallagher	2001	14
16	The Azomethine Ylid Strategy in β-Lactam Synthesis. Application to Selenapenams Tetrahedron ·Giles A. Brown, K.M. Anderson, Martin Murray, Timothy Gallagher, Neil J. Hales	2000	20
17	Aldehydes and ketones as dipolarophiles: application to the synthesis of oxapenams Chemical Communications ·Mark D. Andrews, Giles A. Brown, J.P.H. Charmant, Torren M. Peakman, Arlene Rebello, Kenneth E. Walsh, Timothy Gallagher, Neil J. Hales	1999	9

About Giles A. Brown

Giles A. Brown is a scholar working on Cellular and Molecular Neuroscience, Organic Chemistry, Physiology, Pharmacology and Pharmacology, having authored 17 papers that have together received 455 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (7 papers), Synthesis of β-Lactam Compounds (6 papers), Synthesis and Catalytic Reactions (5 papers), Neuropeptides and Animal Physiology (4 papers), Neuroscience and Neuropharmacology Research (4 papers), Asymmetric Synthesis and Catalysis (3 papers), Cholinesterase and Neurodegenerative Diseases (2 papers) and Oxidative Organic Chemistry Reactions (2 papers). The work is most often cited by research in Physiology (64 citations), Cellular and Molecular Neuroscience (122 citations), Organic Chemistry (173 citations), Molecular Biology (241 citations) and Toxicology (11 citations). Giles A. Brown has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Gary A. Molander, Miles Congreve, J.A. Christopher, Stephen P. Andrews, Yvan Le Huérou, Timothy Gallagher, Neil J. Hales, Alexandra Borodovsky, Michelle L. Lamb and I. Gràcia. Their work appears in journals such as Journal of the Chemical Society Perkin Transactions 1, British Journal of Clinical Pharmacology, The Journal of Organic Chemistry, Scientific Reports and Chemical Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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