Steven M. Paul

25.7k citations

117 papers · 16.4k indexed · 5 hit papers · h-index 66

Physiology top 0.05%
Molecular Biology top 1%
Neurology top 0.05%
Cellular and Molecular Neuroscience top 0.2%
Pharmacology top 0.1%

Co-authors: Kelly R. Bales David M. Holtzman Ronald B. DeMattos Maia Parsadanian Jean‐Cosme Dodart David J. Cummins Anne M. Fagan Chantal Mathis
Topics: Alzheimer's disease research and treatments (79 papers)Cholinesterase and Neurodegenerative Diseases (21 papers)Neuroinflammation and Neurodegeneration Mechanisms (20 papers)
Cited by: Neurology Physiology Biological Psychiatry
Journals: Science Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Canada France

In The Last Decade

Steven M. Paul

116 papers receiving 16.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

2001 1.1k citations Ronald B. DeMattos, Kelly R. Bales et al. profile →
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

2011 887 citations Jungsu Kim, Ronald B. DeMattos et al. profile →
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

2000 726 citations David M. Holtzman, Kelly R. Bales et al. profile →
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

2002 705 citations Kelly R. Bales, Ronald B. DeMattos et al. profile →
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

2005 510 citations Xin Wu, Kelly R. Bales et al. profile →

Peers

Countries citing papers authored by Steven M. Paul

Since Specialization

Citations

This map shows the geographic impact of Steven M. Paul's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven M. Paul with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven M. Paul more than expected).

Fields of papers citing papers by Steven M. Paul

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven M. Paul. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven M. Paul. The network helps show where Steven M. Paul may publish in the future.

Co-authorship network of co-authors of Steven M. Paul

This figure shows the co-authorship network connecting the top 25 collaborators of Steven M. Paul. A scholar is included among the top collaborators of Steven M. Paul based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven M. Paul. Steven M. Paul is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Chocolate Brown HT Inhibits the Contractile Activity of the Small Intestinal Visceral Smooth Muscle in Male Albino Rats 2025 ·International Journal of Science and Healthcare Research ·(unknown),Steven M. Paul,(unknown),(unknown),Goutam Paul	0
2	Targeting apolipoprotein E for treating Alzheimer’s disease 2019 ·Neuroscience Letters ·Kelly R. Bales,Steven M. Paul	5
3	AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease 2018 ·PubMed ·Jonathan B. Rosenberg,Michael G. Kaplitt,Bishnu P. De,Alvin Chen,(unknown),(unknown),(unknown),Lingzhi Zhao,Rodolfo J Ricart Arbona,Sébastien Monette,Jonathan P. Dyke,Douglas Ballon,(unknown),Dolan Sondhi,Gregory A. Petsko,Steven M. Paul,Ronald G. Crystal	123
4	Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function 2018 ·Nature Communications ·Kenzo Koizumi,Yorito Hattori,Sung Ji Ahn,Izaskun Buendía,Antonio Ciacciarelli,Ken Uekawa,Gang Wang,(unknown),Lingzhi Zhao,Henning U. Voss,Steven M. Paul,Chris B. Schaffer,Laibaik Park,Costantino Iadecola	114
5	Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models 2016 ·Neurobiology of Aging ·Lingzhi Zhao,(unknown),Mayur Parmar,Mingjie Li,Stephen M. Kaminsky,Marı́a J. Chiuchiolo,Dolan Sondhi,Patrick M. Sullivan,David M. Holtzman,Ronald G. Crystal,Steven M. Paul	71
6	TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy 2016 ·Neuron ·Peng Yuan,Carlo Condello,C. Dirk Keene,Yaming Wang,Thomas D. Bird,Steven M. Paul,Wenjie Luo,Marco Colonna,David Baddeley,Jaime Grutzendler	135
7	Hypertension enhances A β -induced neurovascular dysfunction, promotes β -secretase activity, and leads to amyloidogenic processing of APP 2015 ·Journal of Cerebral Blood Flow & Metabolism ·Giuseppe Faraco,Laibaik Park,Ping Zhou,Wenjie Luo,Steven M. Paul,Josef Anrather,Costantino Iadecola	133
8	Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree 2015 ·PLoS ONE ·(unknown),Jiangang Liu,Rachelle J. Sells Galvin,Jeffrey L. Dage,Janice A. Egeland,Rosamund C. Smith,Kalpana Merchant,Steven M. Paul	26
9	Macrophage-Mediated Degradation of β-Amyloid via an Apolipoprotein E Isoform-Dependent Mechanism 2009 ·Journal of Neuroscience ·Lingzhi Zhao,Suizhen Lin,Kelly R. Bales,Valentina Gelfanova,Deanna Koger,Cynthia DeLong,John E. Hale,Feng Liu,Jesse M. Hunter,Steven M. Paul	60
10	Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease 2008 ·Journal of Clinical Investigation ·Suzanne E. Wahrle,Hong Jiang,Maia Parsadanian,Jungsu Kim,Aimin Li,Amanda Knoten,Sanjay Jain,Veronica Hirsch‐Reinshagen,Cheryl L. Wellington,Kelly R. Bales,Steven M. Paul,David M. Holtzman	311
11	Liver X Receptor-Mediated Gene Regulation and Cholesterol Homeostasis in Brain: Relevance to Alzheimers Disease Therapeutics 2007 ·Current Alzheimer Research ·Guoqing Cao,Kelly R. Bales,Ronald B. DeMattos,Steven M. Paul	63
12	Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms 2006 ·Neurobiology of Aging ·David A. Costa,Jennifer R. Cracchiolo,Adam D. Bachstetter,Tiffany F. Hughes,Kelly R. Bales,Steven M. Paul,Ronald F. Mervis,Gary W. Arendash,Huntington Potter	181
13	Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice 2005 ·Journal of Clinical Investigation ·Robert P. Brendza,Brian J. Bacskai,John R. Cirrito,Kelly Simmons,Jesse Skoch,William E. Klunk,Chester A. Mathis,Kelly R. Bales,Steven M. Paul,Bradley T. Hyman,David M. Holtzman	23
14	ApoAI Deficiency Results in Marked Reductions in Plasma Cholesterol But No Alterations in Amyloid-β Pathology in a Mouse Model of Alzheimer's Disease-Like Cerebral Amyloidosis 2004 ·American Journal Of Pathology ·Anne M. Fagan,(unknown),Jennie Taylor,Maia Parsadanian,Michael Spinner,Melanie Watson,John Denis Fryer,Suzanne E. Wahrle,Kelly R. Bales,Steven M. Paul,David M. Holtzman	46
15	Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer’s transgenic mouse lines differing in Aβ deposition 2004 ·Behavioural Brain Research ·Ralph E. Leighty,Lars Nilsson,Huntington Potter,David A. Costa,(unknown),Kelly R. Bales,Steven M. Paul,Gary W. Arendash	40
16	Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease 2002 ·PMC ·Richard E. Hartman,Helmut Laurer,Luca Longhi,Kelly R. Bales,Steven M. Paul,Tracy K. McIntosh,David M. Holtzman	1
17	Minocycline markedly protects the neonatal brain against hypoxic‐ischemic injury 2002 ·Annals of Neurology ·(unknown),Byung Hee Han,Yansheng Du,(unknown),Steven M. Paul,David M. Holtzman	262
18	Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid β-peptide deposition in homozygous APP V717F transgenic mice 2000 ·Acta Neuropathologica ·Michael C. Irizarry,Bonnie Cheung,G. William Rebeck,Steven M. Paul,Kelly R. Bales,Bradley T. Hyman	77
19	Overexpression of the Neuritotrophic Cytokine S100β Precedes the Appearance of Neuritic β‐Amyloid Plaques in APPV717F Mice 2000 ·Journal of Neurochemistry ·Jin G. Sheng,Robert E. Mrak,Kelly R. Bales,Barbara Cordell,Steven M. Paul,Richard A. Jones,S Woodward,Xue Zhou,(unknown),W. Sue T. Griffin	67
20	Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons 1997 ·PMC ·Binhui Ni,Xin Wu,Yansheng Du,Yuan Su,Elizabeth Hamilton‐Byrd,(unknown),Paul R. Rosteck,Guy G. Poirier,Steven M. Paul	9

About Steven M. Paul

Steven M. Paul is a scholar working on Physiology, Neurology and Cellular and Molecular Neuroscience, having authored 117 papers that have together received 16.4k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (79 papers), Cholinesterase and Neurodegenerative Diseases (21 papers) and Neuroinflammation and Neurodegeneration Mechanisms (20 papers). The work is most often cited by research in Neurology (3.8k citations), Physiology (11.6k citations) and Biological Psychiatry (978 citations). Steven M. Paul has collaborated with scholars based in United States, Canada and France. Frequent co-authors include Kelly R. Bales, David M. Holtzman, Ronald B. DeMattos, Maia Parsadanian, Jean‐Cosme Dodart, David J. Cummins, Anne M. Fagan, Chantal Mathis, Xin Wu and Mark Odell. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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